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Elsevier

Books in Life sciences

  • Biological NMR Part A

    • 1st Edition
    • Volume 614
    • A.Joshua Wand
    • English
    Biological NMR, Part A, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs and micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, Structure determination and computer analysis, and much more.

  • The Auditory Brain and Age-Related Hearing Impairment

    • 1st Edition
    • Jos J. Eggermont
    • English
    The Auditory Brain and Age-Related Hearing Impairment provides an overview of the interaction between age-related hearing impairments and cognitive brain function. This monograph elucidates the techniques used in the connectome and other brain-network studies based on electrophysiological methods. Discussions of the manifestations of age-related hearing impairment, the causes of degradation of sound processing, compensatory changes in the human brain, and rehabilitation and intervention are included. There is currently a surge in content on aging and hearing loss, the benefits of hearing aids and implants, and the correlation between hearing loss, cognitive decline and early onset of dementia. Given the changing demographics, treatment of age-related hearing impairment need not just be bottom-up (i.e., by amplification and/or cochlear implantation), but also top-down by addressing the impact of the changing brain on communication. The role of age-related capacity for audio-visual integration and its role in assisting treatment have only recently been investigated, thus this area needs more attention.

  • The Orexin/Hypocretin System

    Functional Roles and Therapeutic Potential
    • 1st Edition
    • Jim R. Fadel + 1 more
    • English
    The Orexins/Hypocretins System: Functional Roles and Therapeutic Potential summarizes research on both the physiological functioning of orexins, their impact on homeostatic processes, and related disorders. The book encompasses the effects on appetite, sleep, substance abuse, cognition, and anxiety. Additionally, it examines new therapeutic approaches utilizing orexins, including utilization of orexin receptors for drug development. It is essential reading for neuroscience researchers interested in brain-behavior relationships, as well as psychiatrists, endocrinologists and pharmacologists.

  • Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

    • 1st Edition
    • Joel Faintuch + 1 more
    • English
    Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource. The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 1st Edition
    • Joao L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness.

  • Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain

    • 1st Edition
    • Michael Petrides
    • English
    Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain provides a comprehensive identification of the sulci and gyri of the human brain on a series of coronal sections of the average MNI brain and identifies the likely location of the cytoarchitectonic areas of the cerebral cortex. Presentation in MNI Stereotaxic Space enables the atlas to serve as a useful working tool for structural/functiona... neuroimagers attempting to identify the sulcus or gyrus and the likely cytoarchitectonic area within which a functional activation or a structural change has occurred. A brief introductory section discusses the history and current state of studies of the sulcal and gyral morphology and cytoarchitecture of the human cerebral cortex.

  • Production and Management of Beverages

    Volume 1. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Production and Management of Beverages, Volume One in the Science of Beverages series, introduces the broad world of beverage science, providing an overview of the emerging trends in the industry and the potential solutions to challenges such as sustainability and waste. Fundamental information on production and processing technologies, safety, quality control, and nutrition are covered for a wide range of beverage types, including both alcoholic and nonalcoholic beverages, fermented beverages, cocoa and other powder based beverages and more. This is an essential resource for food scientists, technologists, chemists, engineers, microbiologists and students entering into this field.

  • Processing and Sustainability of Beverages

    Volume 2: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Processing and Sustainability of Beverages, Volume Two in the Science of Beverages series, is a general reference of the current and future actions for a sustainable beverage industry. This resource takes a unique approach, combining processing with sustainability. Topics of note include waste treatment and management, environmental analysis for a sustainable beverage industry, and modern technologies for beverage processing to reduce contaminants and increase the quality. This book is essential to scientists, researchers and technologists in the beverages field, covering both alcoholic and nonalcoholic beverages.

  • The Eradication of Dracunculiasis (Guinea Worm Disease) in Nigeria

    An Eyewitness Account
    • 1st Edition
    • Luke Ekundayo Edungbola
    • English
    The Eradication of Dracunculiasis (Guinea Worm Disease) in Nigeria: An Eyewitness Account documents the process used to eradicate one of the most neglected public health challenges in Nigeria. The book's chapters discuss the need for well developed and implemented eradication strategies, the availability of human and material resources, and the collaboration that is necessary with international partners. In addition, sections highlight challenges, the benefits of perseverance, and the international support and multi-sectoral approach that is needed to tackle national problems. It demonstrates that other endemic tropical diseases and conditions can be eliminated or controlled if a similar approach is adopted.

  • Bioactive Compounds

    Health Benefits and Potential Applications
    • 1st Edition
    • Maira Rubi Segura Campos
    • English
    Bioactive Compounds: Health Benefits and Potential Applications provides information about different bioactive compounds including their sources, biological effects, health benefits and, potential applications which could contribute as alternatives in the prevention or treatment of multifactorial diseases for vulnerable population groups. Going beyond the basics to include discussion of bioaccessibility and the legislative aspects of marketing of bioactive compounds as nutraceuticals or food supplements, this book presents insights from a global perspective. Written for researchers, professors and graduate students, this book is sure to be a welcomed reference for all who work in food chemistry, new product development and nutritional science.

  • Imagining the Brain: Episodes in the History of Brain Research

    • 1st Edition
    • Volume 243
    • Chiara Ambrosio + 1 more
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Basic Fundamentals of Drug Delivery

    • 1st Edition
    • English
    Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation.

  • Cyanobacteria

    From Basic Science to Applications
    • 1st Edition
    • A.K. Mishra + 2 more
    • English
    Cyanobacteria constitute the most widely distributed group of photosynthetic prokaryotes found in almost all realms of the earth and play an important role in Earth’s nitrogen and carbon cycle. The gradual transformation from reducing atmosphere to oxidizing atmosphere was a turning point in the evolutionary history of the earth and made conditions for present life forms possible. Cyanobacteria: From Basic Science to Applications is the first reference volume that comprehensively discusses all aspects of cyanobacteria, including the diverse mechanisms of cyanobacteria for the advancement of cyanobacterial abilities, towards higher biofuel productivity, enhanced tolerance to environmental stress and bioactive compounds and potential for biofertilizers.

  • Biocontamination Control for Pharmaceuticals and Healthcare

    • 1st Edition
    • Tim Sandle
    • English
    Biocontamination Control for Pharmaceuticals and Healthcare outlines a biocontamination strategy that tracks bio-burden control and reduction at each transition in classified areas of a facility. This key part of controlling risk escalation can lead to the contamination of medicinal products, hence necessary tracking precautions are essential. Regulatory authorities have challenged pharmaceutical companies, healthcare providers, and those in manufacturing practice to adopt a holistic approach to contamination control. New technologies are needed to introduce barriers between personnel and the environment, and to provide a rapid and more accurate assessment of risk. This book offers guidance on building a complete biocontamination strategy.

  • Machine Learning in Bio-Signal Analysis and Diagnostic Imaging

    • 1st Edition
    • Nilanjan Dey + 3 more
    • English
    Machine Learning in Bio-Signal Analysis and Diagnostic Imaging presents original research on the advanced analysis and classification techniques of biomedical signals and images that cover both supervised and unsupervised machine learning models, standards, algorithms, and their applications, along with the difficulties and challenges faced by healthcare professionals in analyzing biomedical signals and diagnostic images. These intelligent recommender systems are designed based on machine learning, soft computing, computer vision, artificial intelligence and data mining techniques. Classification and clustering techniques, such as PCA, SVM, techniques, Naive Bayes, Neural Network, Decision trees, and Association Rule Mining are among the approaches presented. The design of high accuracy decision support systems assists and eases the job of healthcare practitioners and suits a variety of applications. Integrating Machine Learning (ML) technology with human visual psychometrics helps to meet the demands of radiologists in improving the efficiency and quality of diagnosis in dealing with unique and complex diseases in real time by reducing human errors and allowing fast and rigorous analysis. The book's target audience includes professors and students in biomedical engineering and medical schools, researchers and engineers.

  • Sustainable Food and Agriculture

    An Integrated Approach
    • 1st Edition
    • Clayton Campanhola + 1 more
    • English
    Sustainable Food and Agriculture: An Integrated Approach is the first book to look at the imminent threats to sustainable food security through a cross-sectoral lens. As the world faces food supply challenges posed by the declining growth rate of agricultural productivity, accelerated deterioration of quantity and quality of natural resources that underpin agricultural production, climate change, and hunger, poverty and malnutrition, a multi-faced understanding is key to identifying practical solutions. This book gives stakeholders a common vision, concept and methods that are based on proven and widely agreed strategies for continuous improvement in sustainability at different scales. While information on policies and technologies that would enhance productivity and sustainability of individual agricultural sectors is available to some extent, literature is practically devoid of information and experiences for countries and communities considering a comprehensive approach (cross-sectoral policies, strategies and technologies) to SFA. This book is the first effort to fill this gap, providing information on proven options for enhancing productivity, profitability, equity and environmental sustainability of individual sectors and, in addition, how to identify opportunities and actions for exploiting cross-sectoral synergies.

  • The Technology of Wafers and Waffles II

    Recipes, Product Development and Know-How
    • 1st Edition
    • Karl F. Tiefenbacher
    • English
    The Technology of Wafers and Waffles: Recipes, Product Development and Knowhow is the definitive reference book addressing new product development in wafers and waffles. As a companion manual to The Technology of Wafers and Waffles: Operational Aspects, it provides a varied selection of recipes for different types of wafers, waffles, and fillings. This book discusses flat and shaped wafers, ice cream cones, cups, wafer reels, wafer sticks, stroop waffles, and North American frozen waffles. A separate chapter focuses on recipe calculations for wafer and waffle batters, doughs, and fillings, which allows estimating output, cost, and main nutrient content. Finally, there is also an overview on the patent and food science literature on wafers and waffles in chronological order.

  • Enzymes of Energy Technology

    • 1st Edition
    • Volume 613
    • Fraser Armstrong
    • English
    Enzymes of Energy Technology, Volume 613 in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Chapters include Purification of fully active and crystallizable photosystem II from thermophilic cyanobacteria, Production and manipulation of [NiFeSe]-hydrogenase... for renewable hydrogen research, Hydrogen production by [FeFe]-hydrogenases, Production and properties of enzymes that activate and produce carbon monoxide, Recombinant [NiFe]-hydrogenases from E. coli, Working with nitrogenase, Oxygen--tolerant [NiFe]-hydrogenases, Cytoplasmic and Membrane Bound Hydrogenases from the hyperthermophile Pyrococcus furiosus, and more. Additional sections cover Enzymatic conversion of methane into useful chemicals, Production and investigations of trans-membrane electron transfer protein, Characterization of post-translational modifications in methyl-coenzyme M reductase in diverse methanogens by mass-spectrometry, Reductive activation of carbon dioxide by formate dehydrogenases, and Lytic polysaccharide monooxygenases in biofuel processing. 14. Production and manipulation of blue copper oxidases for technological applications Yasmina Mekmouche

  • The Chick Brain in Stereotaxic Coordinates and Alternate Stains

    Featuring Neuromeric Divisions and Mammalian Homologies
    • 2nd Edition
    • Luis Puelles + 4 more
    • English
    This atlas – and its accompanying text - is the most comprehensive work on avian neuroanatomy available so far. It identifies more than 900 hundred structures (versus ca. 250 in previous avian atlases), 180 of them for the first time. It correlates avian and mammalian neuroanatomy on the basis of homologies and applies mammalian terms to homologous avian structures. This is the first atlas that represents the fundamental histogenetic domains of the vertebrate neuroaxis on the basis of sound fate-mapping and gene expression data. This results in a substantial increase in accuracy of delineations. Developmental molecular biologists will find it easier to extrapolate early neural tube patterns into mature structures. The modern trend to shift avian neuroanatomical nomenclature toward mammalian terminology by reference to postulated homologies has been expanded to the entire brain, but is not yet complete. This creates a new standard for comparative cross-reference, which can also be applied to reptilian-mammalian comparisons.

  • Breath Analysis

    • 1st Edition
    • Giorgio Pennazza + 1 more
    • English
    Breath Analysis presents state-of-the-art research in this specialized field, also offering guidance on how best to design the technology and conduct analysis. The book primarily focuses on the diagnosis of lung cancer, asthma and Chronic Obstructive Pulmonary Diseases. The reliability, consistency and utility of the results from breath analysis depends on exhaled breath sampling procedures and tools, gas sensor array technology (sensing material and transducer), and finally, medical pertinence and interpretation. The book gives step-by-step procedures and discusses best practice solutions for problems in sample collection, sensor technology, clinical assessment, medical interpretation and data analysis. The book's primary audience would include biomedical engineers and medical doctors, but it is also useful for hospital technicians, hospital and biomedical SME leading figures, and those in PhD level Engineering and Medicine.

  • Senescence Signalling and Control in Plants

    • 1st Edition
    • Maryam Sarwat + 1 more
    • English
    Senescence Signalling and Control in Plants discusses the studies showing the importance of hormone action on developmental senescence. It shows the involvement of various signaling components (such as EIN2, LOX2) and transcription factors (such as oresara1 or ORE1) in controlling hormonal activity during senescence. Further, the involvement of various micro RNAs (miR164, miR319) in regulating leaf senescence are discussed. Through this book, the authors throw light on all the reverse and forward genetic approaches to reveal the role of various other phytohormones regulating plant senescence and the molecular mechanisms involved. Chapters on relevant topics are contributed by experts working in the area, making this a comprehensive treatise designed to provide an in-depth analysis on the subject matter.

  • Dog Behavior

    Modern Science and Our Canine Companions
    • 1st Edition
    • James C. Ha + 1 more
    • English
    Dog Behavior: Modern Science and Our Canine Companions provides readers with a better understanding of canine science, including evolutionary concepts, ethograms, brain structures and development, sensory perspectives, the science of emotions, social structure, and the natural history of the species. The book also analyzes relationships between humans and dogs and how the latter has evolved. Readers will find this to be an ideal resource for researchers and students in animal behavior, specifically focusing on dog behavior and human-canine relationships. In addition, veterinarians seeking further information on dog behavior and the social temperament of these companion animals will find this book to be informative.

  • Handbook of Biomechatronics

    • 1st Edition
    • Jacob Segil
    • English
    Handbook of Biomechatronics provides an introduction to biomechatronic design as well as in-depth explanations of some of the most exciting and ground-breaking biomechatronic devices in the world today. Edited by Dr. Jacob Segil and written by a team of biomechatronics experts, the work begins with broad topics concerning biomechatronic design and components, followed by more detailed discussions of specific biomechatronic devices spanning many disciplines. This book is structured into three main parts: biomechatronic design, biomechatronic components, and biomechatronic devices. The biomechatronic design chapter discusses the history of biomechatronics, conceptual design theory, biomechatronic design methods, and design tools. The next section discusses the technologies involved in the following components: sensors, actuators, and control systems. The biomechatronic devices chapters contains distinct examples of biomechatronic devices spanning visual prostheses to brain-machine interfaces. Each chapter presents the development of these biomechatronic devices followed by an in-depth discussion of the current state of the art

  • Laboratory Assessment of Vitamin Status

    • 1st Edition
    • Dominic J. Harrington
    • English
    Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of ‘Best Practice’ approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status.

  • High-Density Sequencing Applications in Microbial Molecular Genetics

    • 1st Edition
    • Volume 612
    • English
    High-Density Sequencing Applications in Microbial Molecular Genetics, Volume 612 in the Methods of Enzymology series provides the latest on the high-density sequencing of DNA and cDNA libraries and how they have revolutionized contemporary research in biology. Methods permitting tens of millions of sequence reads in a single experiment have paved the way to genome-wide studies that are contributing to our understanding of the complexity of living systems. Chapters in this updated volume include Characterizing the role of exoribonucleases in the control of microbial gene expression: Differential RNA seq., Conformational studies of bacterial chromosomes by high-throughput sequencing methods, Measuring mRNA degradation, and more. Addition sections cover Global recognition patterns of bacterial RNA-binding proteins, High-resolution profiling of NMD targets, and the Generation of a metagenomic 3C/Hi-C library of human gut microbiota, Genome-wide mapping of yeast retrotransposons integration target sites, Measuring protein synthesis rates, Finding unsuspected partners of small RNAs with new screening approaches, Use of multiplexed transcriptomics to define the relationship between promoter sequence and transcription output, RNA-based control of quorum sensing in Vibrio cholerae, amongst other highly regarded topics.

  • Cadmium Toxicity and Tolerance in Plants

    From Physiology to Remediation
    • 1st Edition
    • Mirza Hasanuzzaman + 2 more
    • English
    Cadmium Toxicity and Tolerance in Plants: From Physiology to Remediation presents a single research resource on the latest in cadmium toxicity and tolerance in plants. The book covers many important areas, including means of Cd reduction, from plant adaptation, including antioxidant defense, active excretion and chelation, to phytoextraction, rhizo filtration, phytodegradation, and much more. In addition, it explores important insights into the physiological and molecular mechanisms of Cd uptake and transport and presents options for improving resistance to Cd stresses. It will be ideal for both researchers and students working on cadmium pollution, plant responses and related fields of environmental contamination and toxicology.

  • Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders

    • 1st Edition
    • Lindsay M. Oberman + 1 more
    • English
    Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette’s Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback.

  • Epigenetics of Cancer Prevention

    • 1st Edition
    • Volume 8
    • Anupam Bishayee + 1 more
    • English
    Epigenetics of Cancer Prevention, Volume Ten is the first to look at epigenetics and chemoprevention together. Although there is numerous scientific data available on how epigenetics can lead to cancer and how chemoprevention can be beneficial in the treatment of, or improvement of quality of life, together they will set an advanced understanding for the reader in this upcoming field of chemoprevention influencing epigenetics. This book discusses molecular epigenetic targets of natural products, such as green tea polyphenols, curcumin and resveratrol, and organ specific epigenetic targets related to diverse types of cancer, for example prostate, colorectal, breast, lung and skin cancers. Additionally, it encompasses a discussion on research methods and limitations to study epigenetics and epigenomics of chemopreventive drugs and personalized cancer treatment with phytochemicals. The book is ideal for cancer researchers, health care professionals and all individuals who are interested in cancer prevention research and its clinical applications, especially in natural remedies.

  • Pharmacogenomics

    Challenges and Opportunities in Therapeutic Implementation
    • 2nd Edition
    • Yui-Wing Francis Lam + 1 more
    • English
    Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book also focuses on clinical areas with successful applications and important initiatives that have the ability to further advance the discipline. New chapters cover important topics such as pharmacogenomic data technologies, clinical testing strategies, cost-effectiveness, and pharmacogenomic education and practice guidelines. The importance of ethnicity is also discussed, which highlights phar,acogenomic diversity across Latin American populations.With chapters written by interdisciplinary experts and insights into the future direction of the field, this book is an indispensable resource for academic and industry scientists, graduate students and clinicians engaged in pharmacogenomics research and therapeutic implementation.

  • Case Studies in the Wine Industry

    • 1st Edition
    • Cristina Santini + 1 more
    • English
    Case Studies in the Wine Industry aims to close the gap between academic researchers and industry professionals through real world scenarios and field-based research. The book explores how consumer and sensory science has been implemented in the wine industry to achieve certain goals, including the rejuvenation of product image, the shaping of new market places, the achievement of market differentiation and geographical diffusion, the achievement of customer loyalty, and the promotion of traditional features of the product. There is an emerging demand from wine industry professionals and undergraduate and postgraduate students who attend business and agricultural studies courses who want to gain practical information through real cases and field-based research.

  • Nutrition in the Prevention and Treatment of Abdominal Obesity

    • 2nd Edition
    • Ronald Ross Watson
    • English
    Nutrition in the Prevention and Treatment of Abdominal Obesity, Second Edition focuses on the important role that exercise, dietary changes and foods play in promoting and reducing visceral fat. Nutritionists, dieticians and healthcare providers seeking to address the abdominal obesity epidemic will find this book to be a valuable resource in their long-term goal of preventing chronic diseases, especially heart, vascular and diabetic diseases. Chapters define a range of dietary approaches to reduce risk for the associated chronic diseases. In addition, discussions of the importance of dietary approaches to reduce abdominal obesity, along with clinical approaches, are discussed, including costs and risks.

  • The Human Challenge of Telemedicine

    Toward Time-sensitive and Person-centered Ethics in Home Telecare
    • 1st Edition
    • Philippe Bardy
    • English
    Telepatients using connected objects to collect time-sensitive data about their health are not neutral carriers of diagnosable symptoms. Patients are persons, or personal beings as well as co-carers, whose personal experience, history and know-how must be acknowledged in time-sensitive telecare practices. Such practices require a relational ethics, inspired by medical ethics and an ethics of virtues, focusing on vulnerability and emotional health, to oversee telecare good practices, define a new therapeutic alliance compliant with patients’ values, and reconcile the technical and human sides of telemedicine.

  • Neurosensory Disorders in Mild Traumatic Brain Injury

    • 1st Edition
    • Michael E. Hoffer + 1 more
    • English
    Mild traumatic Brain Injury (mTBI or Concussion) is an increasingly common public health issue in sports, military environments, and life in today’s active world. Despite a great deal of study and public attention to this disorder, knowledge about optimal diagnostic, prognostic, and treatment information remains lacking. Neurosensory symptoms have been shown to be the most frequent complications of mTBI in both the acute and chronic setting. Neurosensory Disorders in Mild Traumatic Brain Injury brings together both the basic science work as well as the clinical work in mTBI into one volume to provide a comprehensive examination of the neurosensory issues associated with this disorder. Coverage includes chapters on defining mild Traumatic Brain Injury, neurosensory consequences, neurosensory disorders in clinical practice, and diagnosis and treatment for neurosensory disorders in mTBI. This book is written for clinicians, researchers, residents and students in neurology and neuroscience.

  • Sports Neurology

    • 1st Edition
    • Volume 158
    • English
    Sports Neurology is designed to be a comprehensive overview of neurology within the context of sports medicine. This definitive text addresses the history of sports neurology, including its unique role within sports medicine, and provides a detailed assessment of central and peripheral nervous system injuries and illnesses in athletes. Sports Neurology is a critical companion for all sports medicine clinicians and for neurologists who manage athletes.

  • Balance, Gait, and Falls

    • 1st Edition
    • Volume 159
    • English
    Balance, Gait, and Falls, Volume 159 presents the latest information on sensorimotor anatomy, sensory integration, gravity and verticality, standing balance, balance perturbations, voluntary stepping and gait initiation, gait and gait adaptability, disorders of balance and gait that result from aging and neurological diseases. The book provides a brief overview of age-related changes in the structure and function of sensorimotor and central processes, with sections specifically devoted to Parkinson’s disease, parkinsonism, cerebellar ataxia, stroke, corticobasal degeneration, multiple sclerosis, Huntington’s disease, dystonia, tremor, Alzheimer’s disease, frontotemporal dementia, cerebral palsy, polio, motor neuron disease, brainstem lesions, spinal lesions, peripheral nerve disease, and psychogenic conditions. Diseases covered have a common structure comprising background and epidemiology, pathology, balance disorders, gait disorders, falls, therapies (including fall prevention), and future directions.

  • Translational Inflammation

    • 1st Edition
    • English
    Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology.

  • Leveraging Biomedical and Healthcare Data

    Semantics, Analytics and Knowledge
    • 1st Edition
    • Firas Kobeissy + 3 more
    • English
    Leveraging Biomedical and Healthcare Data: Semantics, Analytics and Knowledge provides an overview of the approaches used in semantic systems biology, introduces novel areas of its application, and describes step-wise protocols for transforming heterogeneous data into useful knowledge that can influence healthcare and biomedical research. Given the astronomical increase in the number of published reports, papers, and datasets over the last few decades, the ability to curate this data has become a new field of biomedical and healthcare research. This book discusses big data text-based mining to better understand the molecular architecture of diseases and to guide health care decision. It will be a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in understanding more about how to process and apply great amounts of data to improve their research.

  • Clinical Pharmacy Education, Practice and Research

    Clinical Pharmacy, Drug Information, Pharmacovigilance, Pharmacoeconomics and Clinical Research
    • 1st Edition
    • Dixon Thomas
    • English
    Clinical Pharmacy Education, Practice and Research offers readers a solid foundation in clinical pharmacy and related sciences through contributions by 83 leading experts in the field from 25 countries. This book stresses educational approaches that empower pharmacists with patient care and research competencies. The learning objectives and writing style of the book focus on clarifying the concepts comprehensively for a pharmacist, from regular patient counseling to pharmacogenomics practice. It covers all interesting topics a pharmacist should know. This book serves as a basis to standardize and coordinate learning to practice, explaining basics and using self-learning strategies through online resources or other advanced texts. With an educational approach, it guides pharmacy students and pharmacists to learn quickly and apply. Clinical Pharmacy Education, Practice and Research provides an essential foundation for pharmacy students and pharmacists globally.

  • Neurology of Pregnancy, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 37-1
    • Mary Angel O'Neal
    • English
    This issue of Neurologic Clinics, guest edited by Dr. Mary Angela O’Neal, with consulting editor Randolph W. Evans, will focus on Neurology of Pregnancy. Topics include, but are not limited to, Neuro-Ophthalmologic... Disorders in Pregnancy, Management of Demyelinating Disorders in Pregnancy, Postpartum Neuropathies, Management of Myasthenia Gravis during Pregnancy, Headache in Pregnancy and Postpartum, Epilepsy, Pituitary Disorders, Stroke, Imaging Considerations in Pregnancy, and Connective Tissue Disorders in Pregnancy.

  • Organic Farming

    Global Perspectives and Methods
    • 1st Edition
    • Sarath Chandran + 2 more
    • English
    Organic Farming: Global Perspectives and Methods explores the core definition and concepts of organic farming in sustainability, its influence on the ecosystem, the significance of seed, soil management, water management, weed management, the significance of microorganisms in organic farming, livestock management, and waste management. The book provides readers with a basic idea of organic farming that presents advancements in the field and insights on the future. Written by a team of global experts, and with the aim of providing a current understanding of organic farming, this resource is valuable for researchers, graduate students, and post-doctoral fellows from academia and research institutions.

  • Connected Healthcare for the Citizen

    • 1st Edition
    • Robert Picard
    • English
    Value of Connected Things for Healthcare is based on feedback from members of the LLSA Forum, patients, healthcare professionals, Living Labs, industrialists, researchers and institutional actors confronted with the design, development, implementation and use of these types of tools that penetrate health and communicate data. The term connected object refers to devices that continuously collect data through these objects, providing the state of health of people wherever they are and whatever they do. These objects allow clinical researchers to study new phenomena that have hitherto escaped observations in institutions. However, the mobilization of these technologies in this context poses technical questions because the requirements of a remote, continuous operation are high. What is termed connected health emphasizes the human dimension of the subject, i.e., citizens, patients, health professionals, territorial communities, professional networks, institutions and associations. The questions of who benefits and ethical considerations are paramount to this discussion.

  • Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

    Models in Discovery and Translation
    • 2nd Edition
    • Gerard Socie + 2 more
    • English
    Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemi... effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts.

  • Microfluidics in Cell Biology Part C: Microfluidics for Cellular and Subcellular Analysis

    • 1st Edition
    • Volume 148
    • English
    Microfluidics in Cell Biology Part C, Volume 148, a new release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various multi-cellular models, including microfluidics in cell monolayers/spheroids... microfluidics in organ on chips, and microfluidics in model organisms. Specific chapters discuss collective migration in microtubes, leukocyte adhesion dynamics on endothelial monolayers under flow, constrained spheroid for perfusion culture, cells in droplet arrays, heart on chips, kidney on chips, liver on chips, and more.

  • Cognitive Prosthethics

    • 1st Edition
    • Maxime Derian
    • English
    Computerized machines can be found in many forms and all around us – in our pockets, and even sometimes in our body. For many of us, they are now essential elements of everyday life. When it comes to smartphones, connected objects, medical digital devices and e-health, these digital tools have proliferated in our environment, continually transforming our modes of social organization. They act as prostheses and orthotics that “enhance” our cognitive capacities and influence our inherent behaviors. Are digital tools that perpetually envelop the body and the spirit able to overwhelm the social order? Could our cognitive prosthetics lead to permanent, radical change to our society, which could become similar to a hive? This book explores this reflection, which is at the center of social research on digital tools.

  • Imaging in Movement Disorders: Imaging Applications in Non-Parkinsonian and Other Movement Disorders

    • 1st Edition
    • Volume 143
    • Marios Politis
    • English
    Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics.

  • Psychedelic Neuroscience

    • 1st Edition
    • Volume 242
    • Tanya Calvey
    • English
    We are in the midst of what is being called the ‘psychedelic renaissance’ with growing interest into how psychedelics alter consciousness, brain function and brain connectivity. The acute, often profound, effects of the psychedelic experience can induce lasting improvements in mental health demonstrating that chemistry forms the basis of mystical experience, consciousness and mental wellbeing.

  • Plant Epigenetics Coming of Age for Breeding Applications

    • 1st Edition
    • Volume 88
    • English
    Epigenetics and Breeding, Volume 88, the latest release in the Advances in Botanical Research series, brings together the experiences and critical information teachers, researchers and managers must consider from both scientific and legal points-of-view as they relate to biotechnology. New chapters in this updated volume include sections on Epigenetic Mechanisms in Plants, Epigenomic Diversity and Applications to Breeding, Epigenetics in Breeding, EpiRILs: Lessons from Arabidopsis, Transposable Elements as a Tool for Plant Improvement, Epigenome Editing, Epigenetics and Grafting, Sexual and Non-sexual reproduction, Epigenetics in Cereals, and more.

  • Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

    • 1st Edition
    • Volume 4
    • English
    Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new sensitizing agents to their research in clinical practice and in trials.

  • Neuroergonomics

    The Brain at Work and in Everyday Life
    • 1st Edition
    • Hasan Ayaz + 1 more
    • English
    Neuroergonomics: The Brain at Work and in Everyday Life details the methodologies that are useful for keeping an ideal human-machine system up-to-date, along with information on how to prevent potential overload and minimize errors. It discusses neural measures and the proper methods and technologies to maximize performance, thus providing a resource for neuroscientists who want to learn more about the technologies and real-time tools that can help them assess cognitive and motivational states of human operators and close the loop for advanced human-machine interaction. With the advent of new and improved tools that allow monitoring of brain activity in the field and better identification of neurophysiological markers that can index impending overload or fatigue, this book is a timely resource on the topic.

  • Advanced Nanomaterials for Membrane Synthesis and Its Applications

    • 1st Edition
    • Woei Jye Lau + 3 more
    • English
    Advanced Nanomaterials for Membrane Synthesis and Its Applications provides the academic and industrial communities the most up-to-date information on the latest trends in membrane nanomaterials and membrane nanotechnology used in wastewater treatment, environmental technology and energy. The rapid advances in nanomaterials and nanotechnology development over the past decade have resulted in significant growth of the membrane business for various industrial processes, particularly in nanotechnology-based membrane processes. While membrane technology is increasingly being used for liquid and gas separations, it has great potential in a variety of additional applications. As the worldwide academic community has a strong interest in advanced membrane processes, particularly membrane nanotechnology for specific separations, this book provides a timely update on the topic.

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