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Organic Syntheses Based on Name Reactions and Unnamed Reactions
- 1st Edition, Volume 11 - October 22, 2013
- Authors: Alfred Hassner, C Stumer
- Editor: Patrick Perlmutter
- Language: English
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 8 7 3 4 - 8
Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but… Read more
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Request a sales quoteSynthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find.
In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form.
In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions.
Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.
For organic chemists, medicinal chemists, pharmaceutical company researchers, graduate students, university and industrial researchers.
Contains approximately 500 reactions listed alphabetically, of which a selection follows:
Alder: (Ene) Reaction. Baer - Fischer: Amino Sugar Synthesis. Barton: Deamination. Chan: Reduction of Acetylenes. Collman: Carbonylation Reagent. Dakin: Oxidation. Danheiser: Annulation. Ehrlich - Sachs: Aldehyde Synthesis. Evans: Chiral Auxiliary. Ferrier: Carbohydrate Synthesis. Fujiwara - Heck: Coupling. Gassman: Oxindole Synthesis. Haddadin - Issidorides: Quinoxaline Synthesis. Henbest: Iridium Reagent. Hoffman - Yamamoto: Stereoselctive Allylation. Isay: Pteridine Synthesis. Kabe: Chromanone Synthesis. Krief - Reich: Olefination. Lehn: Cryptand Synthesis. Leuckart - Wallace: Reductive Amination. McFadyen - Stevens: Ester Reduction. Nazarov: Cyclopentenone Synthesis. Olofson: Reagent. Pfitzinger: Quinoline Synthesis. Regitz: Diazo Transfer. Sakurai: Allylation. Scholtz: Indolizine Synthesis. Sharpless: Asymmetric Dihydroxylation. Stork: Reductive Cyclization. Suzuki: Vinyl Coupling. Tebbe: Olefination. Tsuji - Trost: Allylation. Ullmann - Fedvadjan: Acridine Synthesis. Van Boom: Phosphorylating Reagent. Vilsmeier - Haack - Viehe Reagent. Wacker - Tsuji: Olefin Oxidation. Wissner: Hydroxy Ketone Synthesis. Wolff: Rearrangement. Yamazaki: Cyanoaniline Synthesis. Zinke - Ziegler: Synthesis of Calixarenes. Names Index. Reagents Index. Reactions Index. Functional Group Transformations Index.
- Language: English
- Edition: 1
- Volume: 11
- Published: October 22, 2013
- Imprint: Pergamon
- eBook ISBN: 9781483287348
PP
Patrick Perlmutter
Patrick Perlmutter is Adjunct Professor of Chemistry at La Trobe University in Australia. He has been a university academic for 35 years with a highly active research group specialising in synthesis and new synthetic methods including conjugate additions, catalysis, total synthesis, medicinal chemistry and chemical biology. His research group has generated approximately 200 peer-reviewed publications in that time.
Affiliations and expertise
Adjunct Professor of Chemistry
La Trobe University, AustraliaAH
Alfred Hassner
Alfred Hassner was born in 1930. He survived the holocaust as a young child. After WW II, he enrolled to the Technische Hochschule in Vienna (1949-1951), and then received his BSc from the University of Nebraska (1952). He obtained his PhD under Norman Cromwell at the University of Nebraska (1956) and then was a postdoc with Louis Fieser at Harvard University. He joined the University of Colorado at Boulder (1957) and became a Full Professor at the age of 36 (1966). In 1975, he moved to SUNY at Binghamton and in 1983 he joined Bar-Ilan University in Israel, where he was professor and after retirement Professor Emeritus, until his sad demise recently (2024) at the age of 94.
Hassner mentored over 50 graduate students and more than 60 postdocs, published more than 320 research articles and 14 books and monographs, and has had a major impact on chemical science for the last 7 decades.
Some of his most known contributions include the stereoselective introduction of nitrogen functionalities into organic molecules, the synthesis of steroidal heterocycles and other biologically active targets. He was one of the first to recognize the application of NMR half-widths to stereochemical structure assignments before high resolution NMR became available. Many useful reagents and concepts in organic synthesis are registered to his name. For example, he first proposed the concept of regiochemistry and regioselectivity, now universally used terminologies in organic chemistry.
As a world-renowned expert in organic synthesis, he has held visiting professorships and appointments in many universities worldwide and also served as a valuable consultant for many industrial companies around the world.
Hassner served as the president of the Israel Chemical Society - ICS (1991-1994). In 2007, he received the ICS prize for Excellence. In 2016, he received Honorary membership award for his lifetime achievement and outstanding contributions.
Affiliations and expertise
Formerly, Professor, Bar-Ilan University, IsraelCS
C Stumer
Affiliations and expertise
Department of Chemistry
Bar-Ilan University
Ramat-Gan
IsraelRead Organic Syntheses Based on Name Reactions and Unnamed Reactions on ScienceDirect