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Elsevier

Books in Life sciences

  • The Antigens

    Volume II
    • 1st Edition
    • Michael Sela
    • English
    The Antigens, Volume II is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from protein antigens and blood group antigens to low molecular weight antigens and immunoglobulin A. The idiotypy of antibodies is also explored, along with the application of antibodies to the measurement of substances of physiological and pharmacological interest. Comprised of six chapters, this volume begins with a discussion on the molecular bases of antigenicity and immunogenicity of proteins, followed by a chapter dealing with blood group antigens. The immunologic effects of low molecular weight antigens are then considered, together with their elicitation of allergic reactions and their tolerance and specific inhibition of the immune response. The next chapter focuses on the use of antibodies to measure substances of physiological and pharmacological interest, with emphasis on the general principle of quantitative immunoassay. The book also analyzes the idiotypy of antibodies before concluding with a description of the antibody functions of immunoglobulin A. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

  • The Biology of B-Lactam Antibiotics

    • 1st Edition
    • Robert B. Morin + 1 more
    • English
    The Biology of ß-Lactam Antibiotics

  • Photosynthesis

    The Biochemistry of Plants
    • 1st Edition
    • M. D. Hatch + 1 more
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 8: Photosynthesis provides information pertinent to the biochemistry of photosynthesis. This book focuses on the photosynthesis of higher plants but some consideration is given to algal and bacterial photosynthesis. Organized into 11 chapters, this volume begins with an overview of the excitation of a light-harvesting pigment by an absorbed light quantum. This text then discusses the evidence to support the hypothesis that chlorophyll–protein complexes are represented at the supramolecular level by some of the intramembranous particles seen on chloroplast freeze-fracture faces. Other chapters consider the absorption of light energy by accessory pigments and transferred to chlorophyll in the blue-green, red, and brown algae. This book discusses as well that certain cyanobacteria respond to the color of the incident light by altering their biliprotein composition. The final chapter deals with dark reaction of photosynthesis. This book is a valuable resource for plant biochemists, neurobiochemists, molecular biologists, senior graduate students, and research workers.

  • Hepatic Plasma Proteins

    Mechanisms of Function and Regulation
    • 1st Edition
    • Barbara H. Bowman
    • English
    Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.

  • The Cell Surface: Mediator of Developmental Processes

    • 1st Edition
    • Stephen Subtelny + 1 more
    • English
    The Cell Surface: Mediator of Developmental Processes contains the papers presented at the 38th Symposium of the Society for Developmental Biology, held at the University of British Columbia in Vancouver, Canada in June 1979. The compendium is divided into three parts. The first part provides a summary of the status of the knowledge about the cell surface, which includes the plasma membrane, its associated cytoskeleton and the variety of surface-associated macromolecules. The second portion focuses on the early development of the cell surface. A wide spectrum of techniques, systems, and results in the study of the cell surface are presented. The last part shows a variety of experimental systems in which the cell surface figures prominently in important developmental events. The results from experiments on plant symbiosis, mammalian teratocarcinomas, adhesion and cell shape, and various extracellular macromolecules are detailed extensively. Cytologists, microbiologists, biologists, and other scientists in allied fields will find the publication very insightful.

  • Enzymology in the Practice of Laboratory Medicine

    Proceedings of a Continuation Course Held at the University of Minnesota, Minneapolis, Minnesota, 10-12 May 1972
    • 1st Edition
    • Philip Blume + 1 more
    • English
    Enzymology in the Practice of Laboratory Medicine focuses on disease processes, enzymatic reactions and activities, and diagnosis and management of diseases. The selection first offers information on developments in the search for mechanisms of enzymic catalysis; application of the spin labeling technique to biological membranes; and the properties of membrane bound enzymes involved in energy transduction processes. Discussions focus on possible clinical interrelationships of membrane function, mitochondrial membrane transactions, mechanical details of chymotryptic catalysis, and physical nature of globular proteins. The text then elaborates on metalloenzymes, enzyme measurement, and enzymology, clinical chemistry, and development of fast analyzers. The publication examines the analytical uses of immobilized enzymes; origin of serum enzymes and the basis for their variation; and the screening methods for glycolytic enzyme deficiencies in red blood cells. Topics include factors contributing to normal variation of enzyme activity, catabolism of enzymes, mechanism of release from cells to plasma, and determination of urea in blood and urine. The selection is a dependable reference for researchers interested in the application of enzymology in laboratory medicine.

  • Bioinformatics for Beginners

    Genes, Genomes, Molecular Evolution, Databases and Analytical Tools
    • 1st Edition
    • Supratim Choudhuri
    • English
    Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options.

  • Modelling and Control of Biotechnical Processes

    Proceedings of the First IFAC Workshop, Helsinki, Finland, August 17-19, 1982
    • 1st Edition
    • A. Halme
    • English
    Modeling and Control of Biotechnical Processes covers the proceedings of the First International Federation of Automatic Control Workshop by the same title, held in Helsinki, Finland on August 17-19, 1982. This book is organized into seven sections encompassing 37 chapters. The opening section deals with the measurement techniques in fermentation processes and the use of automated analyzers to control microbial processes. The next sections consider the concepts of bioreactor modeling and related problems, as well as the modeling and control of biological wastewater treatment processes. Other sections discuss the economic and static optimization, the computer control of production processes, and the application of estimation and identification methods to biotechnological processes. The final sections explore the principles of real-time analysis, use of computer control in specific biotechnical production, process control design, and the modeling of adaptive control. This book is of great value to biotechnologists, biochemists, and control engineers.

  • Gene Function

    FEBS Federation of European Biochemical Societies: 12th Meeting, Dresden, 1978
    • 1st Edition
    • S. Rosenthal + 2 more
    • English
    Gene Function, contains the proceedings of the 12th Meeting of the Federation of European Biochemical Societies held in Dresden, Germany in 1978. The meeting provided a forum for discussing progress in the understanding of gene function and covered topics ranging from the functional organization of chromatin to principles of interactions and recognition models. The role of DNA sequence in the recognition of restriction endonucleases and modification enzymes is also examined, along with gene expression, RNA processing and modification, and isolation and synthesis of genes. Comprised of 49 chapters, this volume begins with an overview of what can be learned from the genetic analysis of the lac repressor, followed by a discussion on the topography of the interaction the lac repressor, RNA polymerase, and histones with DNA. The reader is then introduced to complementarity and recognition code between regulatory proteins and DNA; chromatin replication in vitro; and the cytoplasmic "petite" mutation in Saccharomyces cerevisiae. Subsequent chapters explore arc-like and helical arrangements of nucleosome cores; changes in gene expression during cellular differentiation; polyadenylation and processing of pre-messenger RNA; and the molecular biology of bacteriophages T3 and T7. This book will be of interest to geneticists, biochemists, and molecular biologists.

  • Processing and Turnover of Proteins and Organelles in the Cell

    FEBS Federation of European Biochemical Societies: 12th Meeting, Dresden, 1978
    • 1st Edition
    • S. Rapoport + 1 more
    • English
    Processing and Turnover of Proteins and Organelles in the Cell is a collection of papers that tackles the problems of post-translational processes, along with the dynamics of cell components. The materials in the title are organized thematically. The text first presents articles dealing with post-translational processing, such as the mode of anchoring of sucrase-isomaltase to the small intestinal brush-border membrane and its biosynthetic implications, as well as the decay and restoring in succinate dehydrogenase. The next papers discuss topics related to the selective degradation of proteins, such as selective control of proteinase action in yeast cells and studies of the mechanism and selectivity of intracellular protein breakdown. The final set of papers covers the turnover of organelles, which includes biogenesis and turnover of peroxisomes, and the effect of oxygen on the synthesis of mitochondrial proteins in Saccharomyces cerevisiae. The book will be of great use to microbiologists and biochemists. Scientists from biological science disciplines will also benefit from the text.

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