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Books in Life sciences

Gametogenesis
1st Edition
Volume 102
December 31, 2012
English
This new volume of Current Topics in Developmental Biology covers the area of gametogenesis, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as germline stem cells, signaling modalities during oogenesis in mammals, and genomic imprinting as a parental effect established in mammalian germ cells.
Fluorescence-Based Biosensors
From Concepts to Applications
1st Edition
Volume 113
December 31, 2012
English
One of the major challenges of modern biology and medicine consists in finding means to visualize biomolecules in their natural environment with the greatest level of accuracy, so as to gain insight into their properties and behaviour in a physiological and pathological setting. This has been achieved thanks to the design of novel imaging agents, in particular to fluorescent biosensors. Fluorescence Biosensors comprise a large set of tools which are useful for fundamental purposes as well as for applications in biomedicine, drug discovery and biotechnology. These tools have been designed and engineered thanks to the combined efforts of chemists and biologists over the last decade, and developed hand in hand together with imaging technologies. This volume will convey the many exciting developments the field of fluorescent biosensors and reporters has witnessed over the recent years, from concepts to applications, including chapters on the chemistry of fluorescent probes, on technologies for monitoring protein/protein interactions and technologies for imaging biosensors in cultured cells and in vivo. Other chapters are devoted to specific examples of genetically-encoded reporters, or to protein and peptide biosensors, together with examples illustrating their application to cellular and in vivo imaging, biomedical applications, drug discovery and high throughput screening.
Advances in Clinical Chemistry
1st Edition
Volume 59
December 31, 2012
English
Volume 59 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.
Epigenetic Regulation in the Nervous System
Basic Mechanisms and Clinical Impact
1st Edition
December 31, 2012
J. David Sweatt + 3 more
English
Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system.Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resili... to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions.Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia.
Proteomic Profiling and Analytical Chemistry
The Crossroads
1st Edition
December 31, 2012
Pawel Ciborowski + 1 more
English
Proteomic Profiling and Analytical Chemistry helps scientists without a strong background in analytical chemistry to understand basic analytical principles and apply them to proteomics profiling. In most proteomic profiling experiments, liquid chromatography is used; this method is also used widely in analytical chemistry. This book bridges the gap between overly specialized courses and books in mass spectrometry, proteomics and analytical chemistry. It also helps researchers with an analytical chemistry background to break into the proteomics field. Proteomic Profiling and Analytical Chemistry focuses on practical applications for proteomic research helping readers to design better experiments and to more easily interpret, analyze and validate the resulting data. Experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more are all covered in detail.
Seldin and Giebisch's The Kidney
Physiology and Pathophysiology
5th Edition
December 31, 2012
Robert J. Alpern + 2 more
English
A classic nephrology reference for over 25years, Seldin and Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin and Giebisch’s The Kidney is your number one source for information.
Nonclinical Study Contracting and Monitoring
A Practical Guide
1st Edition
December 31, 2012
William F. Salminen + 2 more
English
Nonclinical Study Contracting and Monitoring: A Practical Guide offers a systematic and straightforward handbook for obtaining high quality preclinical Good Laboratory Practice (GLP) studies. This book is full of real-world examples, processes, procedures, useful templates, checklists and sample reports to provide readers with a better understanding of exactly what happens during all stages of a GLP study and the critical aspects of GLP study design and conduct. Designed for both the novice and experienced scientist, this book covers the GLP regulations and how they impact preclinical studies, the differences between GLP, non-GLP and peer-reviewed studies, preclinical GLP study design, laboratory selection, contracts and business ethics, how to obtain test material for the study, animal sourcing and release for study, preparation of a draft report and much more. By illustrating the overall big picture and tying it together with the individual steps, this book is an essential resource to help scientists ensure a high quality GLP study that passes both scientific and regulatory scrutiny.
Designing Science Presentations
A Visual Guide to Figures, Papers, Slides, Posters, and More
1st Edition
December 31, 2012
Matt Carter
English
Designing Science Presentations guides researchers and graduate students of virtually any discipline in the creation of compelling science communication. Most scientists never receive formal training in the creation, delivery, and evaluation of such material, yet it is essential for publishing in high-quality journals, soliciting funding, attracting lab personnel, and advancing a career. This clear, readable volume fills that gap and provides visually intensive guidance at every step—from the construction of original figures to the presentation and delivery of those figures in papers, slideshows, posters, and websites. It provides pragmatic advice on the preparation and delivery of exceptional scientific presentations; demonstrates hundreds of visually striking presentation techniques, giving readers inspiration for creating their own; and is structured so that readers can easily find answers to particular questions.
The Dictionary of Cell and Molecular Biology
5th Edition
December 31, 2012
John M. Lackie
English
The Dictionary of Cell and Molecular Biology, Fifth Edition, provides definitions for thousands of terms used in the study of cell and molecular biology. The headword count has been expanded to 12,000 from 10,000 in the Fourth Edition. Over 4,000 headwords have been rewritten. Some headwords have second, third, and even sixth definitions, while fewer than half are unchanged. Many of the additions were made to extend the scope in plant cell biology, microbiology, and bioinformatics. Several entries related to specific pharmaceutical compounds have been removed, while some generic entries (“alpha blockers,” “NSAIDs,” and “tetracycline antibiotics,” for example), and some that are frequently part of the experimentalist’s toolkit and probably never used in the clinic, have been retained. The Appendix includes prefixes for SI units, the Greek alphabet, useful constants, and single-letter codes for amino acids.
Introduction to Forestry and Natural Resources
1st Edition
December 31, 2012
Donald L. Grebner + 2 more
English
Introduction to Forestry and Natural Resources presents a broad overview of the profession of forestry. The book details several key fields within forestry, including forest health, economics, policy, utilization, and forestry careers. Chapters deal specifically with forest products and harvesting, recreation, wildlife habitats, tree anatomy and physiology, and ethics. These topics are ideal for undergraduate introductory courses and include numerous examples (mainly graphical) and questions for students to ponder. Unlike other introductory forestry texts, which focus largely on forest ecology rather than practical forestry concepts, Introduction to Forestry and Natural Resources encompasses economic, ecological, and social aspects providing a uniquely balanced text. The wide range of experience of the contributing authors equips them especially well to identify missing content from other texts in the area and address topics currently covered in corresponding college courses.

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