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Elsevier

Elsevier Science

  • Palladium in Heterocyclic Chemistry

    A Guide for the Synthetic Chemist
    • 2nd Edition
    • Jie Jack Li + 1 more
    • English
    Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium chemistry to the syntheses of heterocycles has grown exponentially. These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of Palladium in Heterocyclic Chemistry is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 1. Palladium chemistry of heterocycles has its "idiosyncrasies" stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of &agr and &bgr activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called "heteroaryl Heck reaction". For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 2. A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containi... natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field. We also hope this book will spur more interest and inspire ideas in such an extremely useful area. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle. The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles. Many heterocycle-containi... natural products (highlighted throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry keeps readers abreast of this fast-growing field. It is also hoped that this book will stimulate more interest and inspire new ideas in this exciting field.

  • Elsevier's Dictionary of Chemoetymology

    The Whys and Whences of Chemical Nomenclature and Terminology
    • 1st Edition
    • Alexander Senning
    • English
    Noting a marked lack of comprehensiveness and/or contemporaneity among typical reference works on chemical etymology, as well as a somewhat spotty coverage of chemical terms and their etymology in comprehensive dictionaries and textbooks the author decided to write an up-to-date desk reference on chemical etymology which would satisfy the needs of casual readers as well as those of more demanding users of etymological lore. Characteristic user-friendly features of the present work include avoidance of cumbersome abbreviations, avoidance of entries in foreign alphabets, and a broad coverage of all chemical disciplines including mineralogy. Biological, medical, geological, physical and mathematical terms are only considered where they appear of interest to mainstream chemists.This book does not provide definitions of terms (unless required in the etymological context) nor guidance as to the timeliness of different nomenclature systems. The typical user will from the outset be well aware of the exact meaning of the terms he or she focuses on and only require the etymological background to be used. Examples of sources which have been drawn upon in the preparation of this book, apart from the extremely useful Internet resource Google, are listed, but an exhausting enumeration would be tiresome and impractical..

  • Reprogramming the Brain

    • 1st Edition
    • Volume 157
    • Aage R. Moller
    • English
    The brain is plastic and it can change its function to adapt to changing demands of various kinds. The brain can also re-organize and change its function to better utilize its resources when parts of the brain have been damaged through injuries and diseases. This means that the brain is not “hard wired” but can be reprogrammed when needed. This book describes different aspects of how the plasticity can become activated and how it can benefit the individual person. This book provides in-depth coverage of many important aspects of neural plasticity and how it applies to trauma, including strokes and disorders of the central nervous system that affect memory and cognition. The book also discusses how neural plasticity is involved in aphasia, pain and tinnitus. The roles of neural plasticity in motor rehabilitation and in adaptation to prostheses such as cochlear and cochlear nucleus implants are also topics of the book.

  • Electromagnetic Compatibility in Power Systems

    • 1st Edition
    • Francesco Lattarulo
    • English
    A large amount of natural or artificially produced physical phenomena are exploited for practical applications, even though several of them give rise to unpleasant consequences. These ultimately manifest themselves under form of malfunction or definitive failure of components and systems, or environmental hazard. So far, manifold categories of inadvertent or deliberate sources have been discovered to simultaneously produce useful effects in some ways but adverse ones in others. In particular, responsible for the growing interest in the last decades for Electromagnetic Compatibility (EMC) has been the progressive miniaturisation and sensitivity of electronic components and circuits, often operating in close proximity to relatively powerful sources of electromagnetic interference. Potential authors of books on the subject-matter are fully aware of the fact that planning production of manageable handbooks capable to treat all the EMC case studies of practical and long-lasting interest could result in a questionable and difficult undertaking. Therefore, in addition to textbooks providing a thorough background on basic aspects, thus being well-tailored for students and those which want to get in contact with this discipline, the most can be made to jointly sustain a helpful and practicable publishing activity is to supply specialised monographs or miscellanies of selected topics. Such resources are preferentially addressed to post-graduate students, researchers and designers, often employed in the forefront of research or engaged for remodelling design paradigms. Hence, the prerequisite for such a class of publications should consist in arousing critical sense and promoting new ideas. This is the object of Electromagnetic Compatibility in Power Systems, which tries to rather discuss special subjects, or throw out suggestions for reformulating conventional approaches, than to appear as a reference text. A common motivation encouraged the contributors to bringing together a number of accounts of the research that they have undertaken over the late years: willing to fill the important need of covering EMC topics rather proper to transmission and distribution of electric power than, more usually, to Electronics and Telecommunication Systems.

  • Chemical Product Design: Towards a Perspective through Case Studies

    • 1st Edition
    • Volume 23
    • Ka M. Ng + 2 more
    • English
    Chemical Product Design: Towards a Perspective through Case Studies provides a framework for chemical product design problems which are clearly defined together with different solution approaches. This book covers the latest methods and tools currently available in the field and discusses future challenges that the chemical industry is faced with. It focuses on important issues of chemical product design and provides a good overview on industrial chemical product design problems through case studies supplied by leading experts. The editors of Chemical Product Design teach chemical product design at graduate level courses and also serve as consultants for various chemical companies. They have also developed experimental techniques for chemical product design as well as computer-aided design methods and tools.

  • Molecular and Nano Electronics: Analysis, Design and Simulation

    • 1st Edition
    • Volume 17
    • Jorge M. Seminario
    • English
    The aim of Molecular and Nano Electronics: Analysis, Design and Simulation is to draw together contributions from some of the most active researchers in this new field in order to illustrate a theory guided-approach to the design of molecular and nano-electronics. The field of molecular and nano-electronics has driven solutions for a post microelectronics era, where microelectronics dominate through the use of silicon as the preferred material and photo-lithography as the fabrication technique to build binary devices (transistors). The construction of such devices yields gates that are able to perform Boolean operations and can be combined with computational systems, capable of storing, processing, and transmitting digital signals encoded as electron currents and charges. Since the invention of the integrated circuits, microelectronics has reached increasing performances by decreasing strategically the size of its devices and systems, an approach known as scaling-down, which simultaneously allow the devices to operate at higher speeds.

  • Event-Related Dynamics of Brain Oscillations

    • 1st Edition
    • Volume 159
    • Christa Neuper + 1 more
    • English
    Research on brain oscillations and event-related electroencephalograp... (EEG) and event-related (de-) synchronization (ERD/ERS) in particular became a rapidly growing field in the last decades. A large number of laboratories worldwide are using ERD/ERS to study cognitive and motor brain function and the importance of this tool in neurocognitive research is widely recognized. This book is a summary of the most current research, methods, and applications of the study of event-related dynamics of brain oscillations. Facing the rapid progress in this field, it brings together, on the one side, fundamental questions of the underlying events, which still remain to be clarified and, on the other side, some of the most significant novel findings, which point to the key topics for future research. In particular, the chapters of this volume cover the neurophysiological fundamentals and models (Section I), new methodological approaches (Section II), current ERD research related to cognitive (Section III) and sensorimotor brain function (Section IV), invasive approaches and clinical applications (Section V), and novel developments of EEG-based brain-computer interfaces and neurofeedback (Section IV).

  • Palladium in Heterocyclic Chemistry

    A Guide for the Synthetic Chemist
    • 2nd Edition
    • Volume 26
    • Jie Jack Li + 1 more
    • English
    Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium chemistry to the syntheses of heterocycles has grown exponentially. These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of the book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 1. Palladium chemistry of heterocycles has its “idiosyncrasies” stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of &agr and &bgr activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called "heteroaryl Heck reaction". For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 2. A myriad of heterocycles are biologically active and therefore of paramount importance to medicinal and agricultural chemists. Many heterocycle-containi... natural products (they are highlighted in boxes throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry will keep readers abreast of such a fast-growing field. We also hope this book will spur more interest and inspire ideas in such an extremely useful area. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle. The large body of data regarding palladium-mediated polymerization of heterocycles in material chemistry is not focused here; neither is coordination chemistry involving palladium and heterocycles. Many heterocycle-containi... natural products (highlighted throughout the text) have elicited great interest from both academic and industrial research groups. Recognizing the similarities between the palladium chemistry of arenes and heteroarenes, a critical survey of the accomplishments in heterocyclic chemistry keeps readers abreast of this fast-growing field. It is also hoped that this book will stimulate more interest and inspire new ideas in this exciting area.

  • Proceedings from the International Conference on Advances in Engineering and Technology (AET2006)

    • 1st Edition
    • Jackson Mwakali
    • English

  • Topics on System Analysis and Integrated Water Resources Management

    • 1st Edition
    • Andrea Castelletti + 1 more
    • English
    The Integrated Water Resources Management (IWRM) paradigm has been worldwide recognized as the only feasible way currently available to ensure a sustainable perspective in planning and managing water resource systems. It is the inspiring principle of the Water Framework Directive, adopted by the European Union in 2000, as well as the main reference for all the water related activity of UNESCO in the third world countries. However, very often, real world attempts of implementing IWRM fail for the lack of a systematic approach and the inadequacy of tools and techniques adopted to address the intrinsically complex nature of water systems. This book explores recent and important contributions of System Analysis and Control Theory to the technical application of such paradigm and to the improvement of its theoretical basis. Its prior aim is to demonstrate how the modelling and computational difficulties posed by this paradigm might be significantly reduced by strengthening the efficiency of the solution techniques, instead of weakening the integration requirements. The first introductory chapter provides the reader with a logical map of the book, by formalizing the IWRM paradigm in a nine-step decisional procedure and by identifying the points where the contribution of System Analysis and Control Theory is more useful. The book is then organized in three sections whose chapters analyze some theoretical and mathematical aspects of these contributions or presents design applications. The outstanding research issues on the border between System Analysis and IWRM is depicted in the last chapter, where a pull of scientists and experts, coordinated by Prof. Tony Jakeman describe the foreseeable scenario. The book is based on the most outstanding contributions to the IFAC workshop on Modelling and Control for Participatory Planning and Managing Water Systems held in Venice, September 28- October 1, 2004. That workshop has been conceived and organized with the explicit purpose of producing this book: the maximum length of the papers was unusually long (of the size of a book chapter) and only five long oral presentations were planned each day, thus allowing for a very useful and constructive discussion.

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