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    • Development of Anti-Asthma Drugs

      • 1st Edition
      • October 22, 2013
      • Derek R. Buckle + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 6 6 6 6
      • eBook
        9 7 8 1 4 8 3 1 9 2 4 7 5
      Development of Anti-Asthma Drugs reviews existing asthma treatments and novel approaches currently under investigation, in the context of their mode of action and clinical effectiveness, in the hope that this might lead to a greater understanding of the factors involved in the expression of the disease and, therefore, in the design of better drugs. It is planned based on the concept of the causes and treatment of asthma, This book is organized in three main parts. Part I deals with the nature of asthma, its pathological mechanisms, natural history and epidemiology. Part II discusses mediators associated with asthma including platelet-activating factor, leukotrienes and histamine. Part II covers pharmaceutical approaches in the development of anti-asthma drugs and includes sections on inhibitors of mediator release and competitive and functional antagonists. This book will be of interest to persons dealing with studies on anti-asthma drugs and those interested in pharmacological development.

    • Recent Progress in Hormone Research - Volume 49

      • 1st Edition
      • October 22, 2013
      • C. Wayne Bardin
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 9 0 2 1
      Among the topics covered in Volume 49 are neurotransmitter transporters circadian rhythms, transgenic model for studying isles development, protein phosphateses, the androgen receptor, molecular genetics of steroid 5oz-reductases and benign and malignant prostatic neoplasms.

    • Biological Functions of Microtubules and Related Structures

      • 1st Edition
      • October 22, 2013
      • Hikoichi Sakai + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 6 1 5 0 8 0 3
      • Paperback
        9 7 8 1 4 8 3 2 4 6 0 7 9
      • eBook
        9 7 8 1 4 8 3 2 7 2 2 0 7
      Biological Functions of Microtubules and Related Structures is a compendium of papers presented at the 13th Oji International Seminar on The Biological Functions of Microtubules and Related Structures, held at Komaba Eminence in Tokyo in November, 1981. The papers discuss the molecular function of tubulin in various biological processes or events. The book is divided into six sections focusing on the various aspects of the functions and structures of microtubules -- the biochemistry and molecular biology of tubulin, including regulation of microtubule assembly; microtubule-dynein systems and other proteins in cell motility; microtubules and related proteins in mitosis; the interactions of cytoskeletal components; the cytoskeleton; and microtubules in membrane functions and transport. Biochemists, biologists, and molecular biologists will find the book interesting.

    • Endocrinology 1971

      • 1st Edition
      • October 22, 2013
      • Selwyn Taylor
      • English
      • Hardback
        9 7 8 0 4 3 3 3 2 2 0 2 3
      • Paperback
        9 7 8 1 4 8 3 1 2 9 7 3 0
      • eBook
        9 7 8 1 4 8 3 1 6 2 1 5 7
      Endocrinology 1971 is a collection of papers that discusses the endocrine polypeptides and their secreting cells. The book presents a total of 56 materials that are organized into 10 parts. The text first covers the chemical aspects of endocrinology, and then proceeds to discussing much more specialized areas. The coverage of the book includes embryological origin of endocrine cells; gastrointestinal hormones; and parathyroid hormone and calcitonin. The book will be of great use to researchers in the field of biology and medicine, particularly those who specialize in the endocrine system.

    • Biospeleology

      • 1st Edition
      • September 11, 2013
      • A. Vandel
      • G. A. Kerkut
      • English
      • Paperback
        9 7 8 1 4 8 3 1 6 9 3 2 3
      • eBook
        9 7 8 1 4 8 3 1 8 5 1 3 2
      Biospeleology: The Biology of Cavernicolous Animals discusses the fundamental concepts in understanding the biological make up of cave-dwelling animals. The title aims to relate the subterranean world as a habitat for organisms. The first part of the text tackles basic concerns, such as the concept of the subterranean world and cavernicoles, along with the history and research concerns in biospeleology. Next, the selection enumerates the subterranean flora and fauna, along with the geographical distribution and ecology of cavernicoles. The next two parts detail the physiology and behavior of cavernicoles, while the last part tackles the evolution of cavarnicoles. The book will be of great interest to zoologists, biologists, and ecologists who wish to gain a better understanding of the biological properties of subterranean organisms.

    • Drug Design

      • 1st Edition
      • October 22, 2013
      • E. J. Ariëns
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 6 1 7
      • eBook
        9 7 8 1 4 8 3 2 1 6 0 4 1
      Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase... drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes and their synthesis as a target for antibiotic action. The rational design of antiviral agents; the design of penicillin; the design of peptide hormone analogs; as well as the advances in the design of diuretics are also considered. The book further tackles the design of biologically active steroids; the rational elements in the development of superior neuromuscular blocking agents; and the design of tumor-inhibitory alkylating drugs. Pharmacologists, chemists, and people involved in drug design will find the book invaluable.

    • Utilization of Nutrients During Postnatal Development

      • 1st Edition
      • October 22, 2013
      • P. Hahn + 1 more
      • G. A. Kerkut
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 0 1 2 1
      • eBook
        9 7 8 1 4 8 3 1 8 5 9 3 4
      Utilization of Nutrients during Postnatal Development investigates the nutritional aspects of postnatal development, with emphasis on functions that in some way are closely connected to food, including food intake, digestion, transport, and metabolism. Topics covered range from energy sources and energy balance in starvation to the quantitative and qualitative aspects of food intake. The fate of carbohydrates in infant animals is also discussed, along with the metabolism of lipids during postnatal development. Comprised of eight chapters, this volume begins with an analysis of the most important differences between adult and suckling rats, paying particular attention to thermoregulation and the action of hormones in the early postnatal period. Subsequent chapters deal with the effect of starvation at two environmental temperatures on losses in body weight; protein as an energy source; the absorption of glucose from the gastrointestinal tract; and energy metabolism in the human fetus and newborn. The final chapter is devoted to the late effects of changes in diet composition during the weaning period. This book will be useful for students, practitioners, and researchers in physiology, biology, and developmental nutrition.

    • Symbiosis

      • 1st Edition
      • September 17, 2013
      • S. Mark Henry
      • English
      • Hardback
        9 7 8 1 4 8 3 2 2 7 5 8 0
      • Paperback
        9 7 8 1 4 8 3 2 5 0 8 3 0
      • eBook
        9 7 8 1 4 8 3 2 7 5 9 2 5
      Symbiosis, Volume II: Associations of Invertebrates, Birds, Ruminants, and Other Biota focuses on associations involving insects, birds, and terrestrial vertebrates, as well as ectosymbiosis and endosymbiosis. The selection first offers information on insects and their endosymbionts and insect ectosymbiosis. Discussions focus on distribution of endosymbioses in insects; behavior of symbionts during embryogeny; physiological problems of insect symbioses; and miscellaneous insect symbioses. The manuscript also elaborates on ectosymbiosis in wood-inhabiting insects and aquatic insects. The book takes a look at avian symbiosis and intestinal microorganisms of ruminants and other vertebrates, as well as areas in which symbiosis affects birds and biochemical processes in the lower part of the alimentary tract of ruminants and in nonruminants. The selection is a dependable reference for readers interested in the relationships of insects, birds, and terrestrial vertebrates.

    • Symposium on Clinical Pharmacology

      • 1st Edition
      • October 22, 2013
      • William A. Creasey + 2 more
      • English
      • Paperback
        9 7 8 0 0 8 0 1 8 9 4 9 9
      • eBook
        9 7 8 1 4 8 3 1 3 9 4 0 1
      Symposium on Clinical Pharmacology reviews advances in clinical pharmacology, with emphasis on how to materially improve the efficacy of cancer chemotherapy. Topics range from absorption, protein binding, distribution, and excretion of antineoplastic drugs to factors affecting the biotransformation and activity of antitumor drugs. The transport of tumor-inhibitory agents across cell membranes is also examined, together with factors influencing drug selectivity and the mechanisms of clinical drug resistance. This volume is comprised of 23 chapters and begins with a brief summary of the different kinds of pharmacokinetic models and how detailed kinetic investigations of a drug in animals may provide further insight into modes of its clinical use. The next chapter considers the chief factors in determining the effective concentration of a drug at a receptor site as well as the duration and intensity of drug effect, citing antineoplastic agents as examples. The role of enzymatic activation and inactivation in drug selectivity is also discussed, along with the general mechanisms of clinical resistance to cancer chemotherapy; biochemical and pharmacological principles of combination chemotherapy; and the reaction and effects of nitrosoureas. This book will be of interest to clinicians, pharmacologists, and biochemists.

    • Food Industry Wastes

      • 1st Edition
      • January 31, 2013
      • Maria R. Kosseva + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 1 9 2 1 2
      • Paperback
        9 7 8 0 1 2 8 1 0 2 5 4 1
      • eBook
        9 7 8 0 1 2 3 9 1 9 2 8 1
      Food Industry Wastes: Assessment and Recuperation of Commodities presents emerging techniques and opportunities for the treatment of food wastes, the reduction of water footprint, and creating sustainable food systems. Written by a team of experts from around the world, this book provides a guide for implementing bioprocessing techniques. It also helps researchers develop new options for the recuperation of these wastes for community benefit. More than 34 million tons of food waste was generated in the United States in 2009, at a cost of approximately $43 billion. And while less than three percent of that waste was recovered and recycled, there is growing interest and development in recovering and recycling food waste. These processes have the potential not only to reduce greenhouse gases, but to provide energy and resources for other purposes. This book examines these topics in detail, starting with sources, characterization and composition of food wastes, and development of green production strategies. The book then turns to treatment techniques such as solid-state fermentation and anaerobic digestion of solid food waste for biogas and fertilizer. A deep section on innovative biocatalysts and bioreactors follows, encompassing hydrogen generation and thermophilic aerobic bioprocessing technologies. Rounding out the volume are extensive sections on water footprints, including electricity generation from microbial fuel cells (MFCs), and life cycle assessments.

Related subjects

Agricultural and biological sciences

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