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Academic Press

  • Glucosinolates

    • 1st Edition
    • Volume 80
    • English
    Glucosinolates, the latest volume in the Advances in Botanical Research series, presents in-depth and up-to-date reviews on a wide range of topics in the plant sciences, with this edition focusing on glucosinolates. The individual chapters cover all aspects of glucosinolate research from biosynthesis, degradation, regulation, and ecology, to the mechanisms of their health benefits. The chapters are written by the world leaders of glucosinolate research.

  • Advances in Imaging and Electron Physics

    • 1st Edition
    • Volume 198
    • Peter W. Hawkes
    • English
    Advances in Imaging and Electron Physics merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. The series features extended articles on the physics of electron devices, especially semiconductor devices, particle optics at high and low energies, microlithography, image science, digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.

  • Big Mechanisms in Systems Biology

    Big Data Mining, Network Modeling, and Genome-Wide Data Identification
    • 1st Edition
    • Bor-Sen Chen + 1 more
    • English
    Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements. The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 50
    • English
    Advances in Physical Organic Chemistry series is the definitive resource for authoritative reviews of work in physical organic chemistry. It aims to provide a valuable source of information not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. Its hallmark is a quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

  • Spinal Muscular Atrophy

    Disease Mechanisms and Therapy
    • 1st Edition
    • Charlotte J Sumner + 2 more
    • English
    Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases.

  • Mesenchymal Stromal Cells as Tumor Stromal Modulators

    • 1st Edition
    • Marcela Bolontrade + 1 more
    • English
    Mesenchymal stromal/ stem cells (MSCs) represent a heterogeneous cell population with immunomodulating, tissue repairing, differentiating, migratory and angiogenic abilities, making them important tools for clinical and translational research. An understanding of the role of MSCs in modulating tumor growth provides a glimpse into their role in non-pathological tissue remodeling and potential regenerative tissue therapies. Mesenchymal Stromal Cells as Tumor Stromal Modulators is a comprehensive source for the understanding of the role of MSCs as ubiquitous connective tissue cell components, which may have both direct and indirect effects on the tumor microenvironment and potential for regenerative therapeutics for various diseases. Using cancer as a model disease, this book explores the transformative role MSCs play in the recruitment of disease cells, cell repair and immunological defenses.

  • Cardioskeletal Myopathies in Children and Young Adults

    • 1st Edition
    • John Lynn Jefferies + 3 more
    • English
    Cardioskeletal Myopathies in Children and Young Adults focuses on plaques that kill people in their 40’s-50’s and the way they start to form in young adulthood. The Annals of Family Medicine report that approximately half of young adults have at least one cardiovascular disease risk factor (Mar 2010), and an increase in cardiovascular mortality rates in young adults was substantiated in a study at Northwestern Medicine (Nov 2011). Given the increasing recognition of genetic triggers behind all types of cardiovascular disease, and the growing population of young adults with primary or acquired myocardial disease, the need has arisen for a reference that offers a comprehensive approach to the understanding of basic, translational, and clinical aspects of specific muscle diseases while making the link between young adult and adult health.

  • The Material Point Method

    A Continuum-Based Particle Method for Extreme Loading Cases
    • 1st Edition
    • Xiong Zhang + 2 more
    • English
    The Material Point Method: A Continuum-Based Particle Method for Extreme Loading Cases systematically introduces the theory, code design, and application of the material point method, covering subjects such as the spatial and temporal discretization of MPM, frequently-used strength models and equations of state of materials, contact algorithms in MPM, adaptive MPM, the hybrid/coupled material point finite element method, object-oriented programming of MPM, and the application of MPM in impact, explosion, and metal forming. Recent progresses are also stated in this monograph, including improvement of efficiency, memory storage, coupling/combination with the finite element method, the contact algorithm, and their application to problems.

  • Plant Hazard Analysis and Safety Instrumentation Systems

    • 1st Edition
    • Swapan Basu
    • English
    Plant Hazard Analysis and Safety Instrumentation Systems is the first book to combine coverage of these two integral aspects of running a chemical processing plant. It helps engineers from various disciplines learn how various analysis techniques, international standards, and instrumentation and controls provide layers of protection for basic process control systems, and how, as a result, overall system reliability, availability, dependability, and maintainability can be increased. This step-by-step guide takes readers through the development of safety instrumented systems, also including discussions on cost impact, basics of statistics, and reliability. Swapan Basu brings more than 35 years of industrial experience to this book, using practical examples to demonstrate concepts. Basu links between the SIS requirements and process hazard analysis in order to complete SIS lifecycle implementation and covers safety analysis and realization in control systems, with up-to-date descriptions of modern concepts, such as SIL, SIS, and Fault Tolerance to name a few. In addition, the book addresses security issues that are particularly important for the programmable systems in modern plants, and discusses, at length, hazardous atmospheres and their impact on electrical enclosures and the use of IS circuits.

  • Optimization of Manufacturing Systems Using the Internet of Things

    • 1st Edition
    • Yingfeng Zhang + 1 more
    • English
    Optimization of Manufacturing Systems Using the Internet of Things extends the IoT (Internet of Things) into the manufacturing field to develop an IoMT (Internet of Manufacturing Things) architecture with real-time traceability, visibility, and interoperability in production planning, execution, and control. This book is essential reading for anyone interested in the optimization and control of an intelligent manufacturing system. As modern manufacturing shop-floors can create bottlenecks in the capturing and collection of real-time field information, and because paper-based manual systems are time-consuming and prone to errors, this book helps readers understand how to alleviate these issues, assisting them in their decision-making on shop-floors.

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