Skip to main content
Elsevier

Academic Press

  • Milestones in Immunology

    Based on Collected Papers
    • 1st Edition
    • Domenico Ribatti
    • English
    Milestones in Immunology: Based on Collected Papers contains scientific milestones relating to the history of medicine over the past two centuries. The book highlights the contributions of pioneering scientists whose discoveries have paved the way for researchers working in the field of immunology. As the science of immunology grew from knowledge that survivors of common infectious diseases rarely contracted them again, the book uses this as a central thesis, helping readers understand how the adaptive immune system aids in defense against pathogens. In addition, the book covers special fields, such as immunohistochemistry... immunogenetics and immunopathology. For the past century, immunology has fascinated and inspired some of the greatest scientists of our time. Numerous Nobel Prizes have been awarded for fundamental discoveries in immunology, from Paul Ehrlich’ work on antibodies (1908) to the studies of Zinkernagel and Doherty (1986) elucidating mechanisms of cell-mediated immunity.

  • Cell Phone Location Evidence for Legal Professionals

    Understanding Cell Phone Location Evidence from the Warrant to the Courtroom
    • 1st Edition
    • Larry Daniel
    • English
    Cell Phone Location Evidence for Legal Professionals: Understanding Cell Phone Location Evidence from the Warrant to the Courtroom is a guide, in plain language, for digital forensics professionals, attorneys, law enforcement professionals and students interested in the sources, methods and evidence used to perform forensic data analysis of cell phones, call detail records, real time ping records and geo-location data obtained from cellular carriers and cell phones. Users will gain knowledge on how to identify evidence and how to properly address it for specific cases, including challenges to the methods of analysis and to the qualifications of persons who would testify about this evidence. This book is intended to provide digital forensics professionals, legal professionals and others with an interest in this field the information needed to understand what each type of evidence means, where it comes from, how it is analyzed and presented, and how it is used in various types of civil and criminal litigation. Relevant case law are included, or referred to, as appropriate throughout this book to give the reader an understanding of the legal history of this type of evidence and how it is being addressed by various state and federal courts.

  • Nitric Oxide (Donor/Induced) in Chemosensitization

    • 1st Edition
    • Volume 1
    • Benjamin Bonavida
    • English
    Nitric Oxide as a Chemosensitizing Agent, Volume One is the first book to describe several reviews by authoritative scientists and clinicians on novel findings in the reversal of drug resistant cancers by the combination treatment of Nitric Oxide and sub toxic concentrations of chemotherapeutic drugs that have been reported in both in vitro, in vivo and preclinical models. The book describes the various underlying chemical, molecular and genetic mechanisms by which NO and NO reactive species mediate the anti-cancer activity, thus reducing the threshold of drug resistance and enabling chemo therapeutic drugs to induce their cytotoxic activity and reversal of resistance. This book exposes scientists and clinicians to this highly beneficial topic for research investigations and pharmaceutical companies to new avenues for R&D. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use Nitric Oxide as a sensitizing agent for chemotherapy.

  • Topology Design Methods for Structural Optimization

    • 1st Edition
    • Osvaldo M. Querin + 4 more
    • English
    Topology Design Methods for Structural Optimization provides engineers with a basic set of design tools for the development of 2D and 3D structures subjected to single and multi-load cases and experiencing linear elastic conditions. Written by an expert team who has collaborated over the past decade to develop the methods presented, the book discusses essential theories with clear guidelines on how to use them. Case studies and worked industry examples are included throughout to illustrate practical applications of topology design tools to achieve innovative structural solutions. The text is intended for professionals who are interested in using the tools provided, but does not require in-depth theoretical knowledge. It is ideal for researchers who want to expand the methods presented to new applications, and includes a companion website with related tools to assist in further study.

  • RNA Modification

    • 1st Edition
    • Volume 41
    • English
    RNA Modification, Volume 41 examines the powerful ability to regulate the function of RNA molecules or modify the message transmitted by RNA molecules. Chapters in this newly released volume include The Importance of Being Modified: Modifications Shape RNA Function through Chemistry, Structure and Dynamics, The evolution of multi-substrate specificity by RNA modification enzymes, TrmD: a methyl transferase for tRNA methylation with m1G37, Structures and activities of the Elongator complex and its co-factors, RNA pseudouridylation: Mechanism and Function, The activity of 5’3' exonucleases on hypo modified tRNA substrates and other structured RNAs, and the Synthesis, heterogeneity and function of post-transcriptional nucleotide modifications in eukaryotic ribosomal RNAs. This field has recently seen a very rapid progress in the understanding of the mechanism and enzymes involved in RNA modification. This volume presents some of the most recent advances in the identification and function of enzymes involved in modifying RNA molecules.

  • Kidney Transplantation, Bioengineering, and Regeneration

    Kidney Transplantation in the Regenerative Medicine Era
    • 1st Edition
    • Giuseppe Orlando + 2 more
    • English
    Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney.

  • Encapsulated Catalysts

    • 1st Edition
    • Samahe Sadjadi
    • English
    Encapsulated Catalysts provides valuable information for chemists, chemical engineers, and materials scientists in this promising area. The book describes many kinds of encapsulated catalysts and their applications in chemistry, including organic, inorganic, hybrid, and biological systems. Unlike other works, which discuss traditional supports, this useful resource uniquely focuses on extremely important topics, such as the encapsulation effects on reactivity and selectivity, the difficulty of their separation from reaction mixture, and/or their sensitivity to reaction conditions, and the limit of their industrial applications. In addition, the book covers the immobilization of homogenous catalysts on inorganic or organic supports and how it enables the separation of homogenous catalysts, as well as the protection or reuse of catalysts.

  • Toxicology: What Everyone Should Know

    • 1st Edition
    • Aalt Bast + 1 more
    • English
    Toxicology: What Everyone Should Know is an essential reference for anyone looking for an entry into this fascinating field of study. This innovative book describes important discoveries in toxicology through the ages, explores their historical and sociological impacts, and shows how they still influence recent, state-of-the-art developments. In addition, the book shows how these developments are extrapolated into public and political perceptions on risks and the regulatory consequences, emphasizing environmental issues, such as manmade and natural chemicals, their interaction and impact, nutrition, and drugs. Users will find a cutting-edge approach to nutritional and combinatorial toxicology, risk evaluation modeling and the benefits of chemicals exposure (nutrition versus man-made chemicals), environmental health, and legislative frameworks to control the public’s chemical exposure. This is an essential reference for those looking for an introduction to toxicology, its past, and exciting future.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 67
    • English
    Advances in Organometallic Chemistry, Volume 67 contains authoritative review articles of worldwide known researchers on the field of organometallic chemistry, covering topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. Updates in this new volume include chapters on Group 6 Metal Fischer Carbene Complexes: Versatile Synthetic Building Blocks, Recent Advances in Transition-Metal-Cat... Cross-Coupling Reactions With Tosylhydrazones,Oxid... Functionalization of Late Transition Metal-Carbon Bond, and Biaryl Synthesis via C–H Bond Activation: Strategies and Methods. This book will benefit a wide range of researchers involved in organometallic chemistry, including those working on synthetic protocols, mechanistic studies and practical applications.

  • A Comprehensive and Practical Guide to Clinical Trials

    • 1st Edition
    • Delva Shamley + 1 more
    • English
    A Comprehensive and Practical Guide to Clinical Trials provides an overview of the entire process of clinical research in one thorough and easy-to-read handbook that offers those involved in clinical research a clear understanding of how the components of a study are related. It focuses on the practical aspects of the preparation and execution of a clinical trial and offers tools and resources to help the entire team understand how their responsibilities tie together with the tasks and duties of other members. This allows for better planning and prioritization, and can lead to more effective and successful clinical trials. With practical examples, checklists and forms, this book is a useful guide for planning and conducting clinical trials from beginning to end.

Browse by Publisher