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    • Current Topics in Bioenergetics

      • 1st Edition
      • December 2, 2012
      • C.P. Lee
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 3 2 1 7
      • eBook
        9 7 8 0 3 2 3 1 5 1 2 2 1
      Current Topics in Bioenergetics, Volume 16 focuses on photosynthetic electron transfer, ATP-synthesizing reactions, and nitrogen fixation. It looks at the application of biochemistry and biophysics in the exploitation of gene isolation, sequencing, and analysis of structure and function. It also reviews photosystems I and II and electron transfer reactions in eukaryotic chloroplasts of more modern plants as well as in photosynthetic membranes of the very ancient cyanobacteria. Organized into seven chapters, this volume begins with an overview of photosystems I and II. Then, it discusses the ATP synthesis in chloroplasts, with special attention given to the genes and their protein products that produce the ATP synthase complexes of the plant mitochondria and chloroplasts. The reader is then introduced to the mechanism of proton gradient formation and calcium-gated control of the type of gradient formed, the evidence for localized domains of proton accumulation, the reaction center of purple bacteria, and the physical aspects of electron transfer. The final chapter examines the nitrogen fixation in plants and bacteria, with emphasis on the metabolic origins of the reducing power and ATP used in nitrogen fixation. Biophysicists, biochemists, and others interested in bioenergetics will find this book highly informative.

    • ADP-Ribosylation Reactions

      • 1st Edition
      • December 2, 2012
      • Osamu Hayaishi
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 3 8 4 7
      • eBook
        9 7 8 0 3 2 3 1 4 2 9 9 1
      ADP-Ribosylation Reactions: Biology and Medicine deals with the biochemical and physiological aspects of poly(ADP-ribose) and ADP-ribosylation of proteins. Topics covered range from pyridine nucleotide metabolism and ADP-ribosylation to the structure and properties of poly(ADP-ribose), along with acceptor proteins of poly(ADP-ribose). ADP-ribosyl protein linkages and poly(ADP-ribose) synthetase are also discussed. Comprised of 39 chapters, this book begins with a historical background on the discovery of poly(ADP-ribose) and the significance of poly- and mono(ADP-ribosyl)ati... reactions in molecular biology. The next section explores the role of ADP-ribosylation in NAD metabolism, paying particular attention to poly(ADP-ribose) synthetase-DNA interaction and the link between chromatin structure and poly(ADP-ribosyl)ati... Subsequent chapters focus on subfractions and subcellular distribution of mono(ADP-ribosyl) proteins in eukaryotic cells; polyadenylylation and ADP-ribosylation of reovirus proteins; poly(ADP-ribose) synthesis in plants; and immunohistochemistry of poly(ADP-ribose). The final chapter analyzes the ADP-ribosylation activity of toxin A and exoenzyme S in Pseudomonas aeruginosa. This monograph is written for students, practitioners, and researchers in fields such as molecular biology, medical chemistry, and biochemistry.

    • Allozyme Electrophoresis

      • 1st Edition
      • December 2, 2012
      • B. J. Richardson + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 9 6 9 7
      • eBook
        9 7 8 0 3 2 3 1 3 9 6 4 9
      Inherited enzyme variations, studied using electrophoresis, can be used as markers for the identification of individuals, population structure analysis, the delineation of species boundaries and phytogenetic reconstruction. The purpose of this book is to describe, in a single convenient handbook, all the theoretical and practical matters relevant to those intending to use electrophoresis as a tool for answering such questions.

    • Biology of Perceptual Systems

      • 1st Edition
      • December 2, 2012
      • Edward Carterette
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 3 4 2 5
      • eBook
        9 7 8 0 3 2 3 1 4 6 5 9 3
      Handbook of Perception, Volume III: Biology of Perceptual Systems reviews the literature on the biological aspects of human perception, with emphasis on perceptual systems and elements of sensory physiology. This volume is organized into 19 chapters and begins with a discussion of energy transduction, detection, and discrimination, along with the properties of neurons alone and as conjoined in nets. The focus then shifts to psychogenesis, the relatively new field of ethology, and the natural diversity and evolutionary divergence of sensory systems. The chapters that follow examine the genetics of behavior, the facts and theories about the way in which animals and men construct patterned stimulation of receptors into significant objects, and the structure and function of sensory systems on which vertebrates depend for their construction of the varieties of experience. The book methodically introduces the reader to chemoreception, tasting and smelling, cutaneous mechanoreception (of position, velocity, transients), active texture perception, mechanisms of spatial orientation and of motion in space, thermoreception, vision, and audition. In almost every case the underlying physiological mechanisms are related to the psychophysical or perceptual observations. This book is a valuable resource for psychologists, biologists, and natural scientists, as well as for those who are interested in the biology of human perception.

    • Cell Physiology Source book

      • 1st Edition
      • December 2, 2012
      • Nicholas Sperelakis
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 3 5 4 0
      • eBook
        9 7 8 0 3 2 3 1 4 2 6 9 4
      Cell Physiology Source Book provides a comprehensive discussion of physiology and biophysics at the cellular level. The book is organized into seven sections covering biophysical chemistry, electrochemistry, metabolism, second messengers, and ultrastructure (Section I); transport physiology, pumps, and exchangers (Section II); membrane excitability and ion channels (Section III); ion channels as targets for toxins, drugs, and genetic diseases (Section IV); synaptic transmission and sensory transduction (Section V); muscle and other contractile systems (Section VI); and bioluminescence and photosynthesis (Section VII). This text was written for graduate and advanced undergraduate students in the life sciences, including those taking courses in cell physiology, cell biophysics, and cell biology. Selected parts of this book can be used for courses in neurobiology, electrobiology, electrophysiology, secretory biology, biological transport, and muscle contraction. Students majoring in engineering, biomedical engineering, physics, and chemistry may use the book to understand the living state of matter. The text can serve as a reference tool for s postdoctoral scholars and faculty engaged in biological research. Medical, dental, and allied health students can also use this book to complement other textbooks in medical/mammalian physiology.

    • Botulinum Neurotoxin and Tetanus Toxin

      • 1st Edition
      • December 2, 2012
      • Lance Simpson
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 2 4 7 5
      • eBook
        9 7 8 0 3 2 3 1 4 1 6 0 4
      Botulinum Neurotoxin and Tetanus Toxin covers the mechanism of action, pathogenesis, and treatment of clostridial neurotoxins. The book is organized into four parts encompassing 18 chapters that discuss the origin, structure, pharmacology, toxicology, immunology, assays, and clinical issues of botulinum and tetanus neurotoxins. The introductory part of the book discusses the discovery and production of neurotoxins in various strains of Clostridium bacteria. This text also describes how specific bacteriophages and plasmids mediate the pathogenicity of some types of Clostridium botulinum and Clostridium tetani. The subsequent part provides an overview of issues related to toxin binding, including toxins that may serve as models for botulinum and tetanus neurotoxins. Discussions on the peripheral and central aspects of poisoning transport in the central nervous system and on the antagonistic drugs for clostridial neurotoxins are provided. The third part of the book addresses the antibodies against botulinum neurotoxin. Bioassay in mice and highly sensitive immunoassays, such as reversed passive hemagglutination, reversed passive latex agglutination, radioimmunoassay, and enzyme-linked immunosorbent assay, are presented. The concluding part covers the animal models for these toxins and discusses the diagnosis and treatment of botulism and tetanus in human. The clinical use of Clostridium botulinum toxin type A in ocular and neuromuscular disease is also examined. This book will be of value to protein chemists, microbiologists, virologists, pharmacologists, immunologists, and clinicians.

    • Neurobiology of Social Communication In Primates

      • 1st Edition
      • December 2, 2012
      • Horest Steklis
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 7 1 4 7
      • eBook
        9 7 8 0 3 2 3 1 5 5 2 0 5
      Neurobiology of Social Communication in Primates: An Evolutionary Perspective presents evidence on the neural basis of communicative behavior in primates, reevaluating the relationship between human language and animal communication in view of the linguistic abilities of chimpanzees. This book consists of 10 chapters. Chapter 1 discusses some of the persistent problems in evolutionary neurobiology of primate communication. The effects of brain lesions and stimulation on vocalization in New and Old World monkeys, relation between species differences in peripheral vocal structures and species contrasts in vocal performance, and anatomy and physiology of the nonhuman primate auditory system are reviewed in Chapters 2 to 4. Chapters 5 to 7 examine the effects of electrical brain stimulation on human verbal communication and facial expression, clinical data pertaining to language pathologies, and neural mechanisms of manual and oral control. The last three chapters summarize the materials presented in earlier chapters. This publication is recommended for neuroscientists, behavioral biologists, neurologists, psychiatrists, and students interested in the evolutionary heritage of human speech and language.

    • Kuwaiti Plants

      • 1st Edition
      • Volume 2
      • December 2, 2012
      • B.S. Middleditch
      • A.M. Amer
      • English
      • Paperback
        9 7 8 0 4 4 4 5 6 5 4 4 0
      • eBook
        9 7 8 0 4 4 4 5 9 8 4 9 3
      The people of Kuwait have in the past depended almost entirely on the sea trade giving its boat builders and sailors a good reputation. Plants in Kuwait were valued only as forage and fodder and for subsistence-level farming.Although oil was discovered in 1938, production of oil did not commence until after the second world war. Coupled with recent unrest in the region, extensive damage has been caused to many of Kuwait's plants and a good review of information on them became necessary. The book contains information on all of the dicothyledonous plants (except the Compositae) known to grow in Kuwait. Many of the species of plants are reviewed in their traditional uses in Kuwait and elsewhere. Extensive searches of scientific literature were carried out on phytochemistry, pharmacology, contemporary economic value of the plants. Brief notes are also provided on the utility of related species. The distribution of the 118 species covered is illustrated on maps of Kuwait and the Middle East.

    • Selected Topics in the History of Biochemistry

      • 1st Edition
      • Volume 35
      • December 2, 2012
      • G. Semenza
      • English
      • eBook
        9 7 8 0 4 4 4 5 9 8 2 0 2
      Selected Topics in the History of Biochemistry: Personal Recollections, I presents selected topics in the history of biochemistry based on the authors' personal recollections. These topics range from the isolation of Cori ester and the discovery of sugar nucleotides to the work of Frederick Gowland Hopkins (1861-1947). Ion-coupled membrane processes are also discussed, along with fructose and fructose-2,6-bisphos... well as lysosomes and glycogen. Comprised of 12 chapters, this volume begins with the discovery of Cori ester and the concept of phosphorolysis before turning to the discovery of sugar nucleotides and research on ion-coupled membrane processes. The reader is then introduced to studies of fructose, fructose-2,6-bisphos... lysosomes, and glycogen; the contributions of Frederick Gowland Hopkins in biochemistry; and a short autobiography of Juda Hirsch Quastel, with emphasis on his research work on the concept of active centers as a possible explanation of enzyme action and his investigation of the effects of malonic acid and substituted malonic acids on bacterial dehydrogenases. The remaining chapters focus on a biochemist's approach to autopharmacology; the early development of modern protein chemistry in Uppsala, Sweden; and the biographies of two Russian scientists, A. N. Bach and Sergei E. Severin. This monograph will be of interest to students, practitioners, and researchers in the field of biochemistry.

    • Biochemistry and Physiology of Protozoa

      • 2nd Edition
      • December 2, 2012
      • M Levendowsky
      • English
      • Paperback
        9 7 8 0 1 2 3 9 4 1 7 6 3
      • eBook
        9 7 8 0 3 2 3 1 6 1 6 8 8
      Biochemistry and Physiology of Protozoa, Second Edition, Volume 1 is organized into 13 chapters, beginning with a discussion on fine structure and phytogeny of phytoflagellates. This book discusses the structural features of protozoan cytochromes. Subsequent chapters explain sterol and carotenoid distributions in various groups, phycobiliproteins in cryptomonads, halotolerance in Dunaliella, physiology of coccolithophorids, the ameboflagellates, and bioluminescence of phytoflagellates. This edition also describes the most severe and best known of the toxins, saxitoxin, produced by species of Gonyaulax. Lastly, the physiological ecology of red tide flagellates is explained.

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