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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

  • Inflammation and Cancer

    Mechanisms, Diagnosis, and Therapeutic Strategies
    • 1st Edition
    • Anoop Kumar + 4 more
    • English
    Inflammation and Cancer: Mechanisms, Diagnosis, and Therapeutic Strategies delves into the intricate relationship between inflammation and cancer, a crucial area of contemporary biomedical research. Sections provide an overview of inflammation's role in cancer, discussing molecular connections and signaling pathways. Chapters explore inflammatory pathways in various cancers, including breast, oral, lung, prostate, skin, and gastrointestinal cancers. The book also covers tumorigenesis, metastasis, preventive strategies, inflammatory biomarkers for cancer diagnosis, and innovative therapeutic designs. Final chapters focus on the dual role of platelets, targeting tumor-associated macrophages, novel treatment approaches, and recent advances in the field.This title offers substantial benefits to researchers, clinicians, and healthcare professionals by providing a thorough understanding of the cellular and molecular pathways linking inflammation and cancer, aiding in the development of effective anti-cancer immunotherapies. By highlighting the latest research and potential therapeutic strategies, this book serves as an essential resource for anyone dedicated to combating cancer through innovative and informed immunotherapeutic approaches.

  • The Microbiome and Cancer Treatment

    Overcoming Resistance and Enhancing Efficacy
    • 1st Edition
    • Sadhna Aggarwal + 3 more
    • English
    The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance. This knowledge can guide the development of innovative strategies to counteract drug resistance. The book also addresses the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters fosters interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. The audience can benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.

  • Immunological Aspects of Preterm Birth

    Phenotypes of Preterm Birth, Immune Mechanisms, and Pathway Forward
    • 1st Edition
    • Volume 4
    • Irina Burd MD
    • English
    Immunological Aspects of Preterm Birth: Phenotypes of Preterm Birth, Immune Mechanisms, and Pathway Forward bridges reproductive immunology of preterm birth to subtypes, phenotypes, and bedside prevention and treatment. The book reviews the role of the different immune mechanisms during pregnancy that lead to preterm birth, along with the fetal programming effects that are connected to maternal immune activation. In addition, it discusses immune cells and their products and cytokines and chemokines as central for the success of the pregnancy.While our knowledge on the role of immune cells and the inflammatory process in preterm birth has grown exponentially in the last 10 years, connecting basic science to clinical science and the development of new therapeutics has not progressed as rapidly. This book assists researchers in understanding the basic immunologic mechanisms and inflammatory processes associated with preterm birth and fills an urgent need for the development of therapeutics in this space.

  • Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments

    • 1st Edition
    • Tuan Anh Nguyen + 2 more
    • English
    Two Sides of Nanovaccines and Nanomedicines in Cancer Treatments provides a balanced exploration of the dual roles of nanotechnologies in oncology. Structured in four parts, the book begins with foundational knowledge of nanovaccines and nanomedicines, detailing their applications in cancer care and highlighting their precision in targeting cancer cells while reducing systemic toxicity. Importantly, the book addresses potential drawbacks, discussing side effects and safety concerns associated with these innovations. The final section emphasizes ethical, regulatory, and safety challenges, underscoring the need for careful oversight as nanotechnologies advance. For the academic audience, this book serves as a vital resource, offering insights that equip researchers and healthcare professionals to make informed decisions regarding clinical applications. Its focus on both the benefits and risks, alongside forward-looking perspectives, ensures that readers are well-prepared for future developments in the field of nanomedicine and cancer therapy.

  • Vaccinology and Immunizations

    • 1st Edition
    • Jahangir Moini + 2 more
    • English
    Vaccinology and Immunizations is a thorough resource on the immune system, the history of vaccines, vaccine preparation, the process of vaccine approval, and the prevention and eradication of diseases. It also includes chapters on vaccine safety and errors, and complete information on pediatric and adult immunizations. There is also discussion on elderly immunology and immunization for people who are seeking to travel abroad, as well as timely information about COVID-19.Its focus on the innate and adaptive defense systems of the body will ensure understanding of human immunity and how immunizations are effective. There is a variety of available titles related to vaccinology and immunizations, but many are now outdated. Vaccinology and Immunizations provides a new, updated resource that is widely needed, and will be welcomed by students of undergraduate, graduate and master level in vaccinology or immunology, and would also be of interest to nurses, researchers, and pharmacists.

  • Lateral Flow Assays for Rapid Point-of-care Testing

    Recent Advances, Emerging Trends, and Future Direction
    • 1st Edition
    • Seema Nara + 2 more
    • English
    The emergence and re-emergence of new infectious diseases places emphasis on the need for greater investment in rapid healthcare diagnostic solutions. As a result, lateral flow immunoassay technology is quickly evolving with new inventions. Lateral Flow Assay for Rapid Point-of-Care Testing covers today’s most significant advancements, emerging trends, and future directions linked with this technology. The book begins with a review of the format, flow, and design of old-generation lateral flow assays and the challenges impeding performance before moving into innovation in materials for rapid test strips, advances in manipulating sample flow, and the latest developments in molecular imprinting and bioconjugation techniques. Subsequent sections cover various biorecognition elements and review signal amplification as well as quantification trends. Final chapters delve into recent applications for infectious diseases detection, monitoring antibiotic resistance, multiplex detection of analytes, as well as future directions leading to the next generation of healthcare. Academicians, researchers, industrialists, and device manufacturers linked to the development of rapid and affordable point-of-care immunodiagnostics will find value in this resource.

  • Endotoxin in Critical Illness

    • 1st Edition
    • John Kellum + 1 more
    • English
    Endotoxin in Critical Illness intricately explores the theme of endotoxin and sepsis through the lenses of basic, clinical, and translational science. This work consolidates and synthesizes novel clinical insights and groundbreaking scientific discoveries into one comprehensive resource on endotoxic septic shock and sheds light on cutting-edge approaches in treatment. Beginning with a historical journey, the book traces the evolution of understanding from ancient concepts to modern molecular insights. It covers the physiological aspects of endotoxin sensitivity, tolerance, and human response variation. The crucial role of the gut microbiome in critical illness serves as a translational link between foundational science and clinical implications, and the complex language of bacterial communication is introduced, merging basic science with potential translational applications. In the clinical arena, chapters cover the critical role of endotoxin in septic shock, trauma, and its relevance in COVID-19, providing a translational bridge between laboratory findings and real-world clinical scenarios. The historical context of anti-endotoxin drug development is revisited, emphasizing the translational challenges faced in bridging basic science discoveries to clinical applications. The discussion on quantifying endotoxin concentration as well as the exploration of therapeutic rationale and clinical experiences with endotoxin removal therapy serve as a culmination of basic understanding translated into practical applications. The book concludes by contemplating the complexity of sepsis and acknowledging the challenges in achieving personalized medicine and underscoring the dynamic nature of the translational journey. In essence, this comprehensive exploration provides clinicians, researchers, and scientists with a holistic understanding of endotoxin and sepsis and potential advancements in patient care.

  • Myasthenia Gravis

    Disease, Diagnosis and Management
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    Myasthenia Gravis: Disease, Diagnosis and Management is a comprehensive resource that explores recent advancements in diagnosing and treating Myasthenia Gravis, a rare autoimmune disease affecting the neuromuscular junction. With contributions from global experts, this book addresses the increasing prevalence of Myasthenia Gravis, reflecting the latest in diagnostic techniques and novel therapies such as complement inhibitors and FcRn antagonists. It aims to support healthcare professionals in delivering optimal care through evidence-based insights and patient-centered approaches. The book is divided into several chapters, beginning with an overview of the pathogenesis and immunoregulatory defects in Myasthenia Gravis. Subsequent chapters cover diagnostic methods, non-immunosuppressiv... treatments, and biological therapies targeting the immune system. Key topics include the role of intravenous immunoglobulin (IVIg) and plasma exchange (PLEX) in severe exacerbations, thymectomy, molecular mechanisms, and the potential of hematopoietic stem cell transplants. The book also delves into precision medicine, AI applications, clinical trial considerations, and novel therapeutics like anti-FcRn antibodies. Management strategies for ocular Myasthenia Gravis, and a holistic view of living with the disease are also discussed. Myasthenia Gravis: Disease, Diagnosis and Management is invaluable for healthcare providers, physicians, immunologists, ophthalmologists, rheumatologists, physical therapists, pharmacists, and translators. It offers a modern guide to understanding and managing Myasthenia Gravis, integrating clinical expertise with the latest research to improve patient outcomes.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 168
    • English
    Advances in Cancer Research, Volume 168 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Plasticity in cell adhesion during cancer progression, AEG-1 on Cancer Drug Resistance: From Molecular Insights to Therapeutic Challenges, Multimodal AI to differentiate tumor progression from treatment effect in glioblastoma, The Role of Epigenetic Modifications in Mediating Cancer Health Disparities, In search of a targetable immune profile for acute myeloid leukemia, Notch signaling in tumorigenesis and maintenance of cancer stem cells, and much more.

  • The Immunology of the Pig

    • 1st Edition
    • Ian R. Tizard
    • English
    The Immunology of the Pig is a comprehensive and detailed exploration of the immune systems of domestic pigs, offering an invaluable resource for researchers, veterinarians, and students in the fields of immunology, veterinary medicine, and biomedical science. This text covers both the innate and adaptive immune systems of pigs, highlighting the unique features that make them an excellent model for human immune system studies. By examining the applied immunity of pigs, including available vaccines and immune-mediated diseases, this book addresses a critical need for understanding porcine immunology in both agricultural and biomedical contexts. The book is meticulously structured to cover a wide range of topics. It begins with the evolutionary origins and domestication of pigs, providing a historical context that enriches the understanding of their immune systems. Subsequent chapters explore key aspects of porcine immunology, including piglet ontogeny, reproduction, and lactation; innate immunity; hematology; cytokine functions; antigen processing cells; and lymphoid organs. Detailed discussions on the major histocompatibility complex, innate lymphoid cells, B and T cell systems, and immunity on body surfaces offer a thorough insight into the complex mechanisms at play. Additionally, the text addresses the microbiota's role, vaccination strategies, and immunity to various bacterial, viral, and parasitic diseases, rounding out a holistic view of porcine immune health.The Immunology of the Pig is an essential reference for anyone involved in veterinary science, immunology, or biomedical research. It provides a deep dive into the pig's immune system, presenting a wealth of information that is both scientifically rigorous and practically applicable. By understanding the parallels between porcine and human immune systems, researchers can leverage this knowledge to advance medical science, particularly in the areas of xenotransplantation and disease modeling. This book is a vital tool for advancing our understanding of immunology and improving health outcomes for both pigs and humans.

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