Books in Life sciences

The Science and Art of Sensory Processing Sensitivity

1st Edition
July 25, 2024
Bianca P. Acevedo
English
Paperback
9 7 8 0 3 2 3 9 9 7 2 7 0
eBook
9 7 8 0 3 2 3 9 9 7 2 8 7

The Science and Art of Sensory Processing Sensitivity provides an up-to-date and novel scientific perspective on the biologically based Sensory Processing Sensitivity (SPS) trait— which is associated with enhanced awareness, depth of cognitive processing, and heightened responsivity to the environment and other individuals. This second volume by B.P. Acevedo, following “The Highly Sensitive Brain,” takes a scientific perspective on its exploration of SPS, but adds to the existing body of literature on high sensitivity by including an enhanced discussion on the proposed mechanisms linking it with depression, anxiety, and burnout.In addition, this second volume explores SPS’ relationship to other relevant personality traits, such as the Big Five, creativity, and sensation seeking; and sheds light on how their varying combinations give rise to different outcomes for highly sensitive persons (HSPs). A unique contribution of this volume is its detailed examination of the role of culture, gender, biology, aging, and the environment (including the workplace) on the expression (or repression) of high sensitivity.Also, unlike previous books, this volume takes a broad perspective on outcomes related to being highly sensitive to shine a light on the non-trivial issue plaguing many HSPs: diminished quality of life, happiness, and well-being. As such, a major contribution of the second volume on the science of SPS, is its extensive description of scientifically-based techniques that might improve the quality of life for those with high SPS.Thus, this volume may appeal to a wide audience, including both HSPs and those in their social network (friends, partners, physicians, parents, educators, and clinicians) who wish to better understand SPS, those with the trait, and how to enhance well-being among the highly sensitive.

Diagnostic, Prognostic, and Therapeutic Role of MicroRNAs in Head and Neck Cancer

1st Edition
July 25, 2024
Ashok Kumar + 3 more
English
Paperback
9 7 8 0 4 4 3 1 5 9 6 8 8
eBook
9 7 8 0 4 4 3 1 5 9 6 9 5

Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and treatment of HNSCC. The book encompasses various miRNA-based point-of-care diagnostics and drug delivery systems for HNSCC, along with information on clinical trials for improved clinical outcomes in HNSCC patients. In addition, it provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. Scientists and clinicians looking to win the battle against HNSCC will benefit from the book's sections on early diagnosis to improve treatment, increase treatment response rates, and reduce mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.

Alzheimer's Disease Research Guide

1st Edition
July 25, 2024
Takaomi C. Saido
English
Paperback
9 7 8 0 4 4 3 2 8 9 7 9 8
eBook
9 7 8 0 4 4 3 2 8 9 8 0 4

Alzheimer's Disease Research Guide: Animal Models for Understanding Mechanisms and Medications provides researchers with a comprehensive guide, detailing every aspect of Alzheimer's Disease research, including chapters on neuroinflammation, immunotherapy, biomarkers, and animal modeling. This book begins with historical perspectives of both pathological chronology and pathological biochemistry in relation to Alzheimer’s disease. Other chapters review Amyloidogenic AB and Non-Amyloidogenic tau and Metabolism of AB major components to the research and understanding of Alzheimer’s research. The book concludes with specific treatment chapters including how to develop safe, effective, and inexpensive medications and the application of genome editing to the treatment of Familial Alzheimer's Disease.Written by world renowned expert in Alzheimer’s research, this book is a valuable resource for all researchers.

Advances in Applied Microbiology

1st Edition
Volume 128
July 25, 2024
Geoffrey M. Gadd + 1 more
English
Hardback
9 7 8 0 4 4 3 2 9 5 5 8 4
eBook
9 7 8 0 4 4 3 2 9 5 5 9 1

Advances in Applied Microbiology, Volume 128 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1

1st Edition
Volume 2
July 24, 2024
Ufuk Cakatay + 2 more
English
Hardback
9 7 8 0 4 4 3 2 9 4 5 6 3
eBook
9 7 8 0 4 4 3 2 9 4 5 7 0

Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1 deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examine their relationship with aging aim to target deteriorating redox signaling cascades, and will also focus on promising therapeutic approaches. Understanding the indication for the use of new therapeutics targeting the illuminated pathways in wound healing will help adjust treatment regimens befitting modern medicine. Ineffective redox adaptation and disseminated oxidative injury are the hallmarks of continuing oxidative stress. However, oxidative stress cannot be simply described as the imbalance between ROS formation and antioxidant defense capacity; it also covers impairment in redox sensing and signaling pathways. The term oxidative stress is an expression that is losing its use in modern redox biology. It is now an accepted fact that ROS cannot be described as an apparent enemy or friend. Its optimum level modulates signal transduction and stress responses by acting as a second messenger for redox-sensitive cascades. Redox-dependent second messengers are generated in subcellular locations according to specific rules and regulations. Their appearance depends on cellular needs in response to external and internal stimuli variations. A good understanding of the wound healing cascades, which deteriorate especially in advancing ages, is critical in developing the most appropriate approach. To understand the redox signaling mechanisms and healing cascades in wound healing, to pioneer new pharmacoactive drugs that can be developed based on these mechanisms, to reveal the deteriorating dynamics in the elderly patient group, and to propose new treatment methods suitable for the advanced age group.

Hormones

1st Edition
Volume 142
July 23, 2024
Rossen Donev
English
Hardback
9 7 8 0 4 4 3 1 9 3 4 6 0
eBook
9 7 8 0 4 4 3 1 9 3 4 7 7

Hormones, Volume 142, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Estrogen receptor binding mechanism with agonist and antagonist, Biomarker Identification of Medullary Thyroid Carcinoma from Gene Expression Profiles Considering without-treatment and with-treatment Studies – A Bioinformatics approach, Exploring the Role of Estrogen and Progestins in Breast Cancer: A Genomic Approach to Diagnosis, Structural insights on ER-alpha, ER-Beta, progesterone and their drug-targets interactions in Breast cancer, The predictive ability of myokines in patients with chronic heart failure, and much more.Other chapters cover Endogenous and artificial regulators of pituitary glycoprotein hormone receptors, Insight into vitamin D3 action within the ovary - basic and clinical aspects, Hormonal basis of seasonal changes in metabolism, Viral mimicry and endocrine system: Divulging the importance in host-microbiome crosstalk, Recombinant hormones as biopharmaceuticals: past, present and future, Thyroid hormone biosynthesis and its role in brain development and maintenance, and much more.

Bio-organic Amendments for Heavy Metal Remediation

1st Edition
July 23, 2024
Allah Ditta + 3 more
English
Paperback
9 7 8 0 4 4 3 2 1 6 1 0 7
eBook
9 7 8 0 4 4 3 2 1 6 1 1 4

Bio-organic Amendments for Heavy Metal Remediation: Water, Soil and Plant Approaches and Technologies focuses on these core continuum media to explore remediation options using microbial, organic, and combined approaches. This volume in the Plant Biology, Sustainability and Climate Change series offers a comprehensive view of techniques and approaches for addressing contamination by heavy metals. It provides a comprehensive view of the challenge, with a focus on the bioremediation of heavy metals contamination using ecotechnological approaches for protecting the soil, water, and plant continuum.As anthropogenic activities increasingly negatively impact natural resources, there has been significant disturbance of the water, soil, and plant continuum due to the accumulation of heavy metals. The bioaccumulation of heavy metals in the food chain could pose life-threatening effects on plants as well as humans, and there is need to find effective and sustainable remediation options. The application of bio-organic amendments could serve as a sustainable solution to this problem.

Case-Based Practical Training of Colposcopy and Cervical Pathology

1st Edition
July 23, 2024
Nadereh Behtash + 5 more
English
Hardback
9 7 8 0 4 4 3 2 4 7 9 4 1
eBook
9 7 8 0 4 4 3 2 4 7 9 5 8

Case-Based Practical Training in Colposcopy and Cervical pathology: With Diagrams and Images is an illustrated reference to improve theoretical and practical knowledge to understand and perform colposcopy. Cervical cancer screening has advanced a great deal over the last century, and the medical field has come far in detect early pre-cancer and invasive cancer of the cervix though colposcopy and pathology. Anyone in the field of gynecology, pathology, and oncology will find this book useful to better understand the different levels of prevention, including vaccinations and screening and for students to correctly understand colposcopy and cervical pathology through real illustrated case studies. The book’s aim is for for prevention and treatment of anogenital and HPV related -diseases and supports the goal of the World Health Organization to cure cervical cancer by 2030.

Essentials of Translational Pediatric Drug Development

1st Edition
July 22, 2024
Elke Gasthuys + 3 more
English
Paperback
9 7 8 0 3 2 3 8 8 4 5 9 4
eBook
9 7 8 0 3 2 3 9 0 4 2 9 2

Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development. The book covers all key aspects from different stakeholder perspectives, providing a literature overview and careful reflection on state-of-the-art approaches. It will be an ideal guide for researchers in the field who are designing and performing high quality, innovative pediatric-adapted drug development by helping them define needs/challenges and possible solutions that advance and harmonize pediatric drug development.Despite the broad consensus that children merit the same quality of drug treatment as any other age group, children remain frequently neglected during drug research and development. Even with the adoption of multiple legislations addressing this problem, the lack of efficacy and safety data of marketed as well as newly developed drugs still remain in the pediatric population.

Metabolomics for Personalized Vaccinology

1st Edition
July 22, 2024
Mahbuba Rahman
English
Paperback
9 7 8 0 4 4 3 1 5 5 2 6 0
eBook
9 7 8 0 4 4 3 1 5 5 2 7 7

Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient’s health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host’s system is altered by vaccine administration.Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy.Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health