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Elsevier

Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

  • Basic Immunology

    Functions and Disorders of the Immune System
    • 7th Edition
    • Abul K. Abbas + 2 more
    • English
    **Selected for 2026 Doody's Core Titles in Immunology**Meticulo... reviewed and updated for today's medical students, Basic Immunology, 7th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume has been fully revised to include recent important advances in our understanding and knowledge of the immune system. A student favorite through six outstanding editions, this new edition uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help you master this complex topic in the most efficient, effective manner possible.

  • Advances in Immunology

    • 1st Edition
    • Volume 157
    • Frederick W. Alt + 1 more
    • English
    Advances in Immunology, Volume 157, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Antigen receptor structure and signaling, T cells in the brain inflammation, The molecular mechanism of RIG-I/MDA5 activation and signaling, GSDMD biology, cGAS-STING pathway, The CARD8 inflammasome in HIV infection, and much more.

  • In Silico Approach Towards Magnetic Fluid Hyperthermia of Cancer Treatment

    Modeling and Simulation
    • 1st Edition
    • Muhammad Suleman
    • English
    In Silico Approach Towards Magnetic Fluid Hyperthermia in Cancer Treatment: Modeling and Simulation presents mathematical modeling and simulation approaches contrary to costly and time consuming in-vivo and in-vitro studies. Finite element method-based models of all hyperthermia processes of liver, brain and breast tumors are simulated on COMSOL Multiphysics software. Problems of constant versus variable heat sources, the backflow problem, the enhanced permeation and retention effect, the flow around Happel’s sphere in cells model structure, the deformation effect in poroelastic brain tumor, 3D flow through porous tissue, the reacting nanofluid flows, and optimization of parameters have been simulated for quantitative analysis. This important reference aids in hyperthermia treatment planning in clinical applications and provides an important compendium for practitioners as well as non-medical practicing scientists and engineers and is resource for both research and medical practice in hyperthermia treatment planning in clinical applications.

  • Translational Autoimmunity, Volume 6

    Advances in Autoimmune Rheumatic Diseases
    • 1st Edition
    • Nima Rezaei
    • English
    Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren’s syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell-based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource.

  • Novel Methods and Pathways in Cancer Glycobiology Research

    • 1st Edition
    • Volume 157
    • English
    Cancer glycobiology is a blazing hot area of cancer research with aberrant post-translational glycosylations on lipids and proteins considered critical for cancer development and metastasis. The NIH/NCI Alliance of Glycobiologists for Cancer Research is a consortium of (10) tumor glycobiology laboratories funded to investigate how cancer-associated glycans (CAG) impact the development and metastasis of cancer. The hope of this momentous effort is to discover CAGs for use as novel biomarkers to detect early-stage cancer or its aggressive behavior or, alternatively, as novel molecular targets with the promise of a curative approach to cancer therapy. The mission of the ‘Alliance’ is to study structure and function of CAGs in cancer development and to provide clinically useful biomarkers for detecting cancer early or the potential of metastasis. This charge has stimulated extensive collaborations across US and International institutions to accelerate discovery of glycan-based biomarkers to the forefront of NCI's efforts to diagnose early-stage cancer and provide curative anti-cancer therapies. The main goals of these research efforts are: 1. To identify and study how cancer-associated glycans functionally impact cancer growth and metastasis2. To identify cancer-associated glycans that can serve as biomarkers for the detection or progression of cancer3. To develop cancer-associated glycans as novel therapeutic targets for the treatment and cure of cancer This volume consists of (9) chapters, one from each funded laboratory, that reviews new methods and mechanisms highlighting glycoconjugates and their roles as cancer biomarkers and/or anti-cancer therapeutic targets.

  • Allergic and Immunologic Diseases

    A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases
    • 1st Edition
    • Christopher Chang
    • English
    Allergic and Immunologic Diseases: A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases is a valuable resource for researchers in and others in the actual day to day practice of allergy and immunology, with specific information, protocols and algorithms to guide their thinking. It is not meant to be a cookbook, yet it provides practical and usable information and an explanation of why and how we do things the way we do. It also addresses limitations of testing and treatment, and how what we know and what we do not know impacts our choices. It also focuses on scientific based practices, and the known pathophysiology of allergic and immunologic diseases as well as mechanisms of action of various treatment modalities. This book is unique in that it explains the rationale behind everything we do in allergy and immunology and it offers the reader specific information on how to do procedures, order tests and treat allergic and immunologic diseases.

  • Advances in Immunology

    • 1st Edition
    • Volume 155
    • English
    Advances in Immunology, Volume 155, the latest release in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Sections of note cover B cell/GC material.

  • Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

    • 1st Edition
    • Moulay Mustapha Ennaji
    • English
    Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms.

  • Translational Autoimmunity, Volume 5

    Challenges for Autoimmune Diseases
    • 1st Edition
    • Nima Rezaei
    • English
    Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing.

  • System Vaccinology

    The History, the Translational Challenges and the Future
    • 1st Edition
    • Vijay Kumar Prajapati
    • English
    Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

  • The Paradox of the Immune System

    Protection, Chronic Inflammation, Autoimmune Disease, Cancer, and Pandemics
    • 1st Edition
    • Louis J. Catania
    • English
    The Paradox of the Immune System: Protection, Inflammation, Autoimmune Disease and Beyond provides a provocative approach to immunology as a "double-edged sword." While it is our greatest protector, it is also the cause of chronic inflammation that leads to autoimmune disease, cancer and infectious diseases like COVID-19. Sections cover the basic science of immunology and its intimate genetic associations, biomedical hypotheses asserting immunology as the basis of all human diseases, and elaborate on immunology as "the enemy within us." This engaging, original approach to a science so personal provides new and invaluable understanding on the bioscience that controls our lives.

  • Immunology of Recurrent Pregnancy Loss and Implantation Failure

    • 1st Edition
    • Joanna Kwak-Kim
    • English
    Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches.

  • Nanotheranostics for Treatment and Diagnosis of Infectious Diseases

    • 1st Edition
    • Keerti Jain + 1 more
    • English
    Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials. Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases.

  • Translational Autoimmunity, Volume 4

    Autoimmune Diseases in Different Organs
    • 1st Edition
    • Nima Rezaei
    • English
    As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases, autoimmune neurologic diseases such as multiple sclerosis, as well as autoimmune hepatobiliary diseases, autoimmune renal diseases and autoimmune cutaneous diseases as the subject of discussion in Translational Autoimmunity: Autoimmune Diseases in Different Organs.

  • Stromal Signaling in Cancer

    • 1st Edition
    • Volume 154
    • English
    Stromal Signaling in Cancer, Volume 154 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics surrounding cancer research. Each chapter is written by an international board of authors.

  • Translational Autoimmunity, Volume 3

    Autoimmune Disease Associated with Different Clinical Features
    • 1st Edition
    • Nima Rezaei
    • English
    Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases).

  • Immunogenetics: A Molecular and Clinical Overview

    Clinical Applications of Immunogenetics
    • 1st Edition
    • Muneeb U Rehman + 3 more
    • English
    Clinical Applications of Immunogenetics: Immunogenetics: A Molecular and Clinical Overview, Volume II provides readers with an exclusive, updated overview of scientific knowledge, achievements and findings in the field of immunogenetics. In thirteen chapters, the book gives insights in new advancements and approaches in viral and autoimmune diseases. Specific chapters are dedicated to immunogenetic mechanisms in the treatment of immune disorders, cancer, neurological and neurodegenerative disorders. In addition, other chapters cover immunogenomics in precision medicine, clinical medicine and transplantation. Finally, a special chapter, COVID-19: A novel challenge to human immune-genetic machinery, updates on thoughts surrounding the pandemic.

  • Vaccinology and Methods in Vaccine Research

    • 1st Edition
    • Rebecca Ashfield + 3 more
    • English
    Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field. It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodologi... advice.

  • The Lung in Autoimmune Diseases

    • 1st Edition
    • Volume 17
    • Fabiola Atzeni + 2 more
    • English
    The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, prognosis and risks to treatment, this book provides a comprehensive approach for the role of the lung in autoimmune diseases and the influence of autoimmune disease on the lung’s functionality. In recent years, there is increasing knowledge in the field, including lung infection in early disease stages, mechanisms involved in lung damage, and new treatments. Recognition of lung involvement and implementation of some specific therapies is an important issue for clinicians dealing with systemic autoimmune diseases.

  • Cardiovascular Pathology

    • 5th Edition
    • L. Maximilian Buja + 1 more
    • English
    Cardiovascular Pathology, Fifth Edition provides a comprehensive treatise on the pathology of cardiovascular diseases, combining presentations of detailed pathology of cardiovascular diseases coupled with contemporary insights into etiology and pathogenesis. Twenty-two chapters cover general topics, including cardiovascular genetics, heart failure, and transplantation, and specific congenital and acquired cardiovascular diseases, therapeutic interventions, and forensic aspects. New chapters address the scope of practice and training in cardiovascular pathology, with a focus on major diagnostic approaches used in contemporary practice and research in cardiovascular pathology, and a perspective on the field of cardiovascular regenerative medicine linked to the basic pathobiology of cell-based therapy. The book provides a unique combination of details of pathological anatomy essential for pathologists involved in the evaluation of cardiovascular specimens and cardiovascular diseases, and is an excellent reference for anyone interested in the natural history and therapeutic advances in the cardiovascular field.

  • A New History of Vaccines for Infectious Diseases

    Immunization - Chance and Necessity
    • 1st Edition
    • Anthony R. Rees
    • English
    A New History of Vaccines for Infectious Diseases: Immunization - Chance and Necessity covers the developments of vaccines and how they have obliterated many fatal diseases and infections over time. The book treads a neutral path but does not avoid discussion. As uncertainty in the outcome of vaccination can only be determined by experiment, the path to vaccine development has been scientifically complex because the immune system and the manner in which humans respond to infection is variable and complex. Finally, the book describes the risks and benefits of vaccines in a visibly objective manner.

  • Avian Immunology

    • 3rd Edition
    • Bernd Kaspers + 3 more
    • English
    Avian Immunology, Third Edition contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers, include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. With contributions from the foremost international experts in the field, Avian Immunology 3rd, provides the most up-to-date crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. Avian Immunology, Third Edition, is a fascinating and growing field and surely provides new and exciting insights for mainstream immunology in the future.

  • Advances in Immunology

    • 1st Edition
    • Volume 152
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 152, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, including chapters that cover Renal diseases and the role of complement in their pathogenesis, Factor H and Properdin and their regulation, Complement in neuronal diseases, Complement and the brain.

  • Advances in Immunology

    • 1st Edition
    • Volume 151
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 151, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Cancer Immunology and Immunotherapy

    Volume 1 of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy
    • 1st Edition
    • Mansoor M. Amiji + 1 more
    • English
    Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.

  • Lahita's Systemic Lupus Erythematosus

    • 6th Edition
    • Robert Lahita
    • English
    Lahita's Systemic Lupus Erythematosus, Seventh Edition is a current, authoritative reference on systemic lupus erythematosus (SLE), one of the most heterogeneous and mechanistically complex of autoimmune diseases. The field has undergone rapid transformation since the previous edition, with regulatory approval of targeted biologics, clarification of molecular mechanisms driving immune dysregulation, and the emergence of precision medicine approaches to patient stratification. This volume addresses the demand for a comprehensive, integrated resource reflecting these advances for specialists in SLE research and clinical care.The reference spans the full breadth of SLE biology and clinical management. Content covers the genetic and epigenetic determinants of susceptibility, B and T cell dysregulation, innate immune mechanisms including interferon signaling and neutrophil biology, complement activation, microbiome contributions, and metabolic dysfunction in immune cells. Clinical content addresses the presentation and management of SLE across organ systems—including renal, neuropsychiatric, cardiovascular, pulmonary, cutaneous, musculoskeletal, and hematologic manifestations—along... antiphospholipid syndrome and malignancy surveillance. Therapeutic chapters span antimalarials and glucocorticoids through approved targeted biologics and investigational CAR-T cell approaches, with attention to pregnancy management, global health disparities, and precision treatment strategies.Lahita's Systemic Lupus Erythematosus equips rheumatologists, clinical immunologists, and multidisciplinary specialists with the scientific foundation and clinical guidance required for contemporary SLE practice. Contributions from international experts spanning five continents provide a global perspective on disease heterogeneity and outcomes. Integrated coverage of AI-assisted monitoring, molecular biomarkers, and precision stratification frameworks positions this reference as essential reading for clinicians and translational researchers in autoimmunity.

  • Advances in Immunology

    • 1st Edition
    • Volume 150
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 150, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Inmunología

    • 9th Edition
    • David Male + 2 more
    • Spanish
    Novena edición que ofrece una aproximación bien ilustrada y cuidadosamente estructurada que incluye todos los conceptos básicos y clínicos necesarios para la preparación de los cursos de la especialidad. La obra ha sido editada y redactada por expertos docentes e investigadores, por lo que proporciona un contenido coherente y de vanguardia que vincula el laboratorio y la práctica clínica. Presenta un contenido reorganizado que muestra la inmunología en el orden en que se suele enseñar y aprender, integrando mejor la inmunología básica y la clínica. Aborda nuevos temas, como las células linfocíticas innatas, los tratamientos basados en anticuerpos y la ingeniería de anticuerpos, la inmunidad innata y sus componentes, la genética de las enfermedades con base inmunitaria, la medicina personalizada y los fármacos inmunoterapéuticos para el tratamiento del cáncer. Con un formato fácil de usar y codificado con colores, incluye cuadros con conceptos clave, diagramas explicativos y casi 200 fotografías para ayudar a comprender y memorizar de forma visual los conceptos más difíciles. Además ofrece resúmenes de capítulo, cuadros de razonamiento crítico y preguntas basadas en casos clínicos que facilitan una revisión rápida y eficaz para la preparación de los exámenes. Explica los componentes básicos del sistema inmunitario (células, órganos y moléculas receptoras principales), así como la activación y las acciones de la respuesta inmunitaria, especialmente en el contexto clínico y proporciona la información clínica más actualizada, incluidos los más recientes abordajes clínicos de la inmunología del cáncer, el trasplante, la autoinmunidad y la hipersensibilidad, entre otros. Incluye el acceso a la versión electrónica del libro en Student Consult, que cuenta con textos ampliados, figuras y tablas adicionales, un banco de preguntas de autoevalución complementario y un total de 16 vídeos. El contenido incluido en Student Consult está íntegramente en inglés.

  • Cellular and Molecular Immunology

    • 10th Edition
    • Abul K. Abbas + 2 more
    • English
    Well-written, readable, and superbly illustrated, Cellular and Molecular Immunology, 10th Edition, continues the tradition of excellence established through multiple editions of this bestselling text. Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging information in this challenging area. It’s an ideal resource for medical, graduate, and undergraduate students, as well as a trusted reference for physicians and scientists.

  • Mechanisms and Therapy of Liver Cancer

    • 1st Edition
    • Volume 149
    • English
    Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver Cancer, Immunotherapy of Liver Cancer, and Desmoplastic Tumor Microenvironment and Intrahepatic Cholangiocarcinoma Progression: Mechanisms and Therapeutic Implications.

  • Advances in Immunology

    • 1st Edition
    • Volume 148
    • English
    Advances in Immunology, Volume 148 offers the latest release in a long-established and highly respected publication, presenting current developments and comprehensive reviews in immunology. Sections in this new volume include chapters on histone deacetylases as targets in autoimmune and autoinflammatory diseases, the role of NK cell as central communicators in cancer immunity, and the mechanism and regulation of class switch recombination by transcriptional control element.

  • Stiehm's Immune Deficiencies

    Inborn Errors of Immunity
    • 2nd Edition
    • Kathleen E. Sullivan + 1 more
    • English
    Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy.

  • Advances in Immunology

    • 1st Edition
    • Volume 146
    • English
    Advances in Immunology, Volume 146, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies, T cells in latent viral infections, Preserving Immune Homeostasis with A20, Transcriptional control in the context of innate and adaptive lymphoid development, RAG and AID structural biology and the important insights it has generated for the V(D)J recombination and CSR/SHM fields, and more.

  • Systemic Lupus Erythematosus

    Basic, Applied and Clinical Aspects
    • 2nd Edition
    • George C. Tsokos
    • English
    This completely updated and expanded 2nd edition of Systemic Lupus Erythematosus, A Manual includes topics not covered previously with contributors who are at the forefront of each specific topic and with a global appeal. Each chapter is short and is presented critically with selected references, which should be valuable to a wider audience. This book combines basic with clinical science to help internists and specialists in the diagnosis and management of patients with SLE. It is a quick referral for people in the pharmaceutical industry in their efforts to bring much-needed drugs. It provides all the needed information to basic researchers old and new alike, who wish to enter the field of lupus and systemic autoimmunity in general.

  • Infections in Systemic Autoimmune Diseases

    Risk Factors and Management
    • 1st Edition
    • Volume 16
    • English
    Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who’s who of clinical researchers in the field.

  • Innate Immunity

    From Louis Pasteur to Jules Hoffmann
    • 1st Edition
    • Yves Carton
    • English
    Innate immunity is a new branch of immunology, confirmed by three Nobel Prize winners in 2011. It is the first line of defense against pathogens and is in a way the preliminary step of adaptive immunity which occurs later, and only present in vertebrates. This book examines the way in which innate immunity was discovered in invertebrates. As a starting point, it looks at the work of Louis Pasteur on silkworm disease and the findings of Ilya Metchnikov, discoverer of phagocytosis. It also investigates André Paillot, who in 1920 demonstrated the existence of humoral immunity in insects, unrelated to the type of immunity that was initially thought to be present in all vertebrates. Finally, Innate Immunity shows how the group directed by Jules Hoffmann found strong similarities between the innate immunity response of insects and mammals. The discovery of a receptor protein in Drosophila, which is also found in humans, was what led to Jules Hoffmann being awarded the Nobel Prize in 2011.

  • The Autoimmune Diseases

    • 6th Edition
    • M. Eric Gershwin + 1 more
    • English
    The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.

  • Farmacovigilancia. Un enfoque práctico

    • 1st Edition
    • Thao Doan + 4 more
    • Spanish
    Obra que se centra en la evolución del panorama normativo, los estudios de casos y el uso actual y futuro de las tecnologías digitales. Este título ofrece información exhaustiva, fácil de leer y actualizada sobre los principios y la práctica de la farmacovigilancia, centrándose en el panorama normativo, en el estudio de casos y en el uso actual y futuro de las tecnologías digitales. Los autores recurren al estudio de casos para asegurar que el contenido es relevante para la práctica diaria. Cubre aspectos como: marco normativo, datos sobre seguridad y de la vida real, temas de interés para poblaciones especiales y el futuro de la farmacovigilancia.

  • Introductory Immunology

    Basic Concepts for Interdisciplinary Applications
    • 2nd Edition
    • Jeffrey K. Actor
    • English
    Introductory Immunology: Basic Concepts for Interdisciplinary Applications, Second Edition is a completely updated, revised and expanded resource on the immune system as a primary defense for the maintenance of health and homeostasis. The book highlights the components of the human immune system and how they work together to confer protection against pathogenic invaders. It also creates an understanding of the basis for clinical tests and immune therapeutics and their importance in identifying and treating disease states. This updated edition will strengthen the foundation required to understand the placement of immune function within clinical practice, thus allowing a basic platform to define therapeutic treatments.

  • Basic Immunology

    Functions and Disorders of the Immune System
    • 6th Edition
    • Abul K. Abbas + 2 more
    • English
    Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help students master this complex topic in the most efficient, effective manner possible.

  • Microbial Diversity in the Genomic Era

    • 1st Edition
    • Surajit Das + 1 more
    • English
    Microbial Diversity in the Genomic Era presents insights on the techniques used for microbial taxonomy and phylogeny, along with their applications and respective pros and cons. Though many advanced techniques for the identification of any unknown bacterium are available in the genomics era, a far fewer number of the total microbial species have been discovered and identified to date. The assessment of microbial taxonomy and biosystematics techniques discovered and practiced in the current genomics era with suitable recommendations is the prime focus of this book.

  • Structural Biology in Immunology

    Structure/Function of Novel Molecules of Immunologic Importance
    • 1st Edition
    • Chaim Putterman + 2 more
    • English
    Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease.

  • The Epigenetics of Autoimmunity

    • 1st Edition
    • Volume 5
    • Rongxin Zhang
    • English
    The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sjögren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 138
    • English
    Advances in Cancer Research, Volume 138, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.

  • Advances in Immunology

    • 1st Edition
    • Volume 137
    • English
    Advances in Immunology, Volume 137, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including sections on Notch and T-Cell signaling/T-Cell memory, Single Cell Analysis of CD8+ and CD4+ T Cell Differentiation, New Developments in the Chemokine Field, the Role of Caveolin-1 in BCR and TCR Receptors, The Unusual Biochemistry of Bovine Immunoglobulins, and the Molecular Aspects of Allergens and Allergy.

  • Inmunología básica para medicina

    • 1st Edition
    • Isabel Olazabal Olarreaga + 1 more
    • Spanish
    Manual conciso que destaca la información más útil para el médico y expone los temas de actualidad para estudiantes y profesionales en los fundamentos de la Inmunología. El contenido más importante de la obra es: 24 temas de inmunología básica con información clínica complementaria; 4 anexos sobre patógenos, trasplantes, oncología y vacunas; cuadros con aspectos de interés generales y médicos, así como resúmenes al final de cada capítulo; guías de seminarios para ayudar a integrar conocimientos; material de carácter molecular esencial; profusamente ilustrado, para ayudar a fijar conceptos inmunológicos. Dirigida a estudiantes de Medicina, médicos de cualquier especialidad y estudiantes de otros grados de ciencias de la salud que necesiten ponerse al día en esta materia de una manera breve, clara y desarrollada de forma que se facilita el autoaprendizaje.

  • Immunology

    Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy
    • 1st Edition
    • M. A. Hayat
    • English
    Immunology, Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy discusses the investment of time, effort and finance that go into making progress in preventing and/or curing serious diseases by using standard treatments (chemotherapy, radiotherapy, surgery, and hormone therapy). The use of these treatments is accompanied by unavoidable, devastating side effects. At the cost of being repetitious, it has to be emphasized that an improved understanding of the immune system, avoidance of unhealthy habits (e.g., smoking, intake of alcohol, perpetual stress, and lack of exercise) and early detection (using biomarkers) are the only three friends we have to at least delay the onset of serious diseases.

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 12
    • 1st Edition
    • M. A. Hayat
    • English
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.

  • miRNA and Cancer

    • 1st Edition
    • Volume 135
    • English
    miRNA and Cancer, Volume 135, the latest volume in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, and includes specific chapters on Non-coding RNAs as Biomarkers of Cancer, The Enigma of microRNA Regulation in Cancer, Animal Models to Study microRNA functions, Non-coding RNAs and Cancer, microRNAs in Cancer Susceptibility, ts-RNAs versus microRNAs, microRNAs and AML, and microRNAs and Epigenetics.

  • Chronic Kidney Disease in Disadvantaged Populations

    • 1st Edition
    • Guillermo Garcia-Garcia + 2 more
    • English
    Chronic Kidney Disease in Disadvantaged Populations investigates the increased incidence and prevalence of kidney disease in vulnerable populations world-wide. The volume explores the complex interactions of genetic, biologic, cultural and socioeconomic factors such as the environment, and specific health behaviors that seem to be responsible for a significant proportion of the health disparities in these communities. Each chapter is written by leading experts in the field and analyzes the prevalence and incidence of pre-dialysis kidney disease in disadvantaged populations across both developed and developing countries. In addition, each contribution analyzes differentiated risk factors and compares the disparities in access to screening, prevention strategies, treatment protocols and renal replacement therapies. Chronic Kidney Disease in Disadvantaged Populations is essential reading for residents, fellows, clinicians and biomedical researchers working in nephrology, internal medicine, and epidemiology, especially those working in areas with high concentrations of disadvantaged populations.

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