Skip to main content
Elsevier
View Cart

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

BooksJournals

    • Synthetic and Natural Phenols

      • 1st Edition
      • Volume 52
      • August 21, 1996
      • J.H.P. Tyman
      • English
      • Hardback
        9 7 8 0 4 4 4 8 8 1 6 4 9
      • Paperback
        9 7 8 0 4 4 4 5 5 1 3 3 7
      • eBook
        9 7 8 0 0 8 0 5 4 2 1 9 5
      The chemistry of phenols tends to be ignored in organic chemical textbooks and to be lost amongst the many classes of functional derivatives. This volume is not intended to provide a textbook approach but rather to give an account of developments in phenol chemistry in the last two decades.Features of this book:• Numerous phenolic systems have been covered in detail, e.g. phenolic propanoids.• The emphasis throughout has been on synthesis, on what can be achieved by the use of phenolic intermediates and in the construction of phenolic end products.• Many chapters enable the reader to refer to the original literature wherever possible.• Various chapters provide a fund of tutorial material and problems for undergraduate studies and further, which will encourage perusal of the literature. Some 2000 references to applied and academic papers are given.Phenols are ubiquitous substances and now it is more widely accepted that there are pros and cons connected with their usage. The pros for compounds are well-known and are illustrated by perennial panaceas such as aspirin, paracetamol, codeine, etc. The cons are less obvious because they are also materials deeply entrenched in our standard of living and in most cases inherent hazards have only recently come to light. The book will be of interest to postgraduate students in academic and industrial work.

    • Phosgene

      • 1st Edition
      • Volume 24
      • May 24, 1996
      • T.A. Ryan + 3 more
      • English
      • eBook
        9 7 8 0 0 8 0 5 3 8 8 0 8
      Phosgene, COCl2 is a C1 chemical of major industrial importance. The annual production, worldwide, is more than 1 million tons; 90% of which is used in the manufacture of isocyanates and of polyurethane and polycarbonate resins. Phosgene is also extensively used as a synthetic reagent in organic chemistry, in particular in the preparation of acyl chlorides, chloroformate esters, organic carbonates and carbamoyl chlorides.Although more than 7000 papers have appeared on phosgene and some 1000 papers on its analogues, this is the first book on these interesting chemicals. It presents a critical treatise of phosgene, ranging from its discovery and subsequent use as a war gas to some potential applications of the material into the 21st century. It includes chapters on biological effects and industrial hygiene; on synthesis, formation and manufacture; analysis, uses, environmental effects, and physical and thermodynamic properties. Reactions with organic and inorganic materials are described. Four of the seventeen chapters are devoted to a description of the carbonyl halides (especially carbonyl difluoride) related to phosgene, and a special section deals collectively with the electronic structures of carbonyl halide molecules.Featuring the first-ever comprehensive discussion of the medical effects of phosgene poisoning and the most modern methods of treating exposure victims, the book will be of interest to historians and militarists and those working in the chemical industries (heavy chemicals, agricultural and pharmaceutical), university libraries, hospitals, medical research centres, museums, environmental research centres, poison units and health and safety institutions world-wide.

    • Vibrational Intensities

      • 1st Edition
      • Volume 22
      • November 22, 1996
      • B.S. Galabov + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 0 5 3 9
      • eBook
        9 7 8 0 0 8 0 5 4 3 5 5 0
      The current volume is a single topic volume on the vibrational intensities in the infrared and Raman spectra. Vibrational intensities in infrared and Raman spectra are important physical quantities that are directly related to the distribution and fluctuations of electric charges in the molecule. These spectral parameters can be experimentally determined with good accuracy for many molecules. Additionally, infrared and Raman intensities are presently estimated theoretically by advanced analytical derivative ab initio molecular orbital methods. These fundamental molecular quantities are being used in structural, and other studies, on a limited basis.Features of this book- Presents in a systematic way, the theoretical approaches that are used in analyzing and predicting vibrational intensities- The formalisms developed are illustrated with detailed numerical examples- Most of the theoretical models described were obtained and then applied to chosen molecules- A consistent notation is used in presenting the different theoretical approaches, thus eliminating another barrier in understanding some methods, especially those developed by the Russian spectroscopic school.

    • Equilibria and Dynamics of Gas Adsorption on Heterogeneous Solid Surfaces

      • 1st Edition
      • Volume 104
      • December 17, 1996
      • W.A. Steele + 2 more
      • English
      • eBook
        9 7 8 0 0 8 0 5 3 1 1 9 9
      The fact that the surfaces of real solids are geometrically distorted and chemically non-uniform has long been realized by the scientists investigating various phenomena occurring on solid surfaces. Even in the case when diffraction experiments show a well-organized bulk solid structure, the surface atoms or molecules will usually exhibit a much smaller degree of surface organization. In addition to the results obtained from electron diffraction, this can be seen in the impressive images obtained from STM and AFM microscopies. This geometric and chemical disorder is the source of the energetic heterogeneity for molecules adsorbing on real solid surfaces. Hundreds of papers have been published showing that this heterogeneity is a major factor in determining the behaviour of real adsorption systems.Studies of adsorption on energetically heterogeneous surfaces have proceeded along three somewhat separate paths, with only minor coupling of ideas. One was the study of adsorption equilibria on heterogeneous solid surfaces. The second path was the study of time evolution of adsorption processes such as surface diffusion or adsorption-desorptio... kinetics on heterogeneous surfaces, and the third was the study of adsorption in porous solids, or more generally, adsorption in systems with limited dimensions. The present monograph is a first attempt to provide a synthesis of the ways that surface geometric and energetic heterogeneities affect both the equilibria and the time evolution of adsorption on real solids. The book contains 17 chapters written by a team of internationally recognized specialists, some of whom have already published books on adsorption.

    • Alkaloids: Chemical and Biological Perspectives

      • 1st Edition
      • Volume 10
      • May 20, 1996
      • S.W. Pelletier
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 2 4 7 2
      • eBook
        9 7 8 0 0 8 0 5 2 6 9 9 7
      Volume 10 of this series presents four timely reviews. Chapter 1 provides a fascinating account of the history of alkaloid discovery in Australia beginning with the isolation of the first alkaloid from an Australian plant, the Tasmanian sassafras (Atherosperma moschatum), by Zeyer in 1861. Also included is a comprehensive survey of alkaloid-bearing plants, and a section dealing with detection, estimation, extraction, and work-up procedures for alkaloids.Chapter 2 provides a comprehensive update to the chapter on "Pyridine and Piperidine Alkaloids" which appeared in volume 3 of this series. The focus of this chapter is on new alkaloids isolated, biosynthesis, and biological properties.Chapter 3 looks at "3-Alkylpiperidine Alkaloids Isolated from Marine Sponges in the Order Haplosclerida". Studies over the past thirty years have shown that sponges are a rich source of alkaloids. Many of these sponge alkaloids are related to each other by the presence of a 3-alkylpiperidine moiety in their structures and it happens that the sponges that have been reported to contain 3-alkylpiperidine alkaloids are all in the order Haplosclerida.Chapte... 4 reviews &bgr;-carboline and isoquinoline alkaloids which are pharmacologically some of the most significant marine natural products. This chapter treats the isolation, structure elucidation, synthesis, biosynthesis, and pharmacological activity of these alkaloids.

    • Nonlinear Computer Modeling of Chemical and Biochemical Data

      • 1st Edition
      • January 24, 1996
      • James F. Rusling + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 9 1 5 5 3
      • Hardback
        9 7 8 0 1 2 6 0 4 4 9 0 4
      • eBook
        9 7 8 0 0 8 0 5 3 7 6 8 9
      Assuming only background knowledge of algebra and elementary calculus, and access to a modern personal computer, Nonlinear Computer Modeling of Chemical and Biochemical Data presents the fundamental basis and procedures of data modeling by computer using nonlinear regression analysis. Bypassing the need for intermediary analytical stages, this method allows for rapid analysis of highly complex processes, thereby enabling reliable information to be extracted from raw experimental data.By far the greater part of the book is devoted to selected applications of computer modeling to various experiments used in chemical and biochemical research. The discussions include a short review of principles and models for each technique, examples of computer modeling for real and theoretical data sets, and examples from the literature specific to each instrumental technique.The book also offers detailed tutorial on how to construct suitable models and a score list of appropriate mathematics software packages.

    • NMR of Polymers

      • 1st Edition
      • October 22, 1996
      • Frank A. Bovey + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 9 1 2 0 6 0
      • Hardback
        9 7 8 0 1 2 1 1 9 7 6 5 0
      • eBook
        9 7 8 0 0 8 0 5 3 7 5 8 0
      NMR has made important contributions to our understanding of structure–property relationships in polymers. This book provides an up-to-date and comprehensive overview of the fundamentals of NMR, with applications of multidimensional NMR and the new solution and solid-state methods in polymer science. NMR of Polymers is written by leading authorities for graduate students and professionals in academia and industry.

    • Neural Networks in QSAR and Drug Design

      • 1st Edition
      • August 9, 1996
      • James Devillers
      • English
      • Paperback
        9 7 8 0 1 2 3 8 8 4 5 9 6
      • eBook
        9 7 8 0 0 8 0 5 3 7 3 8 2
      Comprehensive and impeccably edited, Neural Networks in QSAR and Drug Design is the first book to present an all-inclusive coverage of the topic. The book provides a practice-oriented introduction to the different neural network paradigms, allowing the reader to easily understand and reproduce the results demonstrated. Numerous examples are detailed, demonstrating a variety of applications to QSAR and drug design.The contributors include some of the most distinguished names in the field, and the book provides an exhaustive bibliography, guiding readers to all the literature related to a particular type of application or neural network paradigm. The extensive index acts as a guide to the book, and makes retrieving information from chapters an easy task. A further research aid is a list of software with indications of availablility and price, as well as the editors scale rating the ease of use and interest/price ratio of each software package. The presentation of new, powerful tools for modeling molecular properties and the inclusion of many important neural network paradigms, coupled with extensive reference aids, makes Neural Networks in QSAR and Drug Design an essential reference source for those on the frontiers of this field.

    • Raman Microscopy

      • 1st Edition
      • June 24, 1996
      • George Turrell + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 1 8 9 6 9 0 4
      • eBook
        9 7 8 0 0 8 0 5 4 0 2 5 2
      One of the first books devoted entirely to the subject of Raman microscopy, Raman Microscopy addresses issues of great interest to engineers working in Raman-microscope development and researchers concerned with areas ofapplication for this science. The book is written by several world recognized experts, who summarize the Raman effect before discussing the hardware and software involved in todays instruments. This format provides an excellent introduction to this up-and-coming discipline. All important applications, including those in materials science and earth science are covered in depth.

    • Development and Validation of Analytical Methods

      • 1st Edition
      • Volume 3
      • May 29, 1996
      • Christopher M. Riley + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 5 2 3 1 0
      • eBook
        9 7 8 0 0 8 0 5 3 0 3 5 2
      The need to validate an analytical or bioanalytical method is encountered by analysts in the pharmaceutical industry on an almost daily basis, because adequately validated methods are a necessity for approvable regulatory filings. What constitutes a validated method, however, is subject to analyst interpretation because there is no universally accepted industry practice for assay validation. This book is intended to serve as a guide to the analyst in terms of the issues and parameters that must be considered in the development and validation of analytical methods. In addition to the critical issues surrounding method validation, this book also deals with other related factors such as method development, data acquisition, automation, cleaning validation and regulatory considerations. The book is divided into three parts. Part One, comprising two chapters, looks at some of the basic concepts of method validation. Chapter 1 discusses the general concept of validation and its role in the process of transferring methods from laboratory to laboratory. Chapter 2 looks at some of the critical parameters included in a validation program and the various statistical treatments given to these parameters.Part Two (Chapters 3, 4 and 5) of the book focuses on the regulatory perspective of analytical validation. Chapter 3 discusses in some detail how validation is treated by various regulatory agencies around the world, including the United States, Canada, the European Community, Australia and Japan. This chapter also discusses the International Conference on Harmonization (ICH) treatment of assay validation. Chapters 4 and 5 cover the issues and various perspectives of the recent United States vs. Barr Laboratories Inc. case involving the retesting of samples. Part Three (Chapters 6 - 12) covers the development and validation of various analytical components of the pharmaceutical product development process. This part of the book contains specific chapters dedicated to bulk drug substances and finished products, dissolution studies, robotics and automated workstations, biotechnology products, biological samples, analytical methods for cleaning procedures and computer systems and computer-aided validation. Each chapter goes into some detail describing the critical development and related validation considerations for each topic.This book is not intended to be a practical description of the analytical validation process, but more of a guide to the critical parameters and considerations that must be attended to in a pharmaceutical development program. Despite the existence of numerous guidelines including the recent attempts by the ICH to be implemented in 1998, the practical part of assay validation will always remain, to a certain extent, a matter of the personal preference of the analyst or company. Nevertheless, this book brings together the perspectives of several experts having extensive experience in different capacities in the pharmaceutical industry in an attempt to bring some consistency to analytical method development and validation.

Related subjects

Analytical chemistry

Chemistry general

Inorganic chemistry

Organic chemistry

Physical and theoretical chemistry

Spectroscopy