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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Medicinal Natural Products: A Disease-Focused Approach

    • 1st Edition
    • Volume 55
    • September 21, 2020
    • English
    Medicinal Natural Products: A Disease-Focused Approach, Volume 55 in the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition, with chapters in this new release covering Medicinal Natural Products – An Introduction, Anticancer Natural Products, Antimicrobial Natural Products, Antimalarial and Antiparasitic Natural Products, Anti-inflammatory Natural Products, Neuroprotective Natural Products, Hepatoprotective Natural Products, Nephroprotective Natural Products, Cancer Chemopreventive Natural Products, Antipsoriatic Natural Products, Medicinal Natural Products in Osteoporosis, Antidiabetic Natural Products, Anti-obesity Natural Products, and much more.
  • Quadruplex Nucleic Acids As Targets For Medicinal Chemistry

    • 1st Edition
    • Volume 54
    • August 25, 2020
    • English
    The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-us... regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.
  • Rapid Acting Antidepressants

    • 1st Edition
    • Volume 89
    • June 26, 2020
    • English
    The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.
  • Nanotechnology Based Approaches for Tuberculosis Treatment

    • 1st Edition
    • June 10, 2020
    • Prashant Kesharwani
    • English
    Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis.
  • Drug Safety in Developing Countries

    Achievements and Challenges
    • 1st Edition
    • June 3, 2020
    • Yaser Mohammed Al-Worafi
    • English
    Drug Safety in Developing Countries: Achievements and Challenges provides comprehensive information on drug safety issues in developing countries. Drug safety practice in developing countries varies substantially from country to country. This can lead to a rise in adverse reactions and a lack of reporting can exasperate the situation and lead to negative medical outcomes. This book documents the history and development of drug safety systems, pharmacovigilance centers and activities in developing countries, describing their current situation and achievements of drug safety practice. Further, using extensive case studies, the book addresses the challenges of drug safety in developing countries.
  • From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors

    • 1st Edition
    • Volume 88
    • May 8, 2020
    • English
    From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.
  • Combination Therapy Against Multidrug Resistance

    • 1st Edition
    • April 30, 2020
    • Mohmmad Younus Wani + 1 more
    • English
    Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant
  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 59
    • April 30, 2020
    • David R. Witty + 1 more
    • English
    Progress in Medicinal Chemistry, Volume 59, provides a review of eclectic developments in medicinal G139 chemistry. Each chapter is written by an international board of authors, with this release focusing on Small Molecules - Giant Leaps for Immuno-Oncology, Reviewing P2X7, Reviewing ASK1, and Reviewing DNA-encoded libraries.
  • Practical Paediatric Prescribing

    How to Prescribe the Most Common Drugs
    • 1st Edition
    • April 16, 2020
    • Will Carroll + 4 more
    • English
    Prescribing for children is problematic. Children are not small adults in terms of their physiology, and they cannot be subjects in clinical trials. This makes prescribing for them something of an art and a daunting one at that for trainees. Will Carroll (co-editor of the Illustrated Textbook of Paediatrics amongst other titles for paediatrics trainees) with a team of fellow paediatricians and a hospital pharmacist have sought to demystify prescribing for children. The team has identified what from their experience are the most common drugs prescribed to children and have addressed each one, adding detail about how each medicine works. Each chapter follows the ABCDE structure covering Absorption, Biological effects, Clearance, Dosing and side Effects in children. This book is a succinct, portable reference, modelled closely on Hitchings et al.: The Top 100 Drugs.
  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 45
    • March 10, 2020
    • Harry G. Brittain
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. The series encompasses review articles, with this release focusing on Azilsartan Medoxomil, Piroxicam, Carbetapentane Citrate, Emtricitabine, Etrlotinib, Isotretinoin and Meloxicam.