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  • Database Directory and Master Indices

    Nucleotide Sequences 1986/1987, Vol. 8
    • 1st Edition
    • Edwin J. Atencio + 2 more
    • English
    Nucleotide Sequences 1986/1987, Volume VIII: Database Directory and Master Indices presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into 13 sections, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main emphasis in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.

  • Carbohydrates: Structure and Function

    The Biochemistry of Plants
    • 1st Edition
    • Jack Preiss
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 3: Carbohydrates: Structure and Function is a compilation of contributions dealing with studies in the area of plant carbohydrates. The articles in this volume are grouped into three sections. The first section deals with topics concerning the monosaccharides and their derivatives found in plants. The integration and control of vital pathways concerned with hexose phosphate metabolism, glycolysis, gluconeogenesis; the metabolism of monosaccharide derivatives; and the formation of sugar nucleotides and their various transformations to the many novel sugar derivatives normally found in plant cell walls and complex carbohydrates are discussed in this section. The second part deals with the occurrence, biosynthesis, and transport of disaccharides and oligosaccharides. The final section of the volume is concerned with the occurrence, structure, and biosynthesis of simple and complex polysaccharides and glycoconjugates associated with cell walls and membranes. Biochemists and botanists will find the book a great reference material.

  • Structure–Function Relationships of Proteolytic Enzymes

    Proceedings of the International Symposium, Copenhagen June 16-18, 1969, No. 37 in the Series of the International Union of Biochemistry Sponsored Symposia
    • 1st Edition
    • P. Desnuelle + 2 more
    • English
    Structure–Function Relationships of Proteolytic Enzymes provides information pertinent to the fundamental aspects of proteolytic enzymes. This book presents the historical role of proteolytic enzyme as a group in protein and enzyme chemistry. Organized into 23 chapters, this book begins with an overview of the results obtained from investigation on the chymotrypsinogens of porcine origin. This text then examines the differences of amino acid sequence between chymotrypsin, trypsin, and elastase that affect the substrate binding site, which reflect the specificity differences between these enzymes. Other chapters consider the kinetic parameters related to the trypsin-catalyzed hydrolysis of several model peptides. This book discusses as well the acetylation of trypsin, which result in functional consequences varying from complete inactivation to promotion of activity. The final chapter deals with the physical properties of stem bromelain in comparison with the data for three other sulfhydryl proteases of plant origin. This book is a valuable resource for enzymologists, microbiologists, and biochemists.

  • Hepatic Plasma Proteins

    Mechanisms of Function and Regulation
    • 1st Edition
    • Barbara H. Bowman
    • English
    Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.

  • The Biology of B-Lactam Antibiotics

    • 1st Edition
    • Robert B. Morin + 1 more
    • English
    The Biology of ß-Lactam Antibiotics

  • Disorders of Mineral Metabolism

    Calcium Physiology
    • 1st Edition
    • Jack W. Coburn + 1 more
    • English
    Disorders of Mineral Metabolism, Volume II: Calcium Physiology is a nine-chapter text that deals with the normal function of calcium, with much emphasis on a host of intracellular functions. This volume discusses the calcium absorption, excretion, and homeostasis, as well as the hormonal modifiers of its metabolism. The role of connective tissue and bone, the major storehouse of body calcium, is reviewed in terms of collagen metabolism. This book will prove useful to biochemists, pathophysiologists, and workers in the medical field.

  • Enzymology in the Practice of Laboratory Medicine

    Proceedings of a Continuation Course Held at the University of Minnesota, Minneapolis, Minnesota, 10-12 May 1972
    • 1st Edition
    • Philip Blume + 1 more
    • English
    Enzymology in the Practice of Laboratory Medicine focuses on disease processes, enzymatic reactions and activities, and diagnosis and management of diseases. The selection first offers information on developments in the search for mechanisms of enzymic catalysis; application of the spin labeling technique to biological membranes; and the properties of membrane bound enzymes involved in energy transduction processes. Discussions focus on possible clinical interrelationships of membrane function, mitochondrial membrane transactions, mechanical details of chymotryptic catalysis, and physical nature of globular proteins. The text then elaborates on metalloenzymes, enzyme measurement, and enzymology, clinical chemistry, and development of fast analyzers. The publication examines the analytical uses of immobilized enzymes; origin of serum enzymes and the basis for their variation; and the screening methods for glycolytic enzyme deficiencies in red blood cells. Topics include factors contributing to normal variation of enzyme activity, catabolism of enzymes, mechanism of release from cells to plasma, and determination of urea in blood and urine. The selection is a dependable reference for researchers interested in the application of enzymology in laboratory medicine.

  • Protection of Functional Groups in Peptide Synthesis

    The Peptides Analysis, Synthesis, Biology, Vol. 3
    • 1st Edition
    • Erhard Gross + 1 more
    • English
    The Peptides: Analysis, Synthesis, Biology, Volume 3: Protection of Functional Groups in Peptide Synthesis focuses on protection of functional groups in peptide synthesis. This book consists of seven chapters. Chapter 1 reviews the large variety of amine protecting groups. The protection of carboxyl groups is described in Chapter 2, while the chemistry of sulfhydryl group protection in peptide synthesis is discussed in Chapter 3. Chapter 4 covers the protection of the hydroxyl groups of serine, threonine, tyrosine, and other hydroxyl-containing amino acids. Differential protection and selective deprotection in peptide synthesis is deliberated in Chapter 5. In chapter 6, the opportunities and constraints of the tactics of minimal protection of side-chain functions during peptide synthesis are reviewed. The last chapter is devoted to the interesting aspects of dual function groups. This volume is recommended for specialists and researchers concerned with peptide and protein research.

  • Proteins and Nucleic Acids

    The Biochemistry of Plants
    • 1st Edition
    • Abraham Marcus
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 6: Proteins and Nucleic Acids provides information pertinent to the nucleic acids and the regulation of the expression of this information. This book presents the processes by which the nucleic acids are finally expressed as proteins. Organized into 14 chapters, this volume begins with an overview of the overall structure of eukaryotic genomes, with emphasis on higher-plant DNA. This text then examines the enzymes involved in the cleavage and degradation of DNA. Other chapters provide a critical assessment of eukaryotic nucleic acid polymerases. This book discusses as well some examples from plant mitochondrial systems. The final chapter deals with two special areas of plant biology where the expression of the nucleic acids is seen in striking relief, the formation of plant tumors, and the growth and expression of plant viruses. This book is a valuable resource for plant biochemists, molecular biologists, senior graduate students, and research workers.

  • Mollusca

    Metabolic Biochemistry and Molecular Biomechanics
    • 1st Edition
    • Peter W. Hochachka
    • English
    The Mollusca, Volume 1: Metabolic Biochemistry and Molecular Biomechanics provides information pertinent to the advances in the traditional areas of biochemistry and in other developed areas that have become a part of molluskan biochemistry. This book discusses the developments in the various aspects of molecular biomechanics and environmental biochemistry. Organized into 11 chapters, this volume begins with an overview of the phylum Mollusca. This text then provides information about the general features of the main classes and their evolution, the anatomical organization of mollusks, and a classification of the primary taxonomic groups of mollusks. Other chapters consider the functional mechanical properties of two protein rubbers found in molluskan connective tissues. This book discusses as well the mechanical properties of molluskan mucins. The final chapter deals with the significance of quinone tanning in mollusks. This book is a valuable resource for researchers of the Mollusca and other phyla, as well as to teachers and qualified graduate students. Biochemists and physiologists will also find this book useful.

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