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Elsevier

Books in Clinical endocrinology

  • The Plasticity of Sex

    The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior
    • 2nd Edition
    • Marianne Legato J
    • English
    The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior, Second Edition offers a thorough exploration of the biological, clinical, and social dimensions of human sexuality. This updated edition emphasizes the increasing recognition of the diversity of sexual identities and behaviors, particularly the spectrum between traditional male and female categories. It consolidates evidence-based research on the molecular and developmental biology of sex, gender identity, and sexual behavior, presenting a comprehensive resource for biomedical researchers, clinicians, and medical students. A key theme of this edition is the growing understanding of human sexuality as fluid and diverse, shaped by a variety of genetic, hormonal, and environmental factors. Over recent decades, there has been heightened interest in issues like gender identity, genital ambivalence, and sexual transition, with both the general public and medical professionals seeking more knowledge and guidance on these topics. The book underscores the need for a more inclusive approach, incorporating voices from diverse communities and recognizing the importance of broadening the scope of research beyond narrow sample sizes and traditional binary frameworks. The new edition highlights the ongoing challenges in understanding and addressing variations in human sexuality and the need for continued dialogue between science, society, and legal systems to create more inclusive frameworks for care and support. This work serves as an essential reference for anyone involved in the study or treatment of human sexuality.

  • Congenital Adrenal Hyperplasia

    A Comprehensive Guide
    • 2nd Edition
    • Peter C. Hindmarsh + 1 more
    • English
    Congenital Adrenal Hyperplasia: A Comprehensive Guide, Second Edition provides a fully-illustrated edition that outlines the basics of CAH and its interrelation with hormones and bodily function, including updated content on the latest clinical research. A new chapter dedicated to gene therapy covers principles, current status, the latest research developments, and potential treatments for congenital adrenal hyperplasia. In addition, this new release updates patient profiles due to several new clinical studies in CAH for improved condition management, with practical information on how to deal with emergencies, medic alert emergency kits, emergency injection needles, handling illness, surgery, and more.In addition, new assays are incorporated for the analysis of pituitary and adrenal hormones for the determination of the disease. This new edition continues to be a vital reference to pediatric endocrinologists as well as primary care providers to help affected patients with an updated model of care and appropriate treatment. Patients and family members will continue to benefit from the new trend-forward information presented and will be empowered to approach their health care providers with the expectation of receiving individualized care and treatment of the disorder.

  • Cushing Syndrome

    History, Diagnosis and Treatment
    • 1st Edition
    • Constantine A. Stratakis
    • English
    Cushing Syndrome: History, Diagnosis, and Treatment is written by top experts on the latest in genetics, molecular advances, and the diagnosis and treatment of Cushing syndrome. The book takes a historical approach to discuss the tremendous and unprecedented research development for this rare condition and includes information on recently approved treatments. It attempts to provide information on most issues surrounding Cushing syndrome and how to deal with its complications, the widening understanding of functional hypercortisolemia and other causes of endogenous cortisol production and its old and new treatment modalities, from pituitary to adrenal tumors, ectopic ACTH production, subclinical, cyclical Cushing syndrome, to aging and metabolic syndrome.The book has a section dedicated to our patients with the patients’ experiences, which will add to the outcome research presented by the physicians. This is a must have reference for scientists and researchers with the latest information in diagnosing and treating this difficult-to-diagnos... and difficult-to-treat condition and gives the clinician, a patient-centric approach to communicate with this particular group of patients.

  • How Sex and Gender Impact Clinical Practice

    An Evidence-Based Guide to Patient Care
    • 2nd Edition
    • Marjorie R. Jenkins + 1 more
    • English
    How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, is an essential resource for primary care clinicians seeking to integrate sex and gender differences into their practice. This edition emphasizes the unique framework that assists practitioners in providing personalized care. It aligns sex and gender medicine with precision medicine, helping healthcare providers attract patients who value clinicians that understand the nuances of sex and gender in healthcare.How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, includes updates on the evidence-based information on disease prevalence, diagnosis, testing, and treatment, as well as a new chapter on the sex and gender aspects of pain. Each chapter reflects how sex and gender impact disease presentation, physical examination, testing, treatment, and clinical decision-making.

  • Chronic Complications of Diabetes Mellitus

    Current Outlook and Novel Pathophysiological Insights
    • 1st Edition
    • Didac Mauricio + 1 more
    • English
    Chronic Complications of Diabetes Mellitus: Current Outlook and Novel Pathophysiological Insights provides a holistic view of the disease, discussing not only its classical complications but also the under recognized and managed conditions associated with diabetes. Chapters also discuss advances in our understanding of the genomic architecture of diabetes complications and how precision medicine can be used to personalize their management. Endocrinologists, diabetologists, primary care physicians and researchers interested in complications of diabetes mellitus and cutting-edge information will find this to be a comprehensive tome on the topic. Diabetes complications include pathological changes usually related to the vascular system and classical target organs. However, there are also nonclassical complications independent or partially independent from vascular damage that are often overlooked.

  • Handbook of Obesity in Obstetrics and Gynecology

    • 1st Edition
    • Tahir A. Mahmood + 1 more
    • English
    **Selected for 2026 Doody's Core Titles in Obstetrics & Gynecology**Handbook of Obesity in Obstetrics and Gynecology addresses all aspects of general obstetrics and gynecology in obese patients, providing evidence-based guidance for the treatment and management of gynecological problems and pregnancy-related care in obese women. The book is a valuable resource for junior doctors, residents and obstetricians and gynecologists looking for a comprehensive guide that addresses the most relevant aspects of obstetric and gynecologic care that are impacted by obesity, an increasingly prevalent condition. The rising prevalence of global obesity is of public health concern, hence obese women suffer from a higher incidence of menstrual disorders, polycystic ovaries, infertility issues, and more.In pregnancy, obesity is associated with an increased risk of early pregnancy loss, recurrent pregnancy loss, fetal developmental abnormalities, thrombo-embolic disease, gestational diabetes, dysfunctional labor, post-partum hemorrhage and difficult operative deliveries.

  • Principles and Practice of Ovarian Tissue Cryopreservation and Transplantation

    • 1st Edition
    • Kutluk Oktay
    • English
    Principles and Practice of Ovarian Tissue Cryopreservation and Transplantation provides methods and techniques of ovarian tissue harvesting and cryopreservation, including instructional videos. This book will benefit a wide audience, guiding infertility specialists, fellows, residents, reproductive surgeons, reproductive endocrinologists, pediatric surgeons, embryologists, infertility nurses and gynecologists. Ovarian cryopreservation and transplantation is rapidly gaining acceptance as a successful and established fertility preservation strategy in cancer patients and beyond. Unlike other fertility preservation strategies, it can be performed in children as well as adults, and can be helpful in restoring natural ovarian function and fertility, hence this is a welcomed resource on the topic.

  • Chesley's Hypertensive Disorders in Pregnancy

    • 5th Edition
    • Robert N. Taylor + 4 more
    • English
    Leon Chesley’s Hypertensive Disorders in Pregnancy was initially published in 1978. Four decades later, hypertension complications in pregnancy are still a major cause of fetal and maternal morbidity and death, especially in less developed nations. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this, hypertensive disorders remain marginally studied and management is often controversial. Chesley’s Hypertensive Disorders in Pregnancy, Fifth Edition continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. This revision focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. It provides a superb analysis of the multiple topics that relate to hypertension in pregnancy, especially of preeclampsia.

  • Gigantism and Acromegaly

    • 1st Edition
    • Constantine A. Stratakis
    • English
    Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies.

  • Goodman's Basic Medical Endocrinology

    • 5th Edition
    • Elizabeth H. Holt + 4 more
    • English
    Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study.

  • The Plasticity of Sex

    The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior
    • 1st Edition
    • Marianne Legato J
    • English
    The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior provides a comprehensive view on the development of human sexuality. As there has been a crescendo of interest over the past several decades about the nature and diversity of human sexuality, this reference brings the evidence-based research into one place. The emergence of issues surrounding gender identity, genital ambivalence and the transition from one sex to another is striking, with the public and treating physicians alike clamoring for an evidence-based, comprehensive treatment of human sexuality and all its variations. This is a must-have reference for biomedical researchers in endocrinology, neuroscience, development biology, medical students, residents, and practicing physicians from all medical areas. Winner of the 2021 PROSE Award in Biomedicine from the Association of American Publishers!

  • Biomarkers in Inborn Errors of Metabolism

    Clinical Aspects and Laboratory Determination
    • 1st Edition
    • Uttam Garg + 1 more
    • English
    Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future.

  • Congenital Adrenal Hyperplasia

    A Comprehensive Guide
    • 1st Edition
    • Peter C. Hindmarsh + 1 more
    • English
    Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important. The book provides an in-depth analysis of this disorder for pediatric endocrinologists and primary care providers, allowing them to help patients with an updated model of care and appropriate treatment. Patients and family members will benefit from the trend-forward information that will empower them to approach their healthcare providers with the expectation of receiving individualized care and treatment for this disorder.

  • Cushing's Disease

    An Often Misdiagnosed and Not So Rare Disorder
    • 1st Edition
    • Edward R. Laws Jr + 1 more
    • English
    Cushing’s Disease: An Often Misdiagnosed and Not So Rare Disorder reviews the epidemiology of Cushing’s, including statistics on the incidence and prevalence of this disease. There are discussions of the signs and symptoms and the most common co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, amenorrhea, and infertility. Surgical, medical, and radiotherapeutic treatments, including indications, results, risks, and complications, are reviewed. Also featured is a chapter on the patient’s perspective, coping with Cushing’s, quality of life, and psychosomatic issues. This book is essential reading for the wide range of physicians who treat patients with Cushing’s disease symptoms, as well as biomedical researchers who investigate the etiology and mechanisms of rare genetic diseases, in particular rare endocrine disorders.

  • Endocrinology of the Heart in Health and Disease

    Integrated, Cellular, and Molecular Endocrinology of the Heart
    • 1st Edition
    • Jonathan C. Schisler + 2 more
    • English
    Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology... the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology.

  • Advances in Pathobiology and Management of Paget’s Disease of Bone

    • 1st Edition
    • Sakamuri V. Reddy
    • English
    Advances in Pathobiology and Management of Paget’s Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget’s disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget’s disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease.

  • The Protective Arm of the Renin Angiotensin System (RAS)

    Functional Aspects and Therapeutic Implications
    • 1st Edition
    • Thomas Unger + 2 more
    • English
    The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications.

  • The Parathyroids

    Basic and Clinical Concepts
    • 3rd Edition
    • John P. Bilezikian + 5 more
    • English
    The third edition of The Parathyroids, led by a new stellar editorial team, has been thoroughly updated to reflect the considerable advances in just about every aspect of PTH biology over the past decade. It continues to be the authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium. This translational resource is invaluable to graduate students, fellows, researchers, and research clinicians in the fields of endocrinology, bone biology, osteology, and rheumatology.

  • Clinical Neuroendocrinology

    • 1st Edition
    • Volume 124
    • Eric Fliers + 2 more
    • English
    Clinical Neuroendocrinology, a volume in the Handbook of Clinical Neurology Series gives an overview of the current knowledge in the field of clinical neuroendocrinology. It focuses on the pathophysiology, diagnosis, and treatment of diseases of the hypothalamus and the pituitary gland. It integrates a large number of medical disciplines, including clinical endocrinology, pediatrics, neurosurgery, neuroradiology, clinical genetics, and radiotherapy. Psychological consequences of various disorders and therapies, as well as therapeutic controversies, are discussed. It is the first textbook in the field to address all these aspects by a range of international experts.

  • Diabetes

    Oxidative Stress and Dietary Antioxidants
    • 1st Edition
    • Victor R. Preedy
    • English
    Diabetes: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide among diabetologists, endocrinologists, and nutritionists in understanding and treating diabetes. The book covers, in a single volume, the science of oxidative stress in diabetes and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, receptor-mediated responses and more. This approach recognizes that diseases are usually multifactorial and that oxidative stress is a single component of this.Pharmacological treatments for diabetes are commonly marked by unwanted side effects, leading to treatment efforts using naturally occurring substances. But a plant-based approach alone is not sufficient; understanding the processes inherent in the oxidative stress of diabetes is vital for clinical workers, dietitians, and nutritionists.This translational work provides that understanding. The book begins by covering the basic biology of oxidative stress from molecular biology to imaging in relation to diabetes. There are chapters on neuropathy, nephropathy, atherosclerosis, cardiomyopathy, and retinopathy. The book then moves on to antioxidants in foods, including plants, components of the diet, and their relevance to diabetes.

  • Recent Progress in Hormone Research

    Proceedings of the 1966 Laurentian Hormone Conference
    • 1st Edition
    • Gregory Pincus
    • English
    Recent Progress in Hormone Research, Volume 23 is a collection of papers presented at the 1966 Laurentian Hormone Conference, held at Mont Tremblant, Quebec, Canada. This conference explores four major areas of research, including thyroid physiology, thyroid hormones, contemporary developments in peptide hormone chemistry and biochemistry, and special studies of insulin, particularly in man. This book is organized into four parts encompassing 14 chapters. Part I deal with the factors controlling thyroid stimulation and special studies of the mode of action of thyroid hormones, including antithyroid drugs. Part II describes the mode of action of steroid hormones and hormonal steroids based on the effects on normal and neoplastic tissues. This part also looks into a definitive segment of research in endocrinology with the metabolism of the steroid hormones in vivo and in vitro. The discussion of an important clinical condition involving adrenocortical steroid production is given in the chapter concerned with congenital adrenal hyperplasia. Parts III and IV explore the synthesis of peptide hormones and insulin. These parts also tackle the gastrointestinal hormone biochemistry, the detection of at least two insulin-like activities in human serum, and the particular control of insulin activity in man. This book is directed primarily toward endocrinologists.

  • Recent Progress in Hormone Research

    Proceedings of the 1985 Laurentian Hormone Conference
    • 1st Edition
    • Roy O. Greep
    • English
    Recent Progress in Hormone Research, Volume 42 covers the proceedings of the Laurentian Hormone Conference held on September 1985 in Banff, Alberta, Canada. The book presents developments in research on important topics such as chemical neuroanatomy of the brain based on the histochemistry of brain neuronal transmitters and peptides; the hormonal regulation of gene transcription and expression; and steroid hormone receptors and their action. The text also includes papers on the atrial naturietic factor; the fibroblast growth factor; and the neuroendocrinology of puberty in rodents, seasonal breeders, and humans. Papers on the comparative endocrinology including studies on marsupials, teleosts, and microorganisms; and parathyroid hormone, bioactive forms, gene expression, and malignancy-associate... hypercalcemia are also encompassed. Endocrinologists, physiologists, biochemists, and scientists involved in hormone research will find the book invaluable.

  • Recent Progress in Hormone Research

    Proceedings of the 1983 Laurentian Hormone Conference
    • 1st Edition
    • Roy O. Greep
    • English
    Recent Progress in Hormone Research, Volume 40 presents the proceedings of the 1983 Laurentian Hormone Conference held in Mont Tremblant, Canada. The book presents papers on promoter elements of genes coding for proteins and modulation of transcription by estrogens and progesterone; the structure, expression, and evolution of the genes for the human glycoprotein hormones; and the regulation and organization of thyroid stimulating hormone genes. The text also includes papers on the mouse mammary tumor virus model in studies of glucocorticoid regulation; the role of the circadian system in reproductive phenomena; and endocytosis and membrane traffic in cultured cells. Other papers on neuroendocrinology, mechanism of hormone action, reproductive biology, subcellular processing of hormones and their receptors, hereditary resistance to 1,25-dihydroxyvitami... D are also encompassed. Physiologists, endocrinologists, biochemists, and scientists involved in hormone research will prove the book invaluable.

  • Hormones and Human Breast Cancer

    An Account of 15 Years Study
    • 1st Edition
    • John Hayward
    • V. G. Allfrey + 2 more
    • English
    Recent Results in Cancer Research: Hormones and Human Breast Cancer provides information pertinent to the fundamental aspects of breast cancer and hormones. This book discusses the endocrine factors involved in breast cancer. Organized into two parts encompassing 11 chapters, this book begins with an overview of the process of castration as an effective therapeutic measure in many pre-menopausal patients with advanced breast cancer. This text then discusses the response rate following ablation wherein only 60 percent of patients subjected to hormone therapy as a first treatment for recurrence will survive to ablation. Other chapters consider the microscopical features of a tumor. This book discusses as well the prescription of corticosteroids as treatment, which originates from the mechanism of response that followed adrenalectomy or hypophysectomy. The final chapter deals with the use of radio-immunoassay methods in treating breast cancer. This book is a valuable resource for biochemists, scientists, and physicians.

  • Hormones and the Fetus

    Volume 1: Production, Concentration and Metabolism During Pregnancy
    • 1st Edition
    • F. A. Kincl + 1 more
    • English
    Written by the world's two leading researchers in steroid biochemistry this volume describes the ways in which hormonal concentration is regulated during pregnancy. It is a comprehensive account of how biosynthesis, metabolism and inter-compartmental transport are related to the concentration of each hormone found in placental, fetal and maternal compartments. There is also an introductory chapter on hormonal mechanism of action.

  • Hormones and the Fetus

    • 1st Edition
    • J. R. Pasqualini + 2 more
    • English
    Volume One of Hormones and the Fetus contained a generalization of the role of hormones during fetal life. In this second volume, the main topics focus on hormonal binding to fetal and maternal plasma proteins, amniotic fluid and placenta; the presence of hormone receptors in the fetal compartment; and the mechanism of action of various hormones in different target tissues of the fetus and placenta. This up-to-date information is of major importance in the study of hormonal activity in fetal life, and the biological effect of hormones through the receptor. The mechanism of fetal sexual differentiation, in which hormones play an important role, is extensively covered.

  • Progress in Medical Genetics

    Volume 5
    • 1st Edition
    • Arthur G. Steinberg + 1 more
    • English
    Progress in Medical Genetics: Volume 5 covers the improvements in nutrition and control of childhood disease. This book is divided into five chapters that evaluate the characteristics of thalassemias, an inherited defect in hemoglobin. It addresses the genetic control of hemoglobin synthesis and the clinical pictures and nomenclature of the different porphyrias. Some of the topics covered in the book are the genetic aspects of liver disease connected with jaundice; development of the concept of thalassemia as a hemoglobinopathy; bilirubin metabolism; description of hemolytic jaundice; description of hyperbilirubinemia. The succeeding chapters describe the disturbances in bilirubin uptake and conjugation, as well as the clinical diagnosis of familial non-hemolytic hyperbilirubinemias. An analysis of the Dubin-Johnson and Rotor syndrome is provided. The last chapters consider the genetics of muscular and the analysis of autosomal dominant forms of muscular dystrophy. The book can provide useful information to doctors, endocrinologists, students, and researchers.

  • Hormones and Breast Cancer

    • 1st Edition
    • Volume 93
    • English
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on hormones and breast cancer.

  • Practical Pediatric Endocrinology in a Limited Resource Setting

    • 1st Edition
    • Margaret Zacharin
    • English
    Practical Pediatric Endocrinology in a Limited Resource Setting provides a guide for managing pediatric endocrine problems in a limited resource setting, together with an outline of the bases for these disorders. The book outlines a plan for coming to a likely diagnosis in situations where resources are constrained, and suggests ways to access more sophisticated technologies for diagnostic confirmation and extension of available tools. Further extending and complementing each chapter is a series of scenarios for use as teaching and learning tools. Together with a clinical question, all chapters include a suggested outline for assessment that assists readers facing similar situations in daily practice. Each scenario works through a typical series of deductive steps used to establish a working diagnosis, while considering both a differential diagnosis and reminding readers of current knowledge around the subject matter.

  • Experimental Endocrinology

    A Sourcebook of Basic Techniques
    • 1st Edition
    • M Zarrow
    • English
    Experimental Endocrinology: A Sourcebook of Basic Techniques focuses on techniques and methodologies used in conducting experiments on endocrinology. The manual discusses the sources, nature, action, and assays of hormones and estrogens. Biosynthesis, metabolism, and mechanisms of action of hormones; sites of estrogen formation; and biogenesis, metabolism, and mechanism of action are discussed. The book also focuses on the nature, action, and assays of progestogens, relaxin, androgens, epinephrine and norepinephrine, adrenal corticoids, and thyroid hormones. Experiments are presented to show the varying effects of these hormones on animals. The manual also focuses on somatotropin, corticotropin, and thyrotropin. Sites of formation; nature of the hormones; action of STH, ACTH, and TSH; and biogenesis, metabolism, and mechanism of action are discussed. The book also discusses gonadotropins, oxytocin, vasopressin, and melanocyte stimulating hormone; parathormone; insulin and glucagon; and invertebrate hormones. The manual is a reliable source of information for students and readers interested in studying endocrinology.

  • Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases

    • 1st Edition
    • Volume 4
    • Michael Lockshin + 1 more
    • English
    This volume of the Handbook of Systemic Autoimmune Diseases series represents a medical collaboration focusing primarily on female aspects of rheumatic diseases. This collaboration recognizes the need to understand and optimally manage the care of women with autoimmune conditions that may affect their reproduction and hormonal status. This handbook will prove useful to clinicians and researchers alike. It covers practical points, ranging from which anti-rheumatic medications are safe in pregnancy to how to counsel women with scleroderma contemplating pregnancy.

  • Growth Hormone Secretagogues

    Basic Findings and Clinical Implications
    • 1st Edition
    • E. Ghigo + 3 more
    • English
    Growth hormone secretagogues (GHS) administered alone or in combination with growth hormone releasing hexapeptides, are effective probes for the diagnosis of GH deficiency in both children and adults. Current research has developed and tested different GHS compounds that are active by the oral route, and have improved potency and bioavailability, giving rise to exciting therapeutic possibilities.There was an enthusiastic response from experts in this area to the idea of distilling the huge amount of available data into one multi-authored volume. Each contributor has advanced the field of knowledge, and has here emphasized the practical aspects of their work, reviewing the subject in the light of their own experience. Therefore, the theme of the book is a practical one.The volume deals with all aspects of GHS that are relevant to the field, from the chemical structure to the different analogues, to the cloning and expression of the GHS-receptor and the role of these compounds in the physiological control of GH secretion. Also discussed are the most recent advances in relation to the possible role of these compounds in the diagnostic therapeutic settings in different clinical situations, either in children, adults or the elderly.The book meets the requirement of covering most, if not all of the advances in the field. It will enable scientists and clinicians to keep abreast of the rapidly evolving knowledge of the most recent years, and will also prove useful as a review for all interested in this topic.