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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • Considering the Patient in Pediatric Drug Development

      • 1st Edition
      • November 19, 2020
      • Klaus Rose
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 8 8 8 2
      • eBook
        9 7 8 0 1 2 8 2 4 2 0 5 6
      Considering the Patient in Pediatric Drug Development: How Good Intentions Turned into Harm addresses a fundamental challenge in drug development and healthcare for young patients. In clinical trials and clinical practice, the term "children" is used ambiguously to confer physiological characteristics to a chronological age limit, which in reality does not exist. This book outlines why the United States (US) and European Union's (EU) regulatory authorities, pediatric academia, and the pharmaceutical industry demand, support and perform pediatric drug studies, along with the key flaws of this demand that blurs the different administrative and physiological meanings of the term "child." In addition, the book covers why most pediatric regulatory studies lack medical sense and many even harm young patients and the conflicts of interest behind pediatric drug studies. It includes relevant information about the maturation of the human body regarding absorption, distribution, metabolism and excretion of food and drugs as well as key differences between newborns, infants, older children and adolescents.

    • Innovation in Clinical Trial Methodologies

      • 1st Edition
      • November 1, 2020
      • Peter Schueler
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 4 9 0 6
      • eBook
        9 7 8 0 3 2 3 8 6 0 0 6 2
      Innovation in Clinical Trial Methodologies: Lessons Learned during the Corona Pandemic presents a selection of updated chapters from Re-Engineering Clinical Trials that feature innovative options and methods in clinical trials. The Coronavirus pandemic is an accelerator for digitalization in many industries, including clinical trials. This book considers best practices, alternative study concepts requiring fewer patients, studies with less patient interaction, the design of "virtualized" protocols, and moving from data to decisions. This book will be helpful to pharmacologists, physicians and clinical researchers involved in the process of clinical development and clinical trial design.

    • From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors

      • 1st Edition
      • Volume 88
      • May 8, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 1 8 7 9
      • eBook
        9 7 8 0 1 2 8 2 0 1 8 8 6
      From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.

    • Profiles of Drug Substances, Excipients, and Related Methodology

      • 1st Edition
      • Volume 45
      • March 10, 2020
      • Harry G. Brittain
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 3 2 3 1
      • eBook
        9 7 8 0 1 2 8 2 0 3 2 4 8
      Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. The series encompasses review articles, with this release focusing on Azilsartan Medoxomil, Piroxicam, Carbetapentane Citrate, Emtricitabine, Etrlotinib, Isotretinoin and Meloxicam.

    • Drug Delivery Devices and Therapeutic Systems

      • 1st Edition
      • November 7, 2020
      • Eric Chappel
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 8 3 8 4
      • eBook
        9 7 8 0 1 2 8 1 9 8 3 9 1
      Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.

    • Rapid Acting Antidepressants

      • 1st Edition
      • Volume 89
      • June 26, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 1 8 9 3
      • eBook
        9 7 8 0 1 2 8 2 0 1 9 0 9
      The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.

    • Naturally Occurring Chemicals against Alzheimer’s Disease

      • 1st Edition
      • November 19, 2020
      • Tarun Belwal + 4 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 2 1 2 2
      • eBook
        9 7 8 0 1 2 8 1 9 2 1 3 9
      Naturally Occurring Chemicals against Alzheimer’s Disease offers a detailed discussion on the roles, molecular mechanisms, structural activity relationships, toxicology and clinical data on phytochemicals in relation to Alzheimer’s disease. The book examines the available phytochemicals and plants that are potentially effective, also determining the role and molecular targets of these phytochemicals in combating AD. This comprehensive resource will be helpful to researchers who are working on herbal drugs on AD, phytochemistry, pharmacology, toxicology, clinical trials, neuroscience and advancement in formulations.

    • Quadruplex Nucleic Acids As Targets For Medicinal Chemistry

      • 1st Edition
      • Volume 54
      • August 25, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 0 1 7 8
      • eBook
        9 7 8 0 1 2 8 2 1 0 1 8 5
      The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-us... regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.

    • Medicinal Plants in Asia and Pacific for Parasitic Infections

      • 1st Edition
      • October 20, 2020
      • Christophe Wiart
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 8 1 1 0
      • eBook
        9 7 8 0 1 2 8 1 6 8 1 2 7
      Medicinal Plants in Asia and Pacific for Parasitic Infections: Botany, Ethnopharmacology, Molecular Basis, and Future Prospect offers an in-depth view into antiprotozoal pharmacology of natural products from medicinal plants in Asia with an emphasis on their molecular basis, cellular pathways, and cellular targets. This book provides scientific names, botanical classifications, botanical description, medicinal uses, chemical constituents and antiprotozoal activity of more than 100 Asian medicinal plants, with high quality original botanical plates, chemical structures, and pharmacological diagrams and lists hundreds of carefully selected references. It also examines the pharmacological and medicinal applications of Asian medicinal plants especially in drug development for protozoan prevention and treatment. Medicinal Plants in Asia and Pacific for Parasitic Infections is a research tool and resource for the discovery of leads for the treatment of protozoal diseases based on interrelated botanical, biochemical, ethnopharmacological... phylogenetic, pharmacological, and chemical information.

    • Saffron

      • 1st Edition
      • January 23, 2020
      • Maryam Sarwat + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 4 6 2 2
      • eBook
        9 7 8 0 1 2 8 1 8 4 6 3 9
      Saffron: The Age-Old Panacea in a New Light is the first book to detail the functions and effect of saffron in medicinal situations. This book explores the medicinal aspects of saffron and the effect saffron imparts on various diseases of the central nervous system, cardiovascular system, digestive system, locomotor system, urogenital system, eye, skin, and immune system, along with their mechanism of action. This perpetual bulb found mainly in Asia and Europe, Iran, India and Mediterranean countries has been shown to reduce seizures, delay convulsions, and as a neuroprotective agent against cerebral ischemia, brain damage, and Alzheimer's and Parkinson's disease. In addition, it also reduces depression, hypnosis and anxiety and enhances learning and memory skills.

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