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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • The Kinin System

      • 1st Edition
      • April 1, 1997
      • Stephen G. Farmer
      • English
      • Paperback
        9 7 8 0 1 2 3 8 8 4 6 3 3
      • eBook
        9 7 8 0 0 8 0 5 4 2 5 2 2
      Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:"A delicious masterpiece."--Chef'... DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases.

    • The Eye's Aqueous Humor: From Secretion to Glaucoma

      • 1st Edition
      • Volume 45
      • February 9, 1997
      • English
      • Paperback
        9 7 8 0 1 2 4 0 1 5 3 4 0
      • eBook
        9 7 8 0 0 8 0 5 8 5 1 6 1
      This volume presents a basic consensus of how the aqueous humor is formed and exits through the trabecular meshwork and canal of Schlemm. It presents a timely update to current knowledge of the molecular transport mechanisms which underlie aqueous humor dynamics. In addition, it provides a concise description of the clinical approaches used for assessing these basic transport processes. The book emphasizes the phenomenon of the diurnal rhythm of aqueous humor formation, from both the clinical and molecular points of view. This phenomenon provides the major indication that aqueous humor secretion is regulated.

    • International Review of Neurobiology

      • 1st Edition
      • Volume 39
      • December 2, 1996
      • English
      • Paperback
        9 7 8 0 1 2 4 1 5 7 3 8 5
      • eBook
        9 7 8 0 0 8 0 8 5 7 7 3 2
      Since 1959, International Review of Neurobiology has been a well known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.

    • Drugs and Human Lactation

      • 2nd Edition
      • November 19, 1996
      • A. Astrup-Jensen + 12 more
      • P.N. Bennett
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 0 7 3 7
      • eBook
        9 7 8 0 0 8 0 5 3 0 5 5 0
      Now in its second edition, Drugs and Human Lactation is a comprehensive guide to the content and consequences of xenobiotics and micronutrients in human milk, and remains by far the most thorough and extensive work available on this subject. The excellent methodology used for the compilation of the 1st edition has been retained.It begins with an outline of the processes by which substances enter milk during its formation, the effects of drugs on the milk production process, the main determinants of drug excretion into milk and their disposition in the child. There follows an analysis of current data on 234 individual drugs, describing the extent of their passage into human milk, and assessing the risk to the suckling infant. Vitamins and essential trace elements, and radiopharmaceuticals are similarly reviewed. Also included is an account of the factors that influence the passage of environmental and occupational chemicals into milk. The result is a complete overview of what is known and proven, with clear pointers to matters which require further study, and brings the various subject areas up to date. Risks, uncertainties and false alarms which exist have been defined in such a way that they can be avoided.Once again, Drugs and Human Lactation provides a comprehensive guide to the content and consequences of substances in milk. The volume will provide a rational basis for making therapeutic decisions in women who seek to breast-feed.Reproduc... Immunology on the first edition: ...a superbly written compendium of reliable information and sensible conclusions and recommendations.

    • In Vitro Methods in Pharmaceutical Research

      • 1st Edition
      • October 4, 1996
      • Jose V. Castell + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 1 6 3 3 9 0 5
      • eBook
        9 7 8 0 0 8 0 5 3 4 6 0 2
      In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies.

    • Advances in Pharmacology

      • 1st Edition
      • Volume 37
      • September 30, 1996
      • English
      • Paperback
        9 7 8 0 1 2 3 9 9 3 6 4 9
      • Hardback
        9 7 8 0 1 2 0 3 2 9 3 8 0
      • eBook
        9 7 8 0 0 8 0 5 8 1 2 9 3
      Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

    • Phosphodiesterase Inhibitors

      • 1st Edition
      • August 16, 1996
      • English
      • Hardback
        9 7 8 0 1 2 2 1 0 7 2 0 7
      • eBook
        9 7 8 0 0 8 0 5 3 8 8 1 5
      Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting.

    • Neural Networks in QSAR and Drug Design

      • 1st Edition
      • August 9, 1996
      • James Devillers
      • English
      • Paperback
        9 7 8 0 1 2 3 8 8 4 5 9 6
      • eBook
        9 7 8 0 0 8 0 5 3 7 3 8 2
      Comprehensive and impeccably edited, Neural Networks in QSAR and Drug Design is the first book to present an all-inclusive coverage of the topic. The book provides a practice-oriented introduction to the different neural network paradigms, allowing the reader to easily understand and reproduce the results demonstrated. Numerous examples are detailed, demonstrating a variety of applications to QSAR and drug design.The contributors include some of the most distinguished names in the field, and the book provides an exhaustive bibliography, guiding readers to all the literature related to a particular type of application or neural network paradigm. The extensive index acts as a guide to the book, and makes retrieving information from chapters an easy task. A further research aid is a list of software with indications of availablility and price, as well as the editors scale rating the ease of use and interest/price ratio of each software package. The presentation of new, powerful tools for modeling molecular properties and the inclusion of many important neural network paradigms, coupled with extensive reference aids, makes Neural Networks in QSAR and Drug Design an essential reference source for those on the frontiers of this field.

    • Advances in DNA Sequence-Specific Agents

      • 1st Edition
      • Volume 2
      • July 9, 1996
      • J.B. Chaires
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 3 9 3 6
      • Hardback
        9 7 8 1 5 5 9 3 8 1 6 6 6
      • eBook
        9 7 8 0 0 8 0 5 2 6 1 4 0
      DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molec... interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of Advances in DNA Sequence Specific Agents. As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA.This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.

    • Advances in Drug Research

      • 1st Edition
      • Volume 28
      • July 2, 1996
      • English
      • Hardback
        9 7 8 0 1 2 0 1 3 3 2 8 4
      • eBook
        9 7 8 0 0 8 0 5 2 6 7 1 3
      This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets.

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