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Books in Life sciences

  • The Squirrel Monkey

    • 1st Edition
    • November 6, 2013
    • Leonard A. Rosenblum + 1 more
    • English
    The Squirrel Monkey is devoted to the common South American squirrel monkey, Saimiri sciureus. In light of the growing number of squirrel monkeys being established each year in many laboratories, there appeared the need to pool existing knowledge in concise form. The present volume, the first of its kind on any single primate, attempts to meet this need. The topics that have been selected cover thoroughly areas of research in which Saimiri has been utilized. This material ranges widely from taxonomy and behavioral studies through husbandry and clinical management of the species, to investigations in aerospace medicine and in a number of basic biological sciences. Since the problems encountered in the squirrel monkey, though sometimes taking a particular form, are not unique in principle, the authors have attempted to provide an appropriate phylogenetic context for their material. It is hoped as a result that this compendium may serve as a valuable source of information during various phases of work on other subjects of primatological and comparative biological investigation as well.

  • Circadian Rhythms and the Human

    • 1st Edition
    • November 6, 2013
    • D. S. Minors + 1 more
    • English
    Circadian Rhythms and the Human covers the basic principles behind the human circadian rhythms. This book is composed of 12 chapters that discuss the detection, analysis, and definition of rhythms, specifically exogenous and endogenous rhythms. This book also demonstrates the mechanism of metabolic and gastrointestinal rhythms. The opening chapters deal with the rhythms in living organism; establishing the endogeneity of rhythms; definition of nychthemeral rhythm; methods of measuring the frequency of rhythms; exogenous effects upon the temperature rhythm; interaction between exogenous and endogenous influences; and possible origins of renal rhythmicity. The succeeding chapters consider the effect of exercise at different times of day and the concept of sleep-wakefulness rhythm. The discussion then shifts to the effects of repeated time-zone transitions and the effects of time on drug administration. The closing chapters are devoted to the assessment of work performance during shift work. The book can provide useful information to doctors, students, researchers, and the general reader.

  • Aspects of Cell Regulation

    • 1st Edition
    • November 6, 2013
    • G. H. Bourne + 1 more
    • English
    Aspects of Cell Regulation deals with the various aspects of cellular control mechanisms. The book begins with a discussion of the role of hormones in the control of cell differentiation and biochemical control over the life of an organism. This is followed by separate chapters on an intracellular control problem, namely, the proper reproduction of cellular organelles and their apportionment between daughter cells at cell mitosis; cell mutants with different temporal order for macromolecular synthesis; and the control of a plant enzyme that converts triglycerides into carbohydrate during the early stages of postgerminative growth within seed cotyledon. Subsequent chapters deal with the possible role of mitochondria in changing the control mechanism of cells to that associated with carcinogenesis; the possibility of transforming genes being detectable in the genome after the transformation to neoplastic cell; the correlation between viruses and tumor cells; and whether viruses can originate from cells rather than coming before cells.

  • The Beginnings of Electron Microscopy

    • 1st Edition
    • November 6, 2013
    • Peter W. Hawkes
    • English
    The Beginnings of Electron Microscopy presents the technical development of electron microscope. This book examines the mechanical as well as the technical problems arising from the physical properties of the electron. Organized into 19 chapters, this book begins with an overview of the history of scanning electron microscopy and electron beam microanalysis. This text then explains the applications and capabilities of electron microscopes during the war. Other chapters consider the classical techniques of light microscopy. This book presents as well the schematic outline of the preparation techniques for investigation of nerve cells by electron microscopy. The final chapter deals with the historical account of the beginnings of electron microscopy in Russia. This book is a valuable resource for scientists, technologists, physicists, electrical engineers, designers, and technicians. Graduate students as well as researcher workers who are interested in the history of electron microscopy will also find this book extremely useful.

  • Functional Organization of Vertebrate Plasma Membrane

    • 1st Edition
    • Volume 72
    • November 5, 2013
    • English
    Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume covers recent breakthroughs in understanding the molecular and cellular basis for patterning vertebrate plasma membranes. A special emphasis is placed on physiological function with chapters covering signaling in the nervous system and heart, vision, and the immune system.

  • Bio-nanoimaging

    Protein Misfolding and Aggregation
    • 1st Edition
    • November 5, 2013
    • Vladimir N Uversky + 1 more
    • English
    Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering:- Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobuli... studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers- Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties.

  • Diffusion MRI

    From Quantitative Measurement to In vivo Neuroanatomy
    • 2nd Edition
    • November 4, 2013
    • Heidi Johansen-Berg + 1 more
    • English
    Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.

  • Animal Biotechnology

    Models in Discovery and Translation
    • 1st Edition
    • November 4, 2013
    • Ashish S. Verma + 1 more
    • English
    Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences.

  • Endovascular Management of Neurovascular Pathology in Adults and Children, An Issue of Neuroimaging Clinics

    • 1st Edition
    • Volume 23-4
    • November 1, 2013
    • Neeraj Chaudhary + 1 more
    • English
    This issue of Neuroimaging Clinics focuses on the endovascular treatment of pathology in adults and children. Topics include cerebral aneurysms, cerebral vasospasms, dural fistulas, carotid stenosis, acute ischemic stroke, vascular malformations, and more.

  • Food Safety Management

    A Practical Guide for the Food Industry
    • 1st Edition
    • November 1, 2013
    • Huub Lelieveld + 1 more
    • English
    Food Safety Management: A Practical Guide for the Food Industry with an Honorable Mention for Single Volume Reference/Science in the 2015 PROSE Awards from the Association of American Publishers is the first book to present an integrated, practical approach to the management of food safety throughout the production chain. While many books address specific aspects of food safety, no other book guides you through the various risks associated with each sector of the production process or alerts you to the measures needed to mitigate those risks. Using practical examples of incidents and their root causes, this book highlights pitfalls in food safety management and provides key insight into the means of avoiding them. Each section addresses its subject in terms of relevance and application to food safety and, where applicable, spoilage. It covers all types of risks (e.g., microbial, chemical, physical) associated with each step of the food chain. The book is a reference for food safety managers in different sectors, from primary producers to processing, transport, retail and distribution, as well as the food services sector.

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