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Books in Life sciences

  • Ingredient X

    The Production of Effective Drugs
    • 1st Edition
    • Louis C. Schroeter
    • English
    Ingredient X: The Production of Effective Drugs deals with various aspects of pharmaceutical research and development, with emphasis on the importance of formulation ingredients on drug effectiveness and the role of the pharmaceutical development scientist in designing dosage forms for modern drugs. More than 50 illustrations are used to explain experiments and ""tools of the trade"". This book is comprised of four chapters and opens with an overview of research and development in the pharmaceutical industry, paying particular attention to the kind of work done by scientists according to the degree or level of training. The additives or so-called ""inert"" ingredients used in drug formulation are also considered. The next chapter explains how adding just the right amount of some ""inert"" ingredient—a factor X—can enhance the acceptability of a product to the user. The importance of maintaining drug potency in a dosage form, mainly through refrigeration or storage in cool places, is then discussed. The final chapter looks at the factors to consider to achieve the best possible drug formulation and most effective dosage form, including the safety factor. The need to establish correlations between laboratory quality tests and product performance during the development phase is highlighted. This monograph will be a useful resource for pharmacologists and pharmaceutical development scientists.
  • Providing Pharmacological Access to the Brain

    Alternate Approaches
    • 1st Edition
    • Volume 21
    • Thomas R. Flanagan + 1 more
    • English
    This volume focuses on contemporary approaches for delivering experimental and therapeutic agents into the brain. The contributions provide methodological details that are typically not available in the literature. Subtleties and shortcuts critical to each procedure are included to facilitate their use by both the experienced researcher and novice.
  • Human Ecology in the Tropics

    Symposia of The Society for The Study of Human Biology
    • 1st Edition
    • J. P. Garlick + 1 more
    • English
    Symposia of the Society for the Study of Human Biology, Volume 9: Human Ecology in the Tropics covers papers related to the impact of human on the natural ecosystems in tropical countries. The volume presents papers about the operation of typical plant-soil systems in relation to human activity in West Africa; the interrelationships of habitat, economy, and society among three Guiana people; tropical health; and the use and production of tropical food potentials. The book also describes papers about the ecology of African schistosomiasis, as well as the interaction between the trypanosome-tsetse-w... fauna ecosystem and the surrounding human communities of southern Busoga in Uganda. The volume concludes by discussing the development of young children in a West African village. Ecologists and biologists will find the book invaluable.
  • Trends in Receptor Research

    Proceedings of the 8th Camerino-Noordwijkerhout Symposium, Camerino, Italy, 8-12 September 1991
    • 1st Edition
    • Volume 18
    • P. Angeli
    • English
    The 8th Camerino-Noordwijker... Symposium has continued along its traditional path of interdisciplinary cooperation. Chemists, biochemists, pharmacologists, biophysicists and physiologists are all involved in the task of improving our knowledge of the mechanisms of drug-receptor interaction and of the heterogeneous nature of biological molecules. In this volume, leading researchers have contributed state of the art information on receptor chemistry. Newest developments are covered with particular reference to receptors of the nervous system; SAR studies; receptor isolation; receptor cloning; receptor topography; biomedical consequences of occupancy; receptor regulation and receptor theory. This will be of great interest to pharmacologists, biochemists and medicinal chemists, as well as a valuable source of reference for medical students and postgraduate students in related fields.
  • India and the Far East

    A Geography of Disease and Sanitation
    • 3rd Edition
    • James Stevens Simmons + 2 more
    • English
    Global Epidemiology: A Geography of Disease and Sanitation, Volume I presents a survey of the medical, health, and sanitary conditions of various geographic areas of the world. The book brings together certain data, based on surveys made for the Medical Department of the United States Army. This volume includes medical information about India, the Far East, and the Pacific area. The text aims to provide vital information to meet the problems of international health and the spread of disease. The monograph will be of use to epidemiologists, health workers, physicians, and public health experts.
  • Plate Tectonics & Crustal Evolution

    • 2nd Edition
    • Kent C. Condie
    • English
    Plate Tectonics & Crustal Evolution, Second Edition covers the role of plate tectonics in the geologic past in light of existing geologic evidence, and examples of plate reconstructions. The book discusses the important physical and chemical properties of the crust and upper mantle in terms of models for crustal origin and evolution. The text also describes sea-floor spreading; magma associations; plate tectonics and continental drift. The phanerozoic orogenic systems and the precambrian crustal development are also tackled. The book will be invaluable to students in the earth sciences and to various specialists in the geological sciences.
  • Advances in Drug Research

    • 1st Edition
    • Volume 18
    • Bernard Testa
    • English
    Each volume in this distinguished series presents authoritative reviews, both generally, on topics of broad interest in drug research, and specifically, on novel and established therapeutic classes. Acknowledged experts contribute in areas such as drug design, clinical and molecular pharmacology, drug metabolism, and mechanisms of action. Reviewers have consistently praised Advances in Drug Research for its comprehensive and lucid summaries of up-to-date knowledge.
  • Neurobiology of Cytokines, Part B

    • 1st Edition
    • Volume 17
    • P. Michael Conn + 1 more
    • English
    Recent data suggest a critical role for cytokines in the regulation of brain and endocrine function under normal physiological conditions. The aim of this volume and its companion Volume 16 is to provide an overview of the effects of cytokines in the brain and in the endocrine system.
  • Genetic Interactions Among Microorganisms in the Natural Environment

    • 1st Edition
    • E.M.H. Wellington + 1 more
    • English
    This book gives an overview of gene transfer and stability in those aquatic and terrestrial environments where bacteria and fungi can survive and interact genetically. It examines the role played by sex between microbes in the evolution of populations and their survival. Special emphasis is placed on methodology, including the analysis by novel techniques of genetic material extracted directly from soils, rivers and lakes. The natural spread of antibiotic resistance and the safe use of genetically manipulated microbes are matters of considerable scientific, medical and public concern upon which the investigations presented here have direct bearing. This unique collection will be of value to specialist researchers in applied microbiology, ecology and biotechnology as well as biomedical scientists interested in the environmental risks of genetic engineering.
  • Animal Biotechnology

    Comprehensive Biotechnology, First Supplement
    • 1st Edition
    • L.A. Babiuk + 2 more
    • English
    The advent of biotechnology has the potential to develop a variety of novel or better quality products for the treatment of a large number of diseases in livestock. In addition, as we understand more about the reproductive physiology of animals, the potential exists to dramatically increase the productivity of animals through better therapeutics and diagnostics for the control of many infectious diseases. Productivity can also be increased through animal breeding strategies including gene transfer, micromanipulation of embryos and gamete sex selection. As well as being a valuable reference to current knowledge in these areas, this first supplement to Comprehensive Biotechnology also looks at societal concerns over the use of antibiotics and chemical residues in meat and milk products, which are forcing biotechnologists to investigate more natural means of controlling infection by stimulating the animal's own immune system to combat infection. The identification of a variety of cytokines which are involved in regulating immune responses provides opportunities to use the animal's natural defence mechanisms to combat many infections or increase the animal's resistance to such infections. These approaches should provide tools for eventual elimination of specific diseases from counties, regions or whole continents.