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    • Cryptic Enzymes and Moonlighting Proteins

      • 1st Edition
      • April 24, 2025
      • Helen Irving + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 7 1 9 6
      • eBook
        9 7 8 0 4 4 3 1 5 7 2 0 2
      Cryptic Enzymes and Moonlighting Proteins, a new volume in the Foundations and Frontiers in Enzymology series, offers a thorough overview of cryptic enzymes and moonlighting proteins in signaling cascades. In early chapters, leading international contributors discuss evolutionary considerations for moonlighting proteins, moonlighting interactions in the extracellular matrix, eukaryotic moonlighting proteins, modulating, moonlighting kinases, moonlighting proteins in neurobiology signaling, metabolic enzymes moonlighting as RNA binding and regulatory proteins. Later, methods-driven chapters discuss practical aspects of identifying hidden moonlighting domains in proteins, computational approaches and bioinformatic tools for the identification of cryptic enzymes, establishing cryptic enzyme interactomes, and assessing contributions of moonlighting proteins to signal cascades.The book also explores recent advances in research and brings together an array of information across different fields to enable better targeting of these exciting proteins and their interactomes. With a clear focus on the role of moonlighting and cryptic enzymes in signal transduction, users will find examples of cryptic enzymes across species, as well as those in human healthy biology and pathogenesis.

    • Kidney Development and Regeneration

      • 1st Edition
      • Volume 163
      • April 23, 2025
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 0 0 3 5
      • eBook
        9 7 8 0 3 2 3 9 9 0 0 4 2
      Kidney Development and Regeneration, Volume 163 provides an up-to-date account of kidney development, congenital disease and regeneration. It has an emphasis on areas of the field that have been moving most quickly over the last few years, and that show potential for further rapid discovery. Each chapter is written by leading researchers, and their approaches range from genetics to cell biology to pharmacology to physiology to pathology to mathematical modeling. The volume is essential reading for those working on renal development, regeneration or pathology, and also those researching related aspects in similar organs.

    • Mechanical Separation Processes in the Food Industry

      • 1st Edition
      • April 23, 2025
      • Seid Mahdi Jafari + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 5 2 3 9
      • eBook
        9 7 8 0 1 2 8 1 9 5 8 8 8
      Mechanical Separation Processes in the Food Industry, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for mechanical separation unit operations, including filtration, centrifugation, sieving, metal detection, sedimentation, etc. These processes and unit operations are very important in the manufacture of products such as cream, fruit juices, beverages, refining of edible oils and sugar. The book's chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment for mechanical separation unit operations.Written by experts in the field of food engineering, and in a simple and dynamic way, this book targets industrial engineers working in the field of food processing and within food factories to make them more familiar with the particular food processing operations and equipment.

    • Emerging Paradigms in Delivery Systems for Antitubercular Therapy

      • 1st Edition
      • April 23, 2025
      • Rajeev Sharma + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 4 0 3 5 5
      • eBook
        9 7 8 0 4 4 3 2 4 0 3 4 8
      Emerging Paradigms in Delivery Systems for Antitubercular Therapy provides an up-to-date and thorough overview of the state-of-the-art of concepts, design, and recent advances in nanomedicines and nanobiotechnology-ba... strategies for the treatment of tuberculosis. The book enables researchers to prepare a variety of nanotechnology-based strategies, investigate their properties, and discover their uses and applications in antitubercular therapy, focusing on advanced nanomaterials that are utilized for encapsulation of nucleic acid, mRNA, DNA, and tuberculosis vaccination.This book covers all major topics that have shaped the development of nanomedicine and propelled it to its current place at the forefront of Nanotechnology based treatment innovation. It will be a welcomed resource for researchers and readers with more and more challenging therapy and biologicals with their possible modifications to be used for the effective therapy of tuberculosis.

    • Epidemiology of Cannabis

      • 1st Edition
      • April 22, 2025
      • Albert Stuart Reece + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 4 9 2 0
      • eBook
        9 7 8 0 4 4 3 1 3 4 9 3 7
      Epidemiology of Cannabis: Genotoxicity, Neurotoxicity, Epigenomics and Aging provides a novel and comprehensive exploration of five areas that have previously been associated with cannabis use, namely mental health in adults and young adults, pediatric autism, congenital anomalies, cancers, and aging. The book also explores the possibility of how these associations might be reflected in overall disease trends at the population health level. This book surveys these five areas in detail and applies cutting-edge analytical software and geospatial space–time analytical techniques to these questions. With all this information gathered into one book in an easily readable form, this book is a reference for clinicians, health science and allied health practitioners, public health and basic science researchers and drug and health regulators interested in these topics. It is also suitable for inclusion in course work and study preparation courses at both the undergraduate and postgraduate levels.

    • Advances in Agronomy

      • 1st Edition
      • Volume 191
      • April 22, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 4 3 8 4
      • eBook
        9 7 8 0 4 4 3 3 1 4 3 9 1
      Advances in Agronomy, Volume 191, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, with this volume presenting chapters on Climate-smart water technologies and strategies for a resilient forage production system, Principles and Application of Nitrogen Management in Precision Agriculture: A Review, No-Till System: a genuine Brazilian technology that meets current global demands, Nutrient management in crop production and dynamics of soil organic carbon in the Indo-Gangetic plains of South Asia, A Global Review of the Impacts of Saltwater Intrusion on Soils and Ecosystems, and more.Other chapters cover Optimizing nitrogen use efficiency in European livestock systems: From feed to plant growth, and Impact of Soil Erosion on Soil Organic Carbon Loss and Its Implications for Carbon Neutrality

    • Apobec Enzymes

      • 1st Edition
      • Volume 713
      • April 21, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 7 8 6 6
      • eBook
        9 7 8 0 4 4 3 3 1 7 8 7 3
      Apobec Enzymes, Volume 713 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Fluorescent shift assay for APOBECs RNA editing, Low Error Sequencing Methods to Detect APOBEC-mediated RNA editing: Circular RNAseq and Safe-Sequencing System, "Safe-Barcode" RNAseq assay for APOBECs RNA editing, DT40 cell system to characterize somatic hypermutation, CH12 cell system to assay AID activity on class switch recombination, Purification of Enzymatically Active APOBEC Proteins from an Insect Cell Expression System, and more.Additional chapters cover Defining genome-wide mutagenic impact of APOBEC3 enzymes, APOBEC-induced mutational assay in yeast, Assays for APOBEC drug discovery, Biochemical assay for the identification of APOBECs inhibitors, An In Vitro Cytidine Deaminase Assay to Monitor APOBEC activity on DNA, Profiling rare C-to-U editing events via direct RNA sequencing, Global quantification of off-target activity by base editors, and so much more.

    • Navigating the Complexities of SARS-CoV-2 Immunobiology

      • 1st Edition
      • Volume 213
      • April 19, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 8 3 2 1
      • eBook
        9 7 8 0 4 4 3 2 3 8 3 3 8
      Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

    • Current Topics in Developmental Biology

      • 1st Edition
      • Volume 162
      • April 18, 2025
      • English
      • Hardback
        9 7 8 0 3 2 3 9 1 2 4 1 9
      • eBook
        9 7 8 0 3 2 3 9 1 2 4 6 4
      Fertilization and Activation of Development, Volume 162 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.Chapters in this new release include Fertilization and the fast block to polyspermy in the African Clawed Frog, Xenopus laevis: A historical perspective, The Mammalian Egg's Zona Pellucida, Fertilization, and Fertility, Function, structure, and regulation of the broadly conserved gamete membrane fusion protein, HAP2, Gamete activation for fertilization and seed development in flowering plants, Paternal contributions to mammalian zygote, and much more.Additional sections cover Ovarian follicle formation and activation, Cytoskeletal dynamics in gamete (pro)nuclear migration across flowering plants, animals, and yeast, and Luteinizing hormone-induced changes in the structure of mammalian preovulatory follicles.

    • Translational Gastroenterology

      • 1st Edition
      • April 18, 2025
      • Adam E.M. Eltorai + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 4 2 6 8
      • eBook
        9 7 8 0 1 2 8 2 1 4 2 7 5
      Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.

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