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Books in Organic synthesis

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Organofluorine Compounds in Biology and Medicine

  • 1st Edition
  • January 25, 2015
  • V Prakash Reddy
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 3 7 4 8 - 5
  • eBook
    9 7 8 - 0 - 4 4 4 - 5 3 7 4 9 - 2
Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area.

Writing Reaction Mechanisms in Organic Chemistry

  • 3rd Edition
  • July 10, 2014
  • Kenneth A. Savin
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 4 1 1 4 7 5 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 0 5 0 9 - 6
Writing Reaction Mechanisms in Organic Chemistry, Third Edition, is a guide to understanding the movements of atoms and electrons in the reactions of organic molecules. Expanding on the successful book by Miller and Solomon, this new edition further enhances your understanding of reaction mechanisms in organic chemistry and shows that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. The book has been extensively revised with new material including a completely new chapter on oxidation and reduction reactions including stereochemical reactions. It is also now illustrated with hundreds of colorful chemical structures to help you understand reaction processes more easily. The book also features new and extended problem sets and answers to help you understand the general principles and how to apply these to real applications. In addition, there are new information boxes throughout the text to provide useful background to reactions and the people behind the discovery of a reaction. This new edition will be of interest to students and research chemists who want to learn how to organize what may seem an overwhelming quantity of information into a set of simple general principles and guidelines for determining and describing organic reaction mechanisms.

Strategies and Tactics in Organic Synthesis

  • 1st Edition
  • Volume 10
  • July 10, 2014
  • Michael Harmata
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 1 7 1 8 5 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 7 1 9 1 - 6
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, we are given stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done, and we are educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

Comprehensive Organic Synthesis

  • 2nd Edition
  • February 14, 2014
  • Paul Knochel + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 0 8 - 0 9 7 7 4 2 - 3
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 7 7 4 3 - 0
The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts.

Nitration of Hydrocarbons and Other Organic Compounds

  • 1st Edition
  • October 22, 2013
  • A. V. Topchiev
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 4 3 8 - 8
Nitration of Hydrocarbons and Other Organic Compounds tackles various concerns in the process of substituting hydrogen atoms in the aromatic or heterocyclic nucleus, or in saturated hydrocarbon, by nitro groups. The title first covers the nitration of aromatic and heterocyclic compounds with nitric acid and nitrating mixture, and then proceeds to discussing the mechanism of the nitration of aromatic compounds with nitric acid and nitrating mixture. Next, the selection deals with the nitration of saturated, aromatic-aliphatic and unsaturated hydrocarbons with nitric acid. The text also talks about the nitration with nitrogen oxides, along with the nitration of amines. The last chapter details the nitration of organic compounds with organic and inorganic nitrates and nitroxyl. The book will be of great interest to students, researchers, and practitioners of organic chemistry.

Selenium Reagents & Intermediates in Organic Synthesis

  • 1st Edition
  • Volume 4
  • September 29, 1986
  • C. Paulmier
  • Patrick Perlmutter
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 6 4 0 - 2
The explosive growth of organoselenium chemistry over the past 12 years can be attributed to the specific properties of organic selenium molecules, which fit the requirements of modern organic synthesis. Most of them are well adapted to chemo-, regio- and stereo-selectivities. In addition, they can be used in mild experimental conditions which are compatible with the stability of both substrates and products in the preparation of unsaturated and functional complex molecules, especially in the field of natural products. This book describes and illustrates different synthetic routes to organic structures using selenium reagents or intermediates. The approach emphasizes that such transformations are simple, efficient and often carried out at room temperature. The scope ranges from the preparation of both inorganic and organic selenium reagents, through descriptions of structure, toxicity, biological aspects and nuclear magnetic resonance, to applications of specific selenium compounds in various syntheses including natural products and biologically active compounds.

Synthesis of Optically Active Alpha-Amino Acids

  • 1st Edition
  • Volume 7
  • September 30, 1989
  • R. M. Williams
  • Patrick Perlmutter
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 9 2 9 5 - 3
The purpose of this book is to review and critically evaluate the best new methods to synthesize alpha-amino acids in optically active form. There is so much new literature on amino acid synthesis that the experimentalist will undoubtedly have difficulty in selecting the most appropriate methodology for constructing the amino acid of immediate interest. This book is a guide for steering the scientist through the maze of existing reports on the subject and contains the most up-to-date critical reviews of methods of asymmetric synthesis of amino acids. In areas that are relatively new conceptually and less studied experimentally, an effort has been made to review the most salient works with an eye towards future development. Over 330 schemes and figures are presented with references for rapid visual retrieval of information. The book will be of great value to academic and industrial organic research chemists, especially those concerned with medicinal and agricultural chemistry, as well as to graduate and post graduate students, biochemists and biologists.

Organic Syntheses Based on Name Reactions and Unnamed Reactions

  • 1st Edition
  • Volume 11
  • October 22, 2013
  • Alfred Hassner + 1 more
  • Patrick Perlmutter
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 8 7 3 4 - 8
Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find.In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form.In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions.Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.

Sulphones in Organic Synthesis

  • 1st Edition
  • Volume 10
  • October 22, 2013
  • N S. Simpkins
  • Patrick Perlmutter
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 9 2 7 9 - 3
Over the last twenty years the use of sulphones in organic synthesis has increased dramatically, the synthetic repertoire of sulphones having been developed to such an extent as to rival the carbonyl functionality for versatility. Not only have sulphones been employed in a great many synthetic methodologies, enabling the preparation of a vast array of functionalised products, but the sulphone group has also proved to be of enormous value in many of the most demanding and sophisticated total syntheses carried out in recent years. This book describes in detail all of the important sulphone chemistry employed in organic synthesis, ranging from the well-established sulphone-mediated methods to less familiar sulphone reactions and very recent discoveries of synthetic potential.

Annual Reports in Organic Synthesis 1992

  • 1st Edition
  • Volume 1992
  • October 22, 2013
  • Philip M. Weintraub + 3 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 9 3 3 2 - 5
The Journal of the American Chemical Society has aptly described this publication as an "aid to the harassed organic chemist who cannot keep up with the never-diminishing stream of new primary literature" and hails it "an outstandingly good buy."