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Pharmacology

Principles and Practice

  • 1st Edition - June 19, 2009
  • Latest edition
  • Authors: Miles Hacker, William S. Messer, Kenneth A. Bachmann
  • Language: English

Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as… Read more

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Description

Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine.

While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers.

The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process.

The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research.

Key features

  • Uses individual drugs to explain molecular actions
  • Full color art program explains molecular and chemical concepts graphically
  • Logical structure reflecting the current state of pharmacology and translational research
  • Covers such intricacies as drug resistance and cell death
  • Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Readership

Advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools who want a solid introduction to the basic science of pharmacology and envision careers in drug research

Table of contents

TABLE OF CONTENTS:

1. Routes of Administration

2. Membranes and Drug Action

3. Drug Absorption

4. Drug Transporters in ADME

5. Drug Distribution

6. Drug Metabolism

7. Drug Excretion

8. Pharmacokinetics

9. Receptor-ligand Interaction

10. Molecular Targets for Drug Actions

11. Cell Signaling Pathways

12. Immunopharmacology

13. Drug Toxicity

14. Adverse Drug Reactions

15. Cell Death

16. Pharmacogenomics and Pharmacogenetics

17. Drug Tolerance, Dependence, Addiction

18. Drug Resistance

19. Role of Molecular Biology in Modern Pharmacology

20. Drug Discovery – Sources of New Drugs

21. Drug Development – Pre-clinical

22. Drug Development – Clinical

23. Nutriceuticals

24. The FDA

Product details

  • Edition: 1
  • Latest edition
  • Published: June 19, 2009
  • Language: English

About the authors

MH

Miles Hacker

Affiliations and expertise
The University of Toledo College of Pharmacy, Ohio, USA

WM

William S. Messer

Affiliations and expertise
The University of Toledo College of Pharmacy, Ohio, USA

KB

Kenneth A. Bachmann

Affiliations and expertise
The University of Toledo College of Pharmacy, Ohio, USA

View book on ScienceDirect

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