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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

    • Immunological Tolerance

      • 1st Edition
      • June 28, 2014
      • David H. Katz + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 1 4 1 8
      • eBook
        9 7 8 1 4 8 3 2 7 3 4 3 3
      Immunological Tolerance: Mechanisms and Potential Therapeutic Applications documents the proceedings of a conference held at Brook Lodge, Michigan, April 27-May 1, 1974. The conference brought together many of the investigators who have actively contributed to furthering knowledge and understanding of immunological tolerance. It will be immediately clear to the reader that the conference was structured in a way to consider phenomena of tolerance and immune suppression as interrelated entities with a certain degree of emphasis on the possible common cellular mechanisms involved. The volume contains 36 contributions presented during the seven sessions of the conference. The papers presented in Session I examined T-cell tolerance. The presentations in Session II focused on B cell tolerance. The papers in Sessions III and IV focused on the mechanisms of B cell and T cell tolerance, respectively. Session V dealt with the activity of suppressor cells as a mechanism of tolerance. The papers in Session VI investigated the suppressive activity of antibody and antigen-antibody complexes. In Session VII a final General Discussion was held in order to identify what has been established concerning the phenomenology and mechanisms of specific immunological tolerance, what are the major unresolved issues, and what approaches appear most promising to answer these questions.
    • Methods in Virology

      • 1st Edition
      • June 28, 2014
      • Karl Maramorosch + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 1 9 1
      • eBook
        9 7 8 1 4 8 3 2 5 9 0 1 7
      Methods in Virology, Volume VIII focuses on the methods used in virology, including microscopy, hybridization, viruses, and fingerprint analysis. The selection first offers information on the hybridization of viral nucleic acids; applications of oligonucleotide fingerprinting to the identification of viruses; and immunosorbent electron microscopy in plant virus studies. Discussions focus on the detection of double-stranded RNA, principles and mechanisms of fingerprint analysis, preparation of labeled nucleic acid probes, and basic methods of nucleic acid hybridization. The text then elaborates on quantitative transmission electron microscopy for the determination of mass-molecular weight of viruses and use of thin sectioning for visualization and identification of plant viruses. Topics include technical procedures for processing plant tissues, cytological modifications of diagnostic value, procedure and treatment of data to obtain the average mass of virus particles, and applications in virology. The book takes a look at the detection of genome-linked proteins of plant and animal viruses; methods for assay, purification, and characterization of prions; and the use of mosquitoes to detect and propagate viruses. The selection is a valuable source of information for researchers interested in the methods employed in virology.
    • Methods in Virology

      • 1st Edition
      • June 28, 2014
      • Karl Maramorosch + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 6 2 2 6 0
      Methods in Virology, Volume III focuses on the advancements of methods employed in virology, including immunological, microscopic, and serological techniques and transformation assays. The selection first offers information on the analysis of protein constituents and lipid components of viruses. Discussions focus on the applications of the existing methodology to lipid-containing viruses; physical methods for the characterization of virus proteins; renaturation of virus proteins and reconstitution of viruses; and chemical methods for the characterization of virus proteins. The text then elaborates on RNA polymerase, immunological techniques for animal viruses, and serological techniques for plant viruses. The book tackles the plaque assay of animal viruses, transformation assays, and the methods for selecting RNA bacteriophage. Topics include identification of the nucleic acid, assay methods for particular viruses, general consideration of the plaque assay method, virus-dilution media and procedures, monolayer assay methods, and incubation and staining of plates and counting of plaques. The manuscript also takes a look at the structural studies of viruses, microscopic techniques, electron microscopy of isolated virus particles and their components, and the application of thin sectioning. The selection is a vital source of data for researchers interested in the methods employed in virology.
    • Membranes and Viruses in Immunopathology

      • 1st Edition
      • June 28, 2014
      • Stacey B. Day + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 6 7 4 9 4
      Membranes and Viruses in Immunopathology covers the proceedings of the 1972 symposium by the same title, held at the University of Minnesota Medical School, sponsored by the Bell Museum of Pathology. This book is composed of 40 chapters that highlight the significant advances in fundamental experiments of membrane structure chemistry. Considerable chapters explore the diagnosis and analysis of slow and oncogenic virus infections, as well as the role of immunobiologic processes in the pathogenesis, prevention, and treatment of disease. The remaining chapters contain research works on the detailed mechanisms that may contribute to cancer induction and dissemination. This book will prove useful to immunopathologists and practicing physicians.
    • Immunobiology of the Complement System

      • 1st Edition
      • June 28, 2014
      • Gordon D. Ross
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 5 7 1 3
      • eBook
        9 7 8 1 4 8 3 2 7 6 3 9 7
      Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine provides an introduction to the complement system. The intention was to create a primer that would provide the basic knowledge of complement required for either research or clinical medicine in diseases involving the complement system. The book begins with a historical background of complement research; it introduces certain key investigators from the past who have made important contributions. Separate chapters on the basic aspects of complement function are followed by chapters on the molecular genetics of complement and the role of complement in different diseases. Key topics discussed include the activation of complement via the classical pathway and the alternative pathway; complement mediators of inflammation; opsonization and membrane complement receptors; assembly and functions of the terminal components; and complement-dependent mechanisms of virus neutralization. This book has been written primarily for students and scientists who have not been specifically trained in complement research.
    • Centrifugation in Density Gradients

      • 1st Edition
      • June 28, 2014
      • C. A. Price
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 4 9 7 6
      • eBook
        9 7 8 1 4 8 3 2 8 2 0 6 0
      Centrifugation in Density Gradients provides information pertinent to the fundamental aspects of density gradient centrifugation. This book discusses the benefits of density gradient centrifugation to membrane-bound particles. Organized into nine chapters, this book begins with an overview of the method of differential or fractional centrifugation. This text then explores the physical basis of density gradient centrifugation. Other chapters deal with the nuts and bolts of density gradient centrifugation, the construction and composition of gradients, the properties and operation of centrifuge systems, and certain arcane but highly useful procedures. This book discusses as well density gradient centrifugation in the analytical ultracentrifuge. The final chapter deals with a collection of protocols for separating particles ranging in size from whole cells to macromolecules. This book is intended to be suitable for readers who need to separate biological particles. Biologists, chemists, biochemists, cytologists, physiologists, scientists, and research workers will also find this book useful.
    • Immunobiology of the Macrophage

      • 1st Edition
      • June 28, 2014
      • David S. Nelson
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 4 0 1 3
      • eBook
        9 7 8 1 4 8 3 2 7 4 7 7 5
      Immunobiology of the Macrophage presents an account of the state of knowledge of the immunobiology of the macrophage. The book’s contributors—immunol... of diverse scientific and geographic backgrounds—have been encouraged to give personal accounts of developments in their special fields of interest as well as critical surveys of the backgrounds leading to these developments. The book begins with a study on the functions of macrophages in the initiation and regulation of antibody responses in vitro. This is followed by separate chapters on topics such as the role of macrophages in making antigen more immunogenic and less tolerogenic; functional distinctions between macrophages at different sites; and the role of the macrophage in antigen recognition by T lymphocytes. Subsequent chapters examine interactions between macrophages and lymphocytes in the production of interferon and other mediators of cellular immunity; macrophage cell lines and their uses in immunobiology; and cytotoxic macrophages in allograft rejection.
    • Clinical Immunobiology

      • 1st Edition
      • Volume 3
      • June 28, 2014
      • Fritz H. Bach + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 9 1 4
      • eBook
        9 7 8 1 4 8 3 2 1 6 3 4 8
      Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual. This volume is composed of 21 chapters and begins with a presentation of the background and issues to which clinical tests would be applied. The succeeding chapters outline the methodological procedures used in the analyses. Other chapters present some examples of the kinds of data that can be generated with the procedures used and provide guidelines for interpretation of the tests. The remaining chapters discuss the value of the immunological test procedures in differential diagnosis and analysis of diseases. These chapters also explore the usefulness of these procedures in prognosis of disease and the consequences of immunological manipulation undertaken for treatment or prevention of disease. This book will be of great value to clinical immunobiologists, biochemists, and researchers.
    • Blood and Tissue Antigens

      • 1st Edition
      • June 28, 2014
      • David Aminoff
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 5 5 1 6
      • eBook
        9 7 8 1 4 8 3 2 8 2 4 3 5
      Blood and Tissue Antigens documents the proceedings of the International Symposium on Blood and Tissue Antigens held in Ann Arbor, Michigan on September 17-19, 1969. This book focuses on the immunogenetic and biochemical aspects of the blood and tissue antigens. The topics discussed include the genetics of blood groups; blood groups and serum phosphatase; immunogenetics of the mouse H-2 system; and glycolipids as membrane antigens. The carbohydrate composition of epithelial mucins; glycolipids in SV40 and polyoma virus transformed mouse cell lines; and metabolic variations of serum proteins and enzymes are also elaborated. This text likewise covers the action of glycosidases on erythrocytes; blood group specific oligosaccharides in urine; biosynthesis of submaxillary mucins; and genes, glycosyltransferases... and blood types. This publication is a good source for students and individuals researching on blood and tissue antigens.
    • Fish Immunology

      • 1st Edition
      • June 28, 2014
      • Margaret J. Manning + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 1 5 3
      • eBook
        9 7 8 1 4 8 3 2 7 0 3 2 6
      Fish Immunology contains the proceedings of a symposium organized by the Fisheries Society of the British Isles, held in Plymouth, England, 11-13 July 1983. This volume contains 29 chapters and opens with a study on the prevention of disease outbreak or treatment of disease in fish farms with drugs or chemicals. Separate chapters follow on topics such as immune phenomena in Teleostei or Anura; phagocytosis in fish; the granulocytes of three elasmobranch species, namely Scyliorhinus canicula, Raja clavata and R. microcellata; and phagocytic cells in the dogfish (Scyliorhinus canicula l.); and levels of α-precipitin in two groups of wild fish: a group believed to be suffering from Ulcerative Dermal Necrosis (UDN) and a healthy group showing no external evidence of disease. Subsequent chapters deal with sequential antigenic competition in teleosts challenged with the fish-furunculosis bacterium Aeromonas salmonicida; the occurrence of vaccine uptake at the skin surface of rainbow trout; and vaccination and development of immunological memory in carp.