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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

    • Dictionary of Immunology 4E

      • 4th Edition
      • June 7, 1995
      • W. John Herbert + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 7 5 2 0 2 5 4
      This is the fourth edition of a well-established dictionary of Immunology which has been completely revised and updatedto include key terms arising from new discoveries in the fast-developing fields of molecular and cellular immunology. It also contains brief descriptions of the most commonly used immunological techniques, as well as definitions, useful in clinical immunology, of immunodeficiency states, autoimmune diseases etc. Clear illustrations and tables have been added to illustrate the text where appropriate. The book should be readily understandable by anyone with a background in biology and many of the definitions should be understandable to the general reader, especially as terms are extensively cross-referenced.It should be useful to those attending immunological meeting or reading immunological journals, especially as scientists communicating to specialized audiences rarely define their terms.It will also be invaluable to undergraduate and postgraduate students in biological and medical sciences, since immunological methods, such as use of monoclonal antibodies, are in wide use throughout biology and medicine.
    • Immunopharmacology of Free Radical Species

      • 1st Edition
      • May 15, 1995
      • English
      • Paperback
        9 7 8 0 1 2 3 8 8 4 5 3 4
      • eBook
        9 7 8 0 0 8 0 5 3 4 5 4 1
      Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.
    • Mechanisms and Models in Rheumatoid Arthritis

      • 1st Edition
      • March 16, 1995
      • B. Henderson + 2 more
      • English
      • eBook
        9 7 8 0 0 8 0 5 3 6 0 2 6
      Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models in great detail from their development through to reviews of the most recent information on each model.Mechanisms and Models in Rheumatoid Arthritis brings together a group of eminent researchers from the fields of clinical rheumatology, pathology, experimental pathology, immunology, connective tissue biochemistry, microbiology, pharmacology and developmental biology to describe the current views of the cellular and humoral mechanisms that drive the pathology of rheumatoid arthritis and experimental models of rheumatoid arthritis.
    • Advances in Immunology

      • 1st Edition
      • Volume 58
      • February 13, 1995
      • English
      • Paperback
        9 7 8 0 1 2 3 9 9 3 9 8 4
      • Hardback
        9 7 8 0 1 2 0 2 2 4 5 8 6
      • eBook
        9 7 8 0 0 8 0 5 7 8 3 4 7
      This text should be a useful guide for researchers in immunology, cell and molecular biology and development biology.
    • Advances in Cancer Research

      • 1st Edition
      • Volume 65
      • December 23, 1994
      • English
      • Paperback
        9 7 8 0 1 2 4 1 5 7 0 5 7
      • eBook
        9 7 8 0 0 8 0 5 6 2 4 7 6
      Foundations in Cancer Research has been a feature of Advances in Cancer Research since Volume 59 in 1992. Foundations chapters provide reviews of historical and scientific depth in order to explain studies, events, and personalisties that have had a major impact upon the development of cancer research. Key ideas in these studies still inform current research thinking.In Volume 65, the Editors present a marvelous group of seven new Foundations chapters within a single volume. Subsequent volumes will return to the orginal format of one or two Founations chapters in each volume of the Serial.
    • Autoimmune Disease Models

      • 1st Edition
      • November 9, 1994
      • Irun R. Cohen + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 5 4 7 1 8
      • Hardback
        9 7 8 0 1 2 1 7 8 3 3 0 3
      • eBook
        9 7 8 0 0 8 0 9 1 7 3 6 8
      Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.
    • Adhesion Molecules

      • 1st Edition
      • October 25, 1994
      • English
      • Hardback
        9 7 8 0 1 2 7 4 1 4 4 0 9
      • eBook
        9 7 8 0 0 8 0 9 2 6 4 8 3
      The consequences of diseases involving the immune system such as AIDS, and chronic inflammatory diseases such as bronchial-asthma, rheumatoid arthritis and atherosclerosis, now account for a considerable economic burden to governments worldwide. In response there has been an enormous research effort investigating the basic mechanisms underlying such diseases, and a tremendous drive to identify novel therapeutic applications for their prevention and treatment. Though a plethora of immunological studies have been published in recent years, little has been written about the implications of such research for drugs development. As a consequence, this area has not gained the prominence of other fields such as molecular pharmacology or neuropharmacology, and a focul information source for the many pharmacologists interested in diseases of the immune system remains unpublished.The Handbook of Immunopharmacology series provides such a source through the commissioning of a comprehensive collection of volumes on all aspects of immunopharmacology. Editors have been sought after for each volume who are not only active in their respective areas of expertise, but who also have a distinctly pharmacological bias to their research.The series follows three main themes, each represented by volumes on individual component topics. The first covers each of the major cell types and classes of inflammatory mediators ("cells and mediators"). The second covers each of the major organ systems and the diseases involving the immune and inflammatory responses that can effect them ("systems"). The third covers different classes of drugs currently used to treat these diseases as well as those under development ("drugs").This volume provides a comprehensive overview of the adhsion molecules, processes and concepts that govern both inflammatory and infectious diseases, and also deals in detail with the specific in vivo pathways involved.The first chapter introduces some of the molecules that mediate leukocyte adhesion and ranges from their discovery using monoclonal antibodies and a congenital adhesion deficiency, to their antagonism in preliminary clinical trials as novel therapeutics. An in-depth analysis of the structure, distribution and function of the cell surface glycoproteins that regulates lymphocyte (specific immune response), granulocyte (acute inflammatory response) and metastatic cell (malignant processes) adhesions respectively is provided by the next three chapters. Chapters 5 and 7 detail the molecular structure, intracellular pathways, specificty of carbohydrate interactions, and signalling of the molecules that regulate leukocyte-leukocyte and leukocyte-mesenchyma... cell interactions.There follows an exploration into the contributions of specific molecules in inflammatory diseases in various organs from chapters 8-11. The concluding part is unique to this volume by reviewing the comparable, and in some cases same, cell surface molecules that mediate virus, bacteria and parasite interactions with host cells.The research is far from complete, but Adhesion Molecules is extremely comprehensive and will be a valuable resource for many a year to come.
    • Immunopharmacology of Epithelial Barriers

      • 1st Edition
      • February 21, 1994
      • English
      • Hardback
        9 7 8 0 1 2 2 8 8 0 3 0 8
      • eBook
        9 7 8 0 0 8 0 9 1 8 4 0 2
      The realisation that epithelial tissues are not simply passive barriers to the adsorption of materials into internal environments has brought about an enormous growth of investigation of mucosal functions and their active and passive protective roles. Epithelia are highly organized but complex structures, subserving numerous functions, including immunological defence. The use of pharmacological tools in these systems is increasing, which is improving our understanding of epithelial immunobiology. This volume adopts a step-by-step approach, whereby each chapter builds upon the previous one, progressively adding important foundation information, culminating in a series of chapters concerning particular epithelia, including respiratory, gastrointestinal, renal and ocular. The result is a comprehensive but integrated treatise of epithelial function and its immunopharmacology, which aims to serve as an appropriate starting point at which the clinical pulmonologist and the research scientist can obtain an appreciation of some aspects of epithelial immunopharmacology as they are currently understood.
    • Advances in Immunology

      • 1st Edition
      • Volume 55
      • January 28, 1994
      • English
      • eBook
        9 7 8 0 0 8 0 5 7 8 3 1 6
      Approx.455 pages
    • Advances in Cancer Research

      • 1st Edition
      • Volume 62
      • January 21, 1994
      • English
      • Paperback
        9 7 8 0 1 2 4 0 1 4 1 8 3
      • eBook
        9 7 8 0 0 8 0 5 6 2 4 4 5
      This latest volume of the biannual serial continues rapid, current coverage of all aspects of the molecular basis of human cancer, functions of oncogenes, and research strategies for cancer drug development and treatment. Topics reviewed in Volume 62 include chromosomes and cancer; pathways in Ras function; APC gene in human cancer; molecular cytogenetics of renal cell tumors; reverse transformation, genome exposure, and cancer; peptide-binding heat shock proteins in endoplasmic reticulum; new developments in the Epstein-Barr virus field; direct cellular communication and humoral immune response.