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Elsevier

Books in Life sciences

  • Nutritional Neuroscience

    From Bench to Bedside
    • 1st Edition
    • Reinaldo B. Oria + 2 more
    • English
    Nutritional Neuroscience: From Bench to Bedside navigates the complex connections between nutrition and neurological health, from neurodevelopmental disorders influenced by early-life malnutrition to the neuroprotective effects of functional foods. Each chapter offers a detailed examination of the latest research in the field, spanning the mechanisms of taste and food processing in the brain, the impact of dietary interventions on inflammation and blood–brain barrier function, and the link between metabolic disorders and neurodegenerative diseases. This book sits at the forefront of nutritional neuroscience, where cutting-edge research meets practical application, and equips its readers with a holistic understanding of how nutrition influences brain health at all ages. Bridging the gap between laboratory discoveries and clinical practice, this book offers a roadmap for future research and interventions in the f ield of nutritional neuroscience.

  • Genetic Regulation of Immune Response Pathways

    • 1st Edition
    • Volume 115
    • English
    Genetic Regulation of Immune Response Pathways, Volume 115 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Chapters explore the genetic regulation of immune cells upon activation, IFN response regulation during viral infections, and the role of noncoding RNAs—including lncRNAs and ncRNAs—in immune regulation and inflammation. Additional sections examine the JAK-STAT signaling pathway in inflammatory and autoimmune diseases as a potential therapeutic target, long noncoding RNAs as key regulators of autoimmunity, and the importance of appropriate cytokine expression in maintaining immune response homeostasis.Together... these contributions provide valuable insights into the molecular and genetic mechanisms underlying immune-mediated processes.

  • Current Trends in Breast Cancer Pathology, Screening, Diagnosis and Treatments

    • 1st Edition
    • Firdos Alam Khan
    • English
    Current Trends in Breast Cancer Pathology, Screening, Diagnosis and Treatments offers an extensive examination of the intricate landscape of breast cancer. This reference not only traverses the entire spectrum from pathology to advanced treatment methodologies but also provides the complexities of bioinformatics research and basic research. By presenting information in a manner that is easily digestible, this book caters to researchers and students across various levels of expertise, facilitating a broader understanding of the subject. Spanning 12 detailed chapters, this book unravels the intricacies of breast cancer development. It provides insights into the cellular and molecular pathologies that underlie the disease, outlines the various stages of breast cancer, and elucidates the diverse methods employed in screening and diagnosis. Moreover, this book explores the available treatment modalities, offering a nuanced perspective on the challenges inherent in breast cancer diagnosis and treatment. This book goes beyond a retrospective analysis and adopts a forward-thinking approach. It not only addresses the current challenges but also casts a forward-looking gaze, identifying potential future research avenues in this critical field. This foresight is essential in shaping the trajectory of advancements in breast cancer research and treatment. Tailor-made for a broad audience, including health professionals, scientists, researchers, health practitioners, and students, its thorough examination of current paradigms ensures that readers gain a nuanced understanding of the complexities involved in breast cancer.

  • Revolutionizing Drug Development

    Harnessing AI and Computational Biology
    • 1st Edition
    • Jen-Tsung Chen
    • English
    Revolutionizing Drug Development: Harnessing AI and Computational Biology presents cutting-edge artificial intelligence (AI) tools, such as machine- and deep-learning models and generative AI, to assist structure-based drug design and clinical trial design and integrate with drug development programs. This book summarizes technical advancements of AI-based technologies and computational biology approaches, highlighting their applications in developing new drugs through discovery, repurposing, and designing, for advancing R&D in the pharmaceutical industry and benefiting precision medicine. This book serves as an ideal reference for students, teachers, professors, and researchers in biological and biomedical sciences, particularly the topics related to bioinformatics, systems biology, pharmacology, and drug development. The readers can efficiently and precisely overview this burning field, which might inspire their future directions of research in drug development and AI-based digital biology.

  • Deep Learning for Cardiac Signal Analysis in Robotic Applications

    • 1st Edition
    • Kapil Gupta + 1 more
    • English
    Deep Learning for Cardiac Signal Analysis in Robotic Applications delves into the transformative role of artificial intelligence in enhancing robotic-assisted cardiovascular procedures. The book starts with the fundamentals of cardiac signals and deep learning, introducing key heart modalities, including the physiological underpinnings and challenges of signals like ECG and BCG and an overview of deep learning architectures relevant to signal processing. Pre-processing and feature extraction techniques are detailed to prepare readers for advanced analysis. Other sections focus on AI-enhanced cardiac signal analysis, covering arrhythmia detection, myocardial ischemia diagnostics, hypertension monitoring via BCG, and explainable AI approaches for fetal arrhythmia monitoring.The final section integrates AI with robotic cardiac surgery, addressing real-time signal integration, AI-guided intervention precision, intraoperative decision support, postoperative monitoring, and future trends in cardiac AI and robotic-assisted surgery. Addressing the complexities of heart signal interpretation amidst the dynamic environment of cardiac surgery, this book meets the critical need for a comprehensive resource that bridges deep learning advances with practical surgical applications. It responds to the challenge of understanding intricate bio-signals, such as ECG, VCG, and BCG, by providing clear explanations, case studies, and methodological insights tailored to improve surgical precision, safety, and patient outcomes.

  • Applied Science and Engineering of Wound Dressings and their Clinical Effectiveness

    From Design Principles to Physiological Performance
    • 1st Edition
    • Amit Gefen
    • English
    Applied Science and Engineering of Wound Dressings and their Clinical Effectiveness: From Design Principles to Physiological Performance addresses the measurable physical, chemical, biomaterial, fluid structure, mechanical and thermal characteristics that are imperative for a dressing to effectively treat acute and chronic wounds. Divided into two parts, the book discusses the properties of wound dressings, their structure, and how they interact with skin surfaces based on scientific investigation and testing. It also discusses potential tradeoffs, including associated costs of manufacturing, clinical performance characteristics of a dressing, e.g., ease of application and removal, the ability of the dressing to stay in place, and more.This book will be valuable for all professionals involved in the treatment of all types of wounds, including biomedical engineers, material scientists, clinicians across all the relevant medical disciplines, industrialists and regulatory professionals in the field of wound care, academics, scientists and entrepreneurs in the field of medical devices, and undergraduate and graduate bioengineering and medical engineering students who are interested in the structure and function of wound dressings.

  • Aflatoxin Management in Crops

    Challenges and Opportunities
    • 1st Edition
    • Sajad Majeed Zargar + 3 more
    • English
    Aflatoxin Management in Crops: Challenges and Opportunities provides a comprehensive look at current insights into aflatoxin contamination in agricultural crops and its effect on human health on global level. With insights from around the globe, it presents the latest advances in the understanding of the contamination and management strategies for aflatoxins in cereals, millets, oilseed, fruits, vegetables, and dairy products. Aflatoxin contamination in crops is a global threat that compromises the safety of food, feed, and also influence the agricultural economy and crop-dependent small scale industries. Crops can be contaminated during the process of harvesting, storing, and transporting by the fungi and leads to the productions of several mycotoxins. Aflatoxin can be extremely harmful if consumed, being linked to cancer-, immune-, and nutritionally related diseases. Aflatoxin Management in Crops: Challenges and Opportunities includes the biology of fungi and the chemistry behind the toxicity level of different aflatoxin strains as well as advances in detection techniques and management strategies. It concludes by exploring the different effects of aflatoxin on human health and regulatory laws to control its contamination.

  • AI and Data Science in Healthcare 5.0

    • 1st Edition
    • Olfa Boubaker
    • English
    AI and Data Science in Healthcare 5.0 delves into the innovative developments in Healthcare 5.0, focusing on smart medical robots, devices, and connected hospitals. It explores the role of robotics in modern healthcare, including advanced wearables enhanced by deep learning. The volume also addresses the integration of blockchain technology, IoT, and cloud computing in healthcare, emphasizing real-time applications in precision healthcare. The discussion extends to energy optimization in smart hospitals, federated learning for IoMT networks, and advanced patient monitoring systems.The volume concludes with an overview of the future opportunities and challenges in Healthcare 5.0.

  • Fundamentals of Plant-Parasitic Nematode Diagnostics, Systematics, and Classification

    • 1st Edition
    • Victor Phani + 1 more
    • English
    Fundamentals of Plant-Parasitic Nematode Diagnostics, Systematics and Classification offers a comprehensive and authoritative resource for researchers, students, and professionals engaged in nematode biosystematics. The microscopic size, morphological plasticity, and broad ecological diversity have long complicated the efforts to accurately identify nematode species and reconstruct their evolutionary relationships. Unlike many other animal groups, the full extent of nematode species richness remains largely unknown, and aside from rare fossilized specimens preserved in amber, paleontological evidence is minimal.This book confronts these challenges by integrating recent advances in molecular systematics with traditional taxonomic frameworks to build a unified reference dataset. It critically surveys the historical classification models and establishes a solid foundation for advancing research on nematode evolution and phylogeny. Rather than concentrating on isolated taxa, it presents a broad conceptual toolkit—encompassing diagnostic techniques, hierarchical organizations, and evolutionary analyses—that directly supports the management of character data and robust taxonomic publications. With its interdisciplinary scope and emphasis on both theoretical and practical diagnostics, this book is poised to become an essential reference for those working in agriculture, plant protection, and nematology.

  • Immunotherapies for Neurologic Diseases

    • 1st Edition
    • Volume 214
    • English
    Immunotherapies for Neurologic Diseases, Volume 214 explores how neuroimmunotherapies intervene by targeting key molecules and pathways responsible for tissue damage in the central and peripheral nervous systems. The book details approved treatments that modulate T-cell signaling, antigen presentation, B cells and their trophic factors, autoantibodies, Fc receptors, complement, cytokines, and cell adhesion molecules. Each chapter includes clear explanations and illustrations, helping clinicians understand the mechanisms of these drugs in autoimmune neurological diseases. The volume serves as a practical and comprehensive guide, making complex therapeutic approaches accessible to medical professionals and students.The second section highlights the latest therapies for major autoimmune neurological diseases, offering step-by-step algorithms and escalation strategies for selecting optimal treatments. Controversies and uncertainties in therapy choices are discussed by leading experts, while additional chapters address emerging immunotherapeutic approaches for neurodegenerative diseases and the evolving concept of treating autoimmune pain. The book also covers practical applications of traditional immunosuppressants, IVIg, and targeted monoclonal antibodies, with dedicated chapters on conditions such as encephalitis, NMOSD, multiple sclerosis, and stiff person syndrome.

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