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Elsevier Science

  • Regression Analysis Study Guide

    • 2nd Edition
    • Rudolf J. Freund + 2 more
    • English
  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 44
    • F.D. King + 1 more
    • English
    The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biote... industry as escalating R&D costs are not being matched by increased output. Few observers doubt that selecting the right targets, ie those which are critical to disease pathology and are ‘druggable’, is the best starting point for improved productivity.The seven chapters of this volume describe recent progress towards drugs acting at a range of ‘druggable’ targets. One chapter addresses kinases, one covers an ion channel, two proteases are featured and three of the chapters cover G-protein coupled receptors, which has historically perhaps been the most fruitful area for medicinal chemists.
  • Materials Surface Processing by Directed Energy Techniques

    • 1st Edition
    • Yves Pauleau
    • English
    The current status of the science and technology related to coatings, thin films and surface modifications produced by directed energy techniques is assessed in Materials Surface Processing by Directed Energy Techniques. The subject matter is divided into 20 chapters - each presented at a tutorial level – rich with fundamental science and experimental results. New trends and new results are also evoked to give an overview of future developments and applications.
  • Hydrodynamic Fluctuations in Fluids and Fluid Mixtures

    • 1st Edition
    • Jose M. Ortiz de Zarate + 1 more
    • English
    This book deals with density, temperature, velocity and concentration fluctuations in fluids and fluid mixtures. The book first reviews thermal fluctuations in equilibrium fluids on the basis of fluctuating hydrodynamics. It then shows how the method of fluctuating hydrodynamics can be extended to deal with hydrodynamic fluctuations when the system is in a stationary nonequilibrium state. In contrast to equilibrium fluids where the fluctuations are generally short ranged unless the system is close to a critical point, fluctuations in nonequilibrium fluids are always long-ranged encompassing the entire system. The book provides the first comprehensive treatment of fluctuations in fluids and fluid mixtures brought out of equilibrium by the imposition of a temperature and concentration gradient but that are still in a macroscopically quiescent state. By incorporating appropriate boundary conditions in the case of fluid layers, it is shown how fluctuating hydrodynamics affects the fluctuations close to the onset of convection. Experimental techniques of light scattering and shadowgraphy for measuring nonequilibrium fluctuations are elucidated and the experimental results thus far reported in the literature are reviewed.
  • Carbon Nanotechnology

    Recent Developments in Chemistry, Physics, Materials Science and Device Applications
    • 1st Edition
    • Liming Dai
    • English
    Nanotechnology is no longer a merely social talking point and is beginning to affect the lives of everyone. Carbon nanotechnology as a major shaper of new nanotechnologies has evolved into a truly interdisciplinary field, which encompasses chemistry, physics, biology, medicine, materials science and engineering. This is a field in which a huge amount of literature has been generated within recent years, and the number of publications is still increasing every year. Carbon Nanotechnology aims to provide a timely coverage of the recent development in the field with updated reviews and remarks by world-renowned experts. Intended to be an exposition of cutting-edge research and development rather than a kind of conference proceeding, Carbon Nanotechnology will be very useful not only to experienced scientists and engineers, who wish to broaden their knowledge of the wide-ranging nanotechnology and/or to develop practical devices, but also to graduate and senior undergraduate students who look to make their mark in this field of the future.
  • Footprints in the Soil

    People and Ideas in Soil History
    • 1st Edition
    • Benno P Warkentin
    • English
    The history of science discipline is contributing valuable knowledge of the culture of soil understanding, of the conditions in society that fostered the ideas, and of why they developed in certain ways. This book is about the progressive “footprints” made by scientists in the soil. It contains chapters chosen from important topics in the development of soil science, and tells the story of the people and the exciting ideas that contributed to our present understanding of soils. Initiated by discussions within the Soil Science Society of America and the International Union of Soil Sciences, this book uniquely illustrates the significance of soils to our society. It is planned for soils students, for various scientific disciplines, and for members of the public who show an increasing interest in soil. This book allows us to answer the questions: “How do we know what we know about soils?” and “How did one step or idea lead to the next one?”The chapters are written by an international group of authors, each with special interests, bound together by the central theme of soils and how we came to our present understanding of soils. Each concentrate on soil knowledge in the western world and draw primarily on written accounts available in English and European languages. Academics, graduate students, researchers and practitioners will gain new insights from these studies of how ideas in soil science and understanding of uses of soils developed.
  • Electricity Market Reform

    An International Perspective
    • 1st Edition
    • Fereidoon Sioshansi + 1 more
    • English
    Since the late 1980s, policy makers and regulators in a number of countries have liberalized, restructured or “deregulated” their electric power sector, typically by introducing competition at the generation and retail level. These experiments have resulted in vastly different outcomes - some highly encouraging, others utterly disastrous. However, many countries continue along the same path for a variety of reasons. Electricity Market Reform examines the most important competitive electricity markets around the world and provides definitive answers as to why some markets have performed admirably, while others have utterly failed, often with dire financial and cost consequences. The lessons contained within are direct relevance to regulators, policy makers, the investment community, industry, academics and graduate students of electricity markets worldwide.
  • Design Aspects of Used Lubricating Oil Re-Refining

    • 1st Edition
    • Firas Awaja + 1 more
    • English
    Design Aspects of Used Lubricating Oil Re-Refining presents a feasible and comprehensive technology for recycling of used lubricating oils. This book discusses efficient and effective ways of reusing lubricating oil which, if implemented, will result in a better quality of life, the stability of the environment, the health of national economies and better relationships between nations. It presents essential experimental results for process designers and engineers to establish a complete process design. The conditions and behaviour in each step in the re-refining process, (dehydration, solvent extraction, solvent stripping, and vacuum distillation) are examined in order to discover ways to recover and reuse wastes that are produced by lubricating oils.
  • Early Intervention for Autism Spectrum Disorders

    A Critical Analysis
    • 1st Edition
    • Volume 1
    • Johnny L. Matson + 1 more
    • English
    Early Intervention for Autism Spectrum Disorders is the first in a series aimed at addressing the rapidly expanding field of assessment and treatment of children with mental health issues and/or development disabilities. Early Intervention for Autism Spectrum Disorders is aimed at the researcher of practitioner who works with those young children with Autism Spectrum Disorder. In addition to covering major research developments in differential diagnosis and early intervention, the author's provide a critical review and analysis of core concept that define this area. The first chapter of the book reviews the development of definitions of autism along with early methods for diagnosing this area of developmental disabilities. Chapter two covers some of the most discussed theories of etiology along with a review of prevalence and the author's opinions on why the number of children diagnosed with autism spectrum disorder has increased markedly in recent years. A chapter on the most commonly used assessment methods and a critique of the psychometric properties of each is followed by three chapters on treatment. We have broken the treatment chapters down based on type of intervention. The first treatment chapter covers specific target behaviors or small sets of behaviors. A second chapter covers training for the packaged comprehensive treatment models with particular emphasis on the TEACCH, UCLA-YAP and the University of California Santa Barbara Autism Research and Training Program. Each of these programs gives a unique perspective on treatment for these young children. The final treatment chapter covers the recent developments in pharmacotherapy for autism spectrum disorder, with a critical analysis and review of the data. We hope the overview presented proves to be of interest to researchers and practitioners in the field. We present one perspective on this exciting and innovative area of research and treatment. Hopefully, it will serve as one useful source to those who wish to provide the most up to date evidence based intervention to these young developmentally challenged children.
  • Principles of Sequence Stratigraphy

    • 1st Edition
    • Octavian Catuneanu
    • English
    Principles of Sequence Stratigraphy provides an in-depth coverage and impartial assessment of all current ideas and models in the field of sequence stratigraphy. This textbook thoroughly develops fundamental concepts of sequence stratigraphy that links base-level changes to sedimentary deposits. It examines differing approaches to how the sequence stratigraphic method can be applied to the rock record, and reviews practical applications such as how petroleum geologists can target where to drill for oil. The book's balanced approach helps students acquire a common terminology and conceptual understanding that will be helpful later in their academic and professional careers, whether they pursue jobs as geologists, geophysicists, or reservoir engineers. This textbook offers theoretical guidelines of how the facies and time relationships are expected to be under specific circumstances such as subsidence patterns, sediment supply, topographic gradients, etc. It goes beyond the standard treatment of sequence stratigraphy by focusing on a more user-friendly and flexible method of analysis of the sedimentary rock record than other current methods. The text is richly illustrated with dozens of full color photographs and original illustrations of outcrop, core, well log, and 3D seismic data. There is a dedicated chapter on discussions and conclusions, along with an instructor site containing images from the book. Principles of Sequence Stratigraphy will appeal to researchers and professionals, as well as upper graduate and graduate students in stratigraphy, sedimentology, petroleum peology and engineering, economic geology, coal geology, seismic exploration, precambrian geology, and mining geology and engineering.