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Academic Press

    • Nanotechnology Based Approaches for Tuberculosis Treatment

      • 1st Edition
      • June 10, 2020
      • Prashant Kesharwani
      • English
      • Paperback
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      • eBook
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      Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis.
    • Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles

      • 1st Edition
      • June 10, 2020
      • Peter Gill + 4 more
      • English
      • Paperback
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      Over the past twenty years, there’s been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting ‘probabilistic genotyping’ to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range of technologies are used to interpret DNA profiles and the software approaches advocated are commonly used throughout the world. Forensic Practitioner’s Guide to the Interpretation of Complex DNA Profiles places the main concepts of DNA profiling into context and fills a niche that is unoccupied in current literature. The book begins with an introduction to basic forensic genetics, covering a brief historical description of the development and harmonization of STR markers and national DNA databases. The laws of statistics are described, along with the likelihood ratio based on Hardy-Weinberg equilibrium and alternative models considering sub-structuring and relatedness. The historical development of low template mixture analysis, theory and practice, is also described, so the reader has a full understanding of rationale and progression. Evaluation of evidence and statement writing is described in detail, along with common pitfalls and their avoidance. The authors have been at the forefront of the revolution, having made substantial contributions to theory and practice over the past two decades. All methods described are open-source and freely available, supported by sets of test-data and links to web-sites with further information. This book is written primarily for the biologist with little or no statistical training. However, sufficient information will also be provided for the experienced statistician. Consequently, the book appeals to a diverse audience
    • Jaguars of the Northern Pantanal

      • 1st Edition
      • June 10, 2020
      • Paul Brooke + 1 more
      • English
      • Paperback
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      Jaguars of the Northern Pantanal: Panthera Onca at the Meeting of the Waters details the lives and behaviors of this subpopulation of jaguars through one-of-a-kind photographs from 26 international photographers, as well as illustrations, maps, waypoints, scientific insights, field journal excerpts and personal narratives. The book seeks to understand how locals can coexist with these cats while benefitting financially through ecotourism. Users will find this book to be a conceptual model to apply to other subpopulations in order to save jaguars throughout North and South America. It is an ideal resource for researchers and practitioners in wildlife conservation, naturalism ecotourism and biologists.
    • Animal Biotechnology

      • 2nd Edition
      • June 9, 2020
      • Ashish S. Verma + 1 more
      • English
      • Hardback
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      • eBook
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      Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more.
    • Transdermal Drug Delivery

      • 1st Edition
      • June 9, 2020
      • Kevin Ita
      • English
      • Paperback
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      • eBook
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      Transdermal Drug Delivery: Concepts and Application provides comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings. Ironically, only about 40 transdermal products with distinct active pharmaceutical ingredients are in the market indicating that more needs to be done to chronicle recent advances made in this area and to elucidate the mechanisms involved. This book will be helpful to researchers in the pharmaceutical and biotechnological industries as well as academics and graduate students working in the field of transdermal drug delivery and professionals working in the field of regulatory affairs focusing on topical and transdermal drug delivery systems. Researchers in the cosmetic and cosmeceutical industries, as well as those in chemical and biological engineering, will also find this book useful.
    • Human-Machine Shared Contexts

      • 1st Edition
      • June 9, 2020
      • William Lawless + 2 more
      • English
      • Paperback
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      • eBook
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      Human-Machine Shared Contexts considers the foundations, metrics, and applications of human-machine systems. Editors and authors debate whether machines, humans, and systems should speak only to each other, only to humans, or to both and how. The book establishes the meaning and operation of “shared contexts” between humans and machines; it also explores how human-machine systems affect targeted audiences (researchers, machines, robots, users) and society, as well as future ecosystems composed of humans and machines. This book explores how user interventions may improve the context for autonomous machines operating in unfamiliar environments or when experiencing unanticipated events; how autonomous machines can be taught to explain contexts by reasoning, inferences, or causality, and decisions to humans relying on intuition; and for mutual context, how these machines may interdependently affect human awareness, teams and society, and how these "machines" may be affected in turn. In short, can context be mutually constructed and shared between machines and humans? The editors are interested in whether shared context follows when machines begin to think, or, like humans, develop subjective states that allow them to monitor and report on their interpretations of reality, forcing scientists to rethink the general model of human social behavior. If dependence on machine learning continues or grows, the public will also be interested in what happens to context shared by users, teams of humans and machines, or society when these machines malfunction. As scientists and engineers "think through this change in human terms," the ultimate goal is for AI to advance the performance of autonomous machines and teams of humans and machines for the betterment of society wherever these machines interact with humans or other machines. This book will be essential reading for professional, industrial, and military computer scientists and engineers; machine learning (ML) and artificial intelligence (AI) scientists and engineers, especially those engaged in research on autonomy, computational context, and human-machine shared contexts; advanced robotics scientists and engineers; scientists working with or interested in data issues for autonomous systems such as with the use of scarce data for training and operations with and without user interventions; social psychologists, scientists and physical research scientists pursuing models of shared context; modelers of the internet of things (IOT); systems of systems scientists and engineers and economists; scientists and engineers working with agent-based models (ABMs); policy specialists concerned with the impact of AI and ML on society and civilization; network scientists and engineers; applied mathematicians (e.g., holon theory, information theory); computational linguists; and blockchain scientists and engineers.
    • Goodman's Medical Cell Biology

      • 4th Edition
      • June 9, 2020
      • Steven R. Goodman
      • English
      • Paperback
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      Goodman’s Medical Cell Biology, Fourth Edition, has been student tested and approved for decades. This updated edition of this essential textbook provides a concise focus on eukaryotic cell biology (with a discussion of the microbiome) as it relates to human and animal disease. This is accomplished by explaining general cell biology principles in the context of organ systems and disease.This new edition is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study.
    • Phenotypic Switching

      • 1st Edition
      • June 8, 2020
      • Herbert Levine + 3 more
      • English
      • Paperback
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      • eBook
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      Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications in cancer therapy, regenerative medicine and stem cell therapy, among other treatments. Chapters discuss fundamental mechanisms of phenotypic switching, including transition states, cell fate decisions, epigenetic factors, stochasticity, protein-based inheritance, specific areas of human development and disease relevance, phenotypic plasticity in melanoma, prostate cancer, breast cancer, non-genetic heterogeneity in cancer, hepatitis C, and more. This book is essential for active researchers, basic and translational scientists, clinicians, postgraduates and students in genetics, human genomics, pathology, bioinformatics, developmental biology, evolutionary biology and adaptive opportunities in yeast.
    • Contemporary Practice in Clinical Chemistry

      • 4th Edition
      • June 8, 2020
      • William Clarke + 1 more
      • English
      • Paperback
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      Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry.
    • Segregation in Vibrated Granular Systems

      • 1st Edition
      • June 5, 2020
      • Anthony D. Rosato + 1 more
      • English
      • Paperback
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      Segregation in Vibrated Granular Systems explains the individual mechanisms that influence the segregation of granular media under vibration, along with their interactions. Drawing on research from a wide range of academic disciplines, the book focuses on vibrated granular systems that are used in industry, providing a guide that will solve practical problems and help researchers. The applications of vibration-based segregation in industries, including pharmaceuticals, mining, food and chemical processing are all investigated with appropriate examples. In addition, relevant theory behind the behavior of granular media and segregation processes is explained, along with investigations of the technologies and techniques used.