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Elsevier

Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

  • Role of Medicinal Plants in Autoimmune Diseases

    Concepts, Perspectives, and Utilization
    • 1st Edition
    • Reetika Mahajan + 4 more
    • English
    Role of Medicinal Plants in Autoimmune Diseases: Concepts, Perspectives, and Utilization provides comprehensive knowledge of autoimmune diseases and the role of various medicinal plant products in their treatment. The book discusses the immune system as a group of complex biological structures and processes in an organism which gives protection against a wide range of pathogenic organisms while simultaneously distinguishing these pathogens from the organism’s own healthy cells and tissues, thus maintaining homeostasis in the body.It has been an age-old practice to use extracts and other parts of various plants in treating many diseases. Several plants contain various pharmacologically active substances which can be used to treat different diseases. Among these medicinal plants, many have shown good immunomodulatory properties and could act as natural immunosuppressant agents in treating autoimmune disorders.

  • Cytokine Response Against Major Human Viral Infections

    • 1st Edition
    • Mukesh Samant + 1 more
    • English
    Cytokine Response Against Major Human Viral Infections provides in-depth coverage of the immunological response against human viral infections and the role and impact of cytokines on disease pathogenesis and host immune response.Cytokines, as a part of innate immunity, initiate the development of antiviral and TH 1-type immune responses. Cytokines also affect the adaptive immune response and disease manifestation. In five sections, this book gives a comprehensive introduction to the clinical manifestations of viral and infectious diseases; details the role of cytokines in DNA virus infections, RNA virus infections, and reverse transcribing virus infections; and gives insights into the recent advances and strategies in diagnostic tools and therapeutic and prophylactic measures.Cytokine Response Against Major Human Viral Infections is valuable resource for both researchers in immunology and virology, as well as for those in the biotech and pharmaceutical industries, engaged in the study of cytokines and their immunological response against human viral infections.

  • A New Era in Alzheimer's Research

    Pathogenesis, Prevention, and Treatment
    • 1st Edition
    • Sandeep Kumar Singh + 1 more
    • English
    A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals.

  • Programa para mejorar la gestión del dolor crónico

    12 sesiones para reaprender a vivir plenamente
    • 1st Edition
    • Carolina BAEZA-VELASCO + 1 more
    • Spanish
    Este libro está pensado para el paciente, concebido como una auténtica guía práctica, es una herramienta de seguimiento y de motivación que le ayudará a centrarse en su objetivo, a no cejar en sus esfuerzos por mitigar el dolor cotidiano y a recuperar la calidad de vida. Las distintas intervenciones psicológicas incluidas no pretenden curar el dolor, sino ayudar a los pacientes a desarrollar recursos psicológicos y a adoptar herramientas eficaces para afrontar mejor el sufrimiento.

  • Cutting Edge Artificial Intelligence, Spatial Transcriptomics and Proteomics Approaches to Analyze Cancer

    • 1st Edition
    • Volume 163
    • English
    Cutting Edge Artificial Intelligence, Spatial Transcriptomics and Proteomics Approaches to Analyze Cancer, Volume 163 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting topics on the Impact of thermal processing on food flavonoids, Bioinformatics and bioactive peptides from foods: does it work together?, Food off-flavor volatiles generation, characterization and advances in novel strategies for mitigating off-flavor perception, Innovations in Food Packaging for a Sustainable and Circular economy, Upcycling of seafood side streams for circularity, Edible insects in foods, Effect of novel food processing technologies on Bacillus cereus spores, and more.

  • Advances in Immunology

    • 1st Edition
    • Volume 163
    • English
    Advances in Immunology, Volume 163, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample chapters include The role of autophagy in RIP1 mediated cell death and intestinal inflammation, IL-17 family cytokines in inflammatory or autoimmune kin diseases, and more.​​​​​​

  • The Immunology of the Cat

    • 1st Edition
    • Ian R. Tizard
    • English
    The Immunology of the Cat makes available the first single-source, comprehensive review of the feline immune system, reporting on all immunologic aspects of diseases of the cat and its relatives and relating recent basic science to important clinical issues. The book opens with the evolution, domestication, and development of the cat then provides detailed information on immunity to infectious diseases, feline allergic diseases, the top feline autoimmune diseases, and feline immunodeficiencies. Content examines feline vaccines, hypersensitivity, cancer, nutrition, and the aged cat. Professionals in veterinary research and practice will appreciate complete information on all aspects of feline immunology in one essential resource.

  • Microbes, Microbial Metabolism and Mucosal Immunity

    An Overview
    • 1st Edition
    • Tanima Bose
    • English
    Microbes, Microbial Metabolism and Mucosal Immunity: An Overview presents a concise and well-vetted treatise on the study of microbiome and microbial metabolites. This volume is up-to-date with the most recent developments from the last decade. It encompasses the interaction of immunity and microbes — and their metabolites — from different mucosal organs including gastrointestinal system, lung, oral cavity, eye. Along with the efficiency of the immune system in inhibiting the growth and proliferation of microbes, the volume discusses how the mediators of the immune system can be targeted to develop therapies.This book presents the latest methods, gives broad and systematic coverage of most mucosal systems and diseases, and takes a fresh perspective that looks at the functional aspects of change in the microbiome. The study of microbiome and microbial metabolites and their roles in host mucosal immunology is a rapidly developing area of research. One major way in which the microbiome influences the host is through altered metabolism. Metabolites, readily available to the host, engender significant consequences. Microbial metabolites have been shown to impact the disease processes in both proximal and distal organs, including the brain in several neurocognitive disorders.

  • Redox Signaling

    • 1st Edition
    • Volume 162
    • English
    Advances in Cancer Research, Volume 162 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • The Rose and Mackay Textbook of Autoimmune Diseases

    • 7th Edition
    • M. Eric Gershwin + 2 more
    • English
    **Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Allergy/Clinical Immunology**The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P’s" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.

  • Current Status of Prostate Cancer: Diagnosis, Biomarkers and Therapies

    • 1st Edition
    • Volume 161
    • English
    Current Status of Prostate Cancer: Diagnosis, Biomarkers and Therapies, Volume 161 in the Advances in Cancer Research series, covers timely topics such as The Prostate Cancer Tissue N-glycome as a Source of Biomarkers, a Progression from Normal to Metastatic Disease, Multiplexed Targeted Proteomics for Prostate Cancer Biomarker Verification, MRI for the Detection of Clinically Significant Prostate Cancer: Update and Future Directions, Genetic and epigenetic factors for prostate cancer progression, Epigenetic regulation of androgen dependent and independent prostate cancer, Molecular Landscape of Prostate Cancer Bone Metastasis, Future of radioligand Therapy in PC, and more.Additional chapters of note include Advancements in Computer Vision and Pathology: Unraveling the Potential of Artificial Intelligence for Precision Diagnosis and Beyond and Extracellular Vesicles in Prostate Cancer.

  • The Immunology of the Dog

    • 1st Edition
    • Ian R. Tizard
    • English
    The Immunology of the Dog is the first readily available, single-source, comprehensive review of the canine immune system. The book discusses all immunologic aspects of diseases of the dog and relates recent basic science to important clinical issues. Sections cover the evolution and domestication of the dog, provide detailed information on immunity to infectious diseases, canine allergic diseases, the top canine autoimmune diseases, and canine immunodeficiencies. This book offers professionals in veterinary research and practice complete information on all aspects of canine immunology in one essential resource.

  • Macrophages Biology and Tissue Inflammation in Health and Disease

    • 1st Edition
    • Stuart Goodman + 2 more
    • English
    Macrophages Biology and Tissue Inflammation in Health and Disease outlines the important role of macrophages—keys cells in the innate immune system—as regulators and orchestrators of inflammation and repair in health and disease. It contains chapters by leading authors on the basic and translational aspects of macrophage biology, covering how to maintained tissue homeostatis and how to deal with internal and external biological threats.

  • Advances in Immunology

    • 1st Edition
    • Volume 162
    • English
    Advances in Immunology, Volume 162, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Regulatory T cells and Autoimmune Diseases

    • 1st Edition
    • Mitesh Kumar Dwivedi + 1 more
    • English
    Regulatory T Cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic applications. In particular, this book deals with various Treg-based mechanisms that can lead to autoimmune disease and covers different aspects linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies.This book specifically focuses on Treg-based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood and blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, this book covers vaccine-induced effects on the functioning of Tregs and development of CAR Treg therapy for autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. This book is carefully designed to meet the requirements of both basic and advanced researchers in the area and provide new dimensions and insight into regulatory T cells’ role in autoimmune disease pathogenesis and therapy.

  • Nucleic acid associated mechanisms in immunity and disease

    • 1st Edition
    • Volume 161
    • English
    Advances in Immunity volume 161 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advanced Vaccination Technologies for Infectious and Chronic Diseases

    A guide to Vaccinology
    • 1st Edition
    • Vasso Apostolopoulos + 2 more
    • English
    Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

  • Inmunología básica

    Funciones y trastornos del sistema inmunitario
    • 7th Edition
    • Abul K. Abbas + 2 more
    • Spanish
    Nueva edición del texto derivado de la obra de referencia en Inmunología, "Abbas, Inmunología molecular y celular" en el que se presenta de una forma concisa y visual el nivel de información adecuado para el estudiante que se enfrenta por primera vez a la asignatura. Destaca su gran riqueza y calidad iconográfica. La inclusión de tablas, esquemas, puntos clave en negrita y preguntas de autoevaluación. En cuanto a las principales novedades cabe destacar la inclusión de contenidos nuevos y ampliados sobre pandemias, COVID-19 e inmunidad de rebaño, resistencia y susceptibilidad a COVID-19, vacunas de ARN y vacunas híbridas, inmunoterapia tumoral, respuestas inmunitarias innatas a los virus, mecanismos de tolerancia inmunológica e inmunoterapia para enfermedades autoinmunes, alérgicas y otras enfermedades inflamatorias y el cáncer. La nueva edición ofrece acceso a material adicional online en inglés a través de e-book+

  • Nanomedicine in Cancer Immunotherapy

    • 1st Edition
    • Prashant Kesharwani
    • English
    Nanomedicine in Cancer Immunotherapy bridges the two disciplines of nanotechnology and immunology, summarizing the latest research into novel cancer treatments, often personalized to the patient. The book covers a wide range of nanomaterial types for use in cancer immunotherapy, including hydrogel, lipid, exosome, gold and peptide nanoparticles. The preparation, application, pros and cons of each nanomaterial class is reviewed, helping the reader understand the potential for each to tailor their own selections. Nanovaccines are also covered, along with a clinical evaluation and market analysis of nanomedicines for immunotherapy, offering an important clinical and commercial overview of this rapidly developing field.This book is an interesting reference for those working in the fields of nanotechnology, immunology, and cancer therapeutics, as well as clinicians with an interest in novel nano-based cancer treatments.

  • Molecular Biology of B Cells

    • 3rd Edition
    • Tasuku Honjo + 4 more
    • English
    Molecular Biology of B Cells, Third Edition provides a comprehensive reference on how B cells are generated, selected, activated, and engaged in antibody production. These developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. The book offers an integrated view of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. This new edition provides updated research on B cell development and function, the use of therapeutic antibodies in cancer and infectious disease, and more. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, this updated release is a definitive resource, vital for researchers across molecular biology, immunology, and genetics.

  • Infection and Autoimmunity

    • 3rd Edition
    • Naim Mahroum + 2 more
    • English
    In 2020 we lost Noel Rose, co-editor of the classic Infection and Autoimmunity. To honor and respect his work, a group of experts in the field have taken the initiative to make this book perpetual. The third edition of Infection and Autoimmunity updates all the recent and leading papers on infection and autoimmunity, in addition to a dedicated section on to the correlation between SARS-CoV-2 infection and autoimmunity. From the very beginning of the COVID-19 pandemic, numerous papers have been published, including studies conducted by the editors and authors of the book, on COVID-19 and autoimmunity, and therefore this knowledge has been incorporated into this new edition. The addition and extended coverage on SARS-CoV-2/COVID-19 and autoimmunity are pivotal for the third edition of the book due to the COVID-19 pandemic. Medical students and practitioners, as well as academic staff in medical schools globally, are enthusiastic in searching for better understanding of the correlation between infection and autoimmunity in general, and the long-term effects of SARS-CoV-2 and COVID-19 on the immunce system in particular, especially in terms of autoimmunity related to the virus.

  • Advances in Immunology

    • 1st Edition
    • Volume 160
    • English
    Advances in Immunology, Volume 160, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Advances in Immunology

    • 1st Edition
    • Volume 159
    • Frederick W. Alt + 1 more
    • English
    Advances in Immunology, Volume 159, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology with chapters covering topics such as the cGAS-STING pathway.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 160
    • English
    Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more.

  • COVID-19 Viral Sepsis

    Impact on Disparities, Disability, and Health Outcomes
    • 1st Edition
    • Uzma Syed + 1 more
    • English
    COVID-19 Viral Sepsis: Impact on Disparities, Disability, and Health Outcomes introduces the concepts of viral sepsis, its origins, and its implications. COVID-19 is a leading cause of viral sepsis with considerable impact on morbidity and mortality. Early recognition of signs and symptoms of COVID-19 can potentially impact patient outcomes.The book opens with an overview of sepsis and viral sepsis. The discussion continues with an introduction to COVID-19 and related topics on its epidemiology, diagnosis, clinical manifestations, mild to moderate disease management, and the critical care treatment of COVID-19 patients. Sequelae of COVID-19, long-term consequences, challenges, current landscape, and future preparedness round out the coverage.COVID-19 Viral Sepsis: Impact on Disparities, Disability, and Health Outcomes is a valuable resource with contributions from experts on the front line of the COVID-19 crisis providing insight and key principles in the recognition, prevention, diagnosis, and treatment of sepsis due to COVID-19.

  • Advances in Immunology

    • 1st Edition
    • Volume 158
    • Frederick W. Alt + 1 more
    • English
    Advances in Immunology, Volume 158, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Translational Neuroimmunology, Volume 8

    Multiple Sclerosis
    • 1st Edition
    • Nima Rezaei + 1 more
    • English
    Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

  • Translational Neuroimmunology, Volume 7

    Neuroinflammation
    • 1st Edition
    • Nima Rezaei + 1 more
    • English
    Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish. All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

  • Basic Immunology

    Functions and Disorders of the Immune System
    • 7th Edition
    • Abul K. Abbas + 2 more
    • English
    **Selected for 2026 Doody's Core Titles in Immunology**Meticulo... reviewed and updated for today's medical students, Basic Immunology, 7th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume has been fully revised to include recent important advances in our understanding and knowledge of the immune system. A student favorite through six outstanding editions, this new edition uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help you master this complex topic in the most efficient, effective manner possible.

  • Advances in Immunology

    • 1st Edition
    • Volume 157
    • Frederick W. Alt + 1 more
    • English
    Advances in Immunology, Volume 157, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Antigen receptor structure and signaling, T cells in the brain inflammation, The molecular mechanism of RIG-I/MDA5 activation and signaling, GSDMD biology, cGAS-STING pathway, The CARD8 inflammasome in HIV infection, and much more.

  • Epigenetic Regulation of Cancer in Response to Chemotherapy

    • 1st Edition
    • Volume 158
    • English
    Epigenetic Regulation of Cancer in Response to Chemotherapy, Volume 158 of the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting chapters on timely topics, including Epigenetically Programmed Resistance to Chemotherapy and Promotion of Immune Evasion in Cancer, A Role for the Epigenome in Cancer Cell Drug Tolerance, Histone Methylation and X Chromosomal Genes in Metastasis of Breast Cancer, Targeting Epigenetic Regulation Using Small Molecule Inhibitors, Histone Deacetylase Inhibitors as Sanguine Epigenetic Therapeutics against Pugnacious Lung Cancer, From ecology to oncology: To understand cancer stem cell dormancy, ask a Brine shrimp (Artemia), and more. Additional chapters cover Predictive Models of Chemoresistance Generated by Crunching the Public Drug Screen, Epigenomic and Genomic Profiling Datasets via Regression-, Machine Learning, and Knowledge-Based Methods, Probing on the Mechanisms of lncRNAs on Cancer Drug Resistance, Drug Tolerant Persister Cells in Cancer: Current Knowledge and Therapeutic Perspectives, and much more.

  • In Silico Approach Towards Magnetic Fluid Hyperthermia of Cancer Treatment

    Modeling and Simulation
    • 1st Edition
    • Muhammad Suleman
    • English
    In Silico Approach Towards Magnetic Fluid Hyperthermia in Cancer Treatment: Modeling and Simulation presents mathematical modeling and simulation approaches contrary to costly and time consuming in-vivo and in-vitro studies. Finite element method-based models of all hyperthermia processes of liver, brain and breast tumors are simulated on COMSOL Multiphysics software. Problems of constant versus variable heat sources, the backflow problem, the enhanced permeation and retention effect, the flow around Happel’s sphere in cells model structure, the deformation effect in poroelastic brain tumor, 3D flow through porous tissue, the reacting nanofluid flows, and optimization of parameters have been simulated for quantitative analysis. This important reference aids in hyperthermia treatment planning in clinical applications and provides an important compendium for practitioners as well as non-medical practicing scientists and engineers and is resource for both research and medical practice in hyperthermia treatment planning in clinical applications.

  • Translational Autoimmunity, Volume 6

    Advances in Autoimmune Rheumatic Diseases
    • 1st Edition
    • Nima Rezaei
    • English
    Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren’s syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell-based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource.

  • Comparative Mammalian Immunology

    The Evolution and Diversity of the Immune Systems of Mammals
    • 1st Edition
    • Ian R. Tizard
    • English
    Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism.

  • Introductory Immunology

    Basic Concepts for Interdisciplinary Applications
    • 3rd Edition
    • Jeffrey K. Actor
    • English
    **Selected for 2026 Doody's Core Titles in Immunology**Introduc... Immunology: Basic Concepts for Interdisciplinary Applications, 3rd Edition, is a completely updated, revised, and expanded concise, conceptual approach to understanding the immune systems as a primary defense to maintain health and homeostasis. This expanded version includes the aspects of microbiology and related immune defense mechanisms important in combating disease, as well critical components related to the field of vaccine development.Immunolo... as a subject is no longer confined to the realms of "immunology" or "microbiology" studies. Indeed, the subject matter has become increasingly important to understand complex mechanisms found within a wider range of biological systems. This book aims specifically at educated audiences who do not have a deep understanding of medical, biochemical, or cellular knowledge. The overall text will present concepts that portray a comprehensive picture of the natural defenses to infectious agents as well as provide an introduction to mechanisms that lead to autoimmune dysfunction. In addition, immunological diseases will be detailed, with the goal of allowing the readers to gain sufficient knowledge to make sound choices for clinical decisions to affect treatment outcomes.This new edition expands on the existing chapters, focusing on updating the previous text. It has been expanded to include knowledge on effector mechanisms addressing components inherent within cellular responses that are either newly discovered, or missing from the previous edition. It has an extra emphasis on aspects related to mechanisms important in combating microbial agents and critical sections on how vaccines protect against pathogenic invaders to limit associated pathology.The goal is that Introductory Immunology will become the preferred provider of core knowledge in immunology to build a foundation to explore components of the human immune system that work together to confer and understand dysregulation that causes clinical diseases. This book serves as a basic platform to define therapeutic interventions by: creating appreciation for components of the human immune system to work together to confer lifelong protection;providing a core knowledge in immunology to build a foundation to explore mechanisms involved in clinical disease, and defining functional aspects of immunological terms to permit the reader easy access to comprehend specific topics;presenting introduction to complex immunological concepts in a concise and easy manner that relates to clinical disease;breaking down all of immunology into manageable, logically digestible building blocks, and providing a map to explore overlapping mechanisms of immune protective responses;providing a platform to readers without medical, biochemical, or cellular expertise to understand and appreciate how immunology controls homeostasis and protects against pathogens.

  • Autoimmunity, COVID-19, Post-COVID19 Syndrome and COVID-19 Vaccination

    • 1st Edition
    • Volume 1
    • Yehuda Shoenfeld + 1 more
    • English
    Autoimmunity, COVID-19, Post-COVID-19 Syndrome and COVID-19 Vaccination covers all aspects of what is perhaps the most dramatic health crisis in the history of modern medicine. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raised major concerns about the association between the virus and various autoimmune manifestations. Over 15 distinct autoantibodies and above 10 different autoimmune diseases were found to develop in COVID-19 patients. Moreover, evidence about recovered COVID-19 patients demonstrates that persistent systemic symptoms, which are believed to have an autoimmune-related mechanism, do exist. As it is of great importance to recognize those autoimmune manifestations of COVID-19 and post-COVID-19 syndrome to properly cope with their outcomes in the ongoing pandemic and the long-term post-pandemic period, this book fulfills a vital need in the medical community.

  • Advances in Immunology

    • 1st Edition
    • Volume 156
    • English
    Advances in Immunology, Volume 156, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering self-referential immune recognition through C-type lectin receptors, genetic susceptibility to autoimmunity, activation and regulation of the cGAS-STING pathway and the implications of IL-15 trans-presentation on the immune response.

  • Allergic and Immunologic Diseases

    A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases
    • 1st Edition
    • Christopher Chang
    • English
    Allergic and Immunologic Diseases: A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases is a valuable resource for researchers in and others in the actual day to day practice of allergy and immunology, with specific information, protocols and algorithms to guide their thinking. It is not meant to be a cookbook, yet it provides practical and usable information and an explanation of why and how we do things the way we do. It also addresses limitations of testing and treatment, and how what we know and what we do not know impacts our choices. It also focuses on scientific based practices, and the known pathophysiology of allergic and immunologic diseases as well as mechanisms of action of various treatment modalities. This book is unique in that it explains the rationale behind everything we do in allergy and immunology and it offers the reader specific information on how to do procedures, order tests and treat allergic and immunologic diseases.

  • Advances in Immunology

    • 1st Edition
    • Volume 155
    • English
    Advances in Immunology, Volume 155, the latest release in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Sections of note cover B cell/GC material.

  • Allergic and Immunologic Diseases

    A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases
    • 1st Edition
    • Christopher Chang
    • English
    **Selected for Doody’s Core Titles® 2024 in Allergy/Clinical Immunology**Allergic and Immunologic Diseases: A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases is a valuable resource for researchers and others involved in the day-to-day practice of allergy and immunology, with specific information, protocols and algorithms to guide their thinking. The book provides practical information and an explanation of why and how we do things, while also addressing the limitations of testing and treatment. Other sections focus on scientific based practices and the known pathophysiology of allergic and immunologic diseases, along with mechanisms of action in various treatment modalities.This book is unique in that it explains the rationale behind everything we do in allergy and immunology, hence it offers readers specific information on procedures and how to order tests and treat allergic and immunologic diseases.

  • Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

    • 1st Edition
    • Moulay Mustapha Ennaji
    • English
    Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms.

  • Translational Autoimmunity, Volume 5

    Challenges for Autoimmune Diseases
    • 1st Edition
    • Nima Rezaei
    • English
    Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges researchers and clinicians are facing.

  • Advances in Immunology

    • 1st Edition
    • Volume 154
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 154, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering Regulatory T Cells in Infection and Factor H and Properdin and their regulation.

  • System Vaccinology

    The History, the Translational Challenges and the Future
    • 1st Edition
    • Vijay Kumar Prajapati
    • English
    Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

  • Clinical Immunology

    • 1st Edition
    • Nima Rezaei
    • English
    Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology.

  • The Paradox of the Immune System

    Protection, Chronic Inflammation, Autoimmune Disease, Cancer, and Pandemics
    • 1st Edition
    • Louis J. Catania
    • English
    The Paradox of the Immune System: Protection, Inflammation, Autoimmune Disease and Beyond provides a provocative approach to immunology as a "double-edged sword." While it is our greatest protector, it is also the cause of chronic inflammation that leads to autoimmune disease, cancer and infectious diseases like COVID-19. Sections cover the basic science of immunology and its intimate genetic associations, biomedical hypotheses asserting immunology as the basis of all human diseases, and elaborate on immunology as "the enemy within us." This engaging, original approach to a science so personal provides new and invaluable understanding on the bioscience that controls our lives.

  • Microbial Crosstalk with Immune System

    New Insights in Therapeutics
    • 1st Edition
    • Asmita Das
    • English
    Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters. Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.

  • Immunology of Recurrent Pregnancy Loss and Implantation Failure

    • 1st Edition
    • Joanna Kwak-Kim
    • English
    Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches.

  • Strategies to Mitigate the Toxicity of Cancer Therapeutics

    • 1st Edition
    • Volume 155
    • English
    Strategies to Mitigate the Toxicity of Cancer Therapeutics, Volume 155 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters, each of which is written by an international board of authors.

  • Macrophages in the Human Body

    A Tissue Level Approach
    • 1st Edition
    • Niels Olson Saraiva Camara + 1 more
    • English
    Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions.Macrophage... in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential.

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