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Books in Life sciences

761-770 of 20318 results in All results

Principles of Immunotherapy in Breast and Gastrointestinal Cancers

  • 1st Edition
  • April 1, 2024
  • Michele Ghidini
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 1 3 3 7 6 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 3 3 7 5 - 6
Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance and New Sensitization Strategies presents updated research findings on immunotherapy, with a special focus on the mechanisms of resistance of those cancer types and how to overcome them. The book discusses topics such as tumor cell-intrinsic and extrinsic mechanisms of cancer resistance to immunotherapy, the role of currently available biomarkers, strategies to overcome therapeutic resistance, sensitizing agents for cancer resistance to cell mediated immunotherapy, immunotherapeutic approaches, mechanisms of resistance, and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer.This is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it.

Human Microbiome Drug Targets

  • 1st Edition
  • April 1, 2024
  • Genevieve Dable-Tupas + 3 more
  • English
  • Paperback
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  • eBook
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Human Microbiome Drug Targets: Modern Approaches in Disease Management presents fundamental information on the human microbiome, looking into the relationship between the microbiome and how it changes with specific diseases. Delving into the multifaceted roles of the microbiome in health and disease, the book's chapters discuss the role of the human microbiome in the pathophysiologic understanding of relevant diseases or disorders and their management. As changes in the human microbiome can provide clues to the probable cause and effect of diseases or disorders, as well as the impacts of therapy or intervention, this book is a welcomed addition to the existing research.Explaining how a better understanding of the microbiome and its impact on health and disease can pave the way for future discoveries leading to better health outcomes, this book will be of interest to drug developers, medicinal chemists, microbiologists, infectious disease specialists, biochemists, and students.

Health Effects of Indoor Air Pollution

  • 1st Edition
  • April 1, 2024
  • Mohammad Hadi Dehghani + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 6 0 9 0 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 6 0 9 1 - 2
Health Effects of Indoor Air Pollution, Volume Two, Air Pollution, Human Health, and the Environment is part of a three volume series. This volume covers the various classifications of indoor air pollutants and discusses the health impact of indoor pollutants, such as gaseous pollutants and particulate matter. It also examines epidemiological studies related to different air pollutants on health and the workplace. This book begins with an overview of classifications, sources, and occurrences of indoor air pollutants. It also examines the environmental and health impacts due to organic and inorganic air pollutants and how to mitigate them through exposure and risk management.Other sections explore “sick building syndrome,” which causes acute health and discomfort that appears to be linked to time spent in a building. Recent trends and control strategies for occupation exposure due to poor indoor air quality in industrial and nonindustrial workplaces to human health are also covered. This book is a valuable reference for academicians, researchers, and students in environmental health, public health, and occupational health, as well as environmental engineers, meteorologists, epidemiologists, medical researchers, and environmental toxicologists.

Fundamental Principles of Oxidative Stress in Metabolism and Reproduction

  • 1st Edition
  • April 1, 2024
  • Faiza Alam + 1 more
  • English
  • Paperback
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  • eBook
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Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management is a comprehensive resource for anyone needing awareness and recognition of oxidative stress as a basic component of disease to determine the precise treatment plan considering the cause of the disease. It describes the effects of oxidative stress in the human body, the detection of metabolic changes, psychological impact and effect on reproductive outcomes. In addition, it discusses alterations at the cellular level occurring due to oxidative stress along with the genetic aspects involved in its pathogenesis.

Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics

  • 1st Edition
  • April 1, 2024
  • Ting-Chao Chou
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 8 8 7 4 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 8 8 7 5 - 3
“Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” provides a comprehensive overview and update of the mass-action law-based unified dose-effect biodynamics, pharmacodynamics, bioinformatics, and the combination index theorem for synergy definition (MAL-BD/PD/BI/CI). Contents advocate the fundamental MAL-PD/BI/CI/BI principle for biomedical R&D, clinical trials protocol design computerized data analysis, illustrates the MAL-dynamics theory with sample analysis, and includes data entry and automated computer report print-outs. In 11 sections “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” leads the reader from an introduction and overview, to trial protocols and MAL-PD/CI approach for biomedical R&D in vitro and in animals. It describes the current Landscape of International FDA Drug Evaluation, Clinical Pharmacology, and Clinical Trials Guidance. This is a valuable resource for biomedical researchers, healthcare professionals, and students seeking to harness the power of data informatics in precision medicine.

Low-Temperature Processing of Food Products

  • 1st Edition
  • March 30, 2024
  • Seid Mahdi Jafari + 1 more
  • English
  • Paperback
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  • eBook
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Low-Temperature Processing of Food Products, Volume Seven in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for low-temperature processing of different food products. These processes are very important for achieving favorable sensory properties and energy usage. Divided in four sections, “Basics of low-temperature processing “, “Different types of cooling and freezing systems”, “Application of freezing in the food industry”, and “Design, control and efficiency of freezers”, all chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and relevant processing equipment to low-temperature unit operations.Written by experts in the field of food engineering, in a simple and dynamic way, this book targets industrial Engineers working in the field of food processing and within food factories to make them more familiar with the particular food processing operations and equipment.

Neurologie

  • 14th Edition
  • March 30, 2024
  • Jean Cambier + 3 more
  • French
  • Paperback
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  • Paperback
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  • eBook
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L’ouvrage• Devenu un « classique » dès sa première édition, l’Abrégé de neurologie présente, de façon claire, pratique et complète, les troubles neurologiques selon une approche sémiologique en s’appuyant sur l’anatomie et la physiologie et en intégrant les nouvelles connaissances apportées par la neuropsychologie et la neurogénétique. L’ouvrage décrit les affections neurologiques les plus fréquentes et propose une stratégie pour le diagnostic neurologique à la lumière de l’imagerie médicale et des explorations électrophysiologiques et métaboliques.• Cette 14e édition est entièrement revue et actualisée, en fonction notamment des évolutions des thérapeutiques et des méthodes diagnostiques. La structure de l’ouvrage a également été révisée, pour une meilleure lisibilité, en tenant compte des développements de certains sujets, et l’ajout de nouveaux chapitres : « Cervelet – Ataxies cérébelleuses », « Mouvements anormaux » et « Émotion, motivation, comportement et cognition ».• Cette nouvelle édition présente ainsi les connaissances actuelles en neurologie tout en conservant l’approche qui a fait la réputation de cet ouvrage : la place donnée la neurologie clinique et l’intégration de la sémiologie dans l’organisation structurelle et physiologique du système nerveux, dans le souci de les rendre compréhensibles pour tous.Le publicCet abrégé s’adresse aux étudiants de 2e et 3e cycles de médecine. Il intéressera également les neurologues et tous les praticiens confrontés à des symptômes ou à des troubles neurologiques.Les auteursJean Cambier † était membre de l’Académie de médecine et professeur de clinique neurologique.Maurice Masson est neurologue, professeur des universités.Catherine Masson est neurologue, praticien hospitalier.Henri Dehen † était professeur de neurologie.

A Multidisciplinary Approach to Managing Swallowing Dysfunction in Older People

  • 1st Edition
  • March 29, 2024
  • Pere Clave´ + 1 more
  • English
  • Paperback
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  • eBook
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A Multidisciplinary Approach to Managing Swallowing Dysfunction in Older People provides comprehensive coverage on oropharyngeal dysphagia (OD), focusing on older patient phenotypes. The book  provides the knowledge needed for translational researchers and professionals to aid in the detection, diagnosis, treatment and management of OD, ultimately improving patient quality of life. OD has been recently considered a geriatric syndrome because of its high prevalence, the increase of life-expectancy and the need to be managed by a multidisciplinary approach. This reference takes a novel approach to OD, covering all aspects as a geriatric syndrome, examining a complicated and multi-level topic in a succinct way. Contents include the most innovative information available in current literature combined with practical applications to improve the diagnosis and treatments of OD as a geriatric syndrome. This is the perfect reference for translational researchers, physicians and healthcare professionals dealing with OD.

Exosomal RNA

  • 1st Edition
  • March 29, 2024
  • Debalina Bhattacharya + 2 more
  • English
  • Paperback
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  • eBook
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Exosomal RNA: Role in Human Diseases and Therapy provides an in-depth study of exosomes and their RNA in the context of a variety of diseases. The book explores the diagnostic and therapeutic potential of exosomal RNA as biomarkers across a range of different conditions, including cancer, type 2 diabetes, cardiovascular and renal disease, as well as bacterial infections and tissue repair. The link between exosomal RNA expression and neurodegenerative disease is also explored. The book goes on to share the significance of exosomal RNA in preserving cellular function, with special attention given to their role in the autophagy process.This book also gives an overview of the isolation, characterization, and potential applications of exosomal RNA, providing researchers with an understanding of how they can be manipulated and utilized for the treatment of various diseases and conditions. This is an ideal reference for researchers in the field of molecular biology, cell biology, and related fields, as well as those involved in the development of therapeutics and personalized medicine.

Radiomics and Radiogenomics in Neuro-Oncology

  • 1st Edition
  • March 29, 2024
  • Sanjay Saxena + 1 more
  • English
  • Paperback
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  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 5 0 7 - 6
Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm, Volume One: Radiogenomics Flow Using Artificial Intelligence broadly encompasses the study of life-threatening brain and spinal cord malignancies, including primary lesions and those metastasizing to the central nervous system. Radiomics is an approach to medical imaging used to extract many quantitative imaging features using different data characterization algorithms, while radiogenomics, which has recently emerged as a novel mechanism in neuro-oncology research, focuses on the relationship of imaging phenotype and genetics of cancer. Sections in this book discuss several AI approaches that have been applied to conventional and advanced medical imaging data. These AI-based R-n-R tools have the potential to stratify patients into more precise initial diagnostic and therapeutic pathways and permit better dynamic treatment monitoring in this period of personalized medicine. While extremely promising, the clinical acceptance of R-n-R methods and approaches will primarily hinge on their resilience to non-standardization across imaging protocols and their capability to show reproducibility.