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  • Agglutination, Complement, Neutralization, and Inhibition

    Methods in Immunology and Immunochemistry, Vol. 4
    • 1st Edition
    • Curtis A. Williams + 1 more
    • English
    Methods in Immunology and Immunochemistry, Volume IV: Agglutination, Complement, Neutralization, and Inhibition provides information pertinent to direct and indirect agglutination reactions. This book covers a variety of topics, including complement-fixation procedures, isolation of complement components, hemolytic intermediates, complement-related proteins, and neutralization reactions. Organized into three chapters, this volume begins with an overview of test-tube agglutinations that are preferred for blood grouping with saline agglutinins that require more than a few minutes for agglutination. This text then describes blood group antibodies that agglutinate red blood cells suspended in saline. Other chapters consider the classical pathway of complement utilization. This book discusses as well the complexity of events leading to hemolysis of erythrocytes by complement. The final chapter deals with the ability of antitoxin to neutralize diphtheria toxin and explains the quantitative relationships between antigen and antibody. This book is a valuable resource for immunologists, scientists, and research workers.

  • The Cell Surface: Mediator of Developmental Processes

    • 1st Edition
    • Stephen Subtelny + 1 more
    • English
    The Cell Surface: Mediator of Developmental Processes contains the papers presented at the 38th Symposium of the Society for Developmental Biology, held at the University of British Columbia in Vancouver, Canada in June 1979. The compendium is divided into three parts. The first part provides a summary of the status of the knowledge about the cell surface, which includes the plasma membrane, its associated cytoskeleton and the variety of surface-associated macromolecules. The second portion focuses on the early development of the cell surface. A wide spectrum of techniques, systems, and results in the study of the cell surface are presented. The last part shows a variety of experimental systems in which the cell surface figures prominently in important developmental events. The results from experiments on plant symbiosis, mammalian teratocarcinomas, adhesion and cell shape, and various extracellular macromolecules are detailed extensively. Cytologists, microbiologists, biologists, and other scientists in allied fields will find the publication very insightful.

  • Conformation in Biology and Drug Design

    The Peptides: Analysis, Synthesis, Biology, Vol. 7
    • 1st Edition
    • Sidney Udenfriend + 2 more
    • English
    The Peptides: Analysis, Synthesis, Biology, Volume 7: Conformation in Biology and Drug Design focuses on the analysis of peptides, emphasizing the use of physical methods in peptide conformational analysis and the relationship of conformational properties of peptides to biological properties. This book consists of nine chapters. Chapter 1 provides a brief overview of the perspective on the application of physical methods to peptide conformational analysis. The use of circular dichroism (CD) spectroscopy to examine the conformational properties of peptides in solution is elaborated in Chapter 2, while the use of fluorescence spectroscopy to examine the special relationships of aromatic side-chain groups to one another is discussed in Chapter 3. In Chapter 4, the use of various theoretical methods to calculate the conformations of peptides is described. The methods used to stimulate peptide conformations and dynamics are outlined in Chapter 5. The last four chapters examine various aspects of the use of nuclear magnetic resonance (NMR) in peptide conformational analysis. This volume is suitable for biologists, specialists, and researchers interested in peptides and proteins.

  • Photosynthesis

    The Biochemistry of Plants
    • 1st Edition
    • M. D. Hatch + 1 more
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 10: Photosynthesis provides information pertinent to the biochemistry of photosynthesis. This book discusses the advances in the field of photosynthesis and emphasizes that not only certain synthetic bacteria and microalgae but also other aquatic phototrophs possess mechanisms for concentrating CO2 or bicarbonate in their cells. Organized into six chapters, this volume begins with an overview of the ways of minimizing the wasteful oxygenase reaction catalyzed by the enzyme. This text then examines the molecular basis underlying the structure of the chloroplast thylakoid membrane and its biogenesis during the maturation of the chloroplast. Other chapters consider the dynamics of the thylakoid membrane, including the role of protein phosphorylation and the lateral distribution of electrical charge and protein components. This book discusses as well the molecular processes governing the development of the organelle. This book is a valuable resource for plant biochemists, neurobiochemists, molecular biologists, senior graduate students, and research workers.

  • Amino Acids and Derivatives

    The Biochemistry of Plants
    • 1st Edition
    • B. J. Miflin
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 5: Amino Acids and Derivatives provides information pertinent to the fundamental aspects of plant biochemistry relating to the metabolism of amino acids with emphasis on amino acids present in proteins. This book discusses the metabolism of sulfur and nitrogen from the inorganic sources available to plants through their incorporation into organic compounds. Organized into 17 chapters, this volume begins with an overview of some aspects of the biochemistry of symbiotic nitrogen fixation. This text then examines the ultrastructure and metabolism of the developing nodule with particular emphasis on interactions between the host legumes and the bacterial symbiont. Other chapters consider the characteristics of the enzymes involved in nitrate and nitrite reduction. The final chapter deals with the essential roles of amino acids and other soluble nitrogenous compounds in plant metabolism. This book is a valuable resource for plant biochemists, neurobiochemists, molecular biologists, senior graduate students, and research workers.

  • Metabolism and Respiration

    The Biochemistry of Plants
    • 1st Edition
    • David D. Davies
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 2: Metabolism and Respiration is a collection of articles that is largely concerned with the area of intermediary metabolism. This volume contains papers that discuss topics on the production of active C1 groups, photorespiration and the effect of light on respiration. Respiration and related metabolic activity in wounded and infected tissues, the respiration and senescence of plant organs, the effect of temperature on respiration and the assessment of the contributions of metabolic pathways to plant respiration are likewise covered. Biochemists and botanists will find the book highly useful.

  • Biochemistry of Metabolism

    The Biochemistry of Plants
    • 1st Edition
    • David D. Davies
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 11: Biochemistry of Metabolism provides information pertinent to the chemical and biochemical aspects of metabolism. This book discusses the control mechanisms of metabolism. Organized into nine chapters, this volume begins with an overview of the history of biochemistry and discusses the developments in the kinetics of regulatory enzymes. This text then examines a theory that explains how subunit interactions modulate the rate of conversion of a substrate into a product. Other chapters consider some relation between cell-wall elongation and cell-wall charge density and explore the subcellular localization of the enzymes of glycolysis. This book discusses as well the regulation of glycolysis and the pentose phosphate pathway. The final chapter deals with the pathways of C1 metabolism that are of prime importance, as the synthesis of several cellular constituents depends directly or indirectly on folate metabolism. This book is a valuable resource for plant biochemists, neurobiochemists, molecular biologists, senior graduate students, and research workers.

  • Monoclonal Antibodies Against Bacteria

    Volume II
    • 1st Edition
    • Alberto J. L. Macario + 1 more
    • English
    Monoclonal Antibodies Against Bacteria, Volume II provides the basis for understanding new developments of practical importance in the health sciences within the area of microbiology and infectious diseases, focusing on advances made possible by monoclonal antibodies. This 12-chapter volume starts with the analysis of streptococcal antigens implicated in the causation of rheumatic fever and heart disease to find ways of inducing protective immunity. The next chapters deal with the detection of staphylococcal enterotoxins in foods and treatment of staphylococcal food poisoning, the classification of meningococcal isolates associated with meningitis and related disorders, and the immunology of brucellosis with emphasis on the problem of distinguishing antibrucella antibodies elicited by vaccination of cattle from antibodies elicited by infection. These topics are followed by discussions of the diagnostic and epidemiologic studies of legionellosis; the identification of antigens in gram-negative bacteria; and the development of means to study and control infections by Pseudomonas in cystic fibrosis and other pathologic conditions. Other chapters explore the analysis of toxigenicity and neutralization of botulinum toxin, the pathogenetic role of Escherichia coli's pili, and study of its antigens to understand regulatory networks of the immune system involving antiidiotypic antibodies. The remaining chapters consider the elucidation of antigenic mosaics of archaebacteria and identification of their molecular signatures in their ecological niches and other life forms. These chapters also look into the combination of bacterial genetics with hybridoma technology for elucidating structure-function relationships in membrane molecules, as well as the strategies, methods, quality control, and other practical aspects connected with industrial production of monoclonal antibodies against bacteria. This book will prove useful to internists, pediatricians, surgeons, dentists, veterinarians, clinical pathologists, and laboratory technologists.

  • Structural RNA, Synthetic, and Unannotated Sequences

    A Compilation from the GenBank® and EMBL data libraries
    • 1st Edition
    • Edwin J. Atencio + 2 more
    • English
    Nucleotide Sequences 1986/1987, Volume VII: Structural RNA, Synthetic, and Unannotated Sequences presents data that reflect the information found in GenBank Release 44.0 of August 1986. This book provides information pertinent to the unique international collaboration between two leading nucleotide sequence data libraries, one based in Europe and one in the United States. Organized into three sections, this volume begins with an overview of the sequences, some basic identifying information, and some of the biological annotations. This text then discusses the EMBL Nucleotide Sequence Data Library, an international center of fundamental research with its main focus in the fields of cell biology, molecular structures, instrumentation, and differentiation. This book discusses as well the GenBank database established in 1982 by the National Institute of General Medical Sciences (NIGMS) of the U.S National Institutes of Health (NIH). This book is a valuable resource for molecular biologists and other investigators collecting the large number of reported DNA and RNA sequences and making them available in computer-readable form.

  • Opioid Peptides: Biology, Chemistry, and Genetics

    The Peptides: Analysis, Synthesis, Biology, Vol. 6
    • 1st Edition
    • Sidney Udenfriend + 1 more
    • English
    The Peptides: Analysis, Synthesis, Biology, Volume 6: Opioid Peptides: Biology, Chemistry, and Genetics presents a biological topic of peptide research. This book is divided into nine chapters. Chapter 1 reviews the opioid peptide precursors and their genes. The proenkephalin and products of its processing are discussed in Chapter 2. In Chapter 3, the role of pro-opiomelanocortin (POMC) as a protein at the interface of the endocrine and nervous systems is examined. Chapter 4 provides a comprehensive account of the biology and chemistry of the dynorphin peptides. The opioid receptors are described in Chapter 5. Chapter 6 evaluates the structure-activity relationships of ?-endorphin, while Chapter 7 considers the conformational analysis of enkephalins and conformation-activit... relationships. The structure-activity relationships among enkephalin peptides are elaborated in Chapter 8. The last chapter is devoted to the clinical significance of opioid peptides in humans. This publication is a good reference for biologists, specialists, and researchers concerned with peptides and proteins.

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