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Elsevier

Books in Life sciences

  • Giardia and Giardiasis - Part B

    • 1st Edition
    • Volume 107
    • English
    Giardia and Giardiasis Volume 107-Part B, in the Advances in Parasitology series, is dedicated to aspects of cytoskeletal structure of this parasite with an emphasis on insights of new components and their function in trophozoites. Further, microtubule function and its critical involvement in motility, attachment, mitosis and cell division as well as in transitions between developmental stages are reviewed. Also a comprehensive revision in the progress of tools to explore and understand the functional biology of Giardia, its coding and non-coding genes, features and cellular and molecular biology is contained in this volume. Additionally, an exciting perspective on the interactions between Giardia and intestinal epithelial cell by reviewing transcriptomic and proteomic investigations is included along with a state-of-the art of the understanding pathophysiology of giardiasis and of how Giardia can cause post-infectious and extra-intestinal complications. A complete review of current knowledge including commonly prescribed drugs, causes of therapeutic fails, drug resistance mechanisms, strategies for the discovery of new agents for alternative drug therapies is covered.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 95
    • English
    Advances in Clinical Chemistry, Volume 95, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release including sections on Advances in diagnostic microfluidics, Vascular and valvular calcification biomarkers, Long noncoding RNAs in cancer: From discovery to therapeutic targets, Exosomes of male reproduction, Tryptophan in health and disease, Biochemistry of blood platelet activation, and the beneficial role of plant oils in cardiovascular diseases.

  • Systems Simulation and Modeling for Cloud Computing and Big Data Applications

    • 1st Edition
    • Dinesh Peter + 1 more
    • English
    Systems Simulation and Modelling for Cloud Computing and Big Data Applications provides readers with the most current approaches to solving problems through the use of models and simulations, presenting SSM based approaches to performance testing and benchmarking that offer significant advantages. For example, multiple big data and cloud application developers and researchers can perform tests in a controllable and repeatable manner. Inspired by the need to analyze the performance of different big data processing and cloud frameworks, researchers have introduced several benchmarks, including BigDataBench, BigBench, HiBench, PigMix, CloudSuite and GridMix, which are all covered in this book. Despite the substantial progress, the research community still needs a holistic, comprehensive big data SSM to use in almost every scientific and engineering discipline involving multidisciplinary research. SSM develops frameworks that are applicable across disciplines to develop benchmarking tools that are useful in solutions development.

  • The Electronic Health Record

    Ethical Considerations
    • 1st Edition
    • Eike-Henner W. Kluge
    • English
    The Electronic Health Record: Ethical Considerations analyses the ethical issues that surround the construction, maintenance, storage, use, linkage, manipulation and communication of electronic health records. Its purpose is to provide ethical guidance to formulate and implement policies at the local, national and global level, and to provide the basis for global certification in health information ethics. Electronic health records (EHRs) are increasingly replacing the use of paper-based records in the delivery of health care. They are integral to providing eHealth, telehealth, mHealth and pHealth - all of which are increasingly replacing direct and personal physician-patient interaction - as well as in the developing field of artificial intelligence and expert systems in health care. The book supplements considerations that are raised by national and international regulations dealing with electronic records in general, for instance the General Data Protection Regulation of the European Union. This book is a valuable resource for physicians, health care administrators and workers, IT service providers and several members of biomedical field who are interested in learning more about how to ethically manage health data.

  • Cognitive Biases in Health and Psychiatric Disorders

    Neurophysiological Foundations
    • 1st Edition
    • Tatjana Aue + 1 more
    • English
    Cognitive Biases in Health and Psychiatric Disorders: Neurophysiological Foundations focuses on the neurophysiological basis of biases in attention, interpretation, expectancy and memory. Each chapter includes a review of each specific bias, including both positive and negative information in both healthy individuals and psychiatric populations. This book provides readers with major theories, methods used in investigating biases, brain regions associated with the related bias, and autonomic responses to specific biases. Its end goal is to provide a comprehensive overview of the neural, autonomic and cognitive mechanisms related to processing biases.

  • Neutron Crystallography in Structural Biology

    • 1st Edition
    • Volume 634
    • English
    Neutron Crystallography in Structural Biology, Volume 634, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this updated release include Fundamentals of neutron crystallography in structural biology, Large crystal growth for neutron protein crystallography, Prospects for membrane protein crystals in NMX, IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor, The macromolecular neutron diffractometer at the spallation neutron source, Current status and near future plan of neutron protein crystallography at J-PARC, Neutron macromolecular crystallography at the European spallation source, and much more.

  • Drying Atlas

    Drying Kinetics and Quality of Agricultural Products
    • 1st Edition
    • Werner Muhlbauer + 1 more
    • English
    Drying Atlas: Drying Kinetics and Quality of Agricultural Products provides, in a condensed and systematic way, specific insights on the drying-relevant properties and coefficients of over 40 agricultural products. It also presents information about the production methods that influence the drying process, the quality of the dried product, the official quality standards of the products, and the design principles and operating characteristics of drying systems that are widely used in the postharvest processing and food industry. Available books on drying technology mainly focus on drying theory and simulation of drying processes. This book offers systematic information on the impact of other important parameters, such as relative humidity, air flow rate, mechanical, thermal and chemical pre-treatment, and drying mode for specific products. It is a unique and valuable reference for scientists and engineers who want to focus on industrial drying applications and dryers, as well as graduate and post-graduate students in postharvest technology and drying.

  • The Neuroscience of Meditation

    Understanding Individual Differences
    • 1st Edition
    • Yi-Yuan Tang + 1 more
    • English
    The Neuroscience of Meditation: Understanding Individual Differences explores the individual differences in learning and practicing meditation, while also providing insights on how to learn and practice effectively. The book comprehensively covers the research in brain areas and networks that mediate the positive effects of meditation upon physical and mental health. Though it examines how people differ in how they learn and practice meditation, it underscores how underlying mechanisms differ in learning and practicing meditation and how they remain unclear to researchers. This book addresses the research gap and explores the brain science behind meditation.

  • Microbiomics

    Dimensions, Applications, and Translational Implications of Human and Environmental Microbiome Research
    • 1st Edition
    • English
    Microbiomics: Dimensions, Applications, and Translational Implications of Human and Environmental Microbiome Research describes a new, holistic approach to microbiomics. International experts provide in-depth discussion of current research methods for studying human, environmental, viral and fungal microbiomes, as well as the implications of new discoveries for human health, nutrition, disease, cancer research, probiotics and in the food and agricultural industries. Distinct chapters covering culturomics and sub-microbiomes, such as the viriome and mycetobiome, provide an integrative framework for the expansion of microbiomics into new areas of application, as well as crosspollination between research areas. Detailed case studies include the use of microbiomics to develop natural products with antimicrobial properties, microbiomic enhancements in food and beverage technology, microbes for bioprotection and biopreservation, microbial tools to reduce antibiotic resistance, and maintenance and cultivation of human microbial communities.

  • GPCR Signaling in Cancer

    • 1st Edition
    • Volume 145
    • English
    GPCR Signaling in Cancer, Volume 145, the latest release in the Advances in Cancer Research series, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effectors as case examples to highlight their fundamental understanding and therapeutic potential. Specific chapters address the Role of GRKs and beta-arrestins in cancer, Atypical GPCRs in cancer, the Role of a chemokine receptor (CCR) 5 in cancer, Targeting G protein-coupled receptors for therapeutics in cancer, Emerging GPCR signaling pathways in cancer, and more. G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors which are involved in nearly every cellular and physiological event. These receptors can recognize a broad array of ligands and they are targeted by nearly one third of the currently prescribed drugs including anti-cancer therapeutics.

  • Pharmacological Advances in Natural Product Drug Discovery

    • 1st Edition
    • Volume 87
    • English
    Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on Atherosclerosis Related Cells, A Review on Salvianolic Acid, Pharmacological Advances of Tanshinones, the Natural Product of Salvia Miltiorrhiza, Pharmacological Action and Potential Targets Analysis of Major Pharmacological Effects of Chlorogenic Acid, Modern TCM: Identifying and Defining the "Medicinal Mix", Pharmacological Advances in Astragaloside IV Derived from Astragalus Membranaceus, and much more.

  • Inflammatory Disorders - Part B

    • 1st Edition
    • Volume 120
    • English
    Inflammatory Disorders - Part B, Volume 120 explores inflammation in the immune system and how the body’s own cells or tissues may cause abnormal inflammation, thus resulting in chronic pain, redness, swelling, stiffness, and damage to normal tissues. Chapters in this updated volume include Proteins in monogenic autoinflammatory disorders, Virulence factors and their roles in periodontal disease pathogenesis, Role of Heat shock proteins in Inflammatory disorder Rheumatoid Arthritis, Novel targeted therapies for Crohn's disease: Recent progress and future perspectives, Dietary plant flavonoids in prevention of obesity and diabetes, Small RNAs in allergic diseases, Inflammation and inflammasome during ageing and age-related diseases, and more.

  • An Introduction to Interdisciplinary Toxicology

    From Molecules to Man
    • 1st Edition
    • Carey N. Pope + 1 more
    • English
    An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.

  • Genome Engineering via CRISPR-Cas9 System

    • 1st Edition
    • Vijai Singh + 1 more
    • English
    Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields.

  • Plant Small RNA

    Biogenesis, Regulation and Application
    • 1st Edition
    • Praveen Guleria + 1 more
    • English
    Plant Small RNA: Biogenesis, Regulation and Application describes the biosynthesis of small RNA in plant systems. With an emphasis on the various molecular mechanisms affected by small RNA and their applications in supporting plant growth and survival, this books presents the basics and most recent advancements in small RNA mediated plant genomics, metabolomics, proteomics and physiology. In addition, it emphasizes the various molecular mechanisms affected by small RNA and their applications in supporting plant growth and survival. Final sections cover the most recent advancements in small RNA mediated plant genomics, metabolomics, proteomics and physiology.

  • Advances in Immunology in China - Part B

    • 1st Edition
    • Volume 145
    • English
    Advances in Immunology in China - Part B, Volume 145, the latest release in the Advances in Immunology series, presents the latest release in a long-established and highly respected publication. The book includes current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on advances in immunology in China.

  • Advances in Cyanobacterial Biology

    • 1st Edition
    • Prashant Kumar Singh + 3 more
    • English
    Advances in Cyanobacterial Biology presents the novel, practical, and theoretical aspects of cyanobacteria, providing a better understanding of basic and advanced biotechnological application in the field of sustainable agriculture. Chapters have been designed to deal with the different aspects of cyanobacteria including their role in the evolution of life, cyanobacterial diversity and classification, isolation, and characterization of cyanobacteria through biochemical and molecular approaches, phylogeny and biogeography of cyanobacteria, symbiosis, Cyanobacterial photosynthesis, morphological and physiological adaptation to abiotic stresses, stress-tolerant cyanobacterium, biological nitrogen fixation. Other topics include circadian rhythms, genetics and molecular biology of abiotic stress responses, application of cyanobacteria and cyanobacterial mats in wastewater treatments, use as a source of novel stress-responsive genes for development of stress tolerance and as a source of biofuels, industrial application, as biofertilizer, cyanobacterial blooms, use in Nano-technology and nanomedicines as well as potential applications. This book will be important for academics and researchers working in cyanobacteria, cyanobacterial environmental biology, cyanobacterial agriculture and cyanobacterial molecular biologists.

  • Functional and Preservative Properties of Phytochemicals

    • 1st Edition
    • Bhanu Prakash
    • English
    Functional and Preservative Properties of Phytochemicals examines the potential of plant-based bioactive compounds as functional food ingredients and preservative agents against food-spoiling microbes and oxidative deterioration. The book provides a unified and systematic accounting of plant-based bioactive compounds by illustrating the connections among the different disciplines, such as food science, nutrition, pharmacology, toxicology, combinatorial chemistry, nanotechnology and biotechnological approaches. Chapters present the varied sources of raw materials, biochemical properties, metabolism, health benefits, preservative efficacy, toxicological aspect, safety and Intellectual Property Right issue of plant-based bioactive compounds. Written by authorities within the field, the individual chapters of the book are organized according to the following practical and easy to consult format: introduction, chapter topics and text, conclusions (take-home lessons), and references cited for further reading.

  • Protein Homeostasis Diseases

    Mechanisms and Novel Therapies
    • 1st Edition
    • Angel L. Pey
    • English
    Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-functi... and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders.

  • Aquaporin Regulation

    • 1st Edition
    • Volume 112
    • Gerald Litwack
    • English
    Aquaporin Regulation, Volume 112, the latest release in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters highlighting Perspectives on the evolution of aquaporin superfamily, Structure and dynamics of aquaporin-1, Selectivity and Transport in Aquaporins from Molecular Simulation Studies, Aquaporin regulation in metabolic organs, Phosphorylation of human AQP2 and its role in trafficking, Regulation of Aquaporin-2 by RNA Interference, Aquaporin Regulation: Lessons from Secretory Vesicles, CFTR Regulation of Aquaporin-mediated Water Transport, Glucocorticoid Gene Regulation of Aquaporin-7, and much more.

  • Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C

    • 1st Edition
    • Volume 633
    • English
    Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C, Volume 633, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial. This release includes sections on Next generation probes for molecular imaging in cells, Competitive binding assay for biotin and biotin derivatives, based on avidin and biotin-4-fluorescein... Converting avidin to bind ligands other than biotin, especially steroids, Chemoenzymatic Labeling Strategy, Engineered Siderophores, Small molecules to inhibit bacterial population behavior, NMR tube bioreactor, Small molecule controlled RAS activation system, Small molecule regulated Cas9, the Design and application of synthetic receptors, and much more.

  • Preclinical Research in Down Syndrome: Insights for Pathophysiology and Treatments

    • 1st Edition
    • Volume 251
    • English
    Preclinical Research in Down Syndrome: From Bench to Bedside, Volume 251, the latest release in the Progress in Brain Research series, highlights new advances in the field. Chapters in this updated release include Exploring genetic and epigenetic mechanisms underlying cognitive deficits in Dow syndrome, The trisomy paradox: gene expression dysregulation domains, the Influence of allelic differences in mouse models of Down syndrome, Modelling Down syndrome in cells: From stem cells to organoids, Modelling Down syndrome in animals from the early stage to the new generation of models, Mapping behavioral landscapes in Down syndrome animal models, and more.

  • Second Generation Cell and Gene-Based Therapies

    Biological Advances, Clinical Outcomes and Strategies for Capitalisation
    • 1st Edition
    • Alain Vertes + 3 more
    • English
    Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept of therapeutic cells (stem cells, genes, etc.), beyond the concept of vaccines, is reaching clinical trial, with mounting confidence in the safety and efficacy of these products. Nonetheless, numerous incremental technical advances remain to be achieved. Thus, this volume highlights the possible R&D paths, which will ultimately facilitate clinical delivery of cutting edge curative products.The next waves of innovation are reviewed in depth for hematopoietic stem cells, mesenchymal stem cells, tissue engineering, CAR-T cells, and cells of the immune system, as well as for enabling technologies such as gene and genome editing. Additionally, deep dives in product fundamentals, history of science, pathobiology of diseases, scientific and technological bases, and financing and technology adoption constraints are taken to unravel what will shape the cytotherapy industry to the horizon 2025 and beyond. The outcome is not simply a scientific book, but a global perspective on the nascent field combining science, business, and strategic fundamentals.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 91
    • Fidel Toldra
    • English
    Approx.322 pages

  • Handbook of Research on Blockchain Technology

    • 1st Edition
    • Saravanan Krishnan + 5 more
    • English
    Handbook of Research on Blockchain Technology presents the latest information on the adaptation and implementation of Blockchain technologies in real world business, scientific, healthcare and biomedical applications. The book's editors present the rapid advancements in existing business models by applying Blockchain techniques. Novel architectural solutions in the deployment of Blockchain comprise the core aspects of this book. Several use cases with IoT, biomedical engineering, and smart cities are also incorporated. As Blockchain is a relatively new technology that exploits decentralized networks and is used in many sectors for reliable, cost-effective and rapid business transactions, this book is a welcomed addition on existing knowledge. Financial services, retail, insurance, logistics, supply chain, public sectors and biomedical industries are now investing in Blockchain research and technologies for their business growth. Blockchain prevents double spending in financial transactions without the need of a trusted authority or central server. It is a decentralized ledger platform that facilitates verifiable transactions between parties in a secure and smart way.

  • Evidence-informed Approaches for Managing Dementia Transitions

    Riding the Waves
    • 1st Edition
    • Linda Garcia + 2 more
    • English
    Evidence-Informed Approaches for Managing Dementia Transitions provides evidence-informed approaches and future directions for supporting a higher quality of life for people living with dementia. Through a person-centered lens, this book equips care providers to better help people living with dementia align their expectations and hopes with the trajectories they can expect in their journey. It highlights the various transitions that those with dementia will experience and describes best practices for optimal adjustment to each. Topics covered include problem identification, driving cessation, loss of financial autonomy, acute hospital admission, moving to assisted living residences and long term care homes, and palliative and end of life care. This is a must have reference for researchers, clinicians, and mental health professionals (psychologists, counsellors, social workers, mental health nurses) as well as policy makers and other health and social care providers working with individuals with dementia.

  • Regulation of Nitrogen-Fixing Symbioses in Legumes

    • 1st Edition
    • Volume 94
    • English
    The Nitrogen-Fixing Legume-Rhizobium Symbiosis, Volume 94, the latest release in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on The diversity of legume-rhizobium symbioses, Parasponia; an evolutionary outlier of rhizobium symbiosis, Rhizobium diversity in the light of evolution, Genomes of rhizobia, Gene regulation by extracytoplasmic function (ECF) sigma factors in alpha-rhizobia, Early symbiotic signaling between Plant and Bacteria, Rhizobia infection, a journey to the inside of plant cells, Differentiation of symbiotic nodule cells and their rhizobium endosymbionts, Nodule Organogenesis, Nitrogen Fixation by the Legume-Rhizobium Symbiosis, and much more.

  • Sustainability of the Food System

    Sovereignty, Waste, and Nutrients Bioavailability
    • 1st Edition
    • Noelia Betoret + 1 more
    • English
    Sustainability of the Food System: Sovereignty, Waste, and Nutrients Bioavailability addresses the concept of global sustainability, focusing on three key areas of action within the food production system: food sovereignty, environmentally friendly food processes, and food technologies that increase the bioavailability of bioactive compounds. The book defines key concepts in the food production system and provides examples of specific and tailored actions that contribute to global sustainability. Sustainability of the Food System: Sovereignty, Waste, and Nutrients Bioavailability will serve as a welcomed resource for food scientists and technologists, agriculturists, agronomic engineers, food engineers, environmental technologists, nutritionists, and post-graduate students studying bioresource technology and sustainability.

  • Introduction to the Chemistry of Food

    • 1st Edition
    • Michael Zeece
    • English
    Introduction to the Chemistry of Food describes the molecular composition of food and the chemistry of its components. It provides students with an understanding of chemical and biochemical reactions that impact food quality and contribute to wellness. This innovative approach enables students in food science, nutrition and culinology to better understand the role of chemistry in food. Specifically, the text provides background in food composition, demonstrates how chemistry impacts quality, and highlights its role in creating novel foods. Each chapter contains a review section with suggested learning activities. Text and supplemental materials can be used in traditional face-to-face, distance, or blended learning formats.

  • Parkinson’s Disease Therapeutics

    Emphasis on Nanotechnological Advances
    • 1st Edition
    • Magisetty Obulesu
    • English
    Parkinson’s Disease Therapeutics: Emphasis on Nanotechnological Advances presents the latest information on the second most common neurodegenerative disorder in the elderly. Despite remarkable progress in various PD therapeutics, such as microRNAs and brain drug delivery systems, a few limitations impede their success. This book sheds light on the pros and cons of recently developed novel therapeutics. Very few books have highlighted the protective efficacy of natural products, antioxidants, and biomaterial design for other diseases.

  • Tumor Immunology and Immunotherapy - Cellular Methods Part B

    • 1st Edition
    • Volume 632
    • English
    Tumor Immunology and Immunotherapy – Cellular Methods Part B, Volume 632, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered include Quantitation of calreticulin exposure associated with immunogenic cell death, Side-by-side comparisons of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death, Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry, Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies, Methods to assess DC-dependent priming of T cell responses by dying cells, and more.

  • Advances in Agronomy

    • 1st Edition
    • Volume 160
    • Donald L. Sparks
    • English
    Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Saffron

    The Age-Old Panacea in a New Light
    • 1st Edition
    • Maryam Sarwat + 1 more
    • English
    Saffron: The Age-Old Panacea in a New Light is the first book to detail the functions and effect of saffron in medicinal situations. This book explores the medicinal aspects of saffron and the effect saffron imparts on various diseases of the central nervous system, cardiovascular system, digestive system, locomotor system, urogenital system, eye, skin, and immune system, along with their mechanism of action. This perpetual bulb found mainly in Asia and Europe, Iran, India and Mediterranean countries has been shown to reduce seizures, delay convulsions, and as a neuroprotective agent against cerebral ischemia, brain damage, and Alzheimer's and Parkinson's disease. In addition, it also reduces depression, hypnosis and anxiety and enhances learning and memory skills.

  • Inflammatory Disorders - Part A

    • 1st Edition
    • Volume 119
    • Rossen Donev
    • English
    Inflammation is a biological response triggered by different stimuli that has in the body a potentially damaging effect. In certain conditions, such as injury or infection, inflammation is a normal, healthy response. However, inflammatory disorders that result in the immune system attacking the body’s own cells or tissues may cause abnormal inflammation, which results in chronic pain, redness, swelling, stiffness, and damage to normal tissues. Mechanisms involved in promoting a number of different inflammatory disorders and their targeting for therapeutic benefit have been one of the hottest topics in last few decades. The two consecutive volumes (119 and 120) dedicated to this subject cover a wide spectrum of inflammatory disorders, mechanisms that are believed to cause them and different strategies for managing the inflammatory diseases.

  • Molecular Evolutionary Models in Drug Discovery

    • 1st Edition
    • Juan Bueno
    • English
    Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings.

  • Technology in Diabetes, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 49-1
    • Grazia Aleppo
    • English
    This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Grazia Aleppo, will cover key topics in Technology in Diabetes. This issue is one of four selected each year by our series consulting editor, Dr. Adriana G. Ioachimescu. Topics discussed in this issue will include: Evolution of Diabetes Technology, Diabetes Technology in children, Diabetes Technology in adults with type 1 and type 2 Diabetes, Benefits and challenges of Diabetes Technology use in older adults, Integration of Diabetes Technology in Clinical Practice, Diabetes Technology in the inpatient setting for management of hyperglycemia, Standardization of CGM reports, Diabetes Technology and Exercise, Psychosocial Aspects of Diabetes Technology use, Automated insulin delivery, and Glucagon, among others.

  • Priming-Mediated Stress and Cross-Stress Tolerance in Crop Plants

    • 1st Edition
    • Mohammad Anwar Hossain + 4 more
    • English
    Priming-Mediated Stress and Cross-Stress Tolerance in Crop Plants provides the latest, in-depth understanding of the molecular mechanisms associated with the development of stress and cross-stress tolerance in plants. Plants growing under field conditions are constantly exposed, either sequentially or simultaneously, to many abiotic or biotic stress factors. As a result, many plants have developed unique strategies to respond to ever-changing environmental conditions, enabling them to monitor their surroundings and adjust their metabolic systems to maintain homeostasis. Recently, priming mediated stress and cross-stress tolerance (i.e., greater tolerance to a second, stronger stress after exposure to a different, milder primary stress) have attracted considerable interest within the scientific community as potential means of stress management and for producing stress-resistant crops to aid global food security. Priming-Mediated Stress and Cross-Stress Tolerance in Crop Plants comprehensively reviews the physiological, biochemical, and molecular basis of cross-tolerance phenomena, allowing researchers to develop strategies to enhance crop productivity under stressful conditions and to utilize natural resources more efficiently. The book is a valuable asset for plant and agricultural scientists in corporate or government environments, as well as educators and advanced students looking to promote future research into plant stress tolerance.

  • The Genus Citrus

    • 1st Edition
    • Manuel Talon + 2 more
    • English
    The Genus Citrus presents the enormous amount of new knowledge that has been generated in recent years on nearly all topics related to citrus. Beginning with an overview of the fundamental principles and understanding of citrus biology and behavior, the book provides a comprehensive view from Citrus evolution to current market importance. Reporting on new insights supported by the elucidation of the citrus genome sequence, it presents groundbreaking theories and fills in previous knowledge gaps. Because citrus is among the most difficult plants to improve through traditional breeding, citrus researchers, institutions and industries must quickly learn to adapt to new developments, knowledge and technologies to address the biological constraints of a unique fruit-tree such as citrus. Despite the challenges of working with citrus, tremendous progress has been made, mostly through advances in molecular biology and genomics. This book is valuable for all those involved with researching and advancing, producing, processing, and delivering citrus products.

  • The Science of Grapevines

    • 3rd Edition
    • Markus Keller
    • English
    The Science of Grapevines, Third Edition reflects the latest insights into cultivar relationships, vascular transport, hormone action, and stress responses of grapevines. Based on the author’s many years of teaching, research and practical experience with grapevines and grape production, the book is completely revised and updated, presenting a comprehensive introduction on the physical structure of the grapevine, its organs, their functions, and their environmental interactions. While many concepts discussed are broadly applicable to plants in general, the focus is on grapevines, especially cultivated grapevines. This book enables readers to use these concepts in their own scientific research or in practical production systems. Scientifically grounded and integrating discoveries in other plant species, the book explores the physiological processes underlying grapevine form and function, their developmental and environmental control, and their implications for practical vineyard management.

  • Handbook of the Behavioral Neurobiology of Serotonin

    • 2nd Edition
    • Volume 31
    • English
    Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview of the many facets of behavioral serotonin research. The text expands on the two key topics, behavioral control (sensory processing, ultrasonic vocalization, and melatonin and sleep control) and psychiatric disorders, including its role on psychostimulant abuse and addiction. The new edition includes two new sections on the serotonin systems interactions and the involvement of serotonin in neurological disorders and associated treatment. Serotonin is a major neurotransmitters in the serotonergic system which one of the best studied and understood transmitter systems. Both are critically involved in the organization of all behaviors and in the regulation of emotion and mood.

  • Medical Semiology of the Digestive System Part II

    • 1st Edition
    • Manuela Stoicescu
    • English
    Medical Semiology of the Digestive System, Part II provides a comprehensive understanding of medical semiology in the digestive system. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers in the field. Each chapter incorporates a specific questionnaire with important questions that should be asked to patients in different situations to obtain valuable information that helps identify rare and unusual diseases. This unique feature of the book aims to facilitate the learning process among medical students, while also acting as a quick reference guide for clinicians in practice.

  • Invertebrate Embryology and Reproduction

    • 1st Edition
    • Fatma El-Bawab
    • English
    Invertebrate Embryology and Reproduction deals with the practical and theoretical objectives of the descriptive embryology of invertebrates, along with discussions on reproduction in these groups of animals. It explains several morphological and anatomical expressions in the field and covers the embryology of invertebrate animals, starting from the Protozoa, to the Echinodermata, the Protochordate and Tunicates. These groups include economically important aquatic invertebrates, such as crustaceans, as well as medically important invertebrates and economic arthropods. Each chapter is preceded by the taxonomy of the discussed phylum and/or the species to enable the reader to locate the systematic position.

  • The Neuromodulation Casebook

    • 1st Edition
    • Jeffrey Arle
    • English
    The Neuromodulation Casebook is a case-based volume for practical, hands-on decision-making using realistic case examples from the field of neuromodulation. It encompasses a variety of techniques and therapies, ranging from deep brain stimulation for a multitude of disorders, to spinal cord stimulation, peripheral nerve stimulation, cortical stimulation and cranial nerve stimulation, as well as non-invasive therapies and other implanted types of devices that interface with the nervous system. Allowing readers to better learn via case-based examples, this practical volume depicts real examples of decisions neuroscientists and neurosurgeons need to make every day from leaders in the field. This book serves as a companion text to the editor’s previous titles Essential Neuromodulation and Innovative Neuromodulation for neuroscience, neural engineering and biomedical engineering courses.

  • Gastrulation: From Embryonic Pattern to Form

    • 1st Edition
    • Volume 136
    • English
    Gastrulation: From Embryonic Pattern to Form Volume 136 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters on D. melanogaster, Zebrafish, Chick, Mouse and Human, C. elegans, D. melanogaster Internalization, Sea urchin, Ascidians, Xenopus Internalization, Xenopus Convergent Extension, Zebrafish Epiboly, Zebrafish Internalization, Zebrafish Convergence and Extension, Chick Primitive streak formation and mesendoderm internalization, Octavian Voiculescu, Mouse Primitive streak formation and internalization, Mouse Definitive endoderm morphogenesis, Conservation of movements, and more.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 94
    • English
    Advances in Clinical Chemistry, Volume 94, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest technologies relating to the field of clinical chemistry, with specific chapters in this new release covering Hypertensive disorders of pregnancy: Strategy to develop clinical peptide biomarkers for more accurate evaluation of the pathophysiological status of this syndrome, Clotting factors - Clinical biochemistry and their roles as plasma enzymes, Myokines: The endocrine coupling of skeletal muscle and bone, Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance, and more.

  • Saffron

    Science, Technology and Health
    • 1st Edition
    • Alireza Koocheki + 1 more
    • English
    Saffron: Science, Technology and Health summarizes the scientific, technical and health aspects of this crop. Saffron possesses unique agronomical, ecological, social and physiological characteristics. And, there are various chemical components present in saffron, including carbohydrates, minerals, vitamins, color pigment, aromatic and flavoring agents. Saffron has a long history of use in traditional medicine, and in recent years, the application of saffron in the medical industry as a cancer curing and antidepressant agent has brought more attention. There is also a growing trend of saffron use in the conventional food industry, including saffron desserts, cream, butter, beverages, powders, cake mixes and soups. Intended for nutrition scientists and scientists and technologists working in the areas of food, agriculture, new product development and pharmacology.

  • An Innovative Approach to Understanding and Treating Cancer: Targeting pH

    From Etiopathogenesis to New Therapeutic Avenues
    • 1st Edition
    • Tomas Koltai + 2 more
    • English
    An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve either a stable disease or even regression with no toxicity. The book discusses topics such as lactic acid and its transport system in the pH paradigm, mechanisms to decrease extra cellular pH and increase intracellular pH, NHE-1 activity in cancer, carbonic anhydrases, vacuolar ATPase proton pump, and the sodium-bicarbonate cotransporter system. Additionally, it discusses complementary pharmacological interventions, cellular acidification and extracellular alkalinization as a new and integral approach to cancer treatment.

  • Advances in Agronomy

    • 1st Edition
    • Volume 159
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 159, the latest release in this leading reference on agronomy, contains a variety of updates, including specific chapters on the Environmental Behavior of Glyphosate in Soil, Agriculture Contingency Plans for Managing Weather Aberrations and Extreme Climate Events: Development, Implementation and Impacts in India, Unmanned Aircraft Systems for Precision Weed Management Applications: Prospects and Challenges, Ratoon Rice Technology: A Green and Resource-Efficient Way for Rice Production, Growth Characteristics of Winter Wheat in China Based on GDD Comprehensive and Quantitative Analysis of Growth Characteristics of Winter Wheat in China Based on Growing Degree Days, and more.

  • Nanoarmoring of Enzymes with Carbon Nanotubes and Magnetic Nanoparticles

    • 1st Edition
    • Volume 630
    • English
    Nanoarchitectures Built with Carbon Nanotubes and Magnetic Nanoparticles, Volume 630, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters in this volume include updates from well-known, established leaders.

  • Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

    • 1st Edition
    • Volume 169
    • English
    Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientific importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.

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