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Elsevier

Books in Life sciences

  • Biomarkers, Diagnostics and Precision Medicine in the Drug Industry

    Critical Challenges, Limitations and Roadmaps for the Best Practices
    • 1st Edition
    • Abdel Halim
    • English
    The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline, as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerate the time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. This book aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies, which includes standard-of-care approved assays as well as for-investigational-... and for-research-use-onl... assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. This book serves as a reference to drug developers, IVD providers, clinical labs, healthcare givers, academicians, and researchers for best practices to help increase the probability of success in drug development and improve patient management.

  • Parasiticide Screening

    Volume 2: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods
    • 1st Edition
    • Alan A. Marchiondo + 2 more
    • English
    Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestatio... Methods, Volume Two presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds.

  • Parasiticide Screening

    Volume 1: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods
    • 1st Edition
    • Alan A. Marchiondo + 2 more
    • English
    Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestatio... Methods, Volume One presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds.

  • Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

    The Chemical and Pharmacological Basis of their Action
    • 1st Edition
    • Solomon Habtemariam
    • English
    Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/developmen... nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries.

  • Innovative Thermal and Non-Thermal Processing, Bioaccessibility and Bioavailability of Nutrients and Bioactive Compounds

    • 1st Edition
    • Francisco J. Barba + 3 more
    • English
    Innovative Thermal and Nonthermal Processing, Bioacessibility and Bioavailability of Nutrients and Bioactive Compounds presents the implications of conventional and innovative processing on the nutritional and health aspects of food products. Chapters cover the relationship between gastronomic science, nutrition and food science in the development of healthy products, introduce the most commonly used conventional and innovative approaches to preserve foods and extract valuable compounds, describe how processing affects bioavailability and bioaccessibility of lipids, particularly fatty acids, protein, amino acids and carbohydrates, and discuss how processing affects bioavailability and bioaccessibility of minerals, water-soluble vitamins, and fat soluble vitamins. Final sections cover processing, bioavailability and bioaccessibility of bioactive compounds, describing how processing (conventional and non-conventional) is affecting to bioavailability and bioaccessibility of bioactive sulphur compounds, polyphenols, flavonoids, and bioactive peptides.

  • Nutrients in Beverages

    Volume 12: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Nutrients in Beverages, Volume Twelve, in the Science of Beverages series, introduces the role of nutrients in beverages and provides details into the biological effects of beverage ingredients by presenting their nutritional properties and characterization. This scientific reference covers both the current state-of-the-art and future trends in the beverage industry, and is designed as a comprehensive guide to this area of research. Detailed research information is presented to not only help researchers and students understand the nature of the challenges associated with incorporating nutrients, but to also help strengthen the knowledge transfer between research institutions and industry.

  • Alternative Swine Management Systems

    • 1st Edition
    • Ioan Hutu + 1 more
    • English
    Alternative Swine Management Systems examines technologically humane substitutions for swine production, focusing specifically on hoop structure systems. Benefits of these alternatives include enhanced animal welfare and reduced capital cost. From small holders involved in low input pig farms, to larger commercial operations, this book instructs users on new technology to improve the quality of animal production, animal welfare and environmental protection points.

  • Smart Bioremediation Technologies

    Microbial Enzymes
    • 1st Edition
    • Pankaj Bhatt
    • English
    Smart Bioremediation Technologies: Microbial Enzymes provides insights into the complex behavior of enzymes and identifies metabolites and their degradation pathways. It will help readers work towards solutions for sustainable medicine and environmental pollution. The book highlights the microbial enzymes that have replaced many plant and animal enzymes, also presenting their applications in varying industries, including pharmaceuticals, genetic engineering, biofuels, diagnostics and therapy. In addition, new methods, including genomics and metagenomics, are being employed for the discovery of new enzymes from microbes. This book brings all of these topics together, representing the first resource on how to solve problems in bioremediation.

  • Single-Cell Omics

    Volume 1: Technological Advances and Applications
    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

  • Safety and Practice for Organic Food

    • 1st Edition
    • Debabrata Biswas + 1 more
    • English
    Safety and Practice for Organic Food covers current food safety issues and trends. It provides detailed information on all organic and pasture practices including produce-only, farm-animal-only or integrated crop-livestock farming, as well as the impact of these practices on food safety and foodborne infections. The book explores food products that organic, integrated and traditional farming systems are contributing to consumers. As the demand for organic food products grows faster than ever, this book discusses current and improved practices for safer products. Moreover, the book explores progressive directions, such as the application of next-generation sequencing and genomics to aid in the understanding of the microbial ecology of the agro-environment and how farmer education can contribute to sustainable and safe food. Safety and Practice for Organic Food is a unique source of organic agricultural practices and food production for researchers, academics and professionals at agriculture-based universities and colleges who are involved in food science, animal sciences including poultry science, food safety, food microbiology, plant science and agricultural extension. This book is also an excellent source of information for regulators and federal government officials (USDA, FDA, EPA) and the food processing industry.

  • Advances in Genetics

    • 1st Edition
    • Volume 104
    • English
    Advances in Genetics, Volume 104, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

  • Functional and Medicinal Beverages

    Volume 11: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Functional and Medicinal Beverages, Volume Eleven, in the Science of Beverages series, discusses one of the fastest growing sectors in the food industry. As the need for research and development increases based on consumer demand, the information in this volume is essential. This reference includes the latest research trends, nutritive and medicinal ingredients, and analytical techniques to identify health beneficial elements. The contents of the book will bring readers up-to-date on the field, thus making it useful for researchers and graduate students in various fields across the food sciences and technology.

  • Pharmacoepigenetics

    • 1st Edition
    • Volume 10
    • Ramón Cacabelos
    • English
    Pharmacoepigenetics provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.

  • Membrane Transporters in the Pathogenesis of Cardiovascular and Lung Disorders

    • 1st Edition
    • Volume 83
    • English
    Membrane Transporters in the Pathogenesis of Cardiovascular and Lung Disorders, Volume 83, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this volume presenting chapters from recognized experts on topics such as cardiotonic steroids, Na+, K+ pumps and vascular fibrosis, purinergic signaling in the lung, structural models of a2-subunit N-termini and binding interfaces, ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients, the Na, K-ATPase alpha2 isoform in cardiovascular pathologies, the role of cell swelling and volume-sensitive ion channels in stroke pathology, structure-function relationships in the renal NaCl cotransporter, and more.

  • Emotion and Cognition

    • 1st Edition
    • Volume 247
    • English
    Emotion and Cognition, Volume 246, consists of 16 chapters on recent scientific advances in emotion and cognition research. The chapters include theoretical, review, and empirical chapters presenting original data on interactions between emotion and cognition. Chapters touch on a variety of topics, including Common and different mechanisms underlying the processing of extrinsic and intrinsic emotion, Looming fear stimuli broadens attention in a local-global letter task, Reading thoughts and feelings in other people – how age shapes empathic accuracy, How does aging influence emotion-cognition links?, and The Motivational Dimensional Model of affect: A review of the past 10 years, and more.

  • The Core Model

    A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care
    • 1st Edition
    • Ibis Sanchez Serrano
    • English
    The Core Model: A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care develops the innovative core model, an organizational research and design paradigm and economic theory that proposes a collaborative approach to resolving global health issues and improving the productivity of drug development. The model proposes that scientific collaboration does not occur in an unstructured manner, but actually takes place within a highly structured order where knowledge is transferred, integrated and finally translated into commercial products. An understanding of this model will help solve the global pharmaceutical industry´s productivity problems and address important global health care and economic issues. This book is useful to researchers, advanced students, regulators, and management in pharmaceutical industries, as well as healthcare professionals, those working in health economics, and those interested in scientific innovation processes.

  • Encyclopedia of Tissue Engineering and Regenerative Medicine

    • 1st Edition
    • Rui L. Reis
    • English
    Encyclopedia of Tissue Engineering and Regenerative Medicine, Three Volume Set provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine.

  • Nutraceutical and Functional Food Regulations in the United States and around the World

    • 3rd Edition
    • Debasis Bagchi
    • English
    Nutraceutical and Functional Food Regulations in the United States and Around the World, Third Edition addresses the latest regulatory requirements designed to ensure the safe production and delivery of these valuable classes of foods. The book is well recognized, showing how food and nutrition play a critical role in enhancing human performance, and in overall health. The book discusses the scope, importance and continuing growth opportunities in the nutraceutical and functional food industries, exploring the acceptance and demand for these products, regulatory hurdles, the intricate aspects of manufacturing procedures, quality control, global regulatory norms and guidelines.

  • NETosis

    Immunity, Pathogenesis and Therapeutics
    • 1st Edition
    • Geeta Rai
    • English
    NETosis: Immunity, Pathogenesis and Therapeutics takes a focused approach to the clinical aspects of NETosis and drug development, bringing critical findings. Chapters introduce NETosis, consider mechanisms and antimicrobial strategies regulating NETosis, examine NETosis in neonates, explore the role of NETosis in autoimmunity, delve into NETosis and other diseases, and present therapeutic approaches for dysregulated NETosis. Since Brinkamm, et al, discovered an unrecognized neutrophil anti-microbial mechanism responsible for the extracellular killing of invading pathogens in 2004, the novel process in which nuclear chromatin de-condenses and DNA is ejected into the extra cellular environment, trapping and inactivating tissue pathogens has rapidly evolved.

  • The Mechanics of Inhaled Pharmaceutical Aerosols

    An Introduction
    • 2nd Edition
    • Warren H. Finlay
    • English
    The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction, Second Edition provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols. This revised edition will allow researchers in the field to gain a thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. Chapters consider mechanics and deposition, specifically in the respiratory tract, while others discuss the mechanics associated with the three existing types of pharmaceutical inhalation devices. This text will be very useful for academics and for courses taught at both undergraduate and graduate levels. Because of the interdisciplinary nature of this book, it will also serve a wide audience that includes engineers and scientists involved with inhaled aerosol therapies.

  • Saving Food

    Production, Supply Chain, Food Waste and Food Consumption
    • 1st Edition
    • Charis M. Galanakis
    • English
    Saving Food: Production, Supply Chain, Food Waste and Food Consumption presents the latest developments on food loss and waste. Emphasis is placed on global issues, the environmental impacts of food consumption and wasted food, wasted nutrients, raising awareness via collaborative networks and actions, the effect of food governance and policy in food losses, promotion of sustainable food consumption, food redistribution, optimizing agricultural practices, the concept of zero waste, food security and sustainable land management, optimizing food supply and cold chains, food safety in supply chain management, non-thermal food processing/preservat... technologies, food waste prevention/reduction... food waste valorization and recovery. Intended to be a guide for all segments of the food industry aiming to adapt or further develop zero waste strategies, this book analyzes the problem of food waste from every angle and provides critical information on how to minimize waste.

  • Taxonomic Guide to Infectious Diseases

    Understanding the Biologic Classes of Pathogenic Organisms
    • 2nd Edition
    • Jules J. Berman
    • English
    Taxonomic Guide to Infectious Diseases: Understanding the Biologic Classes of Pathogenic Organisms, Second Edition tackles the complexity of clinical microbiology by assigning every infectious organism to one of 40+ taxonomic classes and providing a description of the defining traits that apply to all the organisms within each class. This edition is an updated, revised and greatly expanded guide to the classes of organisms that infect humans. This book will provide students and clinicians alike with a simplified way to understand the complex fields of clinical microbiology and parasitology.

  • Metabolism, Structure and Function of Plant Tetrapyrroles: Introduction, Microbial and Eukaryotic Chlorophyll Synthesis and Catabolism

    • 1st Edition
    • Volume 90
    • English
    Metabolism, Structure and Function of Plant Tetrapyrroles, Volume 90, the latest release in the Advances in Botanical Research series is a compilation of the current state-of-the-art on the topic. Chapters in this new release cover Tetrapyrrole Pigments of Photosynthetic Antennae and Reaction Centers of Higher Plants: Biochemistry, Biophysics, Functions, Molecular Mechanism of Antenna Regulation, Applications, Chlorophyll c: Synthesis, Occurrence, Light-Harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Proteins (FCP), Chlorophyll d and f: Synthesis, Occurrence, Light-harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Protein Complexes, Analysis of Chlorophyll, Precursors and Derivatives by New High-Performance Liquid Chromatography and Mass Spectrometry, and much more.

  • The Immortal Germline

    • 1st Edition
    • Volume 135
    • English
    The Immortal Germline, Volume 135 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Balbiani body, germ plasm and polarity, Wolbachia and the germline, Human germ line biology, Reproduction/immunit... and sperm success, Mammalian spermatogenesis, Reproduction/regener... and germ cells in planarians, Germline stem cell homeostasis, Germline soma interactions/sex determination, Reconstituting the mouse germ-cell specification pathway in vitro, Maternal Germ line inheritance of mitochondria, Transposon strategies, and more.

  • Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part B

    • 1st Edition
    • Volume 622
    • English
    Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part B, Volume 622, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting chapters that cover the Design of optogenetic proteins, the Application of optogenetic proteins, Antibody aggregation mechanism probed by a fluorescently-labele... antibody with fluorescence correlation spectroscopy, Bimane labeling of B-arrestins to measure their interaction with GPCRs, Reversible biotinylation of proteins for investigating their interaction with partners, Chemical biology approaches to study RNA cytidine acetylation, Salt sensitive intein in robotic production of peptides, and much more.

  • Proteins: Sustainable Source, Processing and Applications

    • 1st Edition
    • Charis M. Galanakis
    • English
    Proteins: Sustainable Source, Processing and Applications addresses sustainable proteins, with an emphasis on proteins of animal origin, plant-based and insect proteins, microalgal single cell proteins, extraction, production, the stability and bioengineering of proteins, food applications (e.g. encapsulation, films and coatings), consumer behavior and sustainable consumption. Written in a scientific manner to meet the needs of chemists, food scientists, technologists, new product developers and academics, this book addresses the health effects and properties of proteins, highlights sustainable sources, processes and consumption models, and analyzes the potentiality of already commercialized processes and products. This book is an integral resource that supports the current applications of proteins in the food industry, along with those that are currently under development.

  • Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection

    • 1st Edition
    • Naseer Ahmed
    • English
    Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection.Pat... of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection.

  • Biomaterials and Bionanotechnology

    • 1st Edition
    • English
    Biomaterials and Bionanotechnology examines the current state of the field within pharmaceutical sciences and concisely explains the history of biomaterials including key developments. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biomaterials and bionanotechnology within drug discovery and drug development. Each chapter delves into a particular aspect of this fast-moving field to cover the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable dosage form, with particular focus on biomaterials and bionanomaterials. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, food and related industries as well as advanced students in these fields.

  • Model Ecosystems in Extreme Environments

    • 1st Edition
    • Volume 2
    • English
    Model Ecosystems in Extreme Environments, Second Edition examines ecosystems at the most extreme habitats and their interaction with the environment, providing a key element in our understanding of the role and function of microorganisms in nature. The book highlights current topics in the field, such as biodiversity and the structure of microbial communities in extreme environments, the effects of extreme environmental conditions on microbial ecosystems, and ecological and evolutionary interactions in extreme environments, among other topics. It will be a valuable text for faculty and students working with extremophiles and/or microbial ecology and researchers, including astrobiologists, biologists, evolutionary scientists, astronomers, geochemists and oceanographers.

  • Food Applications of Nanotechnology

    • 1st Edition
    • Volume 88
    • English
    Food Applications of Nanotechnology, Volume 88, consolidates the literature on recent developments in nanotechnology, addressing production, safety and nutritional aspects pertaining to foods and nutraceuticals. Chapters in this new release include Assembled protein nanoparticles in food and nutrition applications, Nano-scale carbohydrate Materials in food/nutrition/agric... applications, Nanotechnology-based colloidal delivery systems in foods, Electrospinning and Electrospraying in food, Bioavailability of nanotechnology-based bioactives and nutraceuticals, and more.

  • Biochemistry of Collagens, Laminins and Elastin

    Structure, Function and Biomarkers
    • 2nd Edition
    • Morten Karsdal
    • English
    There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease.

  • Self-assessment Questions for Clinical Molecular Genetics

    • 1st Edition
    • Haiying Meng
    • English
    Review Questions of Clinical Molecular Genetics presents a comprehensive study guide for the board and certificate exams presented by the American College of Medical Genetics and Genomics (ACMG) and the American Board of Medical Genetics and Genomics (ABMGG). It provides residents and fellows in genetics and genomics with over 1,000 concise questions, ranging from topics in cystic fibrosis, to genetic counseling, to trinucleotide repeat expansion disorders. It puts key points in the form of questions, thus challenging the reader to retain knowledge. As board and certificate exams require knowledge of new technologies and applications, this book helps users meet that challenge.

  • Genome Chaos

    Rethinking Genetics, Evolution, and Molecular Medicine
    • 1st Edition
    • Henry H. Heng
    • English
    Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine.

  • Neuroscience of the Nonconscious Mind

    • 1st Edition
    • Rajendra Badgaiyan
    • English
    Neuroscience of the Nonconscious Mind includes novel concepts and insights on the brain mechanisms that control nonconscious mental functions, some of which were developed in the author’s laboratory. The book describes neuroscience of conventional nonconscious mental functions, along with not so conventional functions like creativity, hypnosis and extrasensory perception, thus making it a very unique reference. This thought provoking book for students of mind, brain and consciousness will help explain concepts and introduce the science behind the nonconscious.

  • Pregnancy and the Pharmaceutical Industry

    The Movement towards Evidence-Based Pharmacotherapy for Pregnant Women
    • 1st Edition
    • Kristine E. Shields
    • English
    Pregnancy and the Pharmaceutical Industry: The Movement towards Evidence-Based Care for Pregnant Women explores the issues surrounding the decision to undertake clinical trials with pregnant women. There is currently a lack of data on the safety and effectiveness of medications used during pregnancy as it is impossible to extrapolate that information from drug studies on men and non-pregnant women. As a majority of pregnant women confront a medical condition during their pregnancy, from simple pain, to ongoing or new medical issues, this book quantifies the current absence of pregnant women in drug studies and identifies ethical issues, barriers, litigation fears and opportunities. Those in the pharmaceutical industry, IRB members who approve or deny drug study plans, doctors, nurses and midwives working in obstetrics or involved in conducting studies at their institutions will find this book an essential resource.

  • Chromatin Signaling and Neurological Disorders

    • 1st Edition
    • Volume 12
    • English
    Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases. In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.

  • Human Brainstem

    Cytoarchitecture, Chemoarchitecture, Myeloarchitecture
    • 1st Edition
    • George Paxinos + 2 more
    • English
    Human Brainstem: Cytoarchitecture, Chemoarchitecture, Myeloarchitecture explores how the human brainstem has been impeded by the unavailability of an up-to-date, comprehensive, diagrammatic and photographic atlas. Now, with the first detailed atlas on the human brainstem in more than twenty years, this book presents an accurate, comprehensive and convenient reference for students, researchers and pathologists.

  • Epigenetics and Regeneration

    • 1st Edition
    • Volume 11
    • English
    Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics.

  • Wildlife Conservation in Africa

    A Scientific Approach
    • 1st Edition
    • S.S. Ajayi
    • English
    Wildlife Conservation in Africa: A Scientific Approach presents comprehensive management strategies for the consumptive and non-consumptive utilization of wildlife across Sub-Saharan Africa. It describes African economies that are currently dependent on wildlife resources and prescribes strategies for conserving biodiversity in both forests and animals in ecosystems across the continent. The book covers the history and current status of how Africa’s culture, traditions, healthcare and food sources are woven intricately around the local wildlife and resources. It is a necessary resource for researchers and practitioners in wildlife and ecological conservation, but is also useful for administrators and managers of protected areas.

  • Advances in Agronomy

    • 1st Edition
    • Volume 156
    • English
    Advances in Agronomy, Volume 156, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 107
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 107, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters covering the roles and applications of siderophores, biological oxidation of iron sulphides, production of biomass and biofuel feedstocks from microalgae, advances in the microbial ecology of biohydrometallurgy, bacterial synthesis of Se nanoparticles, and siderophores in environmental research, amongst other discussions.

  • Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part A

    • 1st Edition
    • Volume 621
    • English
    Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part A, Volume 621, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this volume covering Site-directed ethylation of membrane proteins for measuring conformational transitions in lipid bilayers, the Design and synthesis of fluorescent activity probes for protein phosphatases, Stains, Utilizing split-nanoLuc fragments as luminescent probes for protein solubility in living cells, SH2-domain based sensor for intracellular recognition of sulfo-tyrosine, DNA-encoded immunoglobulins for detection of parasites, An engineered TEV protease – calmodulin fusion based sensor for neuronal calcium recording, and much more.

  • Trends in Personalized Nutrition

    • 1st Edition
    • Charis M. Galanakis
    • English
    Trends in Personalized Nutrition explores the topic of personalized nutrition from multiple angles, addressing everything from consumer acceptance, to policies and cognitive dissonance. Sections in the book cover epigenetics, nutrigenomics, predicting glycemic response, and metabolomics and the role of bacteria. In addition, the book explores diet, obesity and personalized nutrition for athletes, women, and infants and children, along with a section on the role of modern technology in the promotion of personalized nutrition. Nutritionists, food technologists, food chemists, new product developers, academics, and researchers and physicians working in the field of nutrition will find this to be a great reference.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 74
    • English
    Advances in Microbial Physiology, Volume 74, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The book contains updates in the field, with comprehensive chapters covering The electrifying physiology of Geobacter bacteria 30 years on, Adaptive morphogenesis in bacteria, Bacterial energetics and respiratory metabolism, Bacteria respiration during infection, Regulation of Organohalide Respiration, Bioenergetics of Campylobacter jejuni, Formate Hydrogenlyases, Bioenergetical Aspects of the Bacterial and Archaeal Hydrogen Metabolism, and more.

  • New Developments in Nanosensors for Pharmaceutical Analysis

    • 1st Edition
    • Sibel A. Ozkan + 1 more
    • English
    New Developments for Nanosensors in Pharmaceutical Analysis presents an overview of developments in nanosensor usage in pharmaceutical analysis, thereby helping pharmaceutical companies attain reliable, precise, and accurate analysis of pharmaceuticals. This book presents very simple, precise, sensitive, selective, fast, and relatively inexpensive methods for pre-treatment, prior to analysis. These methods may be considered for further application in clinical studies and assays. The book includes the manufacturing of sensors for pharmaceutical analysis at nano- or smaller scales, and gives simple and relatable designs for the fabrication of sensors. Twelve chapters cover an introduction to the topic, immobilization techniques, mechanism effect of nanomaterials on structure, optical nanosensors for pharmaceutical detection, chemical nanosensors in pharmaceutical analysis, noble metal nanoparticles in electrochemical analysis of drugs, photo-electrochemica... nanosensors for drug analysis, molecularly imprinted polymer based nanosensors for pharmaceutical analysis, nanomaterials for drug delivery systems, nanomaterials enriched nucleic acid-based biosensors, nanosensors in biomarker detection, and nanomaterials-based enzyme biosensors for electrochemical applications.

  • Advances in Phytonanotechnology

    From Synthesis to Application
    • 1st Edition
    • Mansour Ghorbanpour + 1 more
    • English
    Advances in Phytonanotechnology: From Synthesis to Application guides readers through various applications of nanomaterials on plants by presenting the latest research related to nanotechnology and nanomaterials on plant systems. The book focuses on the effects of these applications on plant morphology, physiology, biochemistry, ecology and genetics. Sections cover the impact on plant yield, techniques, a review of positive and negative impacts, and an overview of current policies regarding the use of nanotechnology on plants. Additionally, the book offers insights into the appropriate application of nanoscience to plants and crops for improved outcome and an exploration of their bioavailability and toxicity in the environment.

  • Wilson Disease

    Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring
    • 1st Edition
    • Karl Heinz Weiss + 1 more
    • English
    Wilson Disease: Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring translates both clinical and experimental findings into a comprehensive approach for anyone involved in research and patient care. While the clinical variability of Wilson Disease poses a challenge from a diagnostic approach, the book uses the translational impact of new research findings to relate to new treatment concepts. Comprehensive chapters include common knowledge, guideline consensus statements, and discussions of clinical evidence. This is a must-have reference for researchers and clinicians in translational research.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 346
    • English
    International Review of Cell and Molecular Biology, Volume 346, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include the karyosphere (karyosome) and its peculiar structure of the oocyte nucleus, organoids as models of disease, lipid droplets as organelles, the dark side of apoptosis, interconnections between autophagy and secretion, and the regulation and function of intracellular pressure in cell biology.

  • Nanotechnology

    • 1st Edition
    • Volume 46
    • English
    Nanotechnology, Volume 46, the latest release in the Methods in Microbiology series, contains review articles on the application of nanotechnology in various fields of microbiology, including environmental microbiology, food microbiology and medical microbiology. Chapters in this new release include discussions on the Biosynthesis of Nanomaterials Utilizing Biomacromolecules, Nanotechnology in Medical Biology – Application of Nanodiagnostics in Infectious Diseases, Applications of Nanotechnology in Food Microbiology, Biosynthesis of Nanomaterials Utilizing Microorganisms, Nanotechnology in Medical Biology – Interaction of Pathogens and Nanostructured Surfaces, Biocompatible Polymers: Synthesis Methods, Surface Functionalization and its Biomedical Applications, and The Bacterial Flagellum.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 90
    • English
    Advances in Clinical Chemistry, Volume 90, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

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