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Academic Press

  • Nonviral Vectors for Gene Therapy

    Lipid- and Polymer-based Gene Transfer
    • 1st Edition
    • Volume 88
    • English
    The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

  • Soil Microbiology, Ecology and Biochemistry

    • 4th Edition
    • Eldor Paul
    • English
    The fourth edition of Soil Microbiology, Ecology and Biochemistry updates this widely used reference as the study and understanding of soil biota, their function, and the dynamics of soil organic matter has been revolutionized by molecular and instrumental techniques, and information technology. Knowledge of soil microbiology, ecology and biochemistry is central to our understanding of organisms and their processes and interactions with their environment. In a time of great global change and increased emphasis on biodiversity and food security, soil microbiology and ecology has become an increasingly important topic. Revised by a group of world-renowned authors in many institutions and disciplines, this work relates the breakthroughs in knowledge in this important field to its history as well as future applications. The new edition provides readable, practical, impactful information for its many applied and fundamental disciplines. Professionals turn to this text as a reference for fundamental knowledge in their field or to inform management practices.

  • Advances in Bacterial Pathogen Biology

    • 1st Edition
    • Volume 65
    • English
    This volume is an up-to-date overview of the physiology of selected pathogenic bacteria. Each chapter is written by experts in the field of that organism.The focus is on biochemistry and physiology but topics of clinical relevance are included.

  • Mitochondrial Function

    • 1st Edition
    • Volume 547
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Methods to assess mitochondrial function is of great interest to neuroscientists studying chronic forms of neurodegeneration, including Parkinson's, Alzheimer's, ALS, Huntington's and other triplet repeat diseases, but also to those working on acute conditions such as stroke and traumatic brain injury. This volume covers research methods on how to assess the life cycle of mitochondria including trafficking, fusion, fission, and degradation. Multiple perspectives on the complex and difficult problem of measurement of mitochondrial reactive oxygen species production with fluorescent indicators and techniques ranging in scope from measurements on isolated mitochondria to non-invasive imaging of metabolic function.

  • Bioenergy

    Biomass to Biofuels
    • 1st Edition
    • Anju Dahiya
    • English
    Depleting fossil fuel reserves and adverse effects of fluctuating oil prices have renewed interest in alternative and sustainable sources of energy. Bioenergy: Biomass to Biofuels takes on this topic and examines current and emerging feedstocks and advanced processes and technologies enabling the development of all possible alternative energy sources: solid (wood energy, grass energy, and other biomass), liquid (biodiesel, algae biofuel, ethanol), and gaseous/electric (biogas, syngas, bioelectricity). Divided into seven parts, Bioenergy gives thorough consideration to topics such as feedstocks, biomass production and utilization, life cycle analysis, Energy Return on Invested (EROI), integrated sustainability assessments, conversions technologies, biofuels economics and policy. In addition, contributions from leading industry professionals and academics, augmented by related service-learning case studies and quizzes, provide readers with a comprehensive resource that connect theory to real-world implementation.

  • Navigating the Business Loan

    Guidelines for Financiers, Small-Business Owners, and Entrepreneurs
    • 1st Edition
    • Morton Glantz
    • English
    The need for "back to basics" information about credit risk has not disappeared; in fact, it has grown among lenders and investors who have no easy ways to learn about their clients. This short and readable book guides readers through core risk/performance issues. Readers learn the ways and means of running more efficient businesses, review bank and investor requirements as they evaluate funding requests, gain knowledge selling themselves, confidence in business plans, and their ability to make good on loans. They can download powerful tools such as banker’s cash flow models and forecast equations programmable into a cell or tablet. Readers can punch keys to ascertain financial needs, calculate sales growth rates calling for external financing, profits required to internally finance their firms, and ways to position revenue growth rates in equilibrium with their firm’s capital structure – a rock-solid selling point among smart lenders and investors. The book’s "how-to," practical and systematical guide to credit and risk analysis draws upon case studies and online tools, such as videos, spreadsheets, and slides in providing a concise risk/return methodology.

  • Elements of Petroleum Geology

    • 3rd Edition
    • Richard C. Selley + 1 more
    • English
    This Third Edition of Elements of Petroleum Geology is completely updated and revised to reflect the vast changes in the field since publication of the Second Edition. This book is a usefulprimer for geophysicists, geologists, and petroleum engineers in the oil industry who wish to expand their knowledge beyond their specialized area. It is also an excellent introductory text for a university course in petroleum geoscience.Elements of Petroleum Geology begins with an account of the physical and chemical properties of petroleum, reviewing methods of petroleum exploration and production. These methods include drilling, geophysical exploration techniques, wireline logging, and subsurface geological mapping. After describing the temperatures and pressures of the subsurface environment and the hydrodynamics of connate fluids, Selley examines the generation and migration of petroleum, reservoir rocks and trapping mechanisms, and the habit of petroleum in sedimentary basins. The book contains an account of the composition and formation of tar sands and oil shales, and concludes with a brief review of prospect risk analysis, reserve estimation, and other economic topics.

  • Practical Guide to Clinical Computing Systems

    Design, Operations, and Infrastructure
    • 2nd Edition
    • Thomas Payne
    • English
    Although informatics trainees and practitioners who assume operational computing roles in their organization may have reasonably advanced understanding of theoretical informatics, many are unfamiliar with the practical topics - such as downtime procedures, interface engines, user support, JCAHO compliance, and budgets - which will become the mainstay of their working lives. Practical Guide to Clinical Computing Systems 2nd edition helps prepare these individuals for the electronic age of health care delivery. It is also designed for those who migrate into clinical computing operations roles from within their health care organization. A new group of people interested in this book are those preparing for Clinical Informatics board certification in the US. The work provides particular differentiation from the popular first edition in four areas: 40% more content detailing the many practical aspects of clinical informatics. Addresses the specific needs of the Clinical Informatics board certification course – for which it is presently recommended by the ABPM Focus on new tech paradigms including cloud computing and concurrency – for this rapidly changing field.

  • Clinical Genomics

    • 1st Edition
    • Shashikant Kulkarni + 1 more
    • English
    Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging regulatory issues that will govern clinical use of NGS, and reimbursement paradigms that will affect the way in which laboratory professionals get paid for the testing.

  • Metagenomics for Microbiology

    • 1st Edition
    • Jacques Izard + 1 more
    • English
    Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future.

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