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Books in Life sciences

  • Pediatric Deep Brain Stimulation

    • 1st Edition
    • George M. Ibrahim + 1 more
    • English
    Pediatric Deep Brain Stimulation offers the first comprehensive, multi-disciplinary exploration of this rapidly advancing field, providing clinicians with an authoritative guide to the science, practice, and future of pediatric neuromodulation.Orga... into four integrated sections, the book begins with the essentials of a pediatric DBS program—including state-of-the-art imaging, peri-operative management, complication avoidance, and ethical considerations unique to the developing brain. Subsequent chapters examine the use of DBS across the spectrum of childhood movement disorders, from monogenic and acquired dystonias to non-dystonic conditions. A dedicated section addresses neuromodulation for pediatric epilepsy, with a focus on emerging technologies. The book concludes with cutting-edge applications of DBS in neurodevelopmental and neuropsychiatric disorders and a view toward the integration of neuroengineering to expand the reach and future potential of circuit-based interventions in children.Edited by a pediatric movement disorders neurologist and a pediatric functional neurosurgeon who together direct an integrative, comprehensive pediatric DBS program, this volume brings a uniquely collaborative perspective and deep clinical expertise. It is an essential resource for neurosurgeons, neurologists, epileptologists, pediatric specialists, and researchers committed to advancing care for children with severe neurological disease.

  • Advancements in Personalized Cellular Immunotherapy

    A Comprehensive Guide to Cancer Treatment
    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment is an authoritative guide that delves into the foundational principles, recent advancements, and clinical applications of this innovative treatment approach, aiming to bridge the gap between research and clinical practice. It offers a thorough analysis of the mechanisms of action, therapeutic efficacy, and safety profiles of various cellular immunotherapy modalities, enabling clinicians to make well-informed treatment decisions and optimize patient outcomes. The book promotes interdisciplinary collaboration by bringing together experts from oncology, immunology, molecular biology, and translational medicine. Through detailed case studies, clinical guidelines, and practical insights, it provides healthcare professionals with the knowledge and tools needed to effectively incorporate cellular immunotherapy into standard oncology practice. Additionally, the book addresses key challenges and future directions in the field, such as strategies to enhance treatment efficacy, overcome resistance mechanisms, and broaden the accessibility of cellular immunotherapy to more patients. Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment aims to educate and empower healthcare professionals, fostering continued innovation and collaboration to improve cancer care and patient outcomes.

  • Biosimilars and Biologics in Cancer Treatment

    An Era in Therapeutic Strategies
    • 1st Edition
    • Kuttiappan Anitha + 2 more
    • English
    Biosimilars and Biologics in Cancer Therapy: An Era in Therapeutic Strategies addresses challenges and opportunities in biosimilars and biologics, integrating the latest evidence, regulatory landscapes, economic implications, and strategies to enhance cancer management. The book aims to create an all-inclusive educational resource, bridge the gap between research and clinical practice, and inspire future research in oncology. It provides a comprehensive examination of cancer therapeutics, starting with an introduction to biologics and biosimilars, their historical development, and foundational principles. Sections explain mechanisms of action, drug development processes, regulatory landscapes, and clinical applications through case studies. Emerging therapeutic strategies, including combination therapies and personalized medicine, are also covered. This book benefits researchers, oncologists, pharmacologists, pathologists, and other healthcare professionals by offering up-to-date insights into the clinical aspects of biological medications and their biosimilars. Contributions from global experts ensure readers gain the latest advancements and practical guidance on integrating these therapies into clinical practice and research.

  • Cadmium Contamination in Soils and Plants

    Mechanisms and Mitigation
    • 1st Edition
    • Fang-Jie Zhao + 2 more
    • English
    Cadmium Contamination in Soils and Plants presents a rigorous, up-to-date account of how this toxic metal enters agricultural landscapes, persists in soils, interacts with living systems, and ultimately affects food safety and human health. The volume synthesizes cutting-edge findings on the processes that drive Cd movement from soil to crops and clarifies the biological pathways by which plants and microorganisms respond. It translates scientific insight into practical solutions for safer agricultural production systems, drawing on recent advances in measurement, modeling, and remediation.This book is intended for researchers, graduate students, and professionals across environmental science, agronomy, and public health who need an authoritative, research-grounded reference to inform decisions in cultivation-related settings.

  • Nanoengineered Therapeutics for Lung Cancer

    Advanced Drug Delivery Strategies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanoengineered Therapeutics for Lung Cancer: Advanced Drug Delivery Strategies explores contemporary methods for diagnosing and treating lung cancer using cutting-edge nanotechnology. The book provides a foundational understanding of lung cancer biology, detailing innovative nanodrug delivery strategies and their practical applications in treatment. The content is strategically structured, covering the design, synthesis, and application of nanodrug delivery systems. Chapters delve into specific technologies such as gold nanoparticles, exosome-mediated therapies, and siRNA-based gene silencing. The book also addresses challenges like drug resistance and toxicity, offering insights into future research directions and advancements in the field. This book benefits graduate students, researchers, and healthcare professionals by seamlessly integrating theoretical concepts with practical applications. It serves as an essential educational resource, equipping readers with the knowledge and skills needed to tackle complex challenges in lung cancer treatment using nanomedicine. This comprehensive guide ensures that readers stay at the forefront of the rapidly evolving landscape of cancer therapeutics.

  • Native and Modified Starches for Food Applications

    • 1st Edition
    • Pothiyappan Karthik + 2 more
    • English
    Native and Modified Starches for Food Applications, a volume in the Applications of Starches in Food and Packaging series, provides an in-depth exploration of the diverse types and sources of starches, their functional properties, and their applications in various culinary contexts. Chapters cover the gelatinization process, texture modification, and sustainable utilization of starches in addition to exploring future directions in starch research and applications. As the food industry continues to seek natural, functional ingredients, this resource meets the demand for a comprehensive and up-to-date exploration of the use of starches in food applications.Users will find this to be a great resource for facilitating informed decision-making in recipe development, processing techniques, and the creation of innovative, sustainable, and gluten-free food products.

  • Laser Polarization and Autofluorescence Imaging for Biomedical and Clinical Applications

    • 1st Edition
    • Alexander Ushenko
    • English
    Laser Polarization and Autofluorescence Imaging for Biomedical and Clinical Applications addresses the cutting-edge research area of laser and autofluorescence polarimetric visualization combined with sophisticated multi-algorithm digital analysis. The book’s content spans ten detailed sections, covering fundamental theories of Mueller-matrix polarimetry, azimuth-invariant mapping methods, advanced Fourier and wavelet transformations, singular analysis, laser-induced autofluorescence polarimetry, and biomedical system architectures. It culminates with clinical application examples demonstrating early diagnostics of malignancies, type 2 diabetes, albuminuria, cholelithiasis, septic conditions, and forensic determinations such as cause and time of death.This reference offers significant benefits to researchers, biomedical engineers, and medical data analysts by delivering a pioneering synthesis of the latest theoretical concepts and multifunctional digital imaging methods. It equips the audience with objective, highly sensitive digital markers essential for accurate, rapid preclinical diagnostics, thereby advancing precision medicine and evidence-based clinical practice in biomedical optics.

  • Bio-Click Chemistry

    Expanding Horizons Beyond the Click
    • 1st Edition
    • Flavia Zacconi + 2 more
    • English
    Bio-Click Chemistry: Expanding Horizons Beyond the Click delves into the dynamic intersection of biocatalysis and click chemistry, providing a comprehensive exploration of these rapidly evolving fields. This book offers in-depth insights into both historical perspectives and the latest advancements, ensuring readers gain a thorough understanding of fundamental principles, practical applications, and future directions. Readers will discover the versatile applications of biocatalysis and click chemistry in pharmaceuticals, biotechnology, biology, biomedicine, nanomedicine, and materials science, equipping researchers, educators, and industry professionals with the tools and techniques needed to foster innovation and real-world impact. Furthermore, the book investigates the emerging trends, challenges, and opportunities in biocatalysis and click chemistry, empowering readers to stay ahead of the curve and drive transformative developments in chemical synthesis and enzymatic engineering. This indispensable guide is designed for researchers, educators, and industry professionals dedicated to advancing their work and exploring new frontiers in chemical synthesis and biocatalytic processes.

  • Diagnostic Reasoning

    Laboratory-Based Case Studies in Clinical Chemistry
    • 1st Edition
    • Ibrahim A. Hashim
    • English
    Training in clinical chemistry is acquired via different avenues that include didactic lectures on pathophysiology of disease, methodologies and practical aspects of testing, and through attendance of operations meetings, sign-out sessions, seminars and tutorials. There is little instruction on how to apply the vast amount of knowledge gained in the process to practice. In other branches of medicine, cases are regularly presented with clinical information and therapeutic interventions which form the basis of training. Diagnostic Reasoning: Laboratory-Based Case Studies in Clinical Chemistry fills this gap for clinical chemistry. The concise and practical approach of the book, including real-life scenarios, is an excellent resource for pathology trainees, clinical laboratory science students, clinical chemistry fellows, clinical laboratory professionals, and clinicians. These cases help professionals remain competent in the field and be successful in their board exams. The cases are stated as they present, often with no or few clinical details accompanying the sample request with only barcoded samples arriving into the laboratory. In a busy laboratory, thousands of these cases are received daily and it is impossible to review the clinical information associated with the specimens.

  • Advanced MR Techniques for Neurodegenerative Diseases

    • 1st Edition
    • Volume 13
    • Kannie Wy Chan + 3 more
    • English
    Advanced MR Techniques for Neurodegenerative Diseases covers state of the art developments in physiologic, metabolic, functional, and microstructural MRI of the brain. It provides an overview of these approaches and includes dynamic contrast enhanced (DCE) MRI, dynamic susceptibility contrast (DSC) MRI, arterial spin labeling (ASL), chemical exchange saturation transfer (CEST) MRI, magnetic resonance spectroscopy (MRS), resting state functional MRI (rsfMRI), microscopic diffusion imaging, and quantitative susceptibility mapping (QSM). Chapters then follow that present the application of these methods to Alzheimer’s Disease and vascular dementia, small vessel disease, Parkinson’s Disease, Lewy body dementia, Huntington’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis.Advanced MR Techniques for Neurodegenerative Diseases is a comprehensive resource on the latest advanced MR techniques and their application to neurodegenerative diseases, suitable for MR engineers and physicists as well as clinicians and neuroscientists who use MR techniques for diagnosis and research.

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