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Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

BooksJournals

    • Retention and Selectivity in Liquid Chromatography

      • 1st Edition
      • Volume 57
      • January 13, 1995
      • R.M. Smith
      • English
      • Hardback
        9 7 8 0 4 4 4 8 1 5 3 9 2
      • Paperback
        9 7 8 0 4 4 4 5 4 8 1 9 1
      • eBook
        9 7 8 0 0 8 0 8 5 8 6 5 4
      This book brings together a number of studies which examine the ways in which the retention and selectivity of separations in high-performance liquid chromatography are dependent on the chemical structure of the analytes and the properties of the stationary and mobile phases. Although previous authors have described the optimisation of separations by alteration of the mobile phase, little emphasis has previously been reported of the influence of the structure and properties of the analyte.The initial chapters describe methods based on retention index group increments and log P increments for the prediction of the retention of analytes and the ways in which these factors are influenced by mobile phases and intramolecular interactions. The values of a wide range of group increments in different eluents are tabulated.Different scales of retention indices in liquid chromatography are described for the comparison of separations, the identification of analytes and the comparison of stationary phases. Applications of these methods in the pharmaceutical, toxicology, forensic, metabolism, environmental, food and other fields are reviewed. The effects of different mobile phases on the selectivity of the retention indices are reported. A compilation of sources of reported retention index values are given.Methods for the comparison of stationary phases based on the interactions of different analytes are covered, including lipophilic and polar indices, shape selectivity comparisons, their application to novel stationary phases, and chemometric methods for column comparisons.

    • QSAR and Drug Design: New Developments and Applications

      • 1st Edition
      • Volume 23
      • November 20, 1995
      • H. Timmerman
      • T. Fujita
      • English
      • Paperback
        9 7 8 0 4 4 4 5 5 5 7 2 4
      • eBook
        9 7 8 0 0 8 0 5 4 5 0 0 4
      Based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japan Drug Design and Development conference, the topics in this volume cover almost every procedure and subdiscipline in the SAR discipline.They are categorized in three sections. Section one includes topics illustrating newer methodologies relating to ligand-receptor, molecular graphics and receptor modelling as well as the three-dimensional (Q)SAR examples with the active analogue approach and the comparative molecular field analysis. In section 2 the hydrophobicity parameters, log P (1-octanol/water) for compound series of medicinal-chemical interest are analysed physico-organic chemically. Section 3 contains the examples based on the traditional Hansch QSAR approach.A variety of methodologies and procedures are presented in this single volume, along with their methodological philosophies.

    • Modern Density Functional Theory: A Tool For Chemistry

      • 1st Edition
      • Volume 2
      • January 27, 1995
      • P. Politzer + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 0 8 7 4
      • eBook
        9 7 8 0 0 8 0 5 3 6 7 0 5
      Density Functional Theory (DFT) is currently receiving a great deal of attention as chemists come to realize its important role as a tool for chemistry. This book covers the theoretical principles of DFT, and details its application to several contemporary problems. All current techniques are covered, many are critically assessed, and some proposals for the future are reviewed. The book demonstrates that DFT is a practical solution to the problems standard ab initio methods have with chemical accuracy.The book is aimed at both the theoretical chemist and the experimentalist who want to relate their experiments to the governing theory. It will prove a useful and enduring reference work.

    • Adaption of Simulated Annealing to Chemical Optimization Problems

      • 1st Edition
      • Volume 15
      • August 1, 1995
      • J.H. Kalivas
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 4 0 4 9
      • eBook
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      Optimization problems occurring regularly in chemistry, vary from selecting the best wavelength design for optimal spectroscopic concentration predictions to geometry optimization of atomic clusters and protein folding. Numerous optimization tactics have been explored to solve these problems. While most optimizers maintain the ability to locate global optima for simple problems, few are robust against local optima convergence with regard to difficult or large scale optimization problems. Simulated annealing (SA) has shown a great tolerance to local optima convergence and is often called a global optimizer. The optimizaton algorithm has found wide use in numerous areas such as engineering, computer science, communication, image recognition, operation research, physics, and biology. Recently, SA and variations thereof have shown considerable success in solving numerous chemical optimization problems. The main thrust of this book is to demonstrate the use of SA in a wide range of chemical problems.The potentiality of SA, GSA and other modifications of SA to serve specific needs in a variety of chemical disciplines are covered. A detailed discussion on SA and GSA is given in Chapter 1, presenting the theoretical framework from which a computer program can be written by the reader. The remainder of the book describes applications of SA type algorithms to a diverse set of chemical problems. The final chapter contains an algorithm for GSA written in the MatLab programming environment. This program can be easily adapted to any optimization problem and with only slight modifications, can be altered to perform SA. A general flowchart is also given.

    • The Chemistry and Pharmacology of Taxol® and its Derivatives

      • 1st Edition
      • Volume 22
      • June 16, 1995
      • H. Timmerman
      • V. Farina
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 4 0 5 6
      • eBook
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      Taxol®, a naturally occurring diterpenoid is one of the most exciting antitumor drugs available today. Its current indications (refractory ovarian and metastatic breast cancer) may soon be expanded since the drug is showing activity against lung and head-and-neck cancers.The book opens with a review of the naturally occurring taxoids, a chapter which is not a comprehensive list of all taxoids isolated to date, but attempts a systematic approact to describing the different classes of taxoids, with particular reference to all skeletal types and the various functionality patterns. Biosynthetic studies are also discussed, as well as some of the basic chemistry and common functionalities of taxoidic skeleton. Structural identification of taxoids, mostly by spectroscopic means; the formulation of taxanes; the metabolism and pharmacokinetics of Taxol® are also discussed, as are the chemistry of taxanes in relation to SAR studies; SAR aspects of the phenylisoserine side chain; and the mode of action of the taxanes and the mechanisms of resistance.The book is therefore written for medical chemists, in order to stimulate further research in this area and to provide the reader with the necessary background information to start a research program in the area.

    • Structure, Fluctuation, and Relaxation in Solutions

      • 1st Edition
      • Volume 83
      • December 20, 1995
      • H. Nomura + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 3 9 6 7
      • eBook
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      The results of a special research project carried out for "Molecular Approaches to Non-equilibrium Process in Solution" were presented during The 42nd Yamada Conference on "Structure, Fluctuation and Relaxation in Solution" which was held from 11-15 December, 1994. The following topics were discussed at the conference:1. Solvation Dynamics 2. Relaxation, Fluctuation and Reaction Dynamics 3. Dynamic Structure and Reaction Mechanisms in Solutions. These topics were the main concern of this conference.

    • Fortran Programs for Chemical Process Design, Analysis, and Simulation

      • 1st Edition
      • January 25, 1995
      • A. Kayode Coker
      • English
      • eBook
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      This book gives engineers the fundamental theories, equations, and computer programs (including source codes) that provide a ready way to analyze and solve a wide range of process engineering problems.

    • Preparation of Catalysts VI

      • 1st Edition
      • Volume 91
      • March 24, 1995
      • G. Poncelet + 4 more
      • English
      • eBook
        9 7 8 0 0 8 0 5 4 4 6 6 3
      The organizers of this Sixth Symposium maintained their initial objectives, namely to gather experts from both industries and universities to discuss the scientific problems involved in the preparation of heterogeneous catalysts, and to encourage as much as possible the presentation of research work on catalysts of real industrial significance. Another highlight of these symposia is to reserve a substantial part of the program to new developments in catalyst preparation, new preparation methods and new catalytic systems. The fact that chemical reactions which were hardly conceivable some years ago have become possible today through the development of appropriate catalytic systems proves that catalysis is in constant progress.The papers in this volume deal with preparation of new catalysts and supports, catalyst preparation via sol-gel methods, supported catalysts and synthesis of nanometer size catalysts.

    • Characterization and Chemical Modification of the Silica Surface

      • 1st Edition
      • Volume 93
      • April 25, 1995
      • E.F. Vansant + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 0 6 9 0
      • eBook
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      Oxide surface materials are widely used in many applications, in particular where chemically modified oxide surfaces are involved. Indeed, in disciplines such as separation, catalysis, bioengineering, electronics, ceramics, etc., modified oxide surfaces are very important. In all cases, the knowledge of their chemical and surface characteristics is of great importance for the understanding and eventual improvement of their performances. This book reviews the latest techniques and procedures in the characterization and chemical modification of the silica surface, presenting a unified and state-of-the-art approach to the relevant analysis techniques and modification procedures, covering 1000 references integrated into one clear concept.

    • Studies in Natural Products Chemistry

      • 1st Edition
      • Volume 17
      • July 24, 1995
      • Atta-ur Rahman
      • English
      • Hardback
        9 7 8 0 4 4 4 8 2 2 6 5 9
      • Paperback
        9 7 8 0 4 4 4 5 5 1 0 9 2
      • eBook
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      Rapid advances in chromatographic procedures, spectroscopic techniques and pharmacological assay methods have resulted in the discovery of an increasing number of new and interesting natural products from terrestrial and marine sources. The present volume contains comprehensive reviews on some of the major advances in this field which have taken place in recent years. The reviews include those on: novel metabolites from marine gastropods; the chemistry of marine natural products of the Halenaquinol family; secondary metabolites from Echinoderms and Bryozoans; triterpenoids and aromatic compounds from medicinal plants; chemistry and activity of sesquiterpenes from the genus Lactarius; the chemistry of bile alcohols; antifungal sesquiterpene dialdehydes; annonaceous acetogenins; nargenicin macrolides; and lignans and diarylheptanoids. Tropane alkaloids and phenolides formed by root cultures are also reviewed. Articles on natural Diels-Alder type adducts, the use of computer aided overlay for modelling the substrate binding domain of HLADH, applications of 170 NMR spectroscopy to natural product chemistry and the role of biological raw materials in synthesis are included. Volume 17 provides material of interest to natural products chemists.

Related subjects

Analytical chemistry

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Organic chemistry

Physical and theoretical chemistry

Spectroscopy