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Academic Press

  • Therapeutic Monoclonal Antibodies: From Lot Release to Stability Testing

    • 1st Edition
    • Harleen Kaur
    • English
    Therapeutic Monoclonal Antibodies: From Lot Release to Stability Testing is a highly topical resource on a subject of interest for scientists and researchers working on monoclonal antibodies' characterization, release testing, stability testing and similarity assessments of monoclonal antibodies in the biopharmaceutical industry. Monoclonal antibodies (mAbs) are large, extremely complex and dynamic biomolecules, so it can be challenging to develop well-characterized therapeutic antibodies that meet regulatory expectations that are also in-line with commercialized standards for different drug markets.Lot release testing and understanding the stability of the mAb over a period of time, and in different environmental conditions, is an indispensable aspect of mAb physicochemical characterization. This book covers the process, including extensive analysis that starts with quantifying the purity attribute to glycan profiling and identifying the mAb primary structure. The book has a primary purpose of focusing on both Lot release testing and stability testing of monoclonal antibodies (subjects not covered in any great detail in other books).

  • Bioactive Materials for Soft Tissue Regeneration

    • 1st Edition
    • Jiang Chang + 2 more
    • English
    Bioactive Materials for Soft Tissue Regeneration covers human tissue and its classification as hard tissue such as bone and soft tissue like skin, muscle, tendon, blood vessel, nerve etc., and including organs such as heart, liver, lung. Regenerative medicine deals with both hard tissue and soft tissue regeneration and is one of the most important part of the modern medicine with significant clinical needs including general surgery, plastic surgery, burn and wound healing, cardiovascular disease treatments. Based on the authors’ previous research and review of the international advances in hard tissue regeneration, this book focuses on the hard tissue regeneration using bioactive materials.Sections cover biomaterials for entire human tissue regeneration, which is key important for research and development in the field of biomedical engineering and the medical device industry. Readers will find this to be a comprehensive review of the most updated advances of the research in bioactive materials for soft tissue repair and regeneration, along with perspectives for future directions of research and development in this field.

  • Defense-Related Proteins in Plants

    • 1st Edition
    • Santosh Kumar Upadhyay
    • English
    Defense-related Proteins in Plants presents detailed information on the identification, characterization, mechanism of action, and application in crop improvement programs of these mechanisms in a single, cohesive volume. It includes foundational information to enable the understanding of these proteins and their applications in crop improvement programs.Defense-rel... proteins have drawn the attention of various plant and agricultural scientists and industries because they provide generalized direct stress tolerance in crop plants. These proteins, including lectins, chitinases, thaumatin, and osmotin among others, have been used for the development of transgenic plants to provide protection against various abiotic and biotic stresses. While there is a breadth of research and application information available, it has not previously been compiled into a single volume for the ease of comparison and translational work. This book is a complete guide to defense-related proteins in plants for various categories of readers. Also, it will inspire future research into the unexplored areas of the molecular aspects of these proteins to understand their role and action mechanism in plants and living organisms as a whole. Additionally agricultural scientists and industry professionals will find the application part of this book helpful in future crop design strategies.

  • Advances in Motivation Science

    • 1st Edition
    • Volume 11
    • English
    Advances in Motivation Science, Volume Eleven, the latest release in the Motivation Science series, contains interesting articles that cover topics such as An Ecology of Meaning: An Integrative Framework for Understanding Human Motivations, Beer AMS Quest for Self Knowledge, Boundary conditions of the rational model Finding the limits of rationality, Growth goals: A review of the construct Predictors, Consequences, and Intervention, Pragmatic Prospection Theory, Research, and Practice, and The Quest for Self-Knowledge What Do We Want to Know (and not Know) About Ourselves.

  • Advances in Heat Transfer

    • 1st Edition
    • Volume 57
    • English
    Advances in Heat Transfer, Volume 57 presents the latest in a serial that highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 66
    • English
    Advances in Insect Physiology, Volume 66 in the series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Cockroach Biology, Apocrine Secretion from Salivary Glands, and Female Insect Reproduction.

  • Advances in Experimental Social Psychology

    • 1st Edition
    • Volume 70
    • English
    The Advances in Experimental Social Psychology series is the premier outlet for reviews of mature, high-impact research programs in social psychology. Contributions to the series provide defining pieces of established research programs, reviewing and integrating thematically related findings by individual scholars or research groups. Topics discussed in Volume 70 include narrative transportation; group life and personal agency; victimhood and morality; goal pursuit and risk behavior; and identity fusion

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 84
    • English
    Advances in Microbial Physiology, Volume 84 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include Mycobacterial Efflux systems, New insights in bacterial organophosphorus cycling: from human pathogens to environmental bacteria, Link between gut sulfidogenic bacteria and disease, The Formate-H2 Axis and its Importance for Microbial Physiology, Physiology of diazotrophs, Antibiotic efficacy, and Microbial metabolites as modulators of host physiology.

  • Atlas of Hematopathology with 100 Case Studies

    • 1st Edition
    • Faramarz Naeim + 2 more
    • English
    Atlas of Hematopathology with 100 Case Studies is a practical guide useful for pathologists and hematologists, residents and fellows, laboratory directors, researchers, and students in the field of hematology, cytogenetic, and molecular pathology. The book offers important information to practicing physicians and those in pathology and hematology training to improve their diagnostic skills. It covers the most important aspects of hematopathology, including classifications, clinical symptoms, hematopathologic features, diagnostic criteria, differential diagnosis, and the use and importance of ancillary testing, such as immunohistochemistry... flow cytometry, and cytogenetics.

  • Federated Learning for Digital Healthcare Systems

    • 1st Edition
    • Agbotiname Lucky Imoize + 2 more
    • English
    Federated Learning for Digital Healthcare Systems critically examines the key factors that contribute to the problem of applying machine learning in healthcare systems and investigates how federated learning can be employed to address the problem. The book discusses, examines, and compares the applications of federated learning solutions in emerging digital healthcare systems, providing a critical look in terms of the required resources, computational complexity, and system performance.In the first section, chapters examine how to address critical security and privacy concerns and how to revamp existing machine learning models. In subsequent chapters, the book's authors review recent advances to tackle emerging efficient and lightweight algorithms and protocols to reduce computational overheads and communication costs in wireless healthcare systems. Consideration is also given to government and economic regulations as well as legal considerations when federated learning is applied to digital healthcare systems.

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