Skip to main content
View Cart

Books in Life sciences

  • Brain Imaging

    An Introduction
    • 1st Edition
    • October 22, 2013
    • John R. Bradshaw
    • English
    Brain Imaging: An Introduction presents diverse manifestations of brain disease as shown by neuroradiology. It discusses the full potential of new diagnostic techniques. It addresses the technique most appropriate for a given injury. Some of the topics covered in the book are the plain skull radiographs; plain-film tomography; radionucleic brain scanning; cerebral angiography; pituitary and parasellar lesions; sensory disorders; malignant glioma; the posterior fossa and cranial nerves; dementia and psychotic states; imaging tecniques in brain diagnosis; and metastatic disease. The definition of craniotomy is covered. The hyperostosis of sphenoid wing is discussed. The text describes the skull fracture, intracranial air, and leptomeningeal cyst. A study of the cerebral ultrasound and cerebral angiography are presented. A chapter is devoted to the angiographic pathology and computerized axial tomography. Another section focuses on the use of magnetic resonance imaging. The book can provide useful information to radiologists, doctors, physical therapists, students, and researchers.

  • Symposium on Clinical Pharmacology

    Biochemical Pharmacology
    • 1st Edition
    • October 22, 2013
    • William A. Creasey + 2 more
    • English
    Symposium on Clinical Pharmacology reviews advances in clinical pharmacology, with emphasis on how to materially improve the efficacy of cancer chemotherapy. Topics range from absorption, protein binding, distribution, and excretion of antineoplastic drugs to factors affecting the biotransformation and activity of antitumor drugs. The transport of tumor-inhibitory agents across cell membranes is also examined, together with factors influencing drug selectivity and the mechanisms of clinical drug resistance. This volume is comprised of 23 chapters and begins with a brief summary of the different kinds of pharmacokinetic models and how detailed kinetic investigations of a drug in animals may provide further insight into modes of its clinical use. The next chapter considers the chief factors in determining the effective concentration of a drug at a receptor site as well as the duration and intensity of drug effect, citing antineoplastic agents as examples. The role of enzymatic activation and inactivation in drug selectivity is also discussed, along with the general mechanisms of clinical resistance to cancer chemotherapy; biochemical and pharmacological principles of combination chemotherapy; and the reaction and effects of nitrosoureas. This book will be of interest to clinicians, pharmacologists, and biochemists.

  • Pigment Cell Growth

    Proceedings of the Third Conference on the Biology of Normal and Atypical Pigment Cell Growth
    • 1st Edition
    • October 22, 2013
    • Myron Gordon
    • English
    Pigment Cell Growth covers the proceedings of the Third Conference on the Biology of Normal and Atypical Pigment Cell Growth. The book focuses on the nature of the pigment cell and its contained melanin. The selection first offers information on the origin of the mammalian pigment cell and its role in the pigmentation of hair and relations between developing melanophores and embryonic tissues in the Mexican axolotl. The book also examines the genetic control of pigmentation in the fowl; relationship of atypical pigment cell growth to gonadal development in hybrid fishes; and estrogen, thyroid hormone, and the differentiation of pigment cells in the brown leghorn. The publication takes a look at dendritic melanoblasts in metastatic squamous cell carcinoma; microscopic analysis of normal melanoblasts, nevus cells, and melanoma cells; and analysis of skin color in living human subjects by spectrophotometric means. The selection is a dependable source of data for readers interested in pigment cell growth.

  • Steroid Hormone Regulation of the Brain

    Proceedings of an International Symposium Held at the Wenner-Gren Center, Stockholm, 27-28 October 1980
    • 1st Edition
    • October 22, 2013
    • Kjell Fuxe + 2 more
    • English
    Steroid Hormone Regulation of the Brain focuses on the advancement of knowledge of the properties of brain steroid receptors and steroid target nerve cells, including the actions of gonadal steroids, adrenocortical steroids, and androgenic steroids on the brain. The selection features the work of authors who have inspiringly conducted extensive studies on the action of steroid hormones. The book starts with discussions that point out that steroid hormones not only function through intracellular steroid receptors, but possibly through steroid membrane actions as well. Studies to support this claim are presented. As to the action of steroid hormones on presynaptic transmitter mechanisms, the book suggests that adrenocortical and gonadal steroids can create alterations in noradrenaline, adrenaline, and dopamine levels and turnover within the hypothalamus and preoptic area. The effects of catecholestrogens on the brain are also elaborated. A contribution to this paper stresses that estrogens have antidopaminergic action in the extrapyramidal system. This idea is identified through a series of behavioral experiments and measurements of the levels of striatal acetylcholine. This selection is recommended to scientists interested in studying the effect of hormones on the brain.

  • Steroidal Activity in Experimental Animals and Man

    • 1st Edition
    • October 22, 2013
    • Ralph I. Dorfman
    • English
    Methods in Hormone Research, Volume IV: Steroidal Activity in Experimental Animals and Man, Part B focuses on protection against irradiation damage, anti-mammary tumor activity, anti-androgens, steroids, and anti-progestational compounds. The selection first offers information on the thermogenic properties of steroids and anabolic steroids, as well as characteristics of steroid pyrogen action in man; species specificity of steroid pyrogen action; clinical significance of thermogenic steroids; and relative activity of anabolic steroids in animals and man. The book also ponders on anti-androgens and anti-progestational compounds. The manuscript examines steroids in reactivated prostatic cancer and tumorigenesis in experimental animals. Discussions focus on treatment and nature of relapse, cooperative study program, mammary and pituitary tumors, testicular interstitial cell tumors, and neoplasms of the female genital tract. The text then elaborates on inhibition of tumor growth by steroids and the effect of corticoids and ACTH on the induction of gastric ulcers in laboratory animals. The selection is a dependable reference for readers interested in steroidal activity in man and animals.

  • Diagnostic Reference Index of Clinical Neurology

    • 2nd Edition
    • October 22, 2013
    • Pasquale F. Finelli
    • English
    Diagnostic Reference Index of Clinical Neurology aims to give the busy clinician a fast, easy-to-use guide to the core neurological literature published from 1980 to 1986. This book is divided into two sections, key words and references. The keywords section consists of neuroscience terms and each main entry is followed by reference citation numbers and corresponding references. This index, unlike the usual computerized systems for literature retrieval, is structured around clinical problems and uses the approach and terminology of a practicing neurologist. The contents were sources from the full text of articles that were published in critical core of fourteen major international English-language journals in medicine and neurology. This book will be of interest to neurology students and to practicing clinical neurologists.

  • Methods in Polyphenol Chemistry

    Proceedings of the Plant Phenolics Group Symposium, Oxford, April 1963
    • 1st Edition
    • October 22, 2013
    • J. B. Pridham
    • English
    Methods in Polyphenol Chemistry documents the proceedings of the Plant Phenolics Group Symposium held at the University of Oxford, on 2-4 April 1963. The symposium focused on the methods and techniques which made advances in the chemistry and biochemistry of phenolic compounds possible. The development of paper chromatographic and ultraviolet spectroscopic techniques was particularly important and largely responsible for the rapid growth in knowledge of polyphenols which has occurred during the last 10-15 years. In addition to these two methods other spectroscopic techniques were dealt with at the symposium. Particular mention should perhaps be made of nuclear magnetic resonance spectroscopy which is becoming increasingly important in polyphenol chemistry. Modern chromatographic methods such as thin layer and gas-liquid techniques will probably be used extensively in the future. These will enable the analyses of polyphenol mixtures to be carried out more rapidly and with greater resolution. Polyamide chromatography also has high powers of resolution, although this technique has not been widely used owing to difficulties in obtaining supplies of polyamide powder. This situation has now improved, however.

  • The Clinical Aspects of Some Diseases of Cats

    • 1st Edition
    • October 22, 2013
    • Joan O. Joshua
    • English
    The Clinical Aspects of Some Diseases of Cats describes certain cat diseases as it occurs in the British Isles. This book is composed of 23 chapters that specifically examine conditions which occur, their relative frequency, detail symptomatology, and methods of diagnosis and treatment available in the average practice. The first chapters deal with the relationship of cat with man, its restraint, sedation, anesthesia, health, and clinical examination. Considerable chapters are devoted to numerous diseases in cat's head, eye, mouth, ear, alimentary tract, internal organs, peritoneal cavity, reproductive, nervous, and skeletal system, and skin. The remaining chapters describe diseases due to infective agents and sepsis. These chapters also discuss issues on quarantine, veterinary cat examinations, and cat shows. This book will prove useful to veterinarians, clinicians, and cat handlers and owners.

  • Pharmaceutical and Biomedical Applications of Liquid Chromatography

    • 1st Edition
    • Volume 1
    • October 22, 2013
    • W.J. Lough + 2 more
    • English
    This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures.The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored.Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media.The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

  • Food Legislative System of the UK

    • 1st Edition
    • October 22, 2013
    • Stephen J. Fallows
    • English
    Food Legislative System of the UK discusses the principles underlying the country's food laws, the historical context of today's food legislation, and the process for amendments in legislation. The book also reviews the influences on the system such as those arising from interest groups, the changing diet, and health environment. In addressing the Food Legislative System of the United Kingdom, the book tackles various examples of food legislation and numerous food- related advisory bodies. Industry, consumer, or enforcement pressures can initiate changes and modifications of laws. Once ministers are convinced that a prima-facie case exists for amending food legislation, they will seek advice from various authorities; make a draft, and present it for full parliamentary procedure. For example, the "Food and Environment Bill" has passed through Parliament by ministers representing the Ministry of Agriculture, Fisheries and Food, while the "Food Bill" has gone through another route with the chief legal officers and company. The book emphasizes the mechanisms through which change is achieved, as well as the points when opportunities exist for interest groups to make their views known to the decision makers. The book can be helpful for food lobbyists, consumer food groups, nutritionists, political scientists, and heads of food and welfare organizations.

Related subjects