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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Peptide Catalysts, including Catalytic Amyloids

    • 1st Edition
    • Volume 697
    • English
    Peptide Catalysts, including Catalytic Amyloids, Volume 697 in this esteemed series, highlights new advances in the field, with this new volume presenting interesting topics on Screening of oxidative behaviors in catalytic amyloid assemblies, Catalytic amyloids derived for natural proteins, AFM-IR studies of catalytic amyloids, MD structural studies of catalytic amyloids, Characterization of crystalline, amyloid-like amino acid assemblies, Computational modeling of supramolecular peptide assemblies, and Assembly and activity of short prion-inspired peptides.

  • Nano-Enzyme Incorporated Particles

    Fundamental Concepts, Synthesis and Applications
    • 1st Edition
    • Veleeswaran Ananthi + 2 more
    • English
    Nano-Enzyme Incorporated Particles: Fundamental Concepts, Synthesis and Applications focuses on integrative approaches of the enzyme nanoparticle synthesis and its applications on biomedicine, biosensors and biocatalysis. The book discusses the vital activities of nanozymes in enzyme mimicking processes and covers the latest methods and procedures involved. Divided into five sections, this book covers the production and characterization of enzyme nanoparticles, the activities, properties, and applications of enzyme nanoparticles, the development of nanocatalysts as analytical tools, and the degradation of nanoparticles. It covers potential investigations regarding aspects of production, characterization, and applications of enzyme incorporated nanoparticles.

  • Allergic Asthma Immunopathogenesis

    Immunopathology of the Allergic Asthma
    • 1st Edition
    • Seyyed Shamsadin Athari + 1 more
    • English
    Allergic Asthma Immunopathogenesis: Immunopathology of the Allergic Asthma presents a new glance to the allergic asthma pathophysiology by focusing on the immunopathogenesis and allergo-inflammation mechanisms of asthma and cell signaling pathways that can be used for various research purposes, including the design of anti-asthma treatment and target therapy for scientists and researchers. As asthma is a chronic, complicated airway disease whose mortality and morbidity rates have increased worldwide, some common treatments for asthma cannot control it nor even prevent simple inflammation and relieve shortness of breath. Thus, understanding its molecular pathways and pathophysiology is required in order to better understand the disease.

  • Cannabis and its Derivatives

    Guide to Medical Application and Regulatory Challenges
    • 1st Edition
    • Rahul Shukla + 3 more
    • English
    Cannabis and its Derivatives: Guide to Medical Application and Regulatory Challenges summarizes the current state of research and clinical pharmacology of cannabis-based therapeutics, along with associated regulatory frameworks. Sections cover historical, botanical, and taxonomical platforms of cannabis, chemical derivatives of the cannabis plant, a literature review of therapeutic applications, the biological fate of cannabis and its metabolic products, pain management, neurological disorders, cancer management, interactions with other drugs, veterinary applications, and the adverse effects of Cannabis overuse in humans.The book's final section is devoted to discussions around regulatory challenges and future considerations. This is the ideal reference pharmaceutical scientists, clinicians, and academic researchers who want access to updated information on the therapeutic applications of cannabis and its derivates. Corporate researchers will also benefit from this book’s presentation of the associated regulatory environment.

  • Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies

    Shaping Digital Future
    • 1st Edition
    • Patricia Ordonez de Pablos
    • English
    Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies: Shaping Digital Future provides insight to the potential of advanced information technologies to build stronger healthcare systems, better quality healthcare services, and more resilient societies. The book covers two important regions: Gulf Region (Bahrein, Kuwait, Oman, Qatar, and UAE) and Asia, and explores how these countries develop policies for healthy aging and how digital tools can serve these goals. This book delivers a collection of relevant, innovative research works on digital healthcare, with four main goals: (1) to cover two geographical regions (Asia and Gulf Region) with important advances in digital healthcare; (2) to present case studies in the field of IT and digital health during the pandemic and analyze the lessons from these studies; (3) to evaluate the latest advances in the field of digital healthcare (especially Artificial Intelligence [AI], Big Data, Blockchain, and 5G); and (4) to discuss implications for main stakeholders (patients, doctors, IT experts, directors, and policy managers) and recommendations for policy makers in these two regions and elsewhere.

  • Targeting Signaling Pathways in Solid Tumors Part B

    • 1st Edition
    • Volume 386
    • English
    Targetting Signaling Pathways in Solid tumour Part B, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Biological Insights of Multi-Omics Technologies in Human Diseases

    • 1st Edition
    • Aarif Ali + 3 more
    • English
    Biological Insights of Multi-Omics Technologies in Human Diseases provides detailed information about the basics of multi-omic technologies, including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters, this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives.The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Mechanoluminescence in Organic and Inorganic Compounds

    Basic Concepts, Instrumentation, and Applications
    • 1st Edition
    • Vikas Dubey + 3 more
    • English
    Mechanoluminescence in Organic and Inorganic Compounds: Basic Concepts, Instrumentation, and Applications provides a comprehensive overview of mechanoluminescence for newly qualified researchers and scientists across multiple related fields. It serves as a guide for budding scientists to advance in the field through various applications covered in this book, such as energy, mechanics, medicine, and optics. This reference shines light on the pros and cons of utilizing organic or inorganic mechanoluminescent materials, making it a handy tool for researchers worldwide involved in luminescence and applications such as optoelectronics, sensors, forensics, displays, energy harvesting, and smart robotics. The editors and their expert contributors summarize these applications, making it a valuable resource for academics, researchers, and those working in industry.Mechanolumi... in Organic and Inorganic Compounds contains broad coverage, which progresses from theory to applications, serves as a complete reference of global research and experience, which will work to inform and guide the development of more efficient devices for the future.

  • New Approach for Drug Repurposing Part A

    • 1st Edition
    • Volume 205
    • English
    New approach for drug repurposing represents drug discovery and development which is a tedious process that requires 10-15 years of time, investments up to $1-2 billion, and have high risk of failure to enter into market for clinical applications. As the drugs has to pass through number of developmental phase, the likelihood for a drug to be approved from phase I clinical trial to United States of Food and Drug Administration (USFDA) approval is less than 10%. More than 90% of drugs failed in due to toxicity, efficacy and clinical trials. Drug repurposing is one of the roadway to accelerating drug discovery and development for treating disease and thus to providing better quality of life. This volume covers an overview of drug repurposing, novel methods, mechanism of action, lab on chip for drug repurposing, computational biology, system biology, artificial intelligence and machine learning for drug repurposing, target identification, target mining, high throughput drug screening, clinical trial of repurposed drug, repurposed biologics, and regulatory consideration and intellectual property right of repurposed drug. This volume highlights a number of aspects of the drug repurposing that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 127
    • English
    Advances in Applied Microbiology, Volume 127 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Advances in Artificial Intelligence

    Biomedical Engineering Applications in Signals and Imaging
    • 1st Edition
    • Kunal Pal + 2 more
    • English
    Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of arti­ficial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical ­ eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.

  • Phylogenomics

    Foundations, Methods, and Pathogen Analysis
    • 1st Edition
    • Igor Mokrousov + 1 more
    • English
    Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 120
    • English
    Advances in Clinical Chemistry, Volume 120, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.

  • Immunology for Engineers

    • 1st Edition
    • Volume 140
    • English
    Immunology for Engineers, Volume 140 consists of chapters from stalwarts of the field, covering topics such as antibody engineering, adjuvant requirement and its methodology for assessment, and the need to develop immunotherapy, etc. Chapters covered in this volume discuss Current Status and Future Prospective of Breast Cancer Immunotherapy, Engineering high affinity antigen binders- beyond antibodies, Platelets and Inter-Cellular Communication in Immune Responses: Dialogue with both Professional and Non-Professional Immune Cells, Chimeric Antigen Receptor (CAR) T cell-based cancer immunotherapy: A boon for cancer-free life, and Molecular insights and promise of Oncolytic Virus based Immunotherapy.

  • Bioquimica clinica

    Texto y atlas a color
    • 7th Edition
    • Michael Murphy + 2 more
    • Spanish
    Nueva ed. de esta obra de bioquímica que constituye un texto único y singular en la materia dentro de nuestro portfolio y que siempre ha mantenido el mismo abordaje: una obra visual, concisa, práctica y con un enfoque clínico. Es de destacar también el especial énfasis que se hace en la importancia de los test de laboratorio, su correcto diseño e interpretación de resultados para un correcto diagnóstico. Se mantiene su organización en 4 grandes secciones: Capítulos introductorios: Repaso de métodos y técnicas de laboratorio,Bioquími... Conceptos “core”, cubre todo el “bulk” de las pruebas bioquímicas más rutinarias y su relevancia clínica, Endocrinología: Proporciona una cobertura exhaustiva de los test bioquímicos realizados en el caso de patologías relativas a tiroides, hipófisis, glándulas adrenales, así como a las que afectan a las gónadas, siempre enfatizando su relevancia en la clínica e Investigaciones específicas: aquí se incluyen otros aspectos de pruebas y aspectos metabólicos. Cada uno de los capítulos tiene un diseño a doble página, con gran cantidad de elementos visuales, cuadros clínicos, casos, esquemas a todo color que lo convierten en “unidades didácticas” que incluso pueden estudiarse de forma individual. Las principales novedades de esta edición son la incorporación de 3 nuevos capítulos: Trastornos del páncreas, Métodos de inmunoensayo (anticuerpos.) y Métodos para la separación e identificación de moléculas. Así mismo, se han actualizado y renovado gran parte de las ilustraciones y esquemas y el número de casos clínicos que acompañan a algunos capítulos se han visto reforzados La nueva edición incluye acceso a contenido online en inglés a través de e-book+

  • Grapevine

    From Origin to the Vineyard
    • 1st Edition
    • Volume 110
    • English
    Advances in Botanical Research: From Origin to the Vineyard, Volume 110 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Grapevine origin and diversity, Climate change implications on the geography of viticulture, Canopy and soil management strategies insights into overcome abiotic stresses in grapevine, Grapevine defense mechanisms when challenged by pathogenic fungi and oomycetes, Management strategies for reducing pesticide use against diseases caused by fungi and oomycetes in grapevine, The Role of Plant Breeding in grapevine production, and New biotechnological tools for grapevine improvement.

  • Environmental Pollution and Type 2 Diabetes Mellitus

    • 1st Edition
    • Sultan Ayoub Meo
    • English
    Environmental Pollution and Type 2 Diabetes Mellitus elucidates on the global impact of environmental pollution and how it increases diabetes mellitus. Swift urbanization and the industrial revolution have increased environmental pollution to a hazardous level. Environmental pollution is a leading risk factor for several well-known diseases. This book opens venues for students, physicians, researchers, the science community, and policymakers to enhance their knowledge about environmental pollution, weather conditions, climate change, and their impact on insulin resistance and mechanisms allied to Type 2 diabetes mellitus (T2DM).Moreover, this book will provide knowledge about the green space environment and its impact on T2DM.

  • Current Omics Advancement in Plant Abiotic Stress Biology

    • 1st Edition
    • Deepesh Bhatt + 3 more
    • English
    Current Omics Advancement in Plant Abiotic Stress Biology investigates the causal molecular factors underlying the respective mechanisms orchestrated by plants to help alleviate abiotic stress. Despite available knowledge of abiotic stresses in crop plants and high throughput tools and biotechnologies, in this book, a systematic effort has been made for integrating omics interventions across major sorts of abiotic stresses with special emphasis to major food crops infused with detailed mechanistic understanding, which would furthermore help contribute in dissecting the interdisciplinary areas of omics-driven plant abiotic stress biology in a much better manner.It focuses on the integration of multi-OMICS biotechnologies in deciphering molecular intricacies of plant abiotic stress, namely drought, salt, cold, heat, and heavy metals in major C3 and C4 food crops. Together with this, the book provides updated knowledge of a common and unique set of molecular intricacies playing a vital role in coping up severe abiotic stresses in plants deploying multi-OMICS approaches.

  • Biocatalysis in Asymmetric Synthesis

    • 1st Edition
    • Gonzalo De Gonzalo + 1 more
    • English
    Biocatalysis in Asymmetric Synthesis, a new volume in the Foundations and Frontiers of Enzymology series, offers an applied discussion on synthesizing biological catalysts using asymmetric synthesis for varying applications. Here, global experts in the field analyze a wide variety of biocatalysts and their physical states, process conditions for their asymmetric synthesis, solvents required during synthesis, and even downstream procedures for the recovery of final products. The book adopts an interdisciplinary approach, merging fundamental biology and its synthetic applications across industries with a wide range of practical examples, from directed evolution to biotransformation and production of novel enzymes and non-conventional catalysts. Throughout the book, the impact and application of biocatalysis in sustainable processing is considered in-depth. This book will also help non-experts in biocatalysis to apply this knowledge in their own research, providing a thorough overview of the ways asymmetric biocatalytic approaches may be adapted for different disciplines and downstream products.

  • Integrative Omics

    Concept, Methodology, and Application
    • 1st Edition
    • Manish Kumar Gupta + 3 more
    • English
    Integrative Omics: Concept, Methodology and Application provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference provides systemic ‘step-by-step’ coverage that begins with basic concepts from Omic to Multi Integrative Omics approaches followed by applications and emerging and future trends. All areas of Omics are covered, including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics, technology policy, and society research. This book covers recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science.

  • Early and Late Presentation of Physical Changes of Puberty: Precocious and Delayed Puberty Revisited, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 53-2
    • Peter A. Lee + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Peter A. Lee and John S. Fuqua bring their considerable expertise to the topic of Precocious and Delayed Puberty Revisited. Top experts provide practical discussions of physical evidence of early or late pubertal development, offering a reasonable approach to patients presenting with these chief complaints.

  • Innovating Health Against Future Pandemics

    • 1st Edition
    • Simona Mellino + 3 more
    • English
    Innovating Health Against Future Pandemics covers the key aspects which drive heterogeneity in an individual's response to COVID-19, including age, sex, genetic makeup, immune responses, comorbidities, and viral strains/loads. This book also reviews the case examples from other disciplines to highlight areas where precision medicine and AI could be applied for the improvement of pandemic management. This includes research, primary and secondary prevention, isolation/tracking, hospitalization and patient management, diagnosis, and treatments. Lastly, drawing on past experiences for each of the areas this book provides practical recommendations to manage future pandemics.COVID-19 offered an unprecedented occasion to test the impact of digitally enabled solutions within precision medicine for public health and for accelerating their deployment and adoption.

  • Correlative Light and Electron Microscopy V

    • 1st Edition
    • Volume 187
    • Thomas Müller-Reichert + 1 more
    • English
    Correlative Light and Electron Microscopy V, Volume 187 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

  • Innovation in Anesthesiology

    Technology, Development, and Commercialization Handbook
    • 1st Edition
    • English
    Innovation in Anesthesiology: Technology, Development, and Commercialization Handbook reflects recent trends of industry globalization and value-conscious healthcare. Written by a team of leading anesthesiologists, engineering development professionals, business analysts, commercialization experts, regulatory and reimbursement specialists, and legal authorities, this volume in the Clinical and Medical Innovation series provides a clear process for the identifi cation, invention, and implementation of new solutions in anesthesiology. This is the ideal resource for anesthesiology innovators who desire to deliver patient solutions and applications to their inventions. Featured case studies on innovative products highlighting the stages required are included for reference.The book will lead researchers, clinicians, entrepreneurs, and investors through a clear process for the identification, invention, and implementation of new clinical technology solutions. Expert medical device inventor/entrepreneu... provide case studies on globally innovative products including successes, failures and practical advice. The book will be a key reference for entrepreneurs developing emerging technology in anesthesia, investors funding innovation in anesthesia, life science business leaders seeking to understand market trends in technology development, tech transfer offices determining prioritization of patenting dollars, distributors seeking to understand trends in anesthesia technology, as well as researchers and engineers seeking to understand market development needs and trends.

  • Reproducibility in Biomedical Research

    Epistemological and Statistical Problems and the Future
    • 2nd Edition
    • Erwin B. Montgomery Jr.
    • English
    Reproducibility in Biomedical Research: Epistemological and Statistical Problems, Second Edition explores the ideas and conundrums inherent in scientific research. This second edition addresses new challenges to reproducibility in biosciences, namely reproducibility of machine learning Artificial Intelligence (AI), reproducibility of translation from research to medical care, and the fundamental challenges to reproducibility. All current chapters are expanded to cover advances in the topics previously addressed. This book provides biomedical researchers with a framework to better understand the reproducibility challenges in the area. Newly introduced interactive exercises and updated case studies help students understand the fundamental concepts involved in the area.

  • Carbon-Based Nanomaterials in Biosystems

    Biophysical Interface at Lower Dimensions
    • 1st Edition
    • Kunal Biswas + 3 more
    • English
    Carbon-Based Nanomaterials in Biosystems: Biophysical interface at Lower Dimensions provides a thoroughly comprehensive overview of all major aspects of carbon-based nanomaterials, their biophysical response, and biotechnological applications. The book articulates the underlying physics, chemistry, and the basic phenomenon of the broad-range carbon-based nanomaterials (CNMs) with biological systems, particularly the interface analysis. Organized in six sections, it discusses state-of art technological interventions of carbon-based nanomaterials and their application in biomedical sectors in healthcare, food sciences, and technology. The book also highlights the carrying capacity of different CNMs in payload efficiency mechanisms in various biomedical fields. The theranostic efficiency and the safety of various forms of CNMs is assessed. This book will be a helpful resource to those specializing in the areas of nanomedicine, bionanomaterials, and nanotechnology applications.

  • Primate Anatomy

    Introduction to Extant Primates
    • 4th Edition
    • Friderun Ankel-Simons
    • English
    Primate Anatomy: Introduction to Extant Primates synthesizes the taxonomy, anatomy, physiology, and genomics of extant primates, including humans. It takes a holistic approach to describing primate skeletal, muscular, and organ structure and function, providing the tools to understanding the fundamentals and state of the science of primatology. Now in its fourth edition, this work introduces its audience to the history and objectives of the field of primatology. It enumerates and profiles extant primates before delving into detailed descriptions of primate skulls, brains, teeth, skeletons, musculature, organs, blood groups, reproduction, and development.In addition, the book highlights recent advances in primate genomics, including new genera and species assignments, and concludes with a glance at the future of the field. Written by longtime expert Friderun Ankel-Simons, this new edition effectively introduces complex biological concepts in a manner accessible to all readers. It will serve as an excellent reference for technical and non-technical audiences, including primatologists, anatomists, paleontologists, anthropologists, conservationists, and naturalists.

  • Advances in Cytometry: Applications

    • 1st Edition
    • Volume 186
    • English
    Advances in Cytometry: Applications, Volume 176 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

  • Targeting Signaling Pathways in Solid Tumors Part A

    • 1st Edition
    • Volume 385
    • English
    Targeting Signaling Pathways in Solid Tumors, Part A, Volume 385 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more.Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled

  • Applications of Metagenomics

    Agriculture, Environment, and Health
    • 1st Edition
    • Hrudayanath Thatoi + 2 more
    • English
    Applications of Metagenomics: Agriculture, Environment, and Health examines current metagenomics methods and their applications in soil, polluted environment sites, agriculture production, and health care, with separate sections dedicated to each application area. Special attention is paid to the biotechnological study of novel microbial resources for social welfare. Beyond applications, the book discusses evolving next generation technology and techniques used for carrying out metagenomics studies, and in doing so highlights the latest research and advances in the field, along with ways to adapt these approaches for different study types across the biological sciences.Chapter topics range from metagenomics for studying root microbial communities to microbial diversity of the rhizosphere, fungal diversity, microbial biodiversity in forest environments, the human microbiome, and disease epidemiology, with one chapter dedicated to Covid-19 metagenomics.

  • Introduction to Protein Mass Spectrometry

    • 2nd Edition
    • Pradip K. Ghosh
    • English
    Introduction to Protein Mass Spectrometry, Second Edition provides a comprehensive overview of this increasingly important, yet complex, analytical technique. This book enables readers to understand how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. This new edition is fully updated to include the latest developments in the field and will feature new content covering recent progress in the areas where there have been the most exciting advances. These include PNNL’s multilevel-PCB-based SLIM realization, SLIM-Agilent QQQ field trials; employment of SLIM-IMS-cryo-IR combination in molecular structure determination; proximity-labelling mass spectrometry, and applications in neuroscience.

  • The Covid-19 Response in New York City

    Crisis Management in the Epicenter of the Epicenter
    • 1st Edition
    • Syra S. Madad + 2 more
    • English
    The COVID-19 Response in New York City: Crisis Management in the Largest Public Health System provides an historical accounting of the response to the COVID-19 pandemic through the eyes of the largest public health system in the United States. The book offers a roadmap to guide healthcare systems and their providers in the event of future pandemics. Readers will learn about surge staffing and level loading, as well as tips from the ED and ICUs on how to respond to an unprecedented influx of inpatients. Written by healthcare providers who were at the epicenter of the pandemic in New York City, this book provides a sound accounting of the response to the pandemic in one of the world's largest cities.

  • Regenerative Medicine in the Genitourinary System

    • 1st Edition
    • Farshid Sefat + 1 more
    • English
    Regenerative Medicine in the Genitourinary System gives the reader a comprehensive overview of tissue engineering used to treat genitourinary disorders and infertility, also providing a great learning platform for researchers in different fields such as cell biology, pharmaceutics, clinicians, chemists, material scientists, and more. The book covers the latest innovations on the subject, but also acts as a resource for tissue engineering applications and regenerative medicine. Over the last several decades, tissue engineering has continued to make considerable advancements in therapeutic and clinical strategies that address male/female urological or genitourinary diseases.Although several articles have been published on this topic, there are very few book chapters and no single book currently available dedicated to this topic.

  • Fluorine Metabolism, Transport and Enzymatic Chemistry

    • 1st Edition
    • Volume 696
    • English
    Fluorine Metabolism, Transport and Enzymatic Chemistry, Volume 696 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Fluorine Metabolism, Transport, and Enzymatic Chemistry. Chapters in this new release include Determination of fluoride sensitivity and resistance in oral biofilm models, NMR methods to detect fluoride binding and transport by membrane proteins, Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans, Measurement of fluoride efflux from lipid vesicles and cells, Defluorination of PFAS by Acidimicrobium sp. A6 and Potential Applications for Remediation, and more.Additional chapters cover Computational approaches to investigate F- binding, selectivity and transport in F- exporters, Defluorination as a key trait to gauge the biodegradability of fluorinated pollutants: challenges and opportunities, Patch-Clamp Electrophysiology of Fluoride Channels in Saccharomyces cerevisiae, and Synthesis of fluorophenylalanine-... proteins in HEK cells.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 126
    • English
    Advances in Applied Microbiology, Volume 126 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Overview of Inflammatory Breast Cancer: Updates

    • 1st Edition
    • Volume 384
    • English
    International Review of Cell and Molecular Biology, Volume 381 highlights new advances in the field, with this new volume presenting interesting topic on Overview of Inflammatory Breast Cancer: Updates.

  • Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling

    From Lab Bench Work to its Clinical Perspective
    • 1st Edition
    • Asim K. Duttaroy + 1 more
    • English
    Cellular, Molecular and Environmental Contribution in Cardiac Remodeling consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. The book extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise, and more.It provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, along with its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed.

  • Translational Orthopedics

    • 1st Edition
    • Jeffrey A. Bakal + 4 more
    • English
    Translational Orthopedics: Designing and Conducting Translational Research covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational orthopedics, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts.The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational orthopedics, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every Medical Researcher or Orthopedist who has ever had a good clinical idea but not the knowledge of how to test it.

  • Antioxidant Methods

    A Guideline for Understanding and Determining Antioxidant Capacity
    • 1st Edition
    • Francisco Avelino
    • English
    Antioxidant Methods: A Guideline for Understanding and Determining AntioxidantCapacity summarizes the importance of antioxidants as a class of compounds withinnumerous areas of science and technology. The chapters elucidate diverse methodologiesfor assessing the antioxidant capacity of an antioxidant, while also exploring the correlationbetween its structural attributes and overall performance. Chapters include descriptions ofprotocols used to measure antioxidant capacity by different methods, highlighting experimentalsteps, bottlenecks, expected outcomes, advantages, limitations, and more.This is the perfect reference for biomedical science researchers looking for the right methodfor determining antioxidant capacity through the structure and functionalities of the compound,as well as the mechanisms involved in the antioxidant action.

  • Sinusoidal Cells in Liver Diseases

    Role in their Pathophysiology, Diagnosis, and Treatment
    • 1st Edition
    • Jordi Gracia-Sancho
    • English
    Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers, and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics.Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

  • Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics

    • 1st Edition
    • Ting-Chao Chou
    • English
    “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” provides a comprehensive overview and update of the mass-action law-based unified dose-effect biodynamics, pharmacodynamics, bioinformatics, and the combination index theorem for synergy definition (MAL-BD/PD/BI/CI). Contents advocate the fundamental MAL-PD/BI/CI/BI principle for biomedical R&D, clinical trials protocol design computerized data analysis, illustrates the MAL-dynamics theory with sample analysis, and includes data entry and automated computer report print-outs. In 11 sections “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” leads the reader from an introduction and overview, to trial protocols and MAL-PD/CI approach for biomedical R&D in vitro and in animals. It describes the current Landscape of International FDA Drug Evaluation, Clinical Pharmacology, and Clinical Trials Guidance. This is a valuable resource for biomedical researchers, healthcare professionals, and students seeking to harness the power of data informatics in precision medicine.

  • Pathophysiology, Risk Factors, and Management of Chronic Heart Failure

    • 1st Edition
    • Ram B. Singh + 3 more
    • English
    Chronic Heart Failure: Pathophysiology, Risk Factors, and Mechanisms aims to provide an inclusive overview on Chronic Heart Failure (CHF).This book is focused on the epidemiology, classification, molecular mechanisms, pathophysiology, causes, identification and interactions of heart failure. It will explain the uncertainties and issues in Heart Failure by helping readers understand the physiopathology of CHF in the light of behavioural risk factors. 2D and 3D speckle tracking echocardiography have been used to quantify regional alterations of longitudinal strain and area strain, through their polar projection, which allows a further evaluation of both the site and extent of myocardial damage. The analysis of strain can identify subclinical cardiac failure (myocyte remodelling) which is a major issue in CHF. Myocardial Strain, measure by speckle tracking echocardiography, is frequently attenuated in these conditions and can be utilized for the evaluation of disease progression and the effect of therapeutic interventions as well as prevention because it could be a manifestation of behavioural risk factors.This title will function as an essential reference to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agents, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF.

  • Techniques for Biochemical Analysis

    • 1st Edition
    • Khursheed Hussain + 3 more
    • English
    Techniques for Biochemical Analysis provides researchers with a practical guide for investigating a variety of different biomolecules. It includes a range of tried and tested protocols, outlining the principles upon which each technique is founded, as well as providing instructions on equipment setup and use, buffer preparation, reagents required, safety considerations and analysis of findings. Beginning with an introduction to biochemistry and laboratory procedures, the book moves on to specific methods focused on investigation of carbohydrates, proteins, enzymes, plant hormones, minerals, amino acids, and more.The large range of protocols covered in this foundational, how-to reference are interdisciplinary and adaptable to a variety of areas, making this an ideal resource for researchers across various fields, including biochemistry, molecular biology, medical sciences, plant physiology, agriculture, and related subjects.

  • COVID-19’s Consequences on the Cardiovascular System

    Immediate, Intermediate, and Long-Term Complications
    • 1st Edition
    • Fabian Sanchis-Gomar + 1 more
    • English
    Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system; its most common complications are arrhythmia, cardiac injury, fulminant myocarditis, heart failure, and pulmonary embolism. COVID-19’s Consequences on the Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all aspects related to the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications.Writte... by a team of experts, this book is a one-stop-shop reference for healthcare professionals and researchers who require a comprehensive view of the deleterious effects of COVID-19 on the cardiovascular system. It discusses the relationship of cardiovascular risk factors with COVID-19 prognosis. It offers further insights into the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level.

  • Fundamental Principles of Oxidative Stress in Metabolism and Reproduction

    Prevention and Management
    • 1st Edition
    • Faiza Alam + 1 more
    • English
    Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management is a comprehensive resource for anyone needing awareness and recognition of oxidative stress as a basic component of disease to determine the precise treatment plan considering the cause of the disease. It describes the effects of oxidative stress in the human body, the detection of metabolic changes, psychological impact and effect on reproductive outcomes. In addition, it discusses alterations at the cellular level occurring due to oxidative stress along with the genetic aspects involved in its pathogenesis.

  • Exosomal RNA

    Role in Human Diseases and Therapy
    • 1st Edition
    • Debalina Bhattacharya + 2 more
    • English
    Exosomal RNA: Role in Human Diseases and Therapy provides an in-depth study of exosomes and their RNA in the context of a variety of diseases. The book explores the diagnostic and therapeutic potential of exosomal RNA as biomarkers across a range of different conditions, including cancer, type 2 diabetes, cardiovascular and renal disease, as well as bacterial infections and tissue repair. The link between exosomal RNA expression and neurodegenerative disease is also explored. The book goes on to share the significance of exosomal RNA in preserving cellular function, with special attention given to their role in the autophagy process.This book also gives an overview of the isolation, characterization, and potential applications of exosomal RNA, providing researchers with an understanding of how they can be manipulated and utilized for the treatment of various diseases and conditions. This is an ideal reference for researchers in the field of molecular biology, cell biology, and related fields, as well as those involved in the development of therapeutics and personalized medicine.

  • Animal Models of Disease Part A

    • 1st Edition
    • Volume 185
    • English
    Animal Models of Disease, Part A, Volume 185 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including New mouse model to study aneurysm development, Mouse Model of Secondary Cystic Echinococcosis, Modelling childhood cancer in Drosophila, Analysis of immunohistomorpholog... changes in the colonic mucosa in a high-saturated fat and high-cholesterol fed streptozotocin/nicot... diabetic rat model, Establishment of an orthotopic Glioblastoma mouse model for preclinical studies, Lateral Fluid Percussion Injury as a Model for Traumatic Brain Injury, Ovarian and colorectal peritoneal carcinomatosis in mouse models, and more.Other chapters cover Genetically engineered mouse model of hepatocellular carcinoma, Radiotherapy protocol in cancer mouse models, Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation, Methodology for the induction of myocardial infarction and cardiac function evaluation, Behavioral assessment of fine socio-sexual olfactory cues detection in a mouse model of neurodegeneration, Heat shock and thermotolerance in Caenorhabditis elegans: an overview of laboratory techniques, and Using the model cestode Taenia crassiceps for the study of cysticercosis.

  • A Multidisciplinary Approach to Managing Swallowing Dysfunction in Older People

    • 1st Edition
    • Pere Clave´ + 1 more
    • English
    A Multidisciplinary Approach to Managing Swallowing Dysfunction in Older People provides comprehensive coverage on oropharyngeal dysphagia (OD), focusing on older patient phenotypes. The book provides the knowledge needed for translational researchers and professionals to aid in the detection, diagnosis, treatment and management of OD, ultimately improving patient quality of life. OD has been recently considered a geriatric syndrome because of its high prevalence, the increase of life-expectancy and the need to be managed by a multidisciplinary approach. This reference takes a novel approach to OD, covering all aspects as a geriatric syndrome, examining a complicated and multi-level topic in a succinct way. Contents include the most innovative information available in current literature combined with practical applications to improve the diagnosis and treatments of OD as a geriatric syndrome. This is the perfect reference for translational researchers, physicians and healthcare professionals dealing with OD.

  • Microbial Diversity in the Genomic Era

    Functional Diversity and Community Analysis
    • 2nd Edition
    • Surajit Das + 1 more
    • English
    Microbial Diversity in the Genomic Era: Functional Diversity and Community Analysis, Second Edition presents techniques used for microbial taxonomy and phylogeny, along with their applications and respective strengths and challenges. The book incorporates recently developed biosystematics methods and approaches to assess microbial taxonomy, with suitable recommendations for where to apply them across the range of bacterial identification and infectious disease research. Sections provide a broad overview of microbial genomics research and microbiome directed medicine and update on molecular tools for microbial diversity research, extremophilic microbial diversity, functional microbial diversity across application areas, microbial diversity and infectious disease research, and future directions. Step-by-step methodologies are provided for key techniques, along with applied case studies that break down recent research studies into practical components, thus illuminating pathways for new studies across the field.

  • Anoxygenic Phototrophic Bacteria

    • 1st Edition
    • Keizo Shimada + 1 more
    • English
    Anoxygenic Phototrophic Bacteria is a comprehensive overview of phototrophic bacteriacovering the following: overview of photosynthesis and phototrophic bacteria; systematicsand characteristics of each taxon; ecology and cultivation; photosynthetic electrontransfer systems; metabolism; pigments and lipids; light-harvesting systems and reactioncenters; photosynthetic genes and regulation of gene expression; origin and evolution ofphotosynthesis; and the utilization of phototrophic bacteria.Chapters are written by some of Japan’s leading researchers in the area, providing researchersin photosynthesis, bacterial physiology, microbial ecology, artificial photosynthesis,bioph... biochemistry, industrial chemistry a highly detailed, up-to-date and thoroughlycross-refe... book in this interdisciplinary area. With very few books being published overthe last 25 years on the topic, this book especially fills a crucial need for young researchersand those working at the margins of interdisciplinary fields.

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