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Elsevier

Academic Press

  • DNA and Chromatin Damage Caused by Radiation

    • 1st Edition
    • John T. Lett + 1 more
    • English
    Advances in Radiation Biology, Volume 17: DNA and Chromatin Damage Caused by Radiation outlines the different biological reactions to radiation. This book discusses the linear energy transfer and energy loss; DNA breaks and track structure; DNA radicals from water radicals; and radiation-induced strand breaks in isolated DNA. The radiation damage to DNA and its nearby environment; thiol radioprotectors and mechanism of action; radiolysis of water and track reactions; and computer simulation of higher order structure of DNA are also elaborated. This publication likewise covers the concept of chromatin structure; DNA supercoiling studied by sedimentation; measurement of radiation-induced DNA breakage; and analysis of damage in interphase cells. This volume is a useful reference to biologists and students concerned with DNA and chromatin damage caused by radiation.

  • Advances in Radiation Biology

    Volume 1
    • 1st Edition
    • Leroy G. Augenstein + 2 more
    • English
    Advances in Radiation Biology, Volume 1, provides an overview of the state of knowledge in radiation biology. The book contains six chapters and opens with a review some of the recent work bearing on the nature of the radicals produced in water and on the rates of some of the reactions of the radicals. It also comments on some of the applications of the radical model which have been made. These are followed by a chapter on the process of photosynthesis, covering light absorption and emission by pigments, electromagnetic energy transfer among and between pigment molecules, and the (physical) transfer and migration of electronic charge. Subsequent chapters deal with the effects of tritium irradiation on cells; the effects of small doses of ionizing radiation; the radiation chemical reactions of the amino acids; and the nature of temperature effects on enzyme inactivation by various radiations.

  • Insect Molecular Genetics

    An Introduction to Principles and Applications
    • 1st Edition
    • Marjorie A. Hoy
    • English
    Developed as an introduction to new molecular genetic techniques, Insect Molecular Genetics also provides literature, terminology, and additional sources of information to students, researchers, and professional entomologists.Althou... most molecular genetics studies have employed Drosophila, this book applies the same techniques to other insects, including pest insects of economic importance.As a text, as a reference, as a primer, and as a review of a vast and growing literature, Insect Molecular Genetics is a valuable addition to the libraries of entomologists, geneticists, and molecular biologists.

  • Annual Reports in Organic Synthesis–1984

    Annual Reports in Organic Synthesis
    • 1st Edition
    • Martin J. O'Donnell + 1 more
    • English
    Annual Reports in Organic Synthesis—1984 is a bibliography of papers on organic synthesis from primary chemistry journals. Topics covered range from carbon-carbon bond forming reactions to oxidations, reductions, synthesis of heterocycles, and synthetic preparations. This book consists of seven chapters and begins with a list of papers on carbon-carbon bond forming reactions, including carbon-carbon single, double, and triple bonds. The chapters that follow focus on oxidations and reductions, methods of synthesizing heterocyclic systems, and the use of protecting groups. Synthetically useful transformations that do not fit easily into the first three chapters are considered next, with emphasis on functional group synthesis, ring expansion and contraction, and useful multistep transformations. The final chapter deals with miscellaneous reviews on topics ranging from cycloadditions to asymmetric catalysis, metalation, electrophilic substitutions, and pyrylium-mediated transformations of primary amino groups into other functional groups. This monograph will be of value to organic chemists, both specialist and nonspecialist in synthesis.

  • Acute Drug Abuse Emergencies

    A Treatment Manual
    • 1st Edition
    • Peter G. Bourne
    • English
    Acute Drug Abuse Emergencies: A Treatment Manual presents the most commonly encountered drug abuse emergencies. This book discusses how various drug-related conditions should be managed by practicing physicians and all those who are dealing with drug abusers. Organized into nine parts encompassing 28 chapters, this book begins with an overview of the various emergency drug reactions, including behavioral disturbances, organ malfunction, central nervous system depression, exacerbation of pre-existing illness, or combinations. This text then examines the profile of a typical heroin overdose victim. Other chapters consider severe poisoning due to nonbarbiturate sedative overdosage. This book discusses as well the types of adverse reactions to marihuana and the dangers of marihuana use. The final chapter deals with the ease of synthesis and the potency of arylcyclohexylamines as a mind-altering drug. This book is a valuable resource for toxicologists, emergency room physicians, and nurses. Readers who are dealing with drug abusers will also find this book extremely useful.

  • The Anatomy of Achievement Motivation

    • 1st Edition
    • Heinz Heckhausen
    • Brendan A. Maher
    • English
    The Anatomy of Achievement Motivation focuses on the study of individual differences in motivations, including the determinants of specific motives and methods of assessing motive strength. The book first offers information on content analysis and evaluative dispositions, as well as the theory of thematic apperception method, experimental method, and sociocultural frames of references and their change over historical time. The manuscript then highlights the important dimensions of experience and conflict. The publication takes a look at the general structure of goals and performance and valence and motive arousal, including psychic distance and discrepancy between a present and a future state. The book then examines goal setting and level of aspiration, performance period, and the origin and development of achievement motivation. The manuscript is a dependable reference for psychologists and readers interested in the facets of achievement motivation.

  • Steroid Dynamics

    Proceedings of the Symposium on the Dynamics of Steroid Hormones Held in Tokyo, May, 1965
    • 1st Edition
    • Gregory Pincus + 2 more
    • English
    Steroid Dynamics compiles papers presented at the Symposium on the Dynamics of Steroid Hormones held in Tokyo, in May 1965. This compilation discusses the effect of LH and ACTH on production and excretion of testosterone in vivo, estrogen receptors in target tissues, and influence of morphine on corticoid production. The binding of steroids to follicular fluid proteins, conjugation and excretion of aldosterone, and active cholesterol pool for corticodogenesis in the rat adrenal are also elaborated. This book likewise covers the dynamics of steroid hormone distribution in the body, biosynthesis of steroids in testicular tissue in vitro, and isotopic dilution methods for the estimation of rates of secretion of the steroid hormones. This publication is a good reference for endocrinologists, biochemists, and medical practitioners interested in steroid dynamics.

  • Advances in the Study of Aggression

    Volume 1
    • 1st Edition
    • Robert J. Blanchard + 1 more
    • English
    Advances in the Study of Aggression, Volume 1 aims to span some of the variety of aggression research, pinpointing areas in which phenomena or concepts that have arisen or been tested extensively with animal models are now being applied to human aggression. Chapter 1 presents an article on the relevance of animal aggression research to human aggression and discusses a brief sociobiological view of aggression and its immediate determinants over a number of mammalian species. A description of some features of human aggression and endeavor and its link to the animal model is also considered in this chapter. Chapter 2 is an article on the biological explanations of human aggression and the resulting therapies offered by such approaches, and Chapter 3 is an article on the development of stable aggressive reaction patterns in males. The next chapter is about the control of aggressive behavior by changes in attitudes, values, and the conditions of learning. Chapter 5 describes the coercive interactions of siblings and parents as well as those for siblings and identified problem children. Differences in sibling reactions between normal and distressed families together with the relationship of these differences to increased rates of coercive behaviors in distressed families are encompassed in this chapter. The text concludes by discussing advances in aggression research. Psychologists, psychiatrists, sociologists, anthropologists will find the book invaluable.

  • Recent Progress in Hormone Research

    Proceedings of the 1982 Laurentian Hormone Conference
    • 1st Edition
    • Roy O. Greep
    • English
    Recent Progress in Hormone Research, Volume 39 presents the proceedings of the 1982 Laurentian Hormone Conference. The book presents papers on the ovarian triad of the primate menstrual cycle; the measurement of local glucose utilization and its use in localization of functional activity in the central nervous system of animals and human; and the impact of estrogens on hypothalamic nerve cells. The text also describes the biosynthesis, processing, and secretion of parathormone and secretory protein-1; gastrointestinal peptides; chemical and biological characterization of corticotropin releasing factor; and the regulation of kidney functions by hormones. Papers on calcitonin, prolactin, and growth hormone gene expression; the expression of cloned growth hormone and metallothionein genes in heterologous cells; and the actions of insulin on glucose transport and cAMP phosphodiesterase in fat cells are also encompassed. The book further tackles papers on hormone-induced morphogenesis and growth; and Leydig cell structure and steroidogenic function. Endocrinologists, physiologists, biochemists, and scientists involved in hormone research will prove the text invaluable.

  • The Conservation of Orbital Symmetry

    • 1st Edition
    • R. B. Woodward + 1 more
    • English
    The Conservation of Orbital Symmetry examines the principle of conservation of orbital symmetry and its use. The central content of the principle was that reactions occur readily when there is congruence between orbital symmetry characteristics of reactants and products, and only with difficulty when that congruence does not obtain—or to put it more succinctly, orbital symmetry is conserved in concerted reaction. This principle is expected to endure, whatever the language in which it may be couched, or whatever greater precision may be developed in its application and extension. The book opens with a review of the elementary aspects of the molecular orbital theory of bonding. This is followed by separate chapters on correlation diagrams, the conservation of orbital symmetry, theory of electrocyclic reactions, theory of cycloadditions and cycloreversions, and theory of sigmatropic reactions. Subsequent chapters deal with group transfers and eliminations; secondary conformational effects in concerted cycloaddition reactions; and generalized selection rules for pericyclic reactions.

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