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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

    • Handbook of Neuroemergency Clinical Trials

      • 1st Edition
      • December 15, 2005
      • Wayne M. Alves + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 6 4 8 0 8 2 5
      • eBook
        9 7 8 0 0 8 0 4 5 4 3 5 1
      During the 1990’s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were “tested,” and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical area of unmet medical need. It represents a compendium of information gained from over 20 years of clinical trial experience in areas of acute neurology and neurosurgery. From the knowledge of clinical assessment using standardized tools, to the intricate design of difficult hyper-acute neuroemergencies trials, the reader will benefit from the authors’ perspectives.
    • Novel Anticancer Agents

      • 1st Edition
      • December 13, 2005
      • Alex A. Adjei + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 0 8 8 5 6 1 9
      • eBook
        9 7 8 0 0 8 0 5 3 7 7 5 7
      Novel Anticancer Agents offers pertinent basic science information on strategies used for the rational design and discovery of novel anticancer agents, and, in addition, translational studies involving clinical trial design and execution with these novel, mostly cytostatic agents. This book covers basic science strategies that are being used in drug discovery and preclinical evaluation focused on novel molecular targets, as well as clinical trial methodology including clinical pharmacokinetics and imaging to address issues of efficacy evaluation of the new, relatively non-cytotoxic anticancer agents. At present, there is no book that provides such an integration of basic and clinical studies of novel anticancer agents, covering both drug discovery and translational research extensively.
    • Encyclopedia of Heart Diseases

      • 1st Edition
      • December 5, 2005
      • M. Gabriel Khan
      • English
      • Hardback
        9 7 8 0 1 2 4 0 6 0 6 1 6
      • eBook
        9 7 8 0 0 8 0 4 5 4 8 1 8
      The Encyclopedia of Heart Diseases is an accurate and reliable source of in-depth information on the diseases that kill more than 12 million individuals worldwide each year. In fact, cardiovascular diseases are more prevalent than the combined incidence of all forms of cancer, diabetes, asthma and leukemia. In one volume, this Encylopedia thoroughly covers these ailments and also includes in-depth analysis of less common and rare heart conditions to round out the volume's scope. Researchers, clinicians, and students alike will all find this resource an invaluable tool for quick reference before approaching the primary literature.
    • Side Effects of Drugs Annual

      • 1st Edition
      • Volume 28
      • November 29, 2005
      • Jeffrey K. Aronson
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 2 8 6 1
      • Paperback
        9 7 8 0 4 4 4 5 1 5 7 1 1
      • eBook
        9 7 8 0 0 8 0 4 5 9 5 0 9
      Volume 28 in the series of Side Effects of Drugs Annuals (http://www.elsevier... continues to serve its primary goal: to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has reviewed new data and trends by selecting from the year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is unproven or misleading. The use of the book is enhanced by separate indexes, allowing the reader to access the text via drug name, adverse effect, or drug interaction. The current annual includes an essay by the editor, Dr Jeffrey Aronson, entitled 'Classifying Drug Adverse Reactions in the 21st Century.' In it he describes how the modern approach to classifying adverse drug reactions takes into account the dose that causes the reaction, the time-course of the reaction, and the susceptibility factors that increase the individual patient's risk, and shows how this analysis can facilitate regulatory decision making.
    • Annual Reports in Medicinal Chemistry

      • 1st Edition
      • Volume 39
      • December 15, 2004
      • Annette M. Doherty
      • English
      • Paperback
        9 7 8 0 1 2 0 4 0 5 3 9 8
      • eBook
        9 7 8 0 0 8 0 4 7 1 9 7 6
      Annual Reports in Medicinal Chemistry continues to focus on providing timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design.
    • Roles of Vasopressin and Oxytocin in Memory Processing

      • 1st Edition
      • Volume 50
      • August 30, 2004
      • Barbara McEwen
      • English
      • eBook
        9 7 8 0 0 8 0 5 2 4 5 1 1
      The Roles of Vasopressin and Oxytocin in Memory Processing reviews research progress in a subfield of Behavioral Pharmacology concerned with vasopressin’s (VP’s) and oxytocin (OT’s) roles in memory processing (MP). As hormones, VP is well-known for its pressor and antidiuretic action, and OT for its contribution to parturition and nursing. As neurotransmitters, they participate in a wide variety of self- and species-preserving functions expressed at psychological, physiological and behavioral levels. Advances in Pharmacology is available online on ScienceDirect — full-text online of volumes 48 onwards. Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elsevier’s extensive researcher network. For more information about the Elsevier Book Series on ScienceDirect Program, please visit:http://www.inf...
    • Vitamins and Hormones

      • 1st Edition
      • Volume 69
      • July 6, 2004
      • Gerald Litwack
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 2 2 7 8
      • eBook
        9 7 8 0 0 8 0 5 2 2 8 9 0
      First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.
    • Profiles of Drug Substances, Excipients and Related Methodology

      • 1st Edition
      • Volume 30
      • December 19, 2003
      • English
      • Paperback
        9 7 8 0 1 2 4 0 1 5 4 3 2
      • eBook
        9 7 8 0 0 8 0 5 2 2 6 3 0
      Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic.The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodologoy related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.
    • The Lung

      • 1st Edition
      • November 21, 2003
      • Kent Pinkerton + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 1 7 0 7
      • eBook
        9 7 8 0 0 8 0 4 8 1 3 5 7
      This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of some major lung diseases affecting infants and children. The book also deals with how the lung changes with age, and how the process of lung aging can be affected by the environment.
    • Side Effects of Drugs Annual

      • 1st Edition
      • Volume 26
      • August 22, 2003
      • English
      • eBook
        9 7 8 0 0 8 0 5 2 2 8 0 7
      The Side Effects of Drugs Annual was first published in 1977. It has been published continuously since then, as a yearly update to the encyclopaedic volume Meyler's Side Effects of Drugs. Each new Annual provides clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists have contributed to the Annuals by selecting critically from each year's publications all that is truly new and informative, by critically interpreting it, and by pointing out whatever is misleading. The use of the book is enhanced by separate indexes, allowing the reader to enter the text via the drug name, adverse effect, or drug interaction.Special features of the Annuals are the Side Effects of Drugs Essay, usually written by a guest author, and the special reviews: short articles, within the different chapters, that give extra attention to topics of current interest.The Essay in Annual 26 is entitled 'How safe is cannabis?' (by Professor L.L. Iversen) and there is a Historical Essay entitled 'From thalidomide to pharmacovigilance: a personal account' (by Professor D.J. Finney).The special reviews in this volume include, among others: The cognitive effects of Ecstasy Antipsychotic drugs and weight gain Vigabatrin-related visual abnormalities Managing the adverse effects of morphine The cardiotoxic effects of antihistamines Inhaled corticosteroids and growth inhibition in children Bioterrorism and its prevention through immunization