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Elsevier

Academic Press

  • DNA Damage and Chromosomal Instability

    • 1st Edition
    • Volume 182
    • English
    DNA Damage and Chromosomal Instability, Volume 182 in the Methods in Cell Biology series, presents interesting chapters on a variety of timely topics, including Induction of chromosome-specific micronuclei and chromothripsis by centromere inactivation, Generation of aneuploid cells and assessment of their ability to survive in presence of chemotherapeutic agents, Genetic reporters to detect and quantify homologous recombination in yeast, Mapping histone variant genomic distribution: exploiting SNAP- Tag labelling to follow the dynamics of incorporation of H3 variants, Enrichment of DNA replication intermediates by EdU pull down, Nascent DNA sequencing and its diverse applications in genome integrity research, and much more. Additional chapters cover Enrichment of DNA replication intermediates by EdU pull down, DNA curtains for studying phase separation mechanisms of DNA-organizing proteins, Visualizing the Dynamics of DNA Replication and Repair at the Single-Molecule Molecule Level, Cloning and Expansion of Repetitive DNA Sequences, Using an ImageJ-based script to detect replication stress and associated cell cycle exit from G2 phase by fluorescence microscopy Arne Lindqvist

  • A Comprehensive Guide to Toxicology in Nonclinical Drug Development

    • 3rd Edition
    • Ali S. Faqi
    • English
    **Selected for 2026 Doody's Core Titles in Toxicology**A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings.

  • Dysphagia

    A Clinical Guide
    • 1st Edition
    • Michael B. Ujiki + 1 more
    • English
    Dysphagia: A Clinical Guide will help practitioners and surgeons learn and understand how best to diagnose and treat dysphagia. It provides a complete picture of dysphagia through the experiences of leaders who cover the latest techniques and evidence-based outcomes in the field. Coverage includes recent advances in the diagnosis and treatment of the disease processes that cause dysphagia, gastric problems, and surgical intervention. The book includes the latest research and perspectives from both gastroenterologists and surgeons to enable clinicians to stay up-to-date on the most current and effective management strategies. Each chapter provides summary statements and recommendations based on recent literature.Recent discoveries regarding the diagnosis and management of dysphagia are exemplified by illustrations of both diagnostic methods and descriptions of interventional techniques. This an important reference for general surgeons, general practitioners, and ENT surgeons while also bringing new data dedicated specifically to gastroenterologists and foregut surgeons.

  • Renewable Energy Systems

    A Smart Energy Systems Approach to the Choice and Modeling of Fully Decarbonized Societies
    • 3rd Edition
    • Henrik Lund
    • English
    Renewable Energy Systems: A Smart Energy Systems Approach to the Choice and Modeling of Fully Decarbonized Societies Third Edition includes updates from globally recognized renewable energy researcher and professor, Henrik Lund, who sets forth a comprehensive methodology for comparing different energy systems’ abilities to integrate fluctuating and intermittent renewable energy sources to achieve a fully decarbonized society. The book presents an energy system analysis methodology, providing the results of more than 15 comprehensive studies, examining the large-scale integration of renewable energy and presenting concrete design examples derived from a dozen renewable energy systems around the globe.The book also undertakes the socio-political realities governing the implementation of renewable energy systems by introducing a theoretical framework approach aimed at understanding how major technological changes, such as renewable energy, can be implemented at both the national and international levels. This is a valuable resource for researchers, scientists, engineers, project managers, policymakers, consultants, and graduate students with an interest in planning, modelling, and implementation of renewable energy systems.

  • Translational Approaches to Unravelling Non-Motor Symptoms of Parkinson’s disease

    • 1st Edition
    • Volume 174
    • English
    Translational Approaches to Non-Motor Symptoms of Neurodegenerative Diseases, Volume 173 in the International Review on Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as A general clinical overview of the non-motor symptoms, Stress/fatigue/cogni... decline Sleep/autonomic failure, A general clinical overview of the non-motor symptoms – psychiatric symptoms, Psychosis, Cognitive Decline, Non-clinical Aspect of non-motor symptoms: Animal Models, Assessment and treatment of cognitive decline in rodent and primate models, Pain in PD models, Affective disorders in PD models, Sleep and circadian dysregulation and EEG disruption in rodent models, and much more.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 142
    • English
    Advances in Heterocyclic Chemistry, Volume 142, the latest release in this definitive series, combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Chapters in this new release include Recent advances in the Synthesis of Benzo[b]furans, Recent Advances in the Synthesis of 6-Membered Heterocycles via Domino and Multicomponent Reactions (from 2017-2022), Multi-component synthesis of isatin based bioactive heterocycles, Recent advances in the chemistry of pyrazolo[1,5-a]pyrim... The Literature of Heterocyclic Chemistry, Part XXI, 2021, and much more.Additional sections present the latest Advances in applications of dihydropyridines in organic chemistry and Strategies for the annulation of five-membered sulfur-nitrogen rings to benzene and heterocycles.

  • Advances in Agronomy

    • 1st Edition
    • Volume 184
    • English
    Advances in Agronomy, Volume 184, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors, with this new release including new chapters on The Role of Artificial Intelligence in Crop Improvement, Dealing with the Impact of Climate Change-Induced Drought on the Management of Soil, Challenges and Emerging Opportunities of Weed Management in Organic Agriculture, The Broadbalk Wheat Experiment, Rothamsted, UK: Crop Yields and Soil Changes During the Last 50 Years.

  • Internet of Things: Architectures for Enhanced Living Environments

    • 1st Edition
    • Volume 133
    • Goncalo Marques
    • English
    Internet of Things: Architectures for Enhanced Living Environments, Volume 133 presents interesting chapters on a variety of timely topics, including Explainable Artificial Intelligence for Enhanced Living Environments: A Study on User Perspective, Human behavioral anomaly pattern mining within an IoT environment: an exploratory study, Indoor Activity Localization Technologies for Assisted Living: Opportunities, Challenges, and Future Directions, Smart Indoor Air Quality Monitoring for Enhanced Living Environments and Ambient Assisted Living, Usability evaluation for the IoT use in Enhanced Living Environments, Roadmap to the elderly enhanced living and care environments: applications and challenges on the Internet of Things domain, and much more.

  • The Neuroscience of Bach’s Music

    Perception, Action, and Cognition Effects on the Brain
    • 1st Edition
    • Eric Altschuler
    • English
    The Neuroscience of Bach’s Music: Perception, Action, and Cognition Effects on the Brain is a comprehensive study of Johann Sebastian Bach’s music through the lens of neuroscience, examining neuroscience using Bach’s music as a tool. This book synthesizes cognitive neuroscience, music theory, and musicology to provide insights into human cognition and perception. It also explores how a neuroscience perspective can improve listening and performing experiences for Bach’s music. Written by a physician-neuroscien... recognized for scholarly articles on Bach’s music, this book uses specific examples to explore neuroscience across Bach’s compositions.The book is structured to discuss the brain’s action, perception, and cognition as connected to specific Bach concertos, tones, notes, and performances. Two guest contributors provide insight into exact mathematical, or topologic, and music theoretic aspects of Bach’s music with implications for cognitive neuroscience.

  • Modeling and Analysis of Longitudinal Data

    • 1st Edition
    • Volume 50
    • English
    Longitudinal Data Analysis, Volume 50 in the Handbook of Statistics series covers how data consists of a series of repeated observations of the same subjects over an extended time frame and is thus useful for measuring change. Such studies and the data arise in a variety of fields, such as health sciences, genomic studies, experimental physics, sociology, sports and student enrollment in universities. For example, in health studies, intra-subject correlation of responses must be accounted for, covariates vary with time, and bias can arise if patients drop out of the study.

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