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Books in Life sciences

  • Protides of the Biological Fluids

    Proceedings of the Twenty-Ninth Colloquium, 1981
    • 1st Edition
    • Volume 29
    • H. Peeters
    • English
    Protides of the Biological Fluids: An International Review Series Devoted to Proteins and Related Studies, Volume 29: Membrane Proteins, Receptor Ligand Interactions, Monoclonal Antibodies, New Methods focuses on membrane proteins, receptor-ligand interactions, and monoclonal proteins as a reagent. The selection first offers information on H-Y and sex determination and aspects of the difficulties to purify membrane proteins. Topics include solubilization by acylation, influence of supporting media on the aggregation of proteins, solubilization with detergents and organic solvents, and membrane proteins - giant detergent molecules. The text then examines the application of group-specific reagents for hydrophobic labeling and crosslinking of membrane proteins and comparison of secreted and membrane-bound human immunoglobulins M and D. The publication tackles sialoglycoproteins (glycophorins) in the plasma membranes of different cells and their receptor functions and the structures and antigenic properties of human erythrocyte membrane sialoglycoproteins. Discussions focus on the primary structure of human erythrocyte glycophorins, molecular structure of the MN bloodgroup substance, and genetic variants of glycophorin A. The book also takes a look at the glycoproteins of the human syncytiotrophoblasti... plasma membrane and structure and function of a membrane glycoprotein encoded in the adenovirus genome. The selection is a valuable reference for readers interested in membrane proteins, receptor ligand interactions, and monoclonal antibodies.
  • Water-Soluble Vitamins, Hormones, Antibiotics

    • 1st Edition
    • Volume 11
    • Marcel Florkin + 1 more
    • English
    Comprehensive Biochemisty, Volume 11: Water-Soluble Vitamins, Hormones, Antibiotics deals with the organic and physical chemistry of the major organic constituents of living material. This book provides a sound treatment of the important biological high polymers, emphasizing their shape and physical properties. A number of substances peculiar to plants, certain isoprenoids, flavonoids, tannins, lignins, and plant hormones are also covered. This publication likewise discusses the fate of thiamine in living organisms, biologically active isoalloxazines, and auxins with a heterocyclic ring system. Other topics include the yolk-formation hormone of the corpora allata, biochemical aspect of the antibiotics, and miscellaneous antibiotics derivable from amino acids. This volume is a good source for biochemists and specialists conducting work on water-soluble vitamins, hormones, and antibiotics.
  • Current Topics in Bioenergetics

    Volume 4
    • 1st Edition
    • D. Rao Sanadi
    • English
    Current Topics in Bioenergetics, Volume 4 provides information pertinent to the molecular basis for energy transduction in membranous systems. This book presents the developments of relevant techniques in the field of bioenergetics. Organized into eight chapters, this volume begins with an overview of nonequilibrium and fluorescent probes that deal with relatively unexplored areas. This text then discusses the problem of pathways and mechanisms of energy transformations in the cell. Other chapters consider the transport of ions across the plasma membrane of nearly all living cells, which is a necessary condition for the maintenance of the vital life processes. This book discusses as well that bacterial synthesis offers basic and valuable information of general significance and remarkably stimulating challenges with direct bearing on different aspects of the problem of the basic mechanisms involved in biological electron transport-coupled energy conversion. The final chapter deals with the general models for the transport of sodium and potassium. This book is a valuable resource for biologists and biochemists.
  • The Foundations of Genetics

    • 1st Edition
    • F. A. E. Crew
    • J. M. Dodd + 1 more
    • English
    The Foundations of Genetics describes the historical development of genetics with emphasis on the contributions to advancing genetical knowledge and the various applications of genetics. The book reviews the work of Gregor Mendel, his Law of Segregation, and of Ernst Haeckel who suggested that the nucleus is that part of the cell that is responsible for heredity. The text also describes the studies of W. Johannsen on "pure lines," and his introduction of the terms gene, genotype, and phenotype. The book explains the theory of the gene and the notion that hereditary particles are borne by the chromosomes (Sutton-Boveri hypothesis). Of the constituent parts of the nucleus only the chromatin material divides at mitosis and segregates during maturation. Following studies confirm that the chromatin material, present in the form of chromosomes with a constant and characteristic number and appearance for each species, is indeed the hereditary material. The book describes how Muller in 1927, showed that high precision energy radiation is the external cause to mutation in the gene itself if one allele can mutate without affecting its partner. The superstructure of genetics built upon the foundations of Mendelism has many applications including cytogenetics, polyploidy, human genetics, eugenics, plant breeding, radiation genetics, and the evolution theory. The book can be useful to academicians and investigators in the fields of genetics such as biochemical, biometrical, microbial, and pharmacogenetics. Students in agriculture, anthropology, botany, medicine, sociology, veterinary medicine, and zoology should add this text to their list of primary reading materials.
  • Peptides

    Proceedings of the Sixth European Symposium, Athens, September 1963
    • 1st Edition
    • L. Zervas
    • English
    Peptides covers the proceedings of the Sixth European Peptide Symposium, held in Athens, Greece on September 1963. This symposium brings together numerous works on the synthesis, reactions, biological activity, and physico-chemical properties of peptides. This book is organized into seven sections encompassing 46 chapters. The first three sections describe the methods of peptide synthesis, racemization, and degradation of peptide chains. These sections examine the developments in non-enzymatic selective modification and cleavage of peptides, as well as the oxidative modification of specific peptide chain. The succeeding section highlights the total synthesis of natural peptides and peptide analogues and the evaluation of the structure-activity relationships and biological properties of these peptides. These topics are followed by discussions on the synthetic pathways and properties of certain special peptides, along with the accompanying synthesis problems with uncommon amino acids and abnormal peptides. This final section explores the gas-chromatographic studies on the physic-chemical properties of peptides. This book will prove useful to organic chemists, biochemists, and peptide researchers.
  • Gene Activity in Early Development

    • 1st Edition
    • Eric H. Davidson
    • English
    Gene Activity in Early Development reviews the state of knowledge regarding genomic function in the programming and operation of what Bonnet, in 1762, described as "the miracle of epigenesis." The book is divided into four sections. Section I is concerned with gene activity in early embryogenesis, with the time of onset and the nature of embryo genome control, and with recent attempts to analyze the shifting patterns of gene expression as development proceeds. Section II reviews various classic and recent studies relevant to the phenomenon of cytoplasmic localization of morphogenetic potential and discusses the significance, from a contemporary vantage point, of this often neglected area of developmental biology. Section III deals with genomic function in oogenesis, beginning with a general survey of what could be described loosely as the natural history of the oocyte nucleus, and proceeding to current attempts to understand the character and the ultimate function of the oocyte gene products. Section IV discusses various aspects of the general problem of gene regulation in animal cells.
  • Centrifugation in Density Gradients

    • 1st Edition
    • C. A. Price
    • English
    Centrifugation in Density Gradients provides information pertinent to the fundamental aspects of density gradient centrifugation. This book discusses the benefits of density gradient centrifugation to membrane-bound particles. Organized into nine chapters, this book begins with an overview of the method of differential or fractional centrifugation. This text then explores the physical basis of density gradient centrifugation. Other chapters deal with the nuts and bolts of density gradient centrifugation, the construction and composition of gradients, the properties and operation of centrifuge systems, and certain arcane but highly useful procedures. This book discusses as well density gradient centrifugation in the analytical ultracentrifuge. The final chapter deals with a collection of protocols for separating particles ranging in size from whole cells to macromolecules. This book is intended to be suitable for readers who need to separate biological particles. Biologists, chemists, biochemists, cytologists, physiologists, scientists, and research workers will also find this book useful.
  • Introduction to Genetics

    Science of Heredity
    • 1st Edition
    • A. J. S. McMillan
    • English
    Introduction to Genetics: Science of Heredity presents a linear programmed text about hereditary and genetics. This book discusses a variety of topics related to heredity and genetics, including chromosomes, genes, Mendelism, mitosis, and meiosis. Organized into six chapters, this book begins with an overview of some of the experiments that first provide an understanding of heredity and laid the foundation of the science of genetics. This text then provides detailed information about the cell and explains how the essential parts of it reproduce and divide. Other chapters consider how the chromosome theory can explain not only the facts of Mendelism, but also the many complications that arise in genetics. This book discusses as well the problems that can happen during the process of mitosis and meiosis. The final chapter deals with the practical problems that confront the plant breeder. This book is a valuable resource for teachers and students of biology.
  • Techniques in Protein Chemistry IV

    • 1st Edition
    • Ruth Hogue Angeletti
    • English
    Techniques in Protein Chemistry IV compiles papers presented at the Sixth Protein Society Symposium held in San Diego, California in 1992. This book discusses the mass spectrometry in protein sequence and structural investigations; site specific heterogeneity of N-linked oligosaccharides on recombinant human erythropoietin; and modification of thiophosphorylated proteins with extrinsic probes. The cysteine and tryptophan amino acid analysis of ABRF92-AAA; development of separation strategies for proteins by capillary electrophoresis; and peptide mapping of 2-D gel proteins by capillary HPLC are also elaborated. This text likewise covers the single syringe-pump solid-phase protein sequencer; hydrophobic contact density distribution functions; and application of chemical shift calculation to protein structure determination by NMR. This publication is valuable to biologists and students concerned with the developments in mass spectrometry of proteins.
  • Handbook of Immunological Investigations in Children

    Handbooks of Investigation in Children
    • 1st Edition
    • J. Graham Watson + 1 more
    • English
    Handbook of Immunological Investigations in Children presents an extensive examination of the immune system of children. It discusses the fundamental concepts in immunology. It addresses studies in the primary immunodeficiency diseases. Some of the topics covered in the book are the respiratory disorders; renal disorders; gastrointestinal disorders; endocrine disorders; neurological and psychiatric disease; identifications of diseases of the skin; muscle malfunction and connective tissue disorder; and the methods of infections and immunizations. The definition and description of factors influencing blood and blood-forming elements are fully covered. An in-depth account of the factors causing allergies and cardiovascular diseases are provided. The general characteristics of severe combined immunodeficiency are completely presented. A chapter is devoted to usage of immunoglobulin therapy. Another section focuses on the disorders of neutrophils, monocytes, and macrophages. The book can provide useful information to immunologists, pediatricians, doctors, students, and researchers.