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Books in Drug discovery

Elsevier's Drug Delivery collection is an indispensable resource for scientists and researchers in the pharmaceutical field, exploring the administration of pharmaceutical compounds for therapeutic effects from molecule identification to medication development. It provides comprehensive coverage, including crucial aspects such as drug screening, medicinal chemistry, and preclinical safety assessments. Highlighting emerging trends like precision medicine, AI applications, immunotherapy, and innovative delivery systems, the collection offers insights into the latest advancements and their impact on healthcare.

BooksJournals

    • Intelligent Nanobiosystems in Medicine and Healthcare, Volume 1

      • 1st Edition
      • March 28, 2025
      • Vijay Mishra + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 2 5 2 6
      • eBook
        9 7 8 0 3 2 3 9 0 2 5 3 3
      Intelligent Nanobiosystems in Medicine and Healthcare, Volume One: Fundamentals, Fabrication and Commercialization provides an overview of recent progress in the nanobiosystems arena, helping readers design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancement in cutting-edge nanomedical technologies. It highlights established research and technology on intelligent nanobiosystems, their rapidly emerging aspects, and future research directions. Sections cover nanobiosystems, explore nano candidates and fabrication aspects, and delve into the challenges of commercialization.Th... book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, biochemical and biomedical engineers working both in academia and industry.

    • Privileged Scaffolds in Drug Discovery

      • 1st Edition
      • July 19, 2023
      • Bin Yu + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 6 1 1 0
      • eBook
        9 7 8 0 4 4 3 1 8 6 1 2 7
      Privileged Scaffolds in Drug Discovery is the most complete and up-to-date work in the area. Covering a wide range of privileged structures, it is a perfect reference for scientists involved in targeted drug development.The editors recruited experts from several prestigious Chinese institutions to cover the areas of antiviral drugs, chalcone, pyrimidine, (benz)imidazoles, natural product-derived privileged scaffolds, N-Sulfonyl carboxamides, kinase inhibitors, antitumor molecules, antineurodegenerativ... drugs, triazoles, oxazolidinone, indole and indoline scaffolds, tigliane diterpenoids, peptide and peptide-based drugs, quassinoids, and others including pseudonatural products, macrocycles, stable peptides and peptidomimetics. The book also explores scaffolds in drug molecules approved in recent years.Privileged Scaffolds in Drug Discovery is a complete reference for researchers in drug discovery and organic synthesis, in academic and corporate settings, who are investigating privileged structures upon which to base new drugs. Researchers in medicinal chemistry and chemical biology will also find the contents of this book valuable.

    • Managing the Drug Discovery Process

      • 2nd Edition
      • March 9, 2023
      • Susan Miller + 5 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 3 0 4 6
      • eBook
        9 7 8 0 1 2 8 2 4 3 0 5 3
      Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharma... industry.

    • Nanotherapeutics in Cancer Vaccination and Challenges

      • 1st Edition
      • March 3, 2022
      • Mahfoozur Rahman + 4 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 6 8 6 4
      • eBook
        9 7 8 0 1 2 8 2 3 6 8 7 1
      Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects. Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy.

    • Herbal Bioactive-Based Drug Delivery Systems

      • 1st Edition
      • March 13, 2022
      • Inderbir Singh Bakshi + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 3 8 5 5
      • eBook
        9 7 8 0 3 2 3 8 5 9 1 0 3
      Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

    • Antioxidants Effects in Health

      • 1st Edition
      • June 16, 2022
      • Seyed Mohammad Nabavi + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 0 9 6 8
      • eBook
        9 7 8 0 1 2 8 1 9 0 9 7 5
      Antioxidants Effects in Health: The Bright and the Dark Side examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants’ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.

    • Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences

      • 1st Edition
      • May 21, 2021
      • Navneet Sharma + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 7 4 8 1
      • eBook
        9 7 8 0 1 2 8 2 1 7 4 7 4
      Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process. This book will be useful to pharmaceutical science researchers and students who need basic knowledge of computational techniques relevant to their projects. Bioscientists, bioinformaticians, computational scientists, and other stakeholders from industry and academia will also find this book helpful.

    • Cancer-Leading Proteases

      • 1st Edition
      • January 9, 2020
      • Satya Prakash Gupta
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 1 6 8 3
      • eBook
        9 7 8 0 1 2 8 1 8 1 6 9 0
      Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases.

    • Drug Discovery Targeting Drug-Resistant Bacteria

      • 1st Edition
      • May 15, 2020
      • Prashant Kesharwani + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 4 8 0 6
      • eBook
        9 7 8 0 1 2 8 1 8 4 8 1 3
      Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful.

    • Multi-Scale Approaches in Drug Discovery

      • 1st Edition
      • February 14, 2017
      • Alejandro Speck-Planche
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 1 2 9 4
      • eBook
        9 7 8 0 0 8 1 0 1 2 4 2 0
      Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computat... methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents. After an introduction to multi-scale approaches outlining the need for and benefits of their use, the book goes on to explore a range of useful techniques and research areas, and their potential applications to this process. Profiling drug binding by thermodynamics, machine learning for predicting enzyme sub-classes, and multitasking models for computer-aided design and virtual compound screening are discussed, before the book goes on to review Alkaloid Menispermaceae leads, natural chemotherapeutic agents and methods for speeding up the design and virtual screening of therapeutic peptides. Flavonoids as multi-target compounds are then explored, before the book concludes with a review of Quasi-SMILES as a novel tool. Collecting together reviews and original research contributions written by leading experts in the field, Multi-Scale Approaches to Drug Discovery highlights cutting-edge approaches and practical examples of their implementation for those involved in the drug discovery process at many different levels. Using the combined knowledge of medicinal, computational, pharmaceutical and bio- chemists, it aims to support growth in the multi-scale approach to promote greater success in the development of new drugs.