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Books in Medicinal chemistry

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51-60 of 110 results in All results

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 53
  • January 31, 2014
  • G. Lawton + 1 more
  • English
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 3 3 9 5 - 8
Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems, including g-secretase modulators, P2X7 antagonists as therapeutic agents for CNS disorders, N-type calcium channel modulators for the treatment of pain, and more.

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 48
  • September 13, 2013
  • Manoj C Desai
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 4 1 7 1 5 0 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 7 1 5 1 - 0
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Bioconjugate Techniques

  • 3rd Edition
  • July 25, 2013
  • Greg T. Hermanson
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 8 2 2 3 9 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 2 2 4 0 - 6
Bioconjugate Techniques, Third Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

Introduction to Biological and Small Molecule Drug Research and Development

  • 1st Edition
  • May 7, 2013
  • C. Robin Ganellin + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 9 7 1 7 6 - 0
Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRecormon), anti-HIV protease inhibitor Darunavir, and more. Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and PhD), and as basic background reading for scientists in the pharmaceutical industry.

Volatile Biomarkers

  • 1st Edition
  • March 27, 2013
  • Cristina Davis + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 6 2 6 1 3 - 4
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 2 6 2 0 - 2
Volatile organic compounds (VOCs) in exhaled breath, sweat or urine carry much information on the state of human health. The role of VOCs in clinical diagnosis and therapeutic monitoring is expected to become increasingly significant due to recent advances in the field. Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine includes the latest discoveries and applications for VOCs from the world's foremost scientists and clinicians working in this emerging analytic area.

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 52
  • January 29, 2013
  • G. Lawton + 1 more
  • English
  • eBook
    9 7 8 - 0 - 4 4 4 - 6 2 6 7 1 - 4
Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.

The Immunoassay Handbook

  • 4th Edition
  • January 21, 2013
  • David Wild
  • English
  • Hardback
    9 7 8 - 0 - 0 8 - 0 9 7 0 3 7 - 0
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 7 0 3 8 - 7
The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation. The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip. This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry. Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing.www.immunoassayhandbook.com is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book. David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing.

Handbook of Infrared and Raman Spectra of Inorganic Compounds and Organic Salts

  • 1st Edition
  • December 2, 2012
  • Richard A. Nyquist + 1 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 7 8 5 2 - 2
Infrared Spectra of Inorganic Compounds is a comprehensive compendium of reference infrared spectra and empirical spectra-structure correlations of inorganic compounds in the solid phase. The majority of these compounds are (powdered) crystalline solids in which the crystallographic unit cell may contain several polyatomic ions or molecules. This book begins with an overview of the use of infrared spectroscopy in the identification of inorganic compounds. The experimental procedures for scanning the mid-infrared spectra are then described. The spectra are arranged to bring together compounds containing similar anions, in order to facilitate recognition of characteristic group frequencies. The arrangement is based on the position in the periodic table of the central atom in the anion. Two indices are provided, the first containing compounds as they appear in the book in numerical sequence, and the second arranged alphabetically by anion. Characteristic infrared frequencies and band intensities of the different anions are summarized, along with frequency assignments for the fundamental vibrations of complex anions taken from the literature. This monograph should be useful to physicists and inorganic chemists.

Organometallic Vapor-Phase Epitaxy

  • 1st Edition
  • December 2, 2012
  • Gerald B. Stringfellow
  • English
  • eBook
    9 7 8 - 0 - 3 2 3 - 1 3 9 1 7 - 5
Here is one of the first single-author treatments of organometallic vapor-phase epitaxy (OMVPE)--a leading technique for the fabrication of semiconductor materials and devices. Also included are metal-organic molecular-beam epitaxy (MOMBE) and chemical-beam epitaxy (CBE) ultra-high-vacuum deposition techniques using organometallic source molecules. Of interest to researchers, students, and people in the semiconductor industry, this book provides a basic foundation for understanding the technique and the application of OMVPE for the growth of both III-V and II-VI semiconductor materials and the special structures required for device applications. In addition, a comprehensive summary detailing the OMVPE results observed to date in a wide range of III-V and II-VI semiconductors is provided. This includes a comparison of results obtained through the use of other epitaxial techniques such as molecular beam epitaxy (MBE), liquid-phase epitaxy (LPE), and vapor phase epitaxy using halide transport.

Chitin, Chitosan, and Related Enzymes

  • 1st Edition
  • December 2, 2012
  • John Zikakis
  • English
  • eBook
    9 7 8 - 0 - 3 2 3 - 1 4 9 9 7 - 6
Chitin, Chitosan, and Related Enzymes documents the proceedings of a four-day joint United States-Japan seminar held at the University of Delaware. The said seminar is aimed to explore the potential of the application of chitin, chitosan, and related products in different scientific fields. The book is divided into six parts. Part I covers the application of chitin and chitosan to pharmaceutical preparations. Part II discusses the applications of chitin and its derivatives. Part III features chitin and chitosan in relation to enzymology and genetic engineering. Respectively covered in Parts IV, V, and VI are the chemical and physical structure of chitin and chitosan; biochemical and physiological properties of chitin and its derivatives; the effects of phosphate on chitin production; and the development of chitin as a suture as well as for orthopedic uses. The text is recommended for biochemists who would like to know more or make further studies about the different applications of chitin, chitosan, and related enzymes.