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Books in Life sciences

  • Cell Biology

    A Laboratory Handbook
    • 1st Edition
    • Julio E Celis
    • English
    Cell Biology: A Laboratory Handbook, Volume 3 is a handbook on cell biology and covers topics ranging from transfer of macromolecules and small molecules to cloning of embryos, transgenics, and gene targeting. Cell-free extracts, permeabilized cell systems, and expression systems are also discussed, along with proteins. Comprised of 58 chapters, this volume begins with a detailed account of microinjection of RNA, DNA, and proteins into somatic cells, followed by an analysis of computer-automated capillary microinjection of macromolecules into living cells. The reader is then introduced to syringe loading as a method for inserting macromolecules into cells in suspension; electroporation of cells; and the use of liposomes in drug targeting. Subsequent chapters focus on the cloning of rabbit embryos by nuclear transplantation; gene targeting by homologous recombination in embryonic stem cells; production and isolation of recombinant viruses; and gel electrophoresis. This book will be of interest to geneticists and molecular biologists.

  • Metabolism and Respiration

    The Biochemistry of Plants
    • 1st Edition
    • David D. Davies
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 2: Metabolism and Respiration is a collection of articles that is largely concerned with the area of intermediary metabolism. This volume contains papers that discuss topics on the production of active C1 groups, photorespiration and the effect of light on respiration. Respiration and related metabolic activity in wounded and infected tissues, the respiration and senescence of plant organs, the effect of temperature on respiration and the assessment of the contributions of metabolic pathways to plant respiration are likewise covered. Biochemists and botanists will find the book highly useful.

  • Progress in Lipid Research

    Volume 18
    • 1st Edition
    • Ralph T. Holman
    • English
    Progress in Lipid Research, Volume 18 focuses on the advancements of processes, methodologies, and approaches involved in lipid research. The selection first elaborates on lipid composition of marine and estuarine invertebrates; role of acylcoenzyme A: cholesterol O-acyltransferase in cholesterol metabolism; and synthesis of acyl lipids in plant tissues. Discussions focus on fatty acid synthesis, turnover of complex lipids, arterial wall and atherosclerosis, cholesteryl ester metabolism, and solubilization. The text then examines the effects of ethanol ingestion on lipid metabolism, including fatty acid oxidation and ketogenesis, lipid peroxidation, plasma triacylglycerols and lipoproteins, phospholipid metabolism, and cholesterol and bile acids. The publication takes a look at lipid metabolism in liver and selected tissues and in the whole body of ruminant animals and the effect of caval shunts on lipid metabolism. Topics include adaptation and regulation of lipid metabolism in the whole animal, lipid metabolism in specific tissues, and the effects of caval shunts on tissue lipids. The text also ponders on lipid metabolism in the neonatal ruminant, as well as transfer of lipids across the placenta, maternal contribution to fetal lipid requirements, and placental lipid metabolism. The selection is a dependable source of data for readers interested in lipid research.

  • Bioinformatics for Beginners

    Genes, Genomes, Molecular Evolution, Databases and Analytical Tools
    • 1st Edition
    • Supratim Choudhuri
    • English
    Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options.

  • Advances in Biomedical Engineering

    Published Under the Auspices of the Biomedical Engineering Society
    • 1st Edition
    • J. H. U. Brown + 1 more
    • English
    Advances in Biomedical Engineering, Volume 2, is a collection of papers that discusses the basic sciences, the applied sciences of engineering, the medical sciences, and the delivery of health services. One paper discusses the models of adrenal cortical control, including the secretion and metabolism of cortisol (the controlled process), as well as the initiation and modulation of secretion of ACTH (the controller). Another paper discusses hospital computer systems—application problems, objective evaluation of technology, and multiple pathways for future hospital computer applications. The possible information paths of an orthotic or prosthetic systems using computing ability include the following components: signal sources, transducers, signal processors, output systems, feedback receptors, and local feedback. Ultrasound energy is a powerful diagnostic tool since it is nondestructive and has asertainability characteristics. The medical technician or researcher can also use gas-phase analytical instruments and analytical systems in investigative chemical methods involving microgram, nanogram or pictogram amounts of individual organic compounds. The collection is suitable for biochemists, microbiologists, bio-engineers, and investigators whose works involve biomedical engineering and physiological research.

  • The Mind–Body Problem

    A Psychobiological Approach
    • 1st Edition
    • Mario Bunge
    • Mario Bunge
    • English
    The Mind–Body Problem: A Psychobiological Approach examines the mind-body problem from a psychobiological perspective. It intends to show that the idea of a separate mental entity is not only unwarranted by the available data and the existing psychological models, but collides head-on with the most fundamental ideas of all modern science and is thus a stumbling block to progress. The book abandons ordinary language in favor of the state space language, which is mathematically precise and is shared by science and scientific philosophy. Comprised of 10 chapters, this monograph begins with an overview of the mind-body problem and its main proposed solutions, classified into main genera: psychophysical monism and psychophysical dualism. In particular, ten views on the mind-body problem are analyzed, along with three main varieties of materialism with regards to the problem: eliminative, reductive (or leveling), and emergentist. The discussion then turns to the notion of a concrete or material system, based on the assumption that behavior is an external manifestation of neural processes. Subsequent chapters explore the specific functions of the central nervous system; sensation and perception; behavior and motivation; memory and learning; thinking and knowing; and consciousness and personality. The book also considers sociality and social behavior in animals before concluding with an assessment of a psychological explanation of the mind, with emphasis on dualism and monism. This work will be of interest to students, academicians, practitioners, and investigators in the fields of psychobiology, psychology, neurophysiology, and philosophy.

  • Modelling and Control of Biotechnical Processes

    Proceedings of the First IFAC Workshop, Helsinki, Finland, August 17-19, 1982
    • 1st Edition
    • A. Halme
    • English
    Modeling and Control of Biotechnical Processes covers the proceedings of the First International Federation of Automatic Control Workshop by the same title, held in Helsinki, Finland on August 17-19, 1982. This book is organized into seven sections encompassing 37 chapters. The opening section deals with the measurement techniques in fermentation processes and the use of automated analyzers to control microbial processes. The next sections consider the concepts of bioreactor modeling and related problems, as well as the modeling and control of biological wastewater treatment processes. Other sections discuss the economic and static optimization, the computer control of production processes, and the application of estimation and identification methods to biotechnological processes. The final sections explore the principles of real-time analysis, use of computer control in specific biotechnical production, process control design, and the modeling of adaptive control. This book is of great value to biotechnologists, biochemists, and control engineers.

  • A Laboratory Manual of Analytical Methods of Protein Chemistry

    Volume 4
    • 1st Edition
    • P. Alexander + 1 more
    • English
    A Laboratory Manual of Analytical Methods of Protein Chemistry, Volume 4 provides information pertinent to the fundamental aspects of protein chemistry. This book discusses the simple and accurate methods of estimating specific proteins. Organized into six chapters, this volume begins with an overview of the composition of acids and experimental conditions for the acid hydrolysis of proteins. This text then examines the advantages of high-voltage electrophoresis for amino acid analysis, which are paralleled by equal advantages in the peptide separation field. Other chapters consider the simple technique of estimating specific proteins, which is one of several based on the phenomenon of antigen-antibody precipitation in gels. This book discusses as well the summations of analyses in weight percentages of the various residues and of the nitrogen of each constituent. The final chapter deals with the electrical properties of molecules. This book is a valuable resource for physicists and research workers.

  • Metabolic Activation of Polynuclear Aromatic Hydrocarbons

    • 1st Edition
    • Wing-Sum Tsang + 1 more
    • English
    Metabolic Activation of Polynuclear Aromatic Hydrocarbons deals with the metabolic activation of polynuclear aromatic hydrocarbons and covers topics ranging from the cytotoxic, mutagenic, and carcinogenic effects of arene oxides to the role of secondary metabolites as ultimate carcinogens. The mechanism of binding of metabolites derived from polynuclear hydrocarbons to key cellular sites is also discussed. This book begins with a brief review of the early work on the mechanism of chemical carcinogenesis by polynuclear hydrocarbons, followed by a detailed survey of pertinent literature in the field. The cytotoxic, mutagenic, and carcinogenic effects of arene oxides are analyzed, along with the solvolytic and nucleophilic reactions of benzo[a]pyrene (BaP) diol epoxides. The discussion then turns to the carcinogenicity, mutagenicity, and cytotoxicity of BaP metabolites; the "Bay-region" theory of carcinogenic activity and perturbational molecular orbital theory; and the mechanism of binding of metabolites derived from polynuclear hydrocarbons to key cellular sites. Research on polycyclic aromatic hydrocarbons pertaining to the "Bay-region" theory is also presented. This monograph will be of interest to chemists, biochemists, and oncologists.

  • Aspects of Developmental and Comparative Immunology

    Proceedings of the 1st Congress of Developmental and Comparative Immunology, 27 July - 1 August 1980, Aberdeen
    • 1st Edition
    • J. B. Solomon
    • English
    Aspects of Developmental and Comparative Immunology contains the proceedings of the 1st Congress of Developmental and Comparative Immunology, held from July 27 to August 1, 1980 in Aberdeen, Scotland. The papers explore various aspects of developmental and comparative immunology and cover topics ranging from the major histocompatibility complex (MHC) and membrane immunoglobulins to idiotypes and diversity, comparative ontogeny, and evolution of lymphoid organ function. Comprised of 105 chapters, this volume begins with an overview of how the host immune system utilizes polymorphic MHC antigens as the principal tool for pseudo-self versus true self distinction. The reader is then introduced to the immunology of earthworms, membrane immunoglobulins, idiotypes, and diversity. Subsequent chapters focus on the evolution of lymphoid organs in vertebrates; differentiation clocks in comparative immunology of mammals and birds; immunorecognition in invertebrates such as insects and gastropods; and the phylogeny of leucocytes in vertebrates and invertebrates. The remaining sections deal with stem cells, immune responses of gut-associated lymphoepithelial tissue, and the ontogeny of resistance to infection as well as the ontogeny of killer cells. Finally, the immunology of fish, amphibians, reptiles, chickens, and mammals is examined. This monograph will be of interest to immunobiologists.

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