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  • Biology of the Lymphokines

    • 1st Edition
    • Stanley Cohen + 2 more
    • English
    Biology of the Lymphokines discusses the scope and diversity of lymphokine research. This book focuses on the studies on lymphokines, such as those involving cellular source, chemical nature, purification strategies, and bioassay limitations. The mechanism of lymphokine action, lymphokines in vivo, and value of lymphokine quantitations are also covered. This text describes the repertoire of lymphokines produced by various lymphoblastoid cell lines and its significance for coping with the problem of large scale lymphokine production. The anti-viral and general immunoregulatory properties of interferons and rationale developed for integrating interferons with the family of lymphokines are likewise deliberated. This publication is a good source for students and researchers conducting work on lymphokines.

  • Problems of Cell Permeability

    International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences, Vol. 26
    • 1st Edition
    • A.S. Troshin
    • P. Alexander + 1 more
    • English
    Modern Trends in Physiological Science, Volume 26: Problem of Cell Permeability covers expounded sorptional theory of cell permerbeality. The problem of cell permeability deals with the questions connected with the laws of the entrance of substances from the surrounding medium into cells and the excretion from the latter of the products of intracellular metabolism. This book is composed of 12 chapters and begins with an overview of the chemical composition and structure of cell membrane, as well as the membrane theory of cell permeability. The next chapters treat the issues of cell’s osmometric activity and the physico-chemical properties of protoplasm as a system of coacervates. Considerable chapters are devoted to cell permeability for various substrates, such as non-electrolytes, organic acids, vital dyes, and mineral substances. The concluding chapters discuss the relationship between metabolism and cell permeability; the bioelectric properties of cell; and the protective action of non-electrolytes against live matter damage caused by dilute saline media. This book will be of value to cell biologists, biochemists, and research workers in cell permeability.

  • The Biology of Animal Viruses

    • 2nd Edition
    • Frank J. Fenner + 2 more
    • English
    The Biology of Animal Viruses, Second Edition deals with animal viruses focusing on molecular biology and tumor virology. The book reviews the nature, chemical composition, structure, and classification of animal viruses. The text also describes the methods of isolating animal viruses, how these are grown in the laboratory, assayed, purified, and used in biochemical experiments. The book also describes the structure and chemistry of many known viruses such as the papovaviridae, herpes virus, poxvirus, coronavirus, or the Bunyamwera supergroup. The book then explains the structure and function of the animal cell including the cytoplasmic organelles, the nucleus, inhibitors of cell function, and viral multiplication. Other papers discuss in detail the multiplication of the DNA and RNA viruses, whose mechanisms of multiplication differ from those of other viruses. Other papers discuss the known prevention and treatment methods of viral diseases, as well as the epidemiology and evolution of viral diseases resulting from human's disturbance of the biosphere and from medical and experimental innovations. The text can prove useful for immunologists, veterinarians, virologists, molecular researchers, students, and academicians in the field of cellular microbiology and virology.

  • Lymphokines

    A Forum for Immunoregulatory Cell Products
    • 1st Edition
    • Edgar Pick
    • English
    Lymphokines: A Forum for Immunoregulatory Cell Products, Volume 14, reviews the state of knowledge on lymphokines. The book opens with an integrative view of the role of lymphokines in the generation of fever. It stresses that pirogenicity is the attribute of more than one lymphokine: interleukin 1 (IL-1), interferon α, and tumor necrosis factor (TNF) all possess this quality. This is followed by separate chapters on the chemistry of IL-1 molecules and cloning of the gene for human monocyte IL-1; the production of lymphokine by cells of the central nervous system; the acute phase plasma protein response studied at the level of gene structure and expression; and the involvement of calcium and calcium-linked enzymes in T cell proliferation. Subsequent chapters deal with the involvement of pteridines in T cell activation; the discovery of cachectin and the establishment of its identity with TNF; the effect of IFN-γ and several cytotoxic cytokines on the proliferation, differentiation, and function of normal and leukemic myeloid cells; and the cytotoxic lymphokines produced by effector T cells. The final chapter discusses the ways in which chemically defined changes in cell membranes affect cell division.

  • Ultrastructure of the Kidney

    • 1st Edition
    • Albert J. Dalton + 1 more
    • English
    Ultrastructure in Biological Systems, Volume 2: Ultrastructure of the Kidney provides an overview of the state of knowledge on the ultrastructure of the mammalian kidney. The application of the electron microscope to studies of the kidney resulted in the demonstration of the hitherto undetected early thickening of the basement membrane of glomerular capillaries in glomerulonephritis. Yet many problems remain, particularly in relation to the correlation between function and the ultrastructure of components of the kidney—mesangium, glomerulus, juxtaglomerular apparatus, and the renal tubules. It is only recently that the mesangium has come to be accepted as real, and many questions remain as to the function of its cells. The existence of true membranes between foot processes of the epithelial cells of glomeruli is a newly established fact; but what this has to do with glomerular filtration is not known at present. Granules apparently secretory in nature have been identified in cells of the juxtaglomerular apparatus, but so far their presence has not been correlated with specific functional change. Artifacts introduced at fixation are now known to have considerable relevance in interpreting the ultrastructure of the normal nephron. These are paraphrased views of the contributors to this monograph who, while acquainting the reader with the research being carried on in these areas, have also brought into focus the many problems still awaiting solution.

  • Perspectives in Urban Entomology

    • 1st Edition
    • G. W. Frankie + 1 more
    • English
    Perspectives in Urban Entomology is a collection of papers presented at the "Ecology and Management of Insect Populations in Urban Environments" held in Washington, D.C. in 1976. This collection deals with urban entomology with emphasis on insects, insect-plant relationships, and arthropods in the urban environments. One paper examines the causes why certain species manage to survive in an urban environment while others do not. The book cites one example—the Rothamsted insect survey—and analyzes the pressures of development in the surrounding land area. One paper addresses the educational and esthetic value of an insect-plant relationship in an ever expanding development of urban spaces. Another paper shows the value and benefit of a scientific investment in urban agriculture—defined as small-scale agriculture in urban areas—as contributing to food crops. Some papers also examine the use of insecticides and technology transfer in the management of urban pest control. This book will be valuable for entomologists, urban planners and developers, environmentalists, and for general readers residing in metropolitan areas.

  • Dynamics of Development: Experiments and Inferences

    Selected Papers on Developmental Biology
    • 1st Edition
    • Paul A. Weiss
    • English
    Dynamics of Development: Experiments and Inferences provides an understanding of the dynamic order of living systems. This book presents a methodical approach to the unrestricted exploration of all the aspects that a living system offers, which is evaluated logically through experiment and inference. Organized into five parts encompassing 24 chapters, this book begins with an overview of the adaptive features of the nervous system. This text then examines the molecular control of cellular activity. Other chapters focus on resolving the fragments of the chemical endowment of the cell. This book discusses as well the mechanisms of respiration and photosynthesis, which have been connected with arrays of macromolecular complexes in definite sequential order. The final chapter deals with the fundamental principle of neural intercommunication. This book is a valuable resource for biochemists, biologists, zoologists, neurophysiologists, and scientists. Students and research workers interested in the dynamic order of living systems will also find this book useful.

  • Avian Biology

    Volume II
    • 1st Edition
    • Donald S. Farner + 1 more
    • English
    Avian Biology, Volume II is a collection of papers that deals with the biology of birds such as their integumentary and respiratory systems. One paper describes the integument of birds that includes the skin, feathers, pterylosis, skin muscles, and other integumentary derivatives such as beaks, comb, claws, and spurs. The book explains the process of molting and the different generations of feathers; such molting is dependent on the wear and tear of the plumage, as well as hormonal changes. One author compares the blood vascular system of birds and mammals, and then gives a detailed description of avian hematology. Other papers deal with the respiratory functions, digestive system, and the nutritional needs of birds. Of interest is one author's description of the production of nutritive fluids, holocrine, which is secreted for the young. This secreted fluid contains about 23 percent protein, 10 percent fat, and no sugar. Unlike mammalian milk, it also contains cells. Another paper examines the intermediary metabolism of birds and the climatic effects on metabolism. This book is suitable for bird enthusiasts, zoologists, and avian biologists.

  • Measles Virus and Its Biology

    • 1st Edition
    • K. B. Fraser + 1 more
    • T. W. Tinsley + 1 more
    • English
    Measles Virus and Its Biology deals with the biological and clinical problems of the viral disease, measles. This book also describes the behavior of the measles virus in terms of its immunological, biochemical, or molecular-biological aspects. The authors review the epidemiology and pathogenesis of measles and discuss how the virus flourishes and mobilizes in the human body through a close association with leukocytes and lymphoid organs. Biological characters and genetic markers of the virus can serve to separate different isolates of the measles virus from one another. Radioactive labeling techniques have detected six structural proteins associated with the virus; a schematic diagram in the book shows the structural components and the biochemical dissection of the virus. The authors also discuss that the various immune responses to the virus can be due to "variation in the patient" rather than virus mutation. The authors do not discount that the physiological behavior of the virus such as its location, number, or replication can also affect the host. This text is suitable for the clinical research workers dealing with immunology, infectious diseases, cellular chemistry, or molecular biology.

  • Wild Animals in Captivity

    • 1st Edition
    • H. Hediger
    • English
    Wild Animals in Captivity covers some of the mistaken notions concerning the conditions of animals in captivity, most of which are the result of an anthropomorphic approach to the subject. This book is composed of 12 chapters and starts with an overview of the historical development of zoological gardens. The succeeding chapters deal with the territorial requirements and sociological factors in the wild life. These topics are followed by discussions of the wild animal’s transition behavior from freedom to captivity; the physiological and psychological aspects of animal captivity; and the motive and situation of animal escapes. Other chapters emphasize the physical and biological environment of animals in captivity. The final chapters examine the problems related to feeding patterns, and nutrition of captive animals. These chapters also explore the relationship between human and animal, their capacity to be tamed and trained. This book will prove useful to zoologists.

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