Skip to main content
Elsevier
View Cart
My account

Books in Pharmaceutical science general

BooksJournals

    • Inhaled Medicines

      • 1st Edition
      • January 20, 2021
      • Stavros Kassinos + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 9 7 4 4
      • eBook
        9 7 8 0 1 2 8 1 4 9 7 5 1
      Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments.

    • Principles of Translational Science in Medicine

      • 3rd Edition
      • July 15, 2021
      • Martin Wehling
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 4 9 3 1
      • eBook
        9 7 8 0 3 2 3 9 9 9 6 2 5
      • eBook
        9 7 8 0 1 2 8 2 0 4 9 6 2
      Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields.

    • Cancer Immunology and Immunotherapy

      • 1st Edition
      • August 18, 2021
      • Mansoor M. Amiji + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 3 9 7 9
      • eBook
        9 7 8 0 1 2 8 2 3 6 3 7 6
      Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.

    • Practical Aspects of Vaccine Development

      • 1st Edition
      • September 8, 2021
      • Parag Kolhe + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 3 5 7 5
      • eBook
        9 7 8 0 1 2 8 1 4 3 5 8 2
      Practical Aspects of Vaccine Development provides an academic and industry perspective on vaccine development and manufacturing. With the increasing complexity of vaccine products in development, there is a need for a comprehensive review of the current state of the industry and challenges being encountered. While formulation scientists working in biotherapeutic development may be familiar with proteins, vaccines present unique challenges. Vaccines include a wide range of components including proteins, polysaccharides, protein-polysacchari... conjugates, adjuvants, and more. The container closure system may also be unique, and the product may require freezing storage or lyophilization based on the stability of the vaccine components. Based on the route of delivery, novel technologies and devices may be required. Covering formulation development, manufacture, and delivery considerations of vaccine production, this book is essential to formulation scientists, researchers in vaccine development throughout medical and life sciences, and advanced students.

    • Global Perspectives on Astaxanthin

      • 1st Edition
      • April 9, 2021
      • Gokare A. Ravishankar + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 3 0 4 7
      • eBook
        9 7 8 0 1 2 8 2 3 3 0 5 4
      Global Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applications explores the range of practical applications for this molecule, focusing on nutraceutical, pharmaceutical and cosmeceutical products, along with food and feed. This volume brings together the most relevant research, background and future thinking on astaxanthin, focusing on its health benefits. Chapters cover phytopharmaceuticals... industrial production, feeds, downstream processing, regulations, products, color, pigment, cosmetics, bioactive compounds, relationships to other carotenoids, and skin care. The detailed information on its production, processing, utilization and future applications will be of particular use to academic and industry researchers in pharmaceutical sciences, pharmacology and nutrition.

    • Molecular Evolutionary Models in Drug Discovery

      • 1st Edition
      • January 22, 2020
      • Juan Bueno
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 6 1 3 9
      • eBook
        9 7 8 0 1 2 8 1 8 9 2 9 0
      Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings.

    • Preparation of Phytopharmaceuticals for the Management of Disorders

      • 1st Edition
      • November 3, 2020
      • Chukwuebuka Egbuna + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 2 8 4 5
      • eBook
        9 7 8 0 1 2 8 2 0 2 8 5 2
      Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals... nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals... their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery. This book provides key information for everyone interested in drug discovery, including medicinal chemists, nutritionists, biochemists, toxicologists, drug developers and health care professionals. Students, professors and researchers working in the area of pharmaceutical sciences and beyond will also find the book useful.

    • Theory and Applications of Nonparenteral Nanomedicines

      • 1st Edition
      • September 12, 2020
      • Prashant Kesharwani + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 4 6 6 5
      • eBook
        9 7 8 0 1 2 8 2 0 4 6 7 2
      Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

    • Clinical Perspectives and Targeted Therapies in Apoptosis

      • 1st Edition
      • October 15, 2020
      • Rupinder K. Sodhi + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 5 7 6 2 6
      • eBook
        9 7 8 0 1 2 8 1 5 7 6 3 3
      Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research.

    • Quorum Sensing

      • 1st Edition
      • April 6, 2019
      • Giuseppina Tommonaro
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 9 0 5 8
      • eBook
        9 7 8 0 1 2 8 1 4 9 0 6 5
      Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists.

Related subjects

Pharmaceutical science