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Elsevier

Books in Life sciences

  • Hyperspectral Imaging

    • 2nd Edition
    • Jose Manuel Amigo + 1 more
    • English
    Hyperspectral Imaging, Second Edition builds on the foundational insights of the first edition, covering core analytical frameworks and introducing new algorithms, hardware technologies, and cutting-edge applications. By incorporating the latest research findings and case studies, sections provide readers with enhanced tools and techniques for effective hyperspectral and multispectral image analysis across diverse scientific, industrial, and field domains. The book also addresses evolving challenges and fresh opportunities in the field, ensuring that users are equipped with the most current knowledge and practices. It underscores the continued relevance and transformative potential of hyperspectral and multispectral imaging in contemporary research and industry.Graduate students, academics, early researchers, and industry scientists across various disciplines working with hyperspectral and multispectral images, including analytical chemistry, remote sensing, vegetation and crops, food and feed production, forensic sciences, biochemistry, medical imaging, pharmaceutical production, art studies, cultural heritage, and more will find this update extremely useful.

  • Responsible AI in Healthcare

    Navigating the EU AI Act and Global Regulatory Frameworks
    • 1st Edition
    • Miltiadis D. Lytras + 3 more
    • English
    Responsible AI in Healthcare: Navigating the EU AI Act and Global Regulatory Frameworks examines how health systems design, deploy, and oversee AI under evolving legal and ethical mandates. It provides an integrated, practice‑oriented roadmap for compliance and responsible innovation. This book offers the first integrated, comparative treatment of the EU AI Act and global regulatory frameworks for healthcare, translating ethics and law into operational evaluation, governance, and value assessment. Through structured cases, decision tools, and stakeholder methods, it equips researchers and clinicians to design, validate, and deploy AI responsibly—and to keep learning as regulations evolve. Readers gain actionable tools, checklists, and frameworks to operationalize ethical AI, prepare for audits and certifications, and anticipate global convergence (“Brussels Effect”) shaping digital health. The volume serves clinicians, administrators, developers, policy and legal experts seeking rigorous yet accessible guidance.

  • Smart Coldwater Precision Aquaculture

    AI and Eco-Friendly Strategies for Fish Health
    • 1st Edition
    • S. Rehan Ahmad + 2 more
    • English
    Smart Coldwater Precision Aquaculture: AI and Eco-Friendly Strategies for Fish Health addresses the growing need for innovative solutions in coldwater aquaculture. As demand increases for species like salmon and trout, challenges such as disease management, environmental sustainability, and climate impacts require advanced, precision-based approaches. This book fills a critical gap by combining artificial intelligence with eco-friendly practices tailored specifically for coldwater environments. The contents cover foundational concepts of precision aquaculture and AI integration, followed by detailed chapters on machine learning applications, big data analytics, IoT sensors, and green nanotechnology. Sustainable strategies including probiotics, phytochemicals, and integrated multi-trophic aquaculture are explored. The volume also examines translational applications such as climate resilience, blockchain for data security, and policy frameworks. The comprehensive table of contents reflects a multidisciplinary approach involving global experts. Smart Precision Aquaculture benefits researchers, fish health specialists, technology developers, and managers by providing actionable guidance on AI-powered fish health management and sustainable farming. It equips professionals with cutting-edge knowledge to enhance productivity while minimizing environmental impacts. This reference supports the advancement of coldwater aquaculture toward a resilient and responsible future.

  • Sustainable Soil Management

    Bridging the Sustainable Development Goals
    • 1st Edition
    • Owais Bashir + 4 more
    • English
    Sustainable Soil Management: Bridging the Sustainable Development Goals addresses the issue of sustainable soil management and its connection to achieving Sustainable Development Goals (SDGs). It presents a range of strategies, policies, and implementation approaches for sustainable soil management, drawing on examples from around the world. In addition to sustainable soil management practices, the book also covers the dynamics of soil health, the role of soil organic matter, and the integration of agroecology and biodiversity in enhancing food security and environmental sustainability.By examining the interconnectedness of soil with key SDGs—such as zero hunger, clean water, and climate action—this book provides a roadmap for addressing global challenges.

  • Novel Uses of Mushrooms in Foods and Nutraceuticals

    • 1st Edition
    • Yugal Kishore Mohanta + 3 more
    • English
    In an era where sustainable agriculture and health-promoting foods are more vital than ever, Novel Uses of Mushrooms in Foods and Nutraceuticals explores the diverse potential of mushrooms as a cornerstone of future food systems. Covering a broad spectrum of innovations, including advanced cultivation techniques, molecular breeding, and nanotechnology aimed at maximizing mushroom productivity and product diversity, this book analyzes the classification, taxonomy, and biological properties of edible and medicinal mushrooms, providing essential knowledge for researchers and industry professionals seeking to develop high-value functional foods and nutraceuticals. Highlighting recent breakthroughs, Novel Uses of Mushrooms in Foods and Nutraceuticals examines the application of mushroom-derived proteins, bioactive compounds, and natural pigments in health, cosmetics, and industrial sectors. It explores mushroom-derived pre- and probiotics and their impact on the gut microbiota and emphasizes the role of mushrooms in sustainable practices such as bioremediation, circular economy, and biodegradable packaging. With insights into policy, global trade, and future trends, this volume equips readers to drive innovation and sustainable growth in the mushroom industry.

  • Health Geography

    Theories, Methods, and Case Studies
    • 1st Edition
    • Peng Jia
    • English
    Health Geography: Theories, Methods, and Case Studies examines the interdisciplinary domain of health geography, systematically integrating geographical science with public health paradigms. The book provides an in-depth analysis of the theoretical foundations, methodological innovations, and practical implications of health geography. Special emphasis is placed on employing geo-spatial technologies, such as Geographic Information Systems (GIS) and remote sensing to enhance disease prevention, health risk assessments, and healthcare resource allocation.By fostering an integrative dialogue among geography, epidemiology, and advanced technological approaches, the book addresses contemporary public health challenges from local to global scales. The book includes over 50 international case studies addressing infectious and chronic diseases, and health resource allocation.

  • Gut Health in Diabetes and Gastrointestinal Wellness

    Mechanisms and Clinical Applications
    • 1st Edition
    • Sushil Kumar Dubey + 2 more
    • English
    Gut Health in Diabetes and Gastrointestinal Wellness delves into the intricate relationship between gut microbiota and diabetes, emphasizing their significant impact on gastrointestinal health. This book bridges the gap between cutting-edge research and practical applications, offering a comprehensive exploration on how the gut microbiome affects both metabolic and gastrointestinal health. By examining current scientific findings, the book elucidates the mechanisms through which gut bacteria impact insulin sensitivity, glucose metabolism, and inflammatory responses. Additionally, practical strategies for optimizing gut health are provided, encompassing dietary recommendations, lifestyle modifications, and targeted interventions.The gut microbiome plays a crucial role in metabolic and gastrointestinal functions, and recent research has illuminated the mechanisms by which gut bacteria influence conditions such as diabetes, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). Dysbiosis, or the imbalance of gut microorganisms, can disrupt glucose metabolism, lead to insulin insensitivity, and promote chronic inflammation, all of which contribute to the progression and development of metabolic diseases like diabetes. Furthermore, gut dysbiosis is linked to various gastrointestinal disorders, often worsening symptoms and complicating treatment efforts.

  • Glial Mechanisms in Sleep and Circadian Biology

    • 1st Edition
    • Marcos G. Frank
    • English
    Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep.Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

  • Oilseeds and Fats

    Trait Improvement, Processing, Properties and Applications
    • 1st Edition
    • Sanju Bala Dhull + 2 more
    • English
    Oilseeds and Fats: Trait Improvement, Processing, Properties and Applications covers recent developments in the areas of oilseeds production practices, breeding, and genetic improvement for sustainable production, with an emphasis on processing technologies and nutrition. The book explores eco-friendly extraction methods, waste reduction techniques, and the potential of using waste by-products for energy production or other applications. Specific sections deal with production, breeding, processing methods, composition, and consumption trends, and then delve into oilseeds and fats origin, composition, and characteristics, as well as the principles and methods involved in processing and refining these resources.Additional sections cover oilseed crops processing, properties, and application, offering insights into the utilization of oilseeds and fats to develop new products that meet consumers' evolving preferences, thus addressing environmental concerns. With increasing awareness of environmental issues and climate change, the book underscores the significance of sustainable practices in the oilseed and fats industry.

  • Artificial Intelligence (AI) in Cancer Biology

    Advancements in Diagnosis and Treatment
    • 1st Edition
    • Sadhna Aggarwal
    • English
    Artificial Intelligence (AI) in Cancer Biology: Advancements in Diagnosis and Treatment explores the revolutionary impact of AI on cancer biology and oncology. This comprehensive volume delves into AI technologies, including machine learning and deep learning, enhancing our ability to understand, diagnose, and treat cancer with unprecedented precision. The book covers a wide range of topics, from cancer biology fundamentals to AI-driven techniques in diagnosis and personalised treatment. It discusses medical imaging, genomics, drug discovery, and predictive modelling, along with ethical and regulatory considerations, offering a holistic view of AI in cancer research. For academic audiences, this book provides invaluable insights into improving clinical outcomes and patient care. Researchers and clinicians will benefit from the detailed analysis of AI applications, while students and scholars will find a wealth of information to support their studies and future innovations in cancer treatment.

  • Nutritional Epigenetics

    Food-Derived microRNAs in Health and Disease
    • 1st Edition
    • Shariful Islam + 3 more
    • English
    Nutritional Epigenetics: Food-Derived microRNAs in Health and Disease offers perspective on the role of dietary microRNAs as pivotal epigenetic regulators influencing health trajectories and disease susceptibility. The book brings together current research on the bioavailability and molecular mechanisms by which plant and food-derived microRNAs modulate gene expression, including their crosstalk with DNA methylation, histone modifications, and gut microbiota. Detailed food-specific chapters examine the epigenetic impact of key dietary sources such as Brassicaceae (crucifers), rice, milk, and fermented products, highlighting their transgenerational and life-stage effects. Practical insights into food processing, culinary traditions, and the design of microRNA-fortified products bridge the gap between bench science and real-world applications. Nutritional Epigenetics equips researchers, clinicians, and industry innovators with a resource that advances the understanding of microRNA-mediated nutritional epigenomics, while guiding the development and safety assessment of microRNA-enhanced functional foods. By integrating molecular biology with population-level evidence and translational strategies, this text fosters the development of novel dietary interventions aimed at optimizing health across the lifespan and mitigating chronic disease risk.

  • Heavy Metals in Food and Food Systems

    Assessment, Risks, Regulations, and Sustainable Mitigation Strategies
    • 1st Edition
    • Matthew Chidozie Ogwu + 1 more
    • English
    Heavy Metals in Food and Food Systems: Assessment, Risks, Regulations, and Sustainable Mitigation Strategies offers a timely, authoritative examination of how toxic metals enter the food chain, the risks they pose, and strategies to reduce exposure. With increasing environmental contamination, understanding pathways from soil, water, and air to food products is essential. This book provides tools for assessing contamination, navigating regulatory standards, and implementing mitigation measures to protect public health and ensure food safety globally. The content is organized into four parts: sources and pathways of heavy metal contamination; transfer during agricultural practices and food processing; detection methods and risk assessment; and governance, mitigation, and future challenges. It covers contamination sources, analytical techniques, exposure risks, and international regulations. Real-world case studies and innovations highlight practical solutions for reducing heavy metal risks across the food system. This book is an essential resource for researchers, faculty, and industry professionals in food science, toxicology, environmental health, and policy. It supports graduate education and helps policymakers develop effective strategies to safeguard food supplies and promote sustainable practices worldwide.

  • Biomarkers in Neurological Disorders and Treatment

    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Decoding the Brain: Biomarkers in Neurological Disorders and Treatment provides a comprehensive exploration of the latest advances in neurological biomarkers, detailing their discovery, validation, and application in clinical practice. By offering insights into the biological underpinnings of various neurological disorders, this book aims to bridge the gap between cutting-edge biomarker research and its practical implementation in patient care.

  • Fruit and Vegetable Nutrition

    Practical Applications for Improving Human Health
    • 1st Edition
    • Yang Shan + 3 more
    • English
    Fruit and Vegetable Nutrition: Practical Applications for Improving Human Health provides insights into the nutritional benefits of fruits and vegetables, their role in human health, and practical applications for functional food innovation. Sections explore how certain fruits and vegetables such as berries, citrus, and nightshades can benefit chronic conditions such as cardiovascular disease, obesity, and diabetes while also linking diet to improved health outcomes. The book also addresses the role of fruits and vegetables and their vital bioactive compounds in the development of functional foods and nutraceuticals, offering insights for professionals who aim to create health-promoting products.In addition, sections discuss how certain processing techniques can retain essential nutrients and improve food product quality and how specific combinations of fruits and vegetables can promote the growth of key gut bacteria, improving health status, inflammation, and the gut microbiome. The book concludes with the role of smart equipment in the fruit and vegetable industry to streamline quality and improve nutritional outcomes and how biosynthesis technology can offer advantages in the production of fruits and vegetables, thus contributing to sustainable practices.

  • Contaminants in Aquaculture

    Safeguarding Blue Foods for a Sustainable Future
    • 1st Edition
    • Amit Kumar + 1 more
    • English
    Contaminants in Aquaculture: Safeguarding Blue Foods for a Sustainable Future addresses critical challenges posed by chemical, biological, and emerging pollutants in aquaculture systems. As aquaculture becomes the fastest-growing global food production sector, contamination risks threaten seafood safety, ecosystem health, and public trust. This reference consolidates fragmented knowledge to support sustainable blue food production and safeguard public health. The book covers heavy metals, pesticides, antibiotics, microplastics, petroleum hydrocarbons, biotoxins, nanomaterials, and emerging contaminants, exploring their environmental pathways, bioaccumulation, toxicodynamics, and regulatory challenges. It integrates advanced detection technologies, risk modeling, and mitigation strategies, supported by case studies and AI-enabled monitoring tools. The book also examines global policy frameworks and the integration of blue economy principles for contaminant control. Contaminants in Aquaculture: Safeguarding Blue Foods for a Sustainable Future benefits researchers, regulators, and industry professionals by providing a unified, evidence-based foundation to assess risks, design regulatory standards, and implement sustainable aquaculture practices. By bridging science, policy, and practice, this reference enhances seafood safety, ecosystem resilience, and global blue food sustainability for current and future generations.

  • Rhythmic Regulation in Neuroscience and Clinical Practice

    • 1st Edition
    • Barbara Minton + 2 more
    • English
    Rhythmic Regulation in Neuroscience and Clinical Practice covers cutting-edge and up-to-date information on currently available rhythm-related treatment procedures, as well as the interplay between music and cognition. The book contains contributions from leading experts in the across several fields, exploring the ways in which rhythmic stimulation serves as a powerful neuromodulator, enhancing cognitive function and promoting healing. Best suited for clinicians and researchers interested in neuromodulation, this volume offers profound insights into how rhythm shapes our cognition, influences our well-being, and paves the way for innovative therapeutic practices.

  • Medicinal and Aromatic Plants in the Post-Genomics Era

    • 1st Edition
    • Rhydum Sharma + 2 more
    • English
    Medicinal and Aromatic Plants in the Post-Genomics Era brings together current research on species long valued for their therapeutic and industrial properties, now drawing renewed interest from the pharmaceutical, nutraceutical, cosmetic, and agricultural sectors amid rising demand for natural alternatives to synthetic chemistry.At the core of this shift is a deeper molecular understanding of how these plants produce their bioactive constituents. Genomics, transcriptomics, proteomics, and metabolomics have exposed the genetic architecture and biochemical pathways behind secondary metabolite synthesis, while computational biology helps make sense of the resulting complexity. Together, these tools are speeding up compound discovery and clarifying how such molecules function biologically.The chapters that follow turn this knowledge into practice: systems biology and metabolic engineering for boosting yields, CRISPR-based genome editing for reprogramming pathways, synthetic biology and AI-driven modeling for predicting and designing new biosynthetic routes, and emerging production platforms — from hairy root cultures to inducible expression systems — for expanding output sustainably.Taken together, the volume traces a progressive arc: from reading a plant's genetic blueprint to realizing its potential as a source of usable, real-world solutions in the clinic, the field, and the marketplace, offering a practical reference for both researchers and industry practitioners working at the intersection of plant biology and biotechnology.

  • The Role of Machine Learning and Artificial Intelligence in Revolutionizing Healthcare

    • 1st Edition
    • Prashant Kesharwani + 1 more
    • English
    Revolutionizing Healthcare: The Role of Machine Learning and Artificial Intelligence describes the complexity of healthcare data that necessitates the expanding use of artificial intelligence (AI). This book offers an explicit accounting of vital aspects on artificial intelligence in healthcare, discussing perspectives of the technologies explored based on findings outlined in highly organized tables, illustrative figures, and flow charts. It brings together novel applications of artificial intelligence in healthcare and helps readers define major gaps in knowledge that can lead to significant scientific discoveries.In addition, the book covers computational drug design, genomic data mining, nanomedicines, medical devices, cosmeceuticals, biosensors, genome counseling, quality control, clinical trials, and cybersecurity. Researchers, students, and scientists will find the book provides foundational and practical knowledge, along with the most advanced AI applications in healthcare.

  • Prof. of Drug Substances, Excipients and Related Methodology

    • 1st Edition
    • Volume 52
    • English
    Physical and chemical data, synthesis or degradation pathways, various analytical techniques for identification and quantification, multiple separation methods, and the pharmacology of drug substances are essential at all stages of pharmaceutical development and are invaluable to practitioners; however, they are scattered throughout the scientific literature. The Analytical Profiles of Drug Substances and Excipients compiles this information into a singular source. No other book series delivers this crucial information as swiftly and relevantly. The Profiles series comprises review articles and database compilations organized into five principal categories: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology for the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis. The 52nd volume of Profiles of Drug Substances, Excipients, and Related Methodology offers detailed profiles of five pharmaceutical compounds: Pazopanib, Fenofibrate, Sumatriptan, Beclomethasone dipropionate, and Ceftaroline fosamil. This volume contains a review article on Stimuli-Responsive Polymers, detailing their types, classification, and applications in drug delivery.

  • Advances in Agronomy

    • 1st Edition
    • Volume 201
    • English
    Advances in Agronomy, Volume 201, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Genetic Advances in Inborn Errors of Immunity

    • 1st Edition
    • Volume 117
    • English
    Genetic Advances in Inborn Errors of Immunity, published as Volume 117 of the serial Advances in Genetics, provides a comprehensive and up‑to‑date overview of the rapidly evolving genetic landscape underlying inborn errors of immunity (IEI). Bringing together authoritative contributions from leading experts, this volume examines how advances in genomics, molecular diagnostics, and functional immunology have transformed the understanding, classification, and clinical management of primary immunodeficiency disorders. The chapters span severe monogenic conditions to complex, polygenic phenotypes, highlighting both mechanistic insights and translational implications. Collectively, the volume serves as an essential reference for researchers and clinicians seeking to understand how genetic discoveries are reshaping immunology and precision medicine.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 136
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Integrating Artificial Intelligence with Virtual Screening

    A New Era in Drug Discovery
    • 1st Edition
    • Vivek Asati + 1 more
    • English
    Integrating Artificial Intelligence with Virtual Screening: A New Era in Drug Discovery addresses the evolving landscape of drug discovery by combining traditional virtual screening with cutting-edge artificial intelligence technologies. This volume offers an interdisciplinary guide to AI-driven ligand and structure-based screening methods, including machine learning, deep learning, and generative models, thus enabling faster and more accurate identification of drug candidates. It covers mathematical models, computational workflows, and optimization strategies such as Pareto-based and physics-based approaches.Sections also discuss challenges in navigating ultra-large chemical libraries and present practical case studies that demonstrate real-world applications. Edited by leading researchers, the book provides authoritative insights suited for graduate students, researchers, and industry professionals. Users will be empowered by the latest tools and knowledge to innovate drug discovery pipelines and support the development of precision medicines and foster advancements in pharmaceutical sciences.

  • Essentials of Stem Cell Biology

    • 4th Edition
    • Robert Lanza + 1 more
    • English
    Essentials of Stem Cell Biology, Fourth Edition is designed for the growing community of scientists, researchers, practitioners, and students embracing the latest advancements in stem cells. This comprehensive book, a collaboration of 7 editors and over 200 pioneering scholars and scientists, provides a thorough understanding of adult and embryonic stem cells. It combines fundamental concepts with cutting-edge research in specific organ systems, ensuring a robust foundation for anyone entering the field. Beyond the basics, the book delves into early development and the differentiation of ectoderm, mesoderm, and endoderm.It covers methods, applications to human diseases, regulation, ethics, and patient perspectives, leaving no stone unturned in the stem cell domain.

  • Empowering Health through Lifestyle Medicine

    The Essential Guide for Preventing and Managing Chronic Disease
    • 1st Edition
    • John Anthony Stevens
    • English
    The global rise in lifestyle-related illness is one of the most complex problems facing humanity. Feeling disempowered? Lifestyle Medicine is a powerful solution.Empowering Health through Lifestyle Medicine: The Essential Guide for Preventing and Managing Chronic Disease is an essential, evidenced-based resource for use by anyone with a stake in healthcare. This book is for clinicians, public health advocates, ecologists, policy makers, academics, teachers and for those researching illness prevention, chronic disease management and reversal. This book will deliver the knowledge, skills, tools and procedures to implement Lifestyle Medicine in practice. Lifestyle Medicine’s 6 pillar framework of nutrition, physical activity, sleep, stress, substance misuse management and connection is the best lens we have to see the way forward in preventing and managing the rampaging growth in lifestyle-related illness.

  • Morbidity Prevention in Aging

    The Role of Salutogenesis Amidst Crises
    • 1st Edition
    • Nestor Asiamah + 3 more
    • English
    Morbidity Prevention in Aging: The Role of Salutogenesis Amidst Crises addresses the urgent need to rethink disease prevention strategies for an aging population. The book begins by exploring how age-friendly environments support health-seeking behaviors. The next section focuses on developing personal skills such as resilience and self-efficacy for maintaining health during crises. Section III examines the reorientation of health services to support preventive care, including community care and diet promotion, while Section IV addresses the creation of policies that facilitate health-promoting interventions and integrate prevention strategies. Community engagement and empowerment in promoting health is emphasized in the fifth section.The book concludes by providing a framework for understanding disease prevention amidst crises, focusing on diverse racial, cultural, and socioeconomic experiences and ensuring equitable opportunities for lifelong disease prevention. This groundbreaking book emphasizes a salutogenic approach that focuses on factors promoting health rather than merely treating diseases. It provides a comprehensive framework for understanding how to maintain health and prevent diseases across the lifespan, even amidst challenges such as wars, climate change, and industrial hazards.

  • Protein Folding

    • 1st Edition
    • Timir Tripathi
    • English
    Protein Folding explores the fundamental and applied aspects of protein folding, misfolding, and stability in biological systems. Focusing on the biochemical principles and molecular dynamics that drive folding processes, the book provides readers with a comprehensive understanding of how proteins attain their native structures and what happens when this process goes awry. Covering diverse approaches from structural biology, biophysics, enzymology, and systems biology, the book highlights the molecular basis of folding pathways and the pathological consequences of misfolded proteins in diseases such as Alzheimer's, Parkinson's, and cystic fibrosis. It integrates insights into chaperone function, folding kinetics, and the cellular quality control mechanisms that safeguard proteostasis. Across its chapters, the book addresses key themes including protein folding landscapes, folding intermediates, the role of cellular compartments, aggregation-prone sequences, and the impact of mutations. It also examines current methodologies for studying protein folding, including spectroscopy, calorimetry, and computational simulations, and considers emerging therapeutic strategies that target misfolding and aggregation. This book is a valuable resource for biochemists, molecular biologists, biotechnologists, enzymologists, and researchers in protein science. It supports academic researchers, postgraduate students, and pharmaceutical scientists working to understand protein behavior and develop interventions for protein misfolding diseases.

  • Nanomedicine for Neurological Disorders

    Design, Delivery, and Clinical Perspectives
    • 1st Edition
    • Malik Zainul Abdin + 4 more
    • English
    Nanomedicine for Neurological Disorders: Design, Delivery, and Clinical Perspectives addresses the urgent need for innovative solutions in treating complex neurological and neurodegenerative diseases. As the global burden of conditions such as Alzheimer's, Parkinson's, multiple sclerosis, and brain tumors continues to rise, the scientific community faces the critical challenge of safely and effectively delivering therapeutics across the blood-brain barrier. This reference meets the needs of neuroscientists, clinicians, pharmaceutical scientists, and biomedical engineers seeking advanced strategies and translational insights in neuro-nanomedicine. The contents are structured to provide a comprehensive, interdisciplinary exploration of the field. Chapters cover the anatomy and connectivity of the human brain, the global burden and mechanisms of neurological disorders, conventional and nanomedicine-based drug delivery systems, and the intricacies of the blood-brain barrier. Readers will benefit from detailed analyses of nanocarrier engineering, stability, analytical techniques, toxicological safety, regulatory challenges, and artificial intelligence-driven drug design. Real-world case studies, clinical trial data, and future outlooks are presented alongside ethical and patient-centric considerations, ensuring a holistic perspective on the evolving landscape of neuro-nanomedicine. Nanomedicine for Neurological Disorders delivers essential benefits by bridging the gap between laboratory innovation and clinical practice. It equips readers with practical knowledge, foundational advances, and visionary insights to inspire new research directions, inform better decision-making, and accelerate the development of safer, more precise treatments for brain-related disorders. This reference is an indispensable resource for researchers, clinicians, and innovators at the forefront of neurological therapeutics.

  • Engelking's Textbook of Veterinary Physiological Chemistry

    • 4th Edition
    • Kevin M. Connolly
    • English
    Bridging the gap between basic and clinical science concepts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this updated text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding.With numerous illustrations and both instructor and student companion websites with updated PowerPoint images, lecture slides, and Snapcasts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and updated case studies extend the breadth and depth of learning resources.

  • Complications in Neuroanesthesia

    • 2nd Edition
    • Hemanshu Prabhakar
    • English
    Complications in Neuroanesthesia, Second Edition offers an extensive examination of the complications associated with neuroanesthesia practice, emphasizing both new and existing challenges in the field. This updated edition introduces critical topics such as locked-in syndrome, cerebellar mutism syndrome, delirium, awareness, memory loss, perioperative stroke, and coma, alongside established complications like brain herniation, hydrocephalus, and seizures. Each complication is meticulously examined in separate chapters, detailing the pathophysiology, mechanisms, diagnosis, treatment, and prevention strategies. This book also addresses cardiovascular issues, including stunned myocardium, as well as fluid and electrolyte disturbances like glucose dysregulation and conditions like post-dural puncture headache, malignant hyperthermia and reperfusion injury. Written in an accessible format for quick navigation, this resource provides invaluable insights into the perioperative management of neurosurgical and neurologic patients. This book is a practical tool for trainees, clinicians, and researchers in anesthesia, neuroanesthesia, neurosurgery, neurocritical care, and neurology. By highlighting preventable mishaps, this edition aims to enhance the safety and efficacy of neuroanesthesia and neurocritical care practice.

  • PACAP

    From Discovery to Function
    • 1st Edition
    • David Vaudry + 1 more
    • English
    PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part D
    • 1st Edition
    • Volume 305
    • English
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Methods in Systems Bioinorganic Chemistry

    • 1st Edition
    • Volume 741
    • English
    Methods in Systems Bioinorganic Chemistry, Volume 741 provides understanding of high-level properties involving metals in biology that are founded on molecular or mechanistic level interactions. Currently, there is no established “tool kit” for studying bioinorganic systems, so the methods included in the book span a diverse range of topics and approaches, from imaging to proteomics, from metals-in-mice to mathematical modeling. Specific chapters cover Inductively Coupled Plasma Mass Spectrometry (ICP-MS)-based methods to quantify transition metals in cells and vertebrate models, ICP-MS elemental analysis in tissue samples, and much more.Additional chapters delve into An inductively-coupled-... triple quadrupole method with oxygen for the determination of essential elements and protein concentration, Calculating metal speciation of proteins inside cells, Probing biological copper in the subfemtomolar regime, Using LC-ICP-MS chromatography to detect and characterize Labile Metal Pools, Linking dynamic bioinorganic chemistry processes of toxic metals in the bloodstream to establish their exposure-response relationship in humans, Contextualizing X-ray fluorescent microscopy – high resolution X-rays meet subcellular morphology, Chemoproteomic profiling of transition metal binding sites in bacterial proteomes, Heme Labeling by Proximity (HeLP) to Identify Hemoproteins, and much more.

  • Enzymology in Drug Discovery

    • 1st Edition
    • Volume 740
    • English
    This volume is focused on the application of enzymology to drug discovery, with the overarching objective of introducing the general audience to the important role that enzymology plays in modern, molecular targeted drug discovery. The volume opens with a chapter on the role of enzymes in normal human physiology and the causal role played by aberrant enzyme activity in various disease state. A second chapter provides a comprehensive review of inhibition modalities for therapeutic enzyme inhibitors. From there the volume is composed of chapters that cover two general categories of information: (1) methodologies for studying enzyme-ligand interactions and (2) case studies of molecular targeted drug discovery against specific enzyme targets. Chapters within the first category cover methods such as assay design, the role of structural biology in drug optimization, analysis of slow and tight binding inhibitors, enzyme-inhibitor complex dynamics, and covalent enzyme inactivators. The second category includes case studies of therapeutic inhibitors of various enzyme target classes: proteases, methyltransferases, histone demethylases, helicases, nucleic acid processing enzymes, kinesin motor proteins, and cytochrome P450s. Finally, a chapter is also devoted to therapeutic replacement or repair of defective enzymes.

  • Blockchain-Enabled Innovations in Location-Based Services for Healthcare

    • 1st Edition
    • Ajay Kumar Gupta + 3 more
    • English
    Blockchain-Enabled Innovations in Location-Based Services for Healthcare addresses the growing need for secure, intelligent healthcare solutions integrating location-based services (LBS), Internet of Things (IoT), and blockchain technologies. This reference explores how these technologies transform healthcare delivery improving autonomy and real-time care while safeguarding sensitive data. It responds to the challenges posed by the proliferation of wearable sensors and smart medical devices by proposing decentralized, privacy-preserving frameworks.The book’s comprehensive chapters cover blockchain trust models, adaptive privacy for patient trajectories, wearable computing, deep learning for medical imaging, secure communication in healthcare IoT, and AI-powered diagnostics. Contributions from global experts provide case-driven analyses and technical depth, addressing current challenges in healthcare data security, interoperability, and predictive modeling. The interdisciplinary approach integrates computer science, data privacy, and healthcare informatics, making it a valuable resource for researchers and professionals.Blockc... Innovations in Location-Based Services for Healthcare benefits academic researchers, industry practitioners, graduate students, and policymakers by offering cutting-edge knowledge in secure, decentralized healthcare systems. It equips readers with advanced methodologies and practical solutions to design inclusive healthcare technologies, fostering innovation in smart health monitoring, medical image analysis, and data-driven diagnostics within privacy-compliant frameworks.

  • Motor Control Methods and Clinical Applications

    • 1st Edition
    • Volume 220
    • Robert Chen + 1 more
    • English
    Motor Control Methods and Clinical Applications provides a detailed review on the use of non-invasive brain stimulation to study motor control. Split into two distinct parts, this new volume covers the latest research in motor control, including real examples of these methods in a clinical setting. The first part covers advanced methods such as transcranial magnetic, electrical and ultrasound stimulation, long latency, spinal reflexes, multichannel EMG, and EEG-EMG analyses that can be used to examine and modulate the motor system. The second part of the book addresses the clinical applications of these methods.

  • Model Validation and Uncertainty Quantification in Biomechanics

    From Soft Biological Tissue to Blood Flow
    • 1st Edition
    • Gerhard A. Holzapfel + 2 more
    • English
    Model Validation and Uncertainty Quantification in Biomechanics: From Soft Biological Tissue to Blood Flow provides a comprehensive overview of the latest technology in biomechanical modeling and analysis. Part I presents the foundational principles of modeling primary biomechanical systems, including the intricate workings of the cardiovascular system. This section also provides invaluable insights into essential topics such as sensitivity analysis, uncertainty quantification, machine learning, and surrogate modeling. In Part 2, the book transitions into an in-depth examination of the current state-of-the-art in model validation techniques across a diverse array of biomechanical disciplines, including the latest advancements and best practices. Part 3 introduces current and innovative approaches for quantifying uncertainties inherent in biomechanical modeling. Chapters range from established methodologies to emerging techniques, providing a comprehensive overview of the various strategies employed in addressing uncertainty in biomechanical studies. Finally, in Part 4, the book concludes with a focus on cutting-edge methods, specifically spotlighting the utilization of machine learning and surrogate modeling for both model validation and uncertainty quantification. Through real-world applications and case studies, this book provides an in-depth understanding of how these advanced techniques are reshaping the landscape of biomechanics research.

  • The Analytical Chemistry of Cannabis

    Chemistry, Pharmacology, Manufacturing, Use, and Control of Medicinal Cannabis and Cannabinoid Dosage Formulations
    • 2nd Edition
    • Brian F. Thomas + 2 more
    • English
    The Analytical Chemistry of Cannabis: Chemistry, Pharmacology, Manufacturing, Use, and Control of Medicinal Cannabis and Cannabinoid Dosage Formulations: Second Edition presents advanced methods in analytical chemistry to address modern issues surrounding cannabis-based products. Since the first edition, the cannabis industry has rapidly expanded its array of recreational and medicinal products. This volume provides crucial methods to support the manufacturing, labeling, and distribution of safe, consistent products with known chemical content and performance. It offers updated information on the chemistry and pharmacology of cannabis and cannabinoids and aims to resolve industry challenges by fostering understanding among scientists, public health officials, and non-scientist stakeholders.The book is valuable for professionals in analytical chemistry, pharmacology, medicine, and law enforcement, as well as for advanced academic courses in related fields.

  • Technology-Assisted Physical Gait Rehabilitation

    How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy
    • 1st Edition
    • Tomislav Baček + 3 more
    • English
    Technology-Assisted Physical Gait Rehabilitation: How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy explores computational modeling techniques, robotic assistance, data science, and other technological tools and how they can be jointly used in driving and guiding physical gait therapy in impairments such as stroke, traumatic brain injury, and incomplete spinal cord injury. This book gathers experts in robotics, human biomechanics, physical therapy, neuroscience, engineering, and medicine, presenting their ongoing work and discussing their views on the future direction of technology-assisted gait therapy. It showcases the latest advancements in the interdisciplinary and multidisciplinary field of technology-assisted gait therapy and strives to outline the developments in the coming years that are needed/likely to make the next big breakthrough in the field.

  • Model Validation and Uncertainty Quantification in Biomechanics

    Sources and Methods of Uncertainty and Variability Analysis - Volume 2
    • 1st Edition
    • Gerhard A. Holzapfel + 2 more
    • English
    Model Validation and Uncertainty Quantification in Biomechanics: Sources and Methods of Uncertainty and Variability Analysis addresses the increasing need to incorporate uncertainty and variability into computational biomechanics. As biomechanical modeling becomes more central to clinical decision-making, deterministic approaches are no longer sufficient to describe biological complexity. This reference provides a systematic treatment of uncertainty quantification, enabling more reliable, patient-specific models in cardiovascular and soft tissue applications. The volume is structured into four main sections. It begins with probabilistic fundamentals and sensitivity analysis, establishing core principles for uncertainty-aware modeling. It then explores sources of uncertainty, including vascular modeling, imaging reconstruction, MRI, ultrasound elastography, and biological variability such as sex differences. The third section focuses on computational methods such as multi-fidelity modeling and Bayesian parameter identification. The final section presents practical applications in vascular systems, cardiac mechanics, and diagnostic techniques, emphasizing clinically relevant case studies.Model Validation and Uncertainty Quantification in Biomechanics: Sources and Methods of Uncertainty and Variability Analysis provides researchers and engineers with rigorous tools to assess model reliability and variability. By combining foundational theory with applied methodologies, it supports the development of robust, predictive biomechanical simulations, advancing translational research and precision medicine in healthcare engineering.

  • An Authoritative Guide to Chronic Pediatric Abdominal Pain

    Pathophysiology, Diagnosis and Management
    • 1st Edition
    • Miguel Saps + 1 more
    • English
    An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Informati... on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

  • Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology

    • 1st Edition
    • Swagat Kumar Das + 2 more
    • English
    Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology delves into historical perspectives, current trends, and future projections for research and development of immunological and biopharmaceutical products. Sections explore immunostimulants, natural and synthetic immunostimulants in aquaculture and animal husbandry, immunomodulators, immune boosters, pre- and probiotics in health promotion, cutting-edge immunological techniques for disease diagnosis, immunotherapy in cancer treatment, and transplantation immunology. Following chapters explore the impact on pharmaceutical biotechnology, with discussions on traditional and modern approaches in drug delivery, in silico drug delivery modeling, biocomposites and their pharmaceutical applications, recent advances in monoclonal antibodies production, vaccine development, and much more. Finally, the book covers the pivotal role of AI, machine learning, and data analytics in the clinical study of immunotherapy and pharmaceutical drugs, thus paving the way for enhanced research and development efficiency. Researchers in industry and academia alike will gain valuable insights into the novel principles behind designing and developing immunological and drug products, making this title an essential resource.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 137
    • English
    Advances in Applied Microbiology presents the latest developments and innovative research in applied microbiology, covering topics such as microbial biotechnology, environmental applications, industrial processes, and medical advancements. It offers valuable insights into the practical uses of microorganisms in solving real-world challenges, making it an essential resource for researchers, professionals, and students in microbiology and related fields.

  • Neurogynecology and Associated Neurological Disorders

    • 1st Edition
    • Vishal K. Chavda + 2 more
    • English
    Neurogynecology and Associated Neurological Disorders addresses the emerging interdisciplinary field linking neurology and gynecology, focusing on how neurological disorders impact female reproductive health throughout the lifespan. The book covers foundational neuroanatomy, hormonal influences on neurological function, and specific disorders including headaches, epilepsy, pelvic neuropathies, and mental health conditions related to reproductive stages. It includes clinical guidelines, case studies, diagnostic tools, and treatment protocols tailored to hormonal phases and life stages. The integration of neurobiological mechanisms with gynecological considerations offers readers a robust framework for interdisciplinary collaboration.Reader... will find this to be a great reference that responds to the growing clinical need for integrated understanding and management of conditions such as menstrual migraines, pregnancy-related neuropathies, and menopausal neurological changes.

  • Advanced Technologies for Disease Intervention

    Innovations Across Precision Medicine, Nutrition, and Holistic Therapies
    • 1st Edition
    • Ranbir Chander Sobti + 3 more
    • English
    Advanced Technologies for Disease Intervention: Innovations Across Precision Medicine, Nutrition and Holistic Therapies, Two Volume Set investigates current and emerging advances in disease detection, diagnosis, treatment and prevention, and how molecular medicine and biotechnology have contributed to this changing landscape. Volume One focuses on sustainable health practices through biotechnology, exploring traditional health systems, diagnostic innovations, and integrative therapies. Key topics include: the role of traditional medicine and practices in sustainable health; contemporary and emerging technologies such as aptamer diagnostics, telemedicine, nanomaterials and AI in healthcare, and much more.Volume Two then delves deeper into emerging technologies for disease intervention, focusing on drug development, delivery systems, nutrition, and natural products for health. Themes explored here include: developments and trends in drug discovery; drug repurposing; contemporary drug delivery systems; phototherapeutics; personalized drug delivery; innovations in vaccine development; the role of nutraceuticals in disease prevention; and the use of natural products and herbal interventions for sustainable health.

  • Structural and Functional Dynamics of Nontuberculous Mycobacterium Proteins

    Insights into Pathogenic Mechanisms
    • 1st Edition
    • Parissa Farnia + 3 more
    • English
    Structural and Functional Dynamics of Nontuberculous Mycobacterium Proteins: Insights into Pathogenic Mechanisms explores the structural and functional dynamics of nontuberculous mycobacterium (NTM) proteins, focusing on their roles in pathogenicity, the mechanisms underlying microbial infections, and the potential for developing targeted therapeutic strategies to combat these emerging pathogens. The book begins with a foundational overview of nontuberculous mycobacteria (NTM), distinguishing them from Mycobacterium tuberculosis, their epidemiology, clinical significance, and structural biology. It discusses key structural features of NTM proteins and advanced techniques for protein structure determination, proteomic analyses, and bioinformatics approaches.Additiona... sections investigate the pathogenic mechanisms and the complexities of the host-pathogen interaction. Concluding with insights into emerging research, interdisciplinary collaboration, future treatment, and prevention strategies, this book is a helpful resource for researchers and healthcare professionals engaged in the study of infectious diseases.

  • Cell Death Part F

    • 1st Edition
    • Volume 211
    • English
    Cell Death: Part F, Volume 211 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores Methods to Assess BAX Conformation, Activation, Translocation, and Mitochondrial Outer Membrane Permeabilization, Proximity biotin labelling identification of Bcl-2 protein interactions in live cells, Bimolecular fluorescence complementation assays for investigating Bcl-2 family protein interactions, Assessing apoptotic sensitivity in primary mouse B cells by BH3 profiling, Liposome permeabilization assays to monitor pore formation by cell death proteins, Flow Cytometry Assessment of Mitochondrial Membrane Potential, Biomass, and ROS in OXPHOS-Dependent and Glycolytic Cancer Cells during Cell Death Induction, and much more.Additional chapters cover Assessment of Viability Versus Cell Death: What is What?, Flow cytometry-based drug response profiling of primary B-precursor ALL cells in co-culture with bone marrow-derived stromal cells, An in vitro model of efferocytosis in macrophage foam cells to probe lipid-driven dysregulation of dead cell clearance, Measuring tumor cell killing using in vivo bioluminescence imaging, and more.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part C
    • 1st Edition
    • Volume 304
    • English
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health, Part B, Volume 300 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics such as Neuroscience-informe... Psychoeducation for Functional Neurological Disorder, Neuroscience-informe... Psychoeducation for Multiple Sclerosis, Neuroscience-informe... Psychoeducation for Neurodegenerative Disorders (Alz & PD) / Dementia, Neuroscience-informe... Psychoeducation for Traumatic Brain Injury, Neuroscience-informe... Psychoeducation for Epilepsy, Neuroscience-informe... Psychoeducation for Stroke, Neuroscience-informe... Psychoeducation for Movement Disorders, and much more.Additional chapters cover Neuroscience-informe... Psychoeducation for Therapy, Neuroscience-informe... Psychoeducation for Pharmacotherapy, Neuroscience-informe... Psychoeducation for Brain Stimulation, Neuroscience-informe... Psychoeducation for Cognitive Rehabilitation, Neuroscience-Informe... Psychoeducation as a Digital Neurotechnology Platform, Neuroscience-informe... Psychoeducation for Policy Making (Neurolaw), Neuroscience-informe... Psychoeducation to Promote Community Engagement, and more.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 71
    • English
    Advances in Insect Physiology, Volume 71 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Virus Infection and its Endocrinological Regulation in Infected Insects, Insect Orphan Genes: Drivers of Evolutionary Innovation and Emerging Tools for Pest Management, Molecular Siege and Surrender: Cuticle Degradation and Killing Tactics of Entomopathogenic Fungi against Insect Pests, Microbiome-disease dynamics in commercially mass reared insects, Physiological Impacts of Bee Viruses, and more.

  • Lightweight, Real-time Deep Learning Models for Healthcare Applications

    • 1st Edition
    • Tina Babu + 2 more
    • English
    Lightweight, Real-time Deep Learning Models for Healthcare Applications addresses the pressing need for deploying efficient artificial intelligence models in clinical environments constrained by limited computational resources. As AI adoption accelerates in healthcare, this reference targets the gap between advanced deep learning research and practical real-time applications, emphasizing model optimization, privacy, and regulatory compliance. The content comprehensively covers model compression techniques such as pruning, quantization, knowledge distillation, and neural architecture search, alongside federated learning frameworks and real-time inference optimization. Detailed chapters present hardware-aware strategies, security considerations, continuous learning, and regulatory validation. The book also provides extensive case studies and implementation blueprints demonstrating practical deployment on devices like Raspberry Pi, NVIDIA Jetson, and mobile health platforms. This book benefits researchers, clinicians, and healthcare technology professionals by offering practical solutions to develop, validate, and implement AI models that maintain diagnostic accuracy while meeting clinical constraints. It equips students and educators with theoretical foundations and hands-on examples to foster innovation in biomedical AI, ultimately enhancing diagnostic capabilities and patient care in diverse healthcare settings.

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