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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 26
      • September 22, 2011
      • English
      • eBook
        9 7 8 0 0 8 0 8 6 2 7 4 3
      There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

    • Strategy and Statistics in Clinical Trials

      • 1st Edition
      • June 26, 2011
      • Joseph Tal
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 9 0 9 8
      • eBook
        9 7 8 0 1 2 3 8 6 9 9 2 0
      Strategy and Statistics in Clinical Trials deals with the research processes and the role of statistics in these processes. The book offers real-life case studies and provides a practical, how to guide to biomedical R&D. It describes the statistical building blocks and concepts of clinical trials and promotes effective cooperation between statisticians and important other parties. The discussion is organized around 15 chapters. After providing an overview of clinical development and statistics, the book explores questions when planning clinical trials, along with the attributes of medical products. It then explains how to set research objectives and goes on to consider statistical thinking, estimation, testing procedures, and statistical significance, explanation and prediction. The rest of the book focuses on exploratory and confirmatory clinical trials; hypothesis testing and multiplicity; elements of clinical trial design; choosing trial endpoints; and determination of sample size. This book is for all individuals engaged in clinical research who are interested in a better understanding of statistics, including professional clinical researchers, professors, physicians, and researchers in laboratory. It will also be of interest to corporate and government laboratories, clinical research nurses, members of the allied health professions, and post-doctoral and graduate students.

    • GABAb Receptor Pharmacology: A Tribute to Norman Bowery

      • 1st Edition
      • Volume 58
      • August 4, 2010
      • English
      • Hardback
        9 7 8 0 1 2 3 7 8 6 4 7 0
      • eBook
        9 7 8 0 1 2 3 7 8 6 4 8 7
      This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse. The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular.

    • Cardiovascular Pharmacology: Endothelial Control

      • 1st Edition
      • Volume 60
      • December 7, 2010
      • English
      • Hardback
        9 7 8 0 1 2 3 8 5 0 6 1 4
      • eBook
        9 7 8 0 1 2 3 8 5 0 6 2 1
      Cardiovascular disease remains a major cause of death and disability in developed countries and, increasingly so, in the developing world. Presented in this volume of Advances in Pharmacology are some of the most promising possibilities for treating large numbers of individuals afflicted with these conditions.

    • Insect Pharmacology

      • 1st Edition
      • May 28, 2010
      • Lawrence I. Gilbert + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 8 1 4 4 7 0
      • eBook
        9 7 8 0 1 2 3 8 1 4 4 8 7
      The publication of the extensive 7-volume work Comprehensive Molecular Insect Science provided library customers and their end-users with a complete reference encompassing important developments and achievements in modern insect science, including reviews on the ecdysone receptor, lipocalins, and bacterial toxins. One of the most popular areas in entomology is pharmacology, and this derivative work, Insect Pharmacology, taps into a previously unapproached market – the end user who desires to purchase a comprehensive yet affordable work on important aspects of this topic. Contents will include timeless articles covering sodium channels, spider toxins and their potential for insect control, insect transformation for use in control, amino acid and neurotransmitter transporters, and more. New summaries for each chapter will give an overview of developments in the related article since its original publication.

    • Side Effects of Drugs Annual

      • 1st Edition
      • Volume 32
      • November 18, 2010
      • Jeffrey K. Aronson
      • English
      • Hardback
        9 7 8 0 4 4 4 5 3 5 5 0 4
      • eBook
        9 7 8 0 4 4 4 5 3 5 5 1 1
      The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has contributed to the informative, by critically interpreting it, and by pointing to whatever is misleading.

    • Systemic Lupus Erythematosus

      • 5th Edition
      • October 29, 2010
      • Robert G. Lahita + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 9 9 4 9
      • eBook
        9 7 8 0 0 8 0 9 6 1 7 1 2
      Systemic lupus erythematosus (S.L.E.), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness, or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment is the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, anti-malarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, similar to those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well regarded reference which combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries.

Related subjects

Biochemical pharmacology

Cardiovascular pharmacology

Clinical pharmacology therapeutics

Clinical trials

Drug adverse reactions and interactions

Endocrine exocrine pharmacology

Ethnopharmacology

Gastrointestinal pharmacology

Immunopharmacology pharmacology

Molecular pharmacology

Neoplastic cancer pharmacology

Pharmacokinetics pharmacodynamics

Pharmacology general

Principles of pharmacology

Psychoneuropharmacology

Pulmonary pharmacology

Renal and electrolyte pharmacology