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Elsevier

Books in Social sciences and humanities

  • Handbook of Toxic Fungal Metabolites

    • 1st Edition
    • Bozzano G Luisa
    • English
    Handbook of Toxic Fungal Metabolites presents UV, IR, 1H NMR, 13C NMR, and mass spectra for identification of known mycotoxins or related metabolites by both chemists and researchers. The handbook is oriented primarily toward fungal metabolites that elicit a toxic response in vertebrate animals. It also contains metabolites that show little or no known acute toxicity. The handbook is divided into 21 sections. Mycotoxin and fungal metabolite members are considered into each section based on their chemical relationships, except for the last four groups, Aspergillus, Penicillium, Fusarium, and miscellaneous toxins. The final section focuses on miscellaneous toxins that could not be classified under the considered categories, namely slaframine, diplodiatoxin, and roseotoxin B. This handbook is of great value to mycotoxicologists, and food and feed researchers.

  • Understanding Immunology

    • 1st Edition
    • Alastair J. Cunningham
    • English
    Understanding Immunology deals with immunology and its unifying principles, based on the view that the immune system has evolved to combat infectious disease. This book describes the phylogenetic emergence of the immune system; immune reactions in invertebrates and vertebrates; antibody-antigen reactions and the induction of the antibody response; the development of the immune repertoire and self-tolerance; and memory and tolerance in T-cells. This text is organized into 15 chapters and begins with an overview of the immune system, paying particular attention to its basic requirements and properties. This book then discusses antibodies and antigens; the molecular biology of antibody formation; and the role of lymphocytes, lymphoid tissue, and antibody forming cells in the immune response. The following chapters focus on immunocompetent cells and the mechanisms of cell cooperation in the induction of the antibody response, properties of the cells responsible for memory, and the genetic basis of antibody diversity. The reader is also introduced to allelic exclusion and the ontogeny of the immune repertoire; differentiation of T-cells; and cancer and transplantation immunology. The remaining chapters explore aberrations of the immune system and immunity to infectious disease. A comparison of the strategies of vertebrates and invertebrates in adapting to unexpected changes in the environment concludes the book. This book will prove useful as an introduction to immunology to those with some background in biology, particularly, undergraduate or graduate students as well as established researchers in other fields.

  • Bacterial Vaccines

    • 1st Edition
    • Rene Germanier
    • English
    Bacterial Vaccines provides information dealing with vaccination of man against bacterial diseases. This book emphasizes the description, composition, production, and control of the vaccines, as well as vaccine benefits and drawbacks. Organized into 14 chapters, this book contains a description of the etiological agent, particularly with respect to its antigenic composition, and also of the pathogenesis of the disease and the immune mechanisms acting against it. The chapters are separated according to the disease they describe, which include diphtheria, tetanus, pertussis, cholera, typhoid fever, shigellosis, Escherichia coli infections, meningococcal meningitis, pneumococcal infections, Haemophilus influenzae type b infections, Pseudomonas aeruginosa infections, gonorrhea, tuberculosis, and leprosy. This book will provide the reader with a comprehensive survey of vaccination of man against bacterial diseases. It is intended for those involved in vaccine development, production, and control.

  • Handbook of Human Vibration

    • 1st Edition
    • M. J. Griffin
    • English
    Today the human body is exposed to vibration not only while traveling but also during leisure and domestic activities and in many occupations. This volume summarizes the current understanding of the many human responses to vibration.Divided into two parts, this book deals with whole-body vibrations and hand-transmitted vibration. In each part the experimental data and appropriate models are presented in detail so that readers can address practical problems. An extensive guide to national and international standards is provided, and a large multidisciplinary glossary of terms assists in understanding the relevant technical and medical jargon.This comprehensive reference volume is accessible to all those interested in human vibration: medical doctors, engineers, lawyers, scientists, and health and safety officials and administrators.

  • Applied Virology

    • 1st Edition
    • Bozzano G Luisa
    • English
    Applied Virology covers the practical applications of the developments in basic virology, not only to virology but to other disciplines as well, and demonstrates the impact of virus diseases on the environment, economy, and the health of man, animals, and plants. The book discusses topics on new virus vaccine technology and chemotherapy; the status of vaccination against viral diseases; and the epidemiology and diagnosis of viral diseases. The text provides information on the strategy used to produce virus vaccines; on antiviral chemical compounds; on simple, rapid, and specific diagnostic techniques; and on epidemiology in relation to the prevention and control of virus diseases. Noninfectious, synthetized peptides used as safe virus vaccines are reviewed with special attention to their immunogenicity, multispecificity, and usefulness in case of epidemics. Virologists will find the book useful.

  • The Togaviruses

    Biology, Structure, Replication
    • 1st Edition
    • Walter R Schlesinge
    • English
    The Togaviruses: Biology, Structure, Replication deals with the biology, structure, and replication of rotaviruses. This book covers topics such as the biochemistry of rotaviruses and the biological and medical challenges they pose. It also gives an account of their mechanisms of replication that might lead to perceptions of the capacity to solve biological and epidemiological problems through the concepts and technology of molecular biology. This text is comprised of 21 chapters that explore clinical details, routine procedures for diagnostic virus isolation and identification and for serological tests; immunological host responses; the role of interferons; antiviral chemotherapy; and vaccine development. The discussion begins with a historical overview of arboviruses, followed by a description of all the viruses that belong to Togaviridae. These include alpha- and flaviviruses, rubiviruses, pestiviruses, and other ""non-arbo"" togaviruses. The next chapters focus on the arthropod-vertebrate... transmission cycle and its experimental equivalents, along with the viruses' structure, composition, and replication. This book concludes with a summary of physicochemical, morphological, and clinical data on non-arbo togaviruses. This reference material will be of interest to physicians, veterinarians, ecologists, entomologists, epidemiologists, cell biologists, immunologists, virologists, physical chemists, biochemists, molecular biologists, and geneticists.

  • Handbook of Proteolytic Enzymes, Volume 1

    • 2nd Edition
    • Alan J. Barrett + 2 more
    • English
    Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.

  • The Autoimmune Diseases

    • 1st Edition
    • Bozzano G Luisa
    • English
    The Autoimmune Diseases is composed of 25 chapters dealing with different aspects of some specific autoimmune diseases. The book begins with the elucidation of the genetic predisposition to autoimmune diseases. Subsequent chapters explore numerous kinds of autoimmune diseases. Other chapters describe the antireceptor antibodies and the sensitivity and specificity of autoantibody testing. This book is designed to provide a deeper understanding of this increasingly important field of medical science for physicians and investigators involved in the diagnosis, treatment, or research of autoimmune diseases.

  • Gene Activity in Early Development

    • 3rd Edition
    • Bozzano G Luisa
    • English
    The new third edition of Gene Activity in Early Development reflects the ten years of technological progress since the last edition. Providing a unique blend of classical and molecular knowledge, it discusses all major embryonic systems from both a comparative and mechanistic point of view. In deriving overall interpretations of developmental phenomena, it brings into play all the disparate forms of evidence, including genetic, molecular, and cytological.**This book is written for any serious student or scholar entering the field, whether his or her background is in genetics, molecular biology, or embryology.

  • Handbook of Perception Volume 6A

    • 1st Edition
    • Edward C. Carterette
    • English
    Handbook of Perception, Volume VIA Tasting and Smelling focuses on the psychophysics of tasting and smelling and covers topics ranging from food technology and the neurophysiology of taste to the chemistry of odor, the neural code, the olfactory process, and chemical signals in the environment. This volume is organized into five sections encompassing 10 chapters and begins with a historical overview of taste research, followed by a discussion on the biophysics and chemistry of taste and its phylogenetic basis in vertebrates. The focus then shifts to the nature of taste qualities, the psychophysical methods of studying them, and the influence on taste sensation of factors such as intensity, duration and area of stimulation. The important phenomenon of adaptation is well covered, with attention to the role of water. The book methodically introduces the reader to the pleasantness or unpleasantness of a food, the physicochemical basis of olfaction, information processing in the olfactory nerve pathway, and the relationship between molecular structure and odor. A chapter on the extraneous stimulation caused by industrial processes, the psychophysical foundation for applications of olfactory research, and real and potential applications in the realm of odor abatement concludes the volume. This book will serve as a basic source and reference work for psychologists and natural scientists, as well as for those who are interested in human perception.

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