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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • AI and Data Science in Medical Research

    • 1st Edition
    • Olfa Boubaker
    • English
    AI and Data Science in Medical Research focuses on the integration of AI and data science into medical research, highlighting their impact on drug discovery, medical imaging, diagnostics, and genomic medicine. The book addresses the acceleration of therapeutic compound discovery and optimization of drug development pipelines through AI. The volume also discusses advancements in medical imaging, including early disease detection and neuroimaging. Additionally, it covers the application of AI in genomic medicine, offering insights into personalized treatment strategies.The volume concludes with an examination of AI's role in public health surveillance, particularly in disease detection and epidemiological research.

  • Artificial Intelligence Applications in Emerging Healthcare Technologies

    • 1st Edition
    • Miguel Antonio Wister Ovando + 2 more
    • English
    Artificial Intelligence Applications in Emerging Healthcare Technologies presents the latest advances and state-of-the-art methods and applications of computer science and emerging AI technologies in health and medicine. The book explores the impact of artificial intelligence (AI) in healthcare for medical decision-making and data analysis, tackling topics such as cloud computing, cybersecurity, the internet of things, natural language processing, virtual health, data science applied to healthcare, personalized medicine, imaging, diagnosis, drug discovery, and diseases, among others.Chapters present adaptations or improvements on previous models and algorithms to process data from different sources. Other chapters investigate new formulations for the optimization of known procedures and algorithms. Finally, all chapters use experimental methods to study problems of interest in healthcare. This is a great resource for researchers and students who want to learn how machine learning algorithms and other data science techniques have been implemented to solve healthcare-related problems.

  • Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease

    • 1st Edition
    • Zahra Keshavarz Motamed + 2 more
    • English
    Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease explains how abnormal hemodynamics (blood flow dynamics) greatly alter the cardiovascular system’s ability to transport, control and maintain blood flow throughout the body. These deviations often lead to the initiation and progression of disease. Notably, hemodynamic quantification can be extremely useful for accurate and early diagnosis of cardiovascular disease. Particularly, the ability to monitor and predict hemodynamic effects following specific interventions can significantly broaden lifesaving options. However, image-based computational modelling of predictive hemodynamics analysis methods (and therefore new diagnostic tools) are rare. By extending quantitative methods of analysis, medical professionals can foresee effects of various cardiovascular interventions, allowing for optimized, situation-based care.Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease posits that novel, image-based computational modelling hemodynamic analysis tools will enable the next generation of diagnosis, predictive, and treatment planning resources for cardiovascular disease. Readers will become well-versed in recent advances in hemodynamic approaches, while preparing themselves for the next wave of revolutions in cardiovascular health.

  • Oral Cancer and Artificial Intelligence

    Transforming Diagnosis, Treatment, and Research
    • 1st Edition
    • Sujata Dash + 4 more
    • English
    Oral Cancer and Artificial Intelligence: Transforming Diagnosis, Treatment, and Research explores the intersection of artificial intelligence (AI) and oral cancer care. Sections detail how AI technologies are revolutionizing and evolving diagnosis, treatment, and management, offering new hope and improved outcomes for patients. The book is structured into ten well-defined sections, each addressing a critical aspect of oral cancer care enhanced by AI. It features contributions from leading experts in the fields of AI, oral cancer research, biomedical engineering, and clinical practice from prestigious, worldwide institutions who share valuable insights and their experiences in applying AI to transform oral cancer care. This book is an essential resource for researchers, clinicians, healthcare professionals, and students interested in the transformative potential of AI in oral cancer care. It offers a blend of theoretical knowledge, practical applications, and future directions, making it a comprehensive guide to understanding and leveraging AI to improve outcomes in oral cancer management.

  • Cerebellum Development and Disease

    • 1st Edition
    • Volume 167
    • English
    Cerebellum Development and Disease, Volume 167 offers a comprehensive overview of the intricate processes underlying the formation, maturation, and function of the cerebellum, as well as the wide spectrum of disorders that can affect this essential brain region. Chapters in this new release cover Olivocerebellar circuit development as a substrate for dystonia pathogenesis, Simply complex – that structure of the cerebellar neuronal lineage, Ontogenesis and diversification of cerebellar glia: a developmental perspective, Purkinje cell diversification: a blueprint for cerebellar development, patterning, and evolution, On the Emergence of Folding in the Cerebellum, Scaling and regeneration in the developing cerebellum, ASTN2 in ASD and Neurodevelopmental Disorders, and much more.Additional sections focus on Stem cell-derived in vitro models of human cerebellar development, Development of Spinocerebellar System within the Precerebellar Network, and Cerebellum evo-devo. The book brings together leading experts in neurodevelopment, neurobiology, genetics, and clinical neurosciences to explore the molecular and cellular mechanisms guiding cerebellar development, from embryogenesis to adulthood.

  • Magnetic Resonance Fingerprinting for Quantitative MRI

    • 1st Edition
    • Volume 14
    • Dan Ma + 2 more
    • English
    MR Fingerprinting is emerging as a clinically feasible and versatile tool for quantitative MR imaging. Magnetic Resonance Fingerprinting for Quantitative MRI focuses on all aspects of MR Fingerprinting techniques and applications. Presenting a detailed and clear description of the technology, implementation, clinical translation issues and applications, it emphasizes different perspectives of MR signals and their utilization, with the goal of inspiring readers to explore new MR Fingerprinting designs. The book starts each section with a discussion on rethinking the MR acquisition and the opportunities provided by, for example, different MR contrast mechanisms, signal modeling, post-processing and clinical applications.Magneti... Resonance Fingerprinting for Quantitative MRI is a complete reference for magnetic resonance imaging researchers and radiologists.

  • Equity, Diversity and Inclusion

    Sisyphean Undertaking to an Achievable Reality
    • 1st Edition
    • Faisal Khosa
    • English
    Equity, Diversity and Inclusion: Sisyphean Undertaking to an Achievable Reality explores critical themes across diverse academic disciplines, including business, education, engineering, graduate medical education, health sciences, law, medicine, pharmacy, psychology, public health, and veterinary. Each chapter traces the evolution of its respective discipline, examining how landmark social movements, civil rights milestones, and legislative reforms have shaped the discourse on equity. Alongside these histories, authors introduce key theoretical frameworks that illuminate the concept of intersectionality.Th... book also confronts contemporary challenges head-on. From systemic discrimination and racial profiling to gender inequality and barriers to social and economic mobility, the chapters candidly address the obstacles faced by marginalized groups. More importantly, this volume moves from identifying problems to driving solutions: it offers practical strategies and evidence-based best practices for cultivating equity, diversity, and inclusion (EDI) in workplaces, educational institutions, and communities. Ultimately, it invites readers to embrace the journey toward a more just and inclusive society. It reminds us that while the challenges may be great, the transformation begins with everyone taking that first step.

  • AI-Driven Human-Machine Interaction for Biomedical Engineering

    Concepts, Applications, and Methodologies
    • 1st Edition
    • Kapil Gupta + 4 more
    • English
    AI-Driven Human-Machine Interaction for Biomedical Engineering: Concepts, Applications, and Methodologies offers a comprehensive examination of the intricate relationship between humans and machines, particularly through the transformative lens of artificial intelligence (AI). As AI technologies rapidly evolve, understanding their implications for human-machine interaction (HMI) has become essential across various domains, especially healthcare. Structured into well-defined chapters, the book begins with an introduction to AI-driven HMI, laying the groundwork for understanding its significance in sustainable healthcare and beyond. Subsequent chapters explore critical topics such as machine learning principles, advanced biomedical data classification methods, and the role of AI in telemedicine.Readers will delve into cutting-edge techniques, from deep learning to non-invasive computer vision, while also examining the implications of these technologies across industries. Each chapter equips readers with actionable insights and highlights emerging trends, ethical considerations, and the future of AI in HMI, ensuring a well-rounded perspective on this dynamic field. This is an invaluable resource for researchers, academics, and students in the fields of Biomedical Engineering, Computer Science, Data Science, Artificial Intelligence, and Healthcare Technology.

  • Redefining Global Health in the 21st Century

    • 1st Edition
    • Michael John Alistair Reid + 1 more
    • English
    Redefining Global Health in the 21st Century explores the evolving landscape of global health as the world approaches the conclusion of the Sustainable Development Goals (SDG) era. This comprehensive book examines strides made in global health while emphasizing the urgent need to address emerging and persistent challenges. Topics include shifting patterns of diseases, demographic changes, and the evolving nature of health financing, both internationally and domestically. By providing a thoughtful analysis of these issues, the book equips readers with the insights necessary to navigate the future of global health and contribute to ongoing progress in the field.The book also delves into the importance of decolonization in global health initiatives and the adoption of sustainable, inclusive development models. It serves as a valuable resource for students, policymakers, and stakeholders, guiding future research and policy decisions.

  • Cybersecurity for Healthcare Systems in the Internet of Medical Things Era

    • 1st Edition
    • Janmenjoy Nayak + 2 more
    • English
    Cybersecurity for Healthcare Systems in the Internet of Medical Things Era is driven by the imperative to address the intricate convergence of healthcare, technology, and security. In response to the burgeoning challenges presented by the Internet of Medical Things (IoMT), this book is designed to be an indispensable resource for computer systems experts, healthcare staff, and executives. It goes beyond the surface, offering strategic insights and actionable strategies that encompass not only the IoMT landscape but also the intersection of artificial intelligence, signal processing, and cyber security. Cybersecurity for Healthcare Systems in the IoMT Era serves as a problem-solving compass for a diverse readership in the healthcare landscape. For healthcare professionals and IT leaders, the book untangles the complexities of integrating and securing Internet of Medical Things (IoMT) devices, offering a roadmap for understanding and navigating this rapidly evolving terrain. Biomedical engineers, burdened with strategic and everyday decisions, find in this book strategic insights and actionable strategies, empowering them to make informed choices amidst the ever-changing challenges posed by technology and cybersecurity threats. The authors present a comprehensive guide that not only elucidates the challenges and opportunities presented by IoMT but also explores how the synergy of AI and signal processing can elevate healthcare systems. This integration is crucial in deciphering the intricate nuances of medical data, enhancing diagnostics, and fortifying the security of interconnected healthcare networks.

  • Biophysics of Tissue Self-Organization in Morphogenesis

    The Role of Dynamics Along the Biointerface
    • 1st Edition
    • Ivana Pajic-Lijakovic
    • English
    Biophysics of Tissue Self-Organization in Morphogenesis: The Role of Dynamics Along the Biointerface delves into the interactions between tissue and the extracellular matrix. It explores the fundamentals of cell self-rearrangement and the interrelation between biological mechanisms and physical principles responsible for tissue self-organization. The book examines modeling approaches to tissue self-organization and the application of engineering principles to solve medical problems. It also discusses tools, applications, and medical implications, particularly in embryo development, wound healing, and cancerous diseases, concluding with future developments.Coverin... subcellular to supracellular levels, this book is an interdisciplinary guide for researchers in cell biology, biophysics, developmental biology, and more.

  • Multimodal Data Fusion in Healthcare

    AI Approaches for Precision Diagnosis
    • 1st Edition
    • Akansha Singh + 3 more
    • English
    Multimodal Data Fusion in Healthcare: AI Approaches for Precision Diagnosis explores the transformative potential of AI in modern medicine by integrating diverse data sources such as medical imaging, genomics, EHRs, and wearable sensors. It highlights how AI technologies are revolutionizing healthcare systems through personalized and proactive diagnostics. The book covers cutting-edge methodologies, real-world applications, and the challenges of multimodal data fusion. Topics include AI-driven diagnostics, precision medicine, real-time patient monitoring, and the integration of clinical, genomic, and wearable data, providing both theoretical foundations and practical insights. This book is essential for healthcare professionals, data scientists, and engineers, offering clear frameworks for integrating diverse data types. It addresses crucial issues like data interoperability, privacy, and technical constraints, providing practical solutions. It serves as an invaluable reference for understanding and applying AI advancements in diagnostic precision and personalized medicine.

  • Reverse Aging

    Current Research and Future Directions
    • 1st Edition
    • Sandeep Kumar Singh + 1 more
    • English
    Reverse Aging: Current Research and Future Directions explores the integrated approach of aging and reverse aging to present a comprehensive understanding of the biological, genetic, and molecular mechanisms associated with aging. By targeting fundamental aging mechanisms, strategies are being developed to reverse and repair damage and potentially lead to greater healthspan benefits and optimal longevity. The book opens with the fundamentals of aging and how genetic, environmental, and lifestyle variables affect the biological, psychological, and social processes that lead to aging before delving into a comprehensive review of the hallmarks of aging. Next, an overview of the concept of reverse aging is presented, and subsequent chapters examine specific reverse aging models and approaches. The book explores use of cellular reprogramming techniques, provides an overview of the molecular processes that underlie NANOG-mediated reversal aging, and discusses the possible contribution of IGF-1/PKA signaling reduction to reverse aging via HSC-based therapies. The developing science of rejuvenating stems cells, histone modification, and stimulation of autophagic activity to facilitate the removal of cellular debris and reduce the impact of aging on various organ systems as well as novel concepts of mRNA enhanced cell therapy, immunological-driven signaling, mitochondrial modulations, cell-cycle regulation, and metabolic reprogramming for reserve aging are all examined. The wide range of nutritional therapies, phytochemical, prescription medications, and nutraceuticals impacting the aging process is reviewed, and the book closes with discussion of the revolutionary role AI has on anti-aging research and where the field is headed. In conclusion, the book emphasizes the importance of targeting fundamental aging mechanisms to extend health and achieve optimal longevity and provides insights into the potential implications for healthcare and aging research, highlighting the need for collaborative efforts and interdisciplinary perspectives to address the challenges of population aging and develop effective strategies for healthy aging practices.

  • Artificial Intelligence for Multi-omics Analysis Part A

    • 1st Edition
    • Volume 221
    • English
    Artificial Intelligence for Multi-omics Analysis, Part A, Volume 221 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as an Introduction to Artificial Intelligence in Multi-omics Analysis, Multi‐omics application in health and diseases, Artificial Intelligence in Genomics Analysis, Artificial Intelligence in Single-cell and Spatial Transcriptomics Data, Artificial Intelligence in the prediction of 3D chromatin structure and gene regulation, Artificial intelligence in Mass Spectrometry-based Proteomics, Integrating Artificial Intelligence into Metabolomics for Predicting Diseases, and more.Additional chapters cover Artificial Intelligence in Microbial Metagenomics, Artificial Intelligence in Interactomics, Artificial Intelligence Integration in Medical Imaging Data, AI in biomolecular structural data analysis, Artificial intelligence in Cryo-Electron Microscope data, Explainable artificial intelligence for multi-omics data, and Multi-Omics Cancer Stratification: from Statistical to Deep Learning Perspective.

  • Cell Death Part A

    • 1st Edition
    • Volume 205
    • English
    Cell Death, Part A, Volume 205 explores the diverse mechanisms and methodologies underlying cell death, providing an up-to-date resource for researchers and clinicians in the biomedical sciences. Chapters in this new release include Methodologies for Monitoring Alkaliptosis in Cancer Cells, Protein-complementat... assay and DISC analysis, Detecting phosphorylated MLKL in murine tissues, Establishment of different cell death models (Apoptosis, Necroptosis, Pyroptosis), Implementation of the FENIX assay to determine anti-ferroptotic properties of test compounds, CRISPR-Cas9 knockout screens to identify drug resistance genes in Acute Myeloid Leukemia, and much more.Additional chapters cover Cell death assays for the detection of acute kidney tubular necrosis, Methods of cell death imaging by Incucyte and similar platforms, Super-resolution microscopy-based assessment of organellar redox-active iron distribution and its relevance for ferroptosis, Monitoring inflammasome activation by analyzing ASC specks and oligomerization, LPS-induced sepsis/ and TNF-induced SIRS (In vivo cell death models), Evaluating protease activation and inactivation of gasdermin cell death effectors, and Measurement of plasma membrane rupture via confocal microscopy.

  • Nanotechnology in the Treatment of Infertility

    Practical Applications and Future Insights
    • 1st Edition
    • Pankaj Sharma
    • English
    Nanotechnology in the Treatment of Infertility: Practical Applications and Future Insights delves into the area where nanotechnology meets reproductive health care and reveals how the latest nanoscale developments are changing how infertility is treated. It examines current developments, principles, and possibilities of nanotechnology, with an emphasis on nanoparticle delivery systems, bioengineering, and their relevance in Assisted Reproductive Technologies (ART). This edited volume, written by leading scholars, provides a comprehensive overview of nanotechnology in relation to fertility. It will be of great interest to researchers, healthcare professionals, and anyone who wants to know more about this exciting area of potential solutions for infertility.

  • Direct-Acting Antivirals against Hepatitis C

    Current Issues and Future Perspectives
    • 1st Edition
    • Mohamed Mahmoud Zakaria El-Kassas
    • English
    Direct-Acting Antivirals against Hepatitis C: Current Issues and Future Perspectives is a comprehensive reference that explores Chronic Hepatitis C management. This authoritative reference covers the mechanisms, efficacy, and future potential of Direct-Acting Antivirals (DAAs), offering valuable insights for clinicians, researchers, and students in hepatology and infectious diseases. Structured into three sections, this reference covers a wide range of topics related to DAAs in the management of Hepatitis C. In Section 1, readers will gain a thorough understanding of HCV infection, its clinical significance, and the immune response involved. They will also explore the molecular mechanisms of DAAs and the different classes available. Section 2 focuses on the practical aspects of using DAAs in the treatment of HCV. Readers will discover the clinical efficacy of different DAA regimens, the safety and tolerability considerations, and the additional benefits of DAA treatment beyond virological response. The section also covers current treatment guidelines and individualized approaches for specific patient populations. In Section 3, readers will learn the challenges and future directions in DAA therapy including antiviral resistance in HCV and strategies for managing and overcoming resistance. The book also explores the relationship between DAA therapy and hepatocellular carcinoma, as well as the current limitations and unmet needs in DAA therapy.Direct-Actin... Antivirals against Hepatitis C: Current Issues and Future Perspectives is a comprehensive and indispensable resource for anyone involved in the management of Chronic Hepatitis C. With its in-depth exploration of DAAs, from their molecular mechanisms to their clinical applications and future directions, this book equips clinicians, researchers, and students with the knowledge and insights needed to enhance their practices and contribute to the global fight against HCV infection.

  • Fundamentals of Molecular Structural Biology

    • 2nd Edition
    • Subrata Pal
    • English
    Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.

  • Modern Diabetology

    Basic Science and Clinical Practice
    • 1st Edition
    • R. Paul Robertson
    • English
    Despite extraordinary therapeutic advances since the discovery of insulin 100 years ago, diabetes prevalence continues to rise and significant challenges remain. Modern Diabetology: Basic Science and Clinical Practice provides a concise, one-stop reference that consolidates rapidly evolving research and clinical practice guidelines for today’s endocrinologists, general surgeons, internists, and primary care physicians.

  • Metaverse and AI in Healthcare

    A Federated Learning Approach
    • 1st Edition
    • Jyotir Moy Chatterjee + 1 more
    • English
    Metaverse and AI in Healthcare: A Federated Learning Approach addresses the transformative integration of artificial intelligence and metaverse technologies in healthcare. The book fills a critical gap by exploring how federated learning enables secure, decentralized data sharing and personalized medicine in virtual health platforms, meeting urgent demands for privacy, interoperability, and innovation. The book is structured into four parts covering foundational AI and federated learning concepts, augmented reality and metaverse applications, legal and cybersecurity challenges, and emerging strategic trends.Contributors from academia and industry present chapters on predictive modeling, cybersecurity frameworks, AR fitness, legal perspectives, and AI-driven medical tourism which are supported by case studies and technical explanations. This reference equips graduate students, researchers, and professionals in academia and industry who specialize in computer science, federated learning, biomedical engineering, and digital healthcare with practical knowledge and forward-looking analysis.

  • Deep Learning Assessment of Neurological Imaging

    • 1st Edition
    • Tripti Goel + 3 more
    • English
    Deep Learning Assessment of Neurological Imaging provides an introduction to deep learning structures and pre-processing methods for detecting MRI anomalies. The book also provides a comprehensive accounting of deep learning research on MRI images for Alzheimer's disease, Parkinson's disease, and schizophrenia, and includes a discussion on current research issues and future objectives. This book is a valuable resource to guide new entrants in the field, helping them make a meaningful impact in their development efforts. The book concludes with a brief overview of problems and potential future advancements in the field.

  • Biostatistical Methods and Applications

    Experiment Design, Analysis, and Presenting Findings
    • 1st Edition
    • Jitendra Kumar Chaudhary
    • English
    Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings provides students and researchers with the skills needed to apply biostatistical concepts and implement a wide range of analytical tools. The text is an accessible and intentionally curated resource that instructs readers in designing experiments, considering the results, and presenting statistical findings and views. In twenty-four chapters and additional appendices, the book starts with an introduction to the field of statistics and from there covers experiment design, data coding, and data collection methods. The book also delves into descriptive statistics, probability, statistical distributions, correlations, and regression. Common research techniques such as normality tests, sample size determination, missing data analysis, statistical inference, test of significance, and ANOVA are explained in a clear manner so that readers can successfully understand and apply these methods. Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings thoroughly explores fundamental topics in biostatistics to guide readers in conducting statistical analysis and interpretation by using the step-by-step procedures and diagrams in the book. This book covers current topics which are being used frequently in teaching and research areas, as well as specific statistical techniques including multivariate analysis, binary logistic regression, and non-parametric methods. This valuable first edition provides the necessary tools and conceptual foundations in quantitative reasoning to efficiently extract information from a vast sea of data, and to communicate research findings in order to support hypotheses and give credibility to research methodology and conclusions. With detailed explanations, illustrative examples and diagrams, and beneficial in-text exercises and solutions to support the study of biostatistics, this textbook will prove useful to students, researchers, and scientists who aim to increase their precision around methods and techniques in this field.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 132
    • English
    Advances in Clinical Chemistry, Volume 132 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including MicroRNAs in Cardiovascular Disease, Salivary Biomarkers in Oral Diseases: From Caries to Cancer – Advances, Challenges, and Future Directions, Exercise Biomarkers, Glycoproteomics of Body Fluids and Derived Exosomes in Hepatocellular Carcinoma, Vitamin D in Health and Disease and Potential Shield Against COVID-19, and RNA Biomarkers in Hemorrhagic Stroke.

  • Public and Environmental Health

    Shaping Tomorrow for a Sustainable Future
    • 1st Edition
    • Ranbir Chander Sobti + 1 more
    • English
    Public and Environmental Health: Shaping Tomorrow for a Sustainable Future offers an in-depth exploration of the latest developments, strategies, and research in these intertwined fields, providing readers with a comprehensive understanding of how to improve health outcomes through innovative approaches and informed public policy. Sections address how individuals and communities can make informed health decisions for better health outcomes, present the myriad of challenges the environment poses, including climate change, and how global cooperation, policy interventions, and sustainable practices can help improve outcomes for communities across the world. Additional content details how surveillance and epidemiological research are foundational to public health at both a national and international level, allowing authorities to respond promptly to threats, allocate resources effectively, and implement targeted interventions. Written by experts from across the globe, this book is ideal for public health administrators, researchers, students, and NGOs involved in public health programs and the environment.

  • Wearable Sensing and Assistive Devices for Robotic Rehabilitation

    • 1st Edition
    • Wei Meng + 4 more
    • English
    Wearable Sensing and Assistive Devices for Robotic Rehabilitation provides an overview of current research and developments in the field of innovative technologies for advanced wearable sensing and assistive devices in medical rehabilitation. The book presents a systematic investigation into the wearable acquisition and deep learning-based processing of biological signals and applications with wearable robotic devices. It provides fundamental bio-mechatronics engineering knowledge to analyze and design new wearable sensing and assistive devices.In addition, the book includes human wearable sensors design and development, biological signals acquisition and processing, brain-computer interface and neuromuscular interfaces, wearable exoskeleton and soft robotic devices, and human-centered interactive robot control.

  • Immunomodulators - Part A

    • 1st Edition
    • Volume 151
    • English
    Immodulators, Volume 151 explores the pivotal role immodulators play in regulating immune responses for health and disease management. The book provides an in-depth overview of various classes of immunomodulatory agents, including biologics, small molecules, natural compounds, and synthetic drugs, examining their mechanisms of action and therapeutic applications. Chapters in this new release include Marine-Derived Polysaccharides and Peptides as Next-Generation Immunomodulators: Molecular Mechanisms, Therapeutic Potential, and Translational Challenges, Advances in Immunomodulation: From Dietary Influence to Computational Precision, iPSC-derived immunotherapy for Tau and Alzheimer's disease, and much more.Additional sections cover Antibodies targeting amyloid-β and Tau oligomers in Alzheimer's Disease, Biosimilars: Antibody and Nanobody Based Therapeutic Approaches Towards Protein Misfolding Diseases, Immunomodulator drugs: mechanisms of action and systemic effects, Microbiome and microbial products as immunomodulators: implication for gastrointestinal cancers, Integration of Network pharmacology, docking, and dynamics analysis to investigate the immunomodulatory activity of Pongamia pinnata, Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A bioinformatics Approach, Utilizing DREIMT Database for Drug Prioritization in Immunomodulatory Therapy for Psoriasis and Psoriatic Arthritis, and many additional topics.

  • Comparative Fish Immunology

    • 1st Edition
    • Volume 42
    • English
    Comparative Fish Immunology, Volume 42 in the Fish Physiology series, presents chapters written by leading experts. Covering a broad range of topics, this edition explores the evolution and function of immune systems in fish, with particular attention to both innate and adaptive immune mechanisms across diverse aquatic species. Chapters examine adaptive immunity in jawless vertebrates and the unique VLR system, the role of antimicrobial peptides in teleost infections, and the use of zebrafish as a model for studying innate immune responses. Additional contributions explore pharyngeal mucosal lymphoid structures, the evolutionary origins of germinal centers in fish, and mechanisms of antigen presentation in teleosts.Other chapters address microbiota–host immune interactions, emerging insights into teleost neuroimmunology, and the modulation of immune function through behavioral fever. Together, these contributions provide a comprehensive overview of current discoveries and evolving perspectives in fish immunology, offering valuable insights for researchers, immunologists, and aquatic biologists interested in the physiology and immune biology of fishes.

  • Autophagy – Part A

    • 1st Edition
    • Volume 403
    • English
    Autophagy – Part A, Volume 403 explores the fundamental biological process of autophagy. Beginning with the historical discovery and molecular mechanisms of autophagy, the book delves into its regulation, physiological roles, and significance in maintaining cellular homeostasis. Chapters in this new release include Ciliophagy: Maintaining Primary Cilium Homeostasis to Prevent Cilium-Related Diseases, Unraveling the interplay of glycolysis, lactylation, and autophagy, Autophagy and Type 2 Diabetes: Bridging the Gap in Metabolic Health, Autophagy in Cancer Cachexia: From Mechanisms to Therapeutic Opportunities, Glycophagy: A Selective Autophagy Pathway for Glycogen Degradation, Role of Autophagy in Adipose Tissue: Implications for Metabolic Health, and more.

  • 2D and 3D Cellular Screening Models and AI Guided Analysis

    • 1st Edition
    • Volume 204
    • English
    2D and 3D Cellular Screening Models and AI Guided Analysis, Volume 204 explores the development, application, and comparative benefits of 2D monolayer cultures and 3D organoids, spheroids, and tissue-engineered constructs for biomedical research and drug discovery. Chapters in this new release include High throughput CellTiter-glo viability assessment, Assessing viability of cancer cell spheroids in 3D drug screening, 3D killing assay of cancer spheroids by cytotoxic T lymphocytes in anchored microfluidic droplets, Use of micropatterning for 3D cell culture, Use of microfluidic chip devices for assessing the effect of radiation on 3D cell culture models, and much more.Additional chapters cover A 3D model for assessing regulated cell death modalities, YOLO detection model for Cell Viability assessment, Bioinformatics and AI/ML approaches using multi-omics data to accelerate diagnosis and delivery of precision care, Automated image analysis and machine learning for the assessment of mitochondrial membrane potential, Assessing cancer cell heterogeneity in patient-derived tumoroids, Assessment of lysosomal drug sequestration and release using fluorescence microscopy, Assessment of T cell toxicity in ex-vivo models of cancer, Three-dimensional Organoid Screening using Leica Thunder Microscope, Using vascularized organoids-on-chip for assessing systemic drug delivery, and many more interesting and timely topics.

  • Epigenetic Regulation of Cancer - Part E

    • 1st Edition
    • Volume 400
    • English
    Epigenetic Regulation of Cancer, Part E, Volume 400 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic regulation of cancer, Phytochemicals with epigenetic properties and their role in melanoma therapy, Epigenetic Insights of MicroRNAs: Pioneering Cancer Detection via Advanced Biosensors, Epigenetic Regulation of Autophagy in Cancer: A Double-Edged Sword in Tumor Progression and Therapy Resistance, Epigenetic Regulation via Histone Modifications in Ovarian Cancer, The current findings and potential applications of breast cancer epigenetics, and much more.Other chapters cover the Application of bioinformatics and data science in studies of cancer epigenetics, and much more.

  • Cytoskeletal Proteins in Neurodegenerative Diseases

    • 1st Edition
    • Volume 150
    • English
    Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS). Chapters in this new release include Cytoskeletal proteins regulates Tau in Alzheimer's Disease, "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins", Glial Fibrillary Protein is potential biomarker For AD, and much more. Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.

  • Growth Hormone and Related Disorders: From Clinics to Diagnosis

    • 1st Edition
    • Volume 131
    • English
    Growth Hormone and Related Disorders: From Clinics to Diagnosis, Volume 131 covers various topics related to growth hormone and its associated disorders when there is a GH excess, including their pathophysiology, clinical presentation and diagnosis. Chapters in this new release include Growth hormone: synthesis and regulation, GH and GnRH-gonadotropin secretion, Co-Secreting Pituitary Adenomas in Acromegaly: Classification, Diagnosis, and Treatment Strategies, Growth hormone and glycemic metabolism, Acromegaly: pathophysiology and etiology, Acromegaly: biochemical diagnosis, Acromegaly and clinical manifestations, and more.Additional sections discuss Gigantism, Acromegaly and genetics, Molecular markers of response to medical therapy in acromegaly, and Acromegaly and histopathology.

  • Host-Microbe Co-metabolism System in Health and Disease

    • 1st Edition
    • Xiao Zheng + 1 more
    • English
    Host-Microbe Co-metabolism System in Health and Disease is an easy-to-follow reference of research progress in host-microbiome co-metabolism system (HMMS) and how this frontier could imply a better understanding of health, disease, and the discovery of novel drugs. The book summarizes recent studies that are progressing to complete a panorama of the host-microbiome co-metabolism system (HMMS) in health and disease. It discusses how sophisticated bioanalytical tools, tractable model organisms, and artificial intelligence could be integrated to answer key biological questions related to HMMS in the broader context of human health and drug discovery.

  • Role of Nanocarriers in Management of Non-Hodgkin Lymphoma

    • 1st Edition
    • Bhupendra G. Prajapati + 1 more
    • English
    Role of Nanocarriers in Management of Non-Hodgkin Lymphoma is a pivotal resource that explores the transformative impact of nanotechnology on the diagnosis, treatment, and management of non-Hodgkin’s lymphoma (NHL). This comprehensive guide bridges the gap between innovative research and clinical application, focusing on advancements in polymeric nanoparticles, lipid carriers, carbon nanotubes, and immunotherapy approaches. The book provides an in-depth analysis of current technologies and future directions in integrating nanocarriers into NHL management. Each chapter offers evidence-based insights and mechanisms of action, emphasizing the synergy between immunotherapy, precision medicine, and nanotechnology. This resource benefits its academic audience by equipping healthcare professionals with innovative strategies to improve treatment outcomes and inspiring researchers to explore novel therapeutic pathways. By fostering interdisciplinary collaboration among oncologists, pharmaceutical developers, and nanotechnology experts, the book ultimately guides future research to enhance patient care in the rapidly evolving field of non-Hodgkin’s lymphoma management.

  • Role of Biomarkers in Cancer Diagnosis and Therapeutics

    • 1st Edition
    • Sushama Talegaonkar + 2 more
    • English
    Role of Biomarkers in Cancer Diagnosis and Therapeutics offers a thorough exploration of the critical roles biomarkers play in cancer detection, diagnosis, monitoring, and therapy. Sections focus on established and emerging biomarkers like PSA and CEA, detailing their biochemical characteristics and clinical relevance, and examining metabolic pathways utilized by cancer cells, highlighting key enzymes and their therapeutic potential. The final part pf the book discusses innovative strategies targeting cell cycle checkpoints and DNA repair mechanisms, including synthetic lethality through PARP inhibitors. This essential resource provides researchers and clinicians with insights into novel metabolic targets and cutting-edge treatment strategies.By addressing current applications and future challenges, including the integration of AI and multi-omics approaches, the book equips readers with actionable knowledge to advance personalized cancer care and navigate the dynamic landscape of oncology.

  • Roadmap to Successful Digital Health Ecosystems

    A Global Perspective
    • 2nd Edition
    • Evelyn J.S. Hovenga AM + 1 more
    • English
    Roadmap to Successful Digital Health Ecosystems: A Global Perspective, Second Edition, explores the transformative integration of digital health technologies to enhance healthcare delivery and patient outcomes. This book provides a comprehensive overview of the evolving landscape of digital health, focusing on next-generation systems and the role of artificial intelligence in creating efficient healthcare ecosystems. The revised content covers topics such as regional implementation experiences, workforce management, and precision healthcare. New chapters highlight advancements in digital health technologies, case studies from Jamaica and Africa, and strategies for addressing fragmentation in healthcare systems. The book emphasizes ethical AI use and proactive, integrated healthcare approaches. For the academic audience, this revision serves as an essential resource, compiling cutting-edge research and practical applications that inform best practices in digital health. It equips researchers, educators, and practitioners with the knowledge needed to navigate the complexities of digital health ecosystems and drive innovation in their fields.

  • Unlocking the Secrets of Extracellular Vesicles and Exosomes

    A Journey into the Cutting-Edge Frontier of Cellular Communication
    • 1st Edition
    • Chandrashekhar Singh + 4 more
    • English
    Unlocking the secrets of extracellular vesicles and exosomes: A journey into the cutting-edge frontier of cellular communication provides a comprehensive overview of the latest advances and research on extracellular vesicles (EVs) and exosomes. The book begins with a historical introduction to the field and how this has evolved since EVs were first observed, before exploring their cellular mechanisms and approaches to study their isolation, characterization, and function. It then delves into exosomes in health and disease, considering their role across cancer, regenerative medicine, neurological disorders, and metabolic disorders, highlighting their potential as biomarkers for disease diagnosis. The book moves on to discuss cutting-edge technology for the engineering of EVs and exosomes, considering how the integration of AI, machine learning, and nanotechnology can be utilized to expand the therapeutic capabilities of EV and exosome-based applications. It then closes with chapters covering novel applications in nutraceutical and cosmetic production, and a look towards the future potential of EVs and exosomes. Unlocking the secrets of extracellular vesicles and exosomes offer a thorough exploration of EV and exosome research, covering various dimensions from basic science to clinical applications and future perspectives. It is an ideal guide for researchers working across a diverse range of disciplines, including cell biology, molecular biology, biotechnology, therapeutics, and biomedicine.

  • Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions

    • 1st Edition
    • Volume 728
    • English
    Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions, Volume 729 provides a broad snapshot of state-of-the-art methods for studying biological lipids and biomembranes. Sections in this new release cover De novo chemoenzymatic construction of lipid membranes, Photoaffinity labeling for cholesterol metabolism, Expression and Characterization of Phospholipase Cb and Ce enzymes, Assembling Retromer-coated membrane tubules for in vitro structure-function studies, Quantitative analysis of S-acylation, Inhibition of palmitoyltransferase... Exploiting protein lipidation to create peptide-based biomaterials, and much more.Additional sections discuss Optogenetic control of lipid-modifying enzyme activity using LOV domain insertions, Chemoproteomics approaches for inhibition of diacylglycerol kinases, Inhibition of sterol transfer protein function, Preparation of K-Ras4B containing synthetic modifications via expressed protein ligation, Regulation of lipin enzymes on membranes, Use of novel synthetic analogues to decipher the interactions of phosphatidic acids species, Analyzing lipid-nuclear receptor interactions, and much more.

  • Explainable AI in Clinical Practice

    Methods, Applications, and Implementation
    • 1st Edition
    • Arvind Panwar + 4 more
    • English
    Explainable AI in Clinical Practice: Methods, Applications, and Implementation bridges the gap between artificial intelligence capabilities and their practical implementation in healthcare. The book explores applications of explainable AI in diagnostic support and treatment planning, offering insights into making AI systems interpretable and accountable. Through real-world case studies and ethical frameworks, readers learn to transform opaque AI systems into tools that enhance clinical practice while maintaining high patient care standards. This volume unites leading experts to provide a comprehensive framework for implementing explainable AI, ensuring that AI-driven decisions are transparent, trustworthy, and clinically sound. Targeted solutions in the book cater to diverse stakeholders in the healthcare AI ecosystem. Healthcare professionals will gain confidence in integrating AI tools, while technical teams will receive implementation guidelines. This book is essential for anyone seeking to responsibly and effectively navigate the complexities of AI in healthcare.

  • A Complete Guide to Hysteroscopic Myomectomy

    • 1st Edition
    • Rahul Manchanda + 2 more
    • English
    A Complete Guide to Hysteroscopy Myomectomy provides an evidence-based, comprehensive treatise on hysteroscopic myomectomy, a valuable option for treating uterine fibroids that offers a less invasive alternative to traditional surgeries like hysterectomies and laparotomies. This complete guide helps readers master how to diagnose and select the most appropriate strategy of treatment, describing all aspects of each strategy and applying the knowledge in different clinical settings. This is an essential reference for anyone in the research and medical field. It's also ideal for patients who want to understand the procedure's benefits, indications, and recovery process to make informed decisions about their treatment options.

  • Artificial Intelligence in Gastrointestinal Cancers

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 2 more
    • English
    Artificial Intelligence in Gastrointestinal Cancers examines the transformative impact of AI technologies on diagnosing and treating gastrointestinal malignancies. This book explores how advanced algorithms, particularly deep learning models, enhance the analysis of medical imaging, including endoscopic, MRI, and CT scans, facilitating earlier and more accurate identification of cancers such as esophageal, stomach, colorectal, and pancreatic cancers. The content covers AI's multifaceted applications, from improving diagnostic accuracy to personalizing treatment strategies based on genomic and clinical data. It discusses how machine learning predicts patient outcomes and optimizes treatment plans while also addressing AI's role in accelerating drug discovery and clinical trials. For an academic audience, this book provides crucial insights into AI's current and future applications in GI oncology. Readers gain a comprehensive understanding of AI diagnostic tools and personalized treatment strategies, equipping researchers and clinicians with the knowledge to leverage these advancements for improved patient care and outcomes in gastrointestinal cancers.

  • Gross Pathology Atlas

    A Guide to Gross Specimens Evaluation
    • 1st Edition
    • Neda Zarrin-Khameh + 2 more
    • English
    Gross Pathology Atlas: A Guide to Gross Specimen Evaluation is a novel reference dedicated to 'gross' images. Gross pathology is the branch of pathology that deals with the examination and diagnosis of diseases through the observation of organs, tissues, and bodily fluids with the naked eye, without the aid of a microscope. It involves the examination of specimens obtained during surgery, autopsy, or biopsy. This book serves as an essential tool for diagnosing diseases. By observing macroscopic features, pathologists can identify diseases or conditions affecting various organs and tissues for example, to detect tumors, inflammation, infections, and degenerative changes. Gross pathology specimens serve as invaluable teaching aids for medical students, residents, and healthcare professionals. They provide tangible examples of disease manifestations, facilitating the understanding of pathological processes. Moreover, gross pathology specimens are essential for research purposes, allowing scientists to study disease mechanisms, develop new treatments, and advance medical knowledge.

  • Revolutionizing Cancer Treatment

    The Power of Molecularly Imprinted Polymers for Precision Therapy
    • 1st Edition
    • Bhupendra G. Prajapati + 3 more
    • English
    Revolutionizing Cancer Treatment: The Power of Molecularly Imprinted Polymers for Precision Therapy examines the transformative role of molecularly imprinted polymers (MIPs) in cancer management and treatment. This comprehensive book explores how MIPs can be utilized to create advanced drug delivery systems specifically targeting various cancer types, including breast, prostate, and lung cancers, among others. By integrating molecular imprinting techniques with precision oncology, this resource provides valuable insights for researchers, clinicians, and pharmaceutical developers aiming to enhance cancer therapies. Structured in a user-friendly format, the book includes detailed chapters dedicated to specific cancer types, highlighting the design and application of MIPs in targeted therapies. Users will find flow charts, process diagrams, and case studies to facilitate understanding of complex concepts. The necessity for this book arises from the pressing demand for precision medicine in oncology, as conventional treatments often suffer from issues of specificity and efficacy. Ultimately, this work serves as a vital reference for students, researchers, and healthcare professionals dedicated to advancing cancer treatment through innovative drug delivery systems.

  • Natural Language Processing for Healthcare

    The Rise of Intelligent Assistants
    • 1st Edition
    • Laxmi Shaw + 2 more
    • English
    Natural Language Processing for Healthcare: The Rise of Intelligent Assistants addresses the critical gap between cutting-edge AI research and its practical applications in healthcare, offering an accessible guide tailored to the unique challenges of medical environments. It highlights how NLP technologies are revolutionizing patient care, medical documentation, and clinical decision-making while emphasizing ethical, legal, and interoperability considerations. Structured into four sections, the book begins by laying foundational knowledge in NLP and healthcare data, covering concepts such as tokenization, medical ontologies like UMLS and SNOMED CT, machine learning models, including BioBERT and ClinicalBERT, and emerging impacts of large language models like GPT.The applications section explores real-world implementations of intelligent assistants, such as virtual health chatbots, clinical documentation tools, conversational AI for patient engagement, and voice recognition integrated into electronic health records. Technical chapters provide insights into system architectures, evaluation metrics, data privacy, security, and interoperability standards like FHIR. The final section looks ahead to future directions including multilingual NLP, federated learning for privacy preservation, and the evolving landscape of AI-driven healthcare assistants. This book is an indispensable resource for a broad audience.

  • The Cardiac Conduction System

    Evolution, Development, and Therapeutic Potential
    • 1st Edition
    • Bjarke Jensen + 1 more
    • English
    The Cardiac Conduction System: Evolution, Development, and Therapeutic Potential, the latest release in the Hot Topics in Physiology series, provides the reader a thorough and comprehensive review of this intricate system. The book covers conventional topics: anatomy, electrophysiology, and key cellular characteristics, as well as emerging topics: patient specific computer modelling, induced pluripotent stem cells, and in vivo editing as state-of-the-art treatment strategy. Given the exhaustive coverage of topics, this book is "go-to reference" for the cardiac conduction system for years to come.This volume was published in association with the International Union of Physiological Sciences (IUPS). It is an ideal reference for academics and researchers in anatomy, physiology, cardiology, electrophysiology, biomedical engineering and medical education at Undergrad, Masters, PhD, and Post-Doc levels.

  • Handbook of Material Biodegradation, Biodeterioration, and Biostablization

    • 3rd Edition
    • George Wypych + 2 more
    • English
    Handbook of Material Biodegradation, Biodeterioration, and Biostabilization, Third Edition provides extensive information on the microorganisms involved in the biodegradation of materials, along with the biocides which are permitted for use according to the most up-to-date worldwide legislation. The book focuses on protecting materials and products against colonization and subsequent degradation of their properties. Mechanisms of biodegradation and biodeterioration, results of biodeterioration, and methods of biostabilization are covered for a large number of products, making the title relevant for a range of industries and applications, including construction, coatings/paints, medical and pharmaceutical applications, and electronics. It also covers 13 groups of bacteria, 7 groups of fungi, and 4 groups of protozoa involved in biodegradative processes. In addition, the health and safety aspects of biocide application are covered in detail, as well as the personal protection of practitioners who are required to use them. The contents and the most-up-to-date information make this book essential for almost all the fields of applied chemistry.

  • Mathematical Concepts and Methods in Modern Biology

    Using Modern Discrete Models
    • 2nd Edition
    • Raina Robeva
    • English
    Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models, Second Edition presents an updated, quantitative framework for analyzing, predicting, and modulating complex biological systems. Structured around project-based learning and problem-solving, it integrates essential mathematical concepts and methods in the context of key biological questions. Topics include gene regulatory and neuronal networks, CpG islands, plant population growth, interacting populations, phylogenetics, and phylogenomics. Modeling tools span discrete dynamical systems (including deterministic and stochastic Boolean networks), ordinary differential equations, projection matrices, agent-based modeling, polynomial ideals, Gröbner bases, tropical algebra, and other algebraic approaches. Computation is supported by a range of software tools, including some developed for this book, as well as open source, freely available, and proprietary platforms. Updated code examples and step-by-step instructions illustrate software use, making this a valuable resource for health professionals, scientists, researchers, and students in related fields.

  • The Resistance of Cervical Cancer to Chemotherapy and its Reversal

    • 1st Edition
    • Volume 9
    • S. Muthusami
    • English
    The Resistance of Cervical Cancer to Chemotherapy and its Reversal provides a holistic understanding of cervical cancer development, immune-evading mechanisms of HPV, immunotherapies available, methods to study cervical cancer and the development of newer drugs. Content shows the involvement of signaling pathways during chemoresistance in cervical cancer, the involvement of genes in drug resistance, and introduces long noncoding RNAs as novel biomarkers.In 10 chapters, this book first provides an introduction and history of cervical cancer; next, it discusses the influence of viruses on cervical cancer and finally, it describes therapies to overcome chemotherapy resistance in cervical cancer. This is the perfect reference to provide the fundamental base of knowledge needed for oncologists, pharmacologists, translational investigators, immunotherapists, scientists, and clinicians interested in building a comprehensive understanding of the field.

  • Epigenetic Regulations in Gastrointestinal Cancers

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 1 more
    • English
    Epigenetic Regulations in Gastrointestinal Cancers offers a comprehensive exploration of the genomic and epigenomic alterations that underpin the aggressive nature of gastrointestinal (GI) cancers. . By synthesizing the latest research and insights into the role of the tumor microenvironment and cellular signaling pathways, this book aims to elucidate the multifaceted nature of GI cancer neoplasia and propose innovative therapeutic strategies. Addressing critical challenges in GI cancer research and treatment, this book serves as a vital resource for researchers and clinicians striving to bridge the gap between basic research and clinical application. It tackles the complexities of GI cancer mechanisms by integrating knowledge from diverse fields, thereby providing a holistic understanding essential for effective therapeutic development. Through real-world case studies and expert contributions, the book highlights successful treatment regimens that leverage epigenetic insights, thereby fostering dialogue among multidisciplinary teams and promoting collaborative approaches to cancer care. Moreover, the book emphasizes the importance of staying abreast of rapid advancements in the field of cancer research. With contributions from leading experts and an accompanying online platform featuring interactive resources, readers will have access to the latest insights and developments in GI cancer research. By identifying specific epigenetic targets and innovative strategies for overcoming treatment resistance, this book aspires to enhance patient outcomes in GI cancers and contribute to the ongoing evolution of personalized medicine in oncology.

  • Genetics of Bone Biology and Skeletal Disease

    • 3rd Edition
    • Rajesh V. Thakker + 3 more
    • English
    Genetics of Bone Biology and Skeletal Disease, Third Edition is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid, and related disorders, and vitamin D and renal disorders.Sections cover bone biology and structure, joint and cartilage biology, principles of endocrine regulation, the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasia, rarer bone disorders, and much more.

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