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Books in Life sciences

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    • Light and Biological Rhythms in Man

      • 1st Edition
      • June 28, 2014
      • L. Wetterberg
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 4 4 9 3
      • eBook
        9 7 8 1 4 8 3 2 9 5 4 2 8
      In this volume, current knowledge on light as a regulator of biological rhythms is considered from both basic science and clinical perspectives. Chapters by leading experts cover the whole range of biological rhythms, from infradian and circadian to the longer ultradian rhythms, in a wide variety of mammalian species. The chapters on humans provide a basis on which to establish mechanisms for mediating the therapeutic and physiologically beneficial effects of light as a regulator of rhythms in health and disease.

    • Maximizing Gene Expression

      • 1st Edition
      • May 20, 2014
      • William Reznikoff + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 0 7 1 4 1
      • eBook
        9 7 8 1 4 8 3 1 0 0 8 0 7
      Maximizing Gene Expression focuses on prokaryotic and eukaryotic gene expression. The book first discusses E. coli promoters. Topics include structure analysis, steps in transcription initiation, structure-function correlation, and regulation of transcription initiation. The text also highlights yeast promoters, including elements that select initiation sites, transcription regulation, regulatory proteins, and upstream promoter elements. The text also describes protein coding genes of higher eukaryotes; instability of messenger RNA in bacteria; and replication control of the ColE1-type plasmids. The text then describes translation initiation, including the translation of prokaryotes and eukaryotes. The book puts emphasis on the selective degradation of abnormal proteins in bacteria. Topics include proteins rapidly hydrolyzed in E. coli; intracellular aggregates of abnormal polypeptides; energy requirement and pathway for proteins; proteolytic enzymes in E. coli; and regulation of ion expression. The text also highlights the detection of proteins produced by recombinant DNA techniques and mechanism and practice. The book is a good source of information for readers wanting to study gene expression.

    • Fed-Batch Fermentation

      • 1st Edition
      • September 29, 2014
      • G G Moulton
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 3 6 7 0
      • Hardback
        9 7 8 1 9 0 7 5 6 8 9 2 3
      • eBook
        9 7 8 1 9 0 8 8 1 8 3 3 1
      Fed-batch Fermentation is primarily a practical guide for recombinant protein production in E. coli using a Fed-batch Fermentation process. Ideal users of this guide are teaching labs and R&D labs that need a quick and reproducible process for recombinant protein production. It may also be used as a template for the production of recombinant protein product for use in clinical trials. The guide highlights a method whereby a medium cell density - final Ods = 30-40 (A600) - Fed-batch Fermentation process can be accomplished within a single day with minimal supervision. This process can also be done on a small (2L) scale that is scalable to 30L or more. All reagents (media, carbon source, plasmid vector and host cell) used are widely available and are relatively inexpensive. This method has been used to produce three different protein products following cGMP guidelines for Phase I clinical studies.

    • Clinical Immunobiology

      • 1st Edition
      • Volume 3
      • June 28, 2014
      • Fritz H. Bach + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 9 1 4
      • eBook
        9 7 8 1 4 8 3 2 1 6 3 4 8
      Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual. This volume is composed of 21 chapters and begins with a presentation of the background and issues to which clinical tests would be applied. The succeeding chapters outline the methodological procedures used in the analyses. Other chapters present some examples of the kinds of data that can be generated with the procedures used and provide guidelines for interpretation of the tests. The remaining chapters discuss the value of the immunological test procedures in differential diagnosis and analysis of diseases. These chapters also explore the usefulness of these procedures in prognosis of disease and the consequences of immunological manipulation undertaken for treatment or prevention of disease. This book will be of great value to clinical immunobiologists, biochemists, and researchers.

    • The Third World Congress on Biosensors Abstracts

      • 1st Edition
      • June 28, 2014
      • Abstracts
      • English
      • Paperback
        9 7 8 1 8 5 6 1 7 2 4 2 4
      • eBook
        9 7 8 1 4 8 3 2 9 9 3 5 8
      Biosensors 94: The Third World Congress on Biosensors Abstracts focuses on the progress in the field of biosensors, including immuno-absorbent 'catch' system, surface plasmon resonance, and chemiluminescence. The selection first offers information on the development of a commercial multichannel clinical sensor chip; commercial development and application of biosensors; amperometric biosensors based on dehydrogenase/NAD and heterocyclic quinones; and enzyme-epoxy membrane based semi-automated glucose analyzing system. The text then takes a look at the orientation of antibody fragments to increase TIRF immunosensor efficiency and the development of latex-technology for specific DNA detection with surface plasmon resonance. The book elaborates on gas-phase biosensor for the determination of ethanol vapor; novel electrochemical gas phase biosensors for the detection of phenolic vapors; and the development of an immuno-absorbent 'catch' system for the detection of pesticides and pesticide analogues. The book also ponders on the kinetics of binding of immobilized antibodies under nonequilibrium, flow conditions; flow injection thin-layer cell immunosensor with chemiluminescent detection of peroxidase label; and new optical fiber sensor for detecting chemiluminescence and its application to immunoassay. The selection is a valuable source of data for researchers interested in biosensors.

    • Metabolism and Respiration

      • 1st Edition
      • May 10, 2014
      • David D. Davies
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 6 8 9 9
      • eBook
        9 7 8 1 4 8 3 2 2 0 3 2 1
      The Biochemistry of Plants: A Comprehensive Treatise, Volume 2: Metabolism and Respiration is a collection of articles that is largely concerned with the area of intermediary metabolism. This volume contains papers that discuss topics on the production of active C1 groups, photorespiration and the effect of light on respiration. Respiration and related metabolic activity in wounded and infected tissues, the respiration and senescence of plant organs, the effect of temperature on respiration and the assessment of the contributions of metabolic pathways to plant respiration are likewise covered. Biochemists and botanists will find the book highly useful.

    • Cancer Theranostics

      • 1st Edition
      • March 20, 2014
      • Xiaoyuan Chen + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 2 9 9 2
      • Hardback
        9 7 8 0 1 2 4 0 7 7 2 2 5
      • eBook
        9 7 8 0 1 2 4 0 7 8 8 4 0
      Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives.

    • Regulation of Fatty Acid and Glycerolipid Metabolism

      • 1st Edition
      • May 18, 2014
      • Raymond Dils + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 6 3 4 1
      • eBook
        9 7 8 1 4 8 3 1 4 8 7 6 2
      Regulation of Fatty Acid and Glycerolipid Metabolism is a compilation of papers presented during the 11th Meeting of the Federation of European Biochemical Societies in Copenhagen in 1977. The book deals with the regulation of enzyme activity and the turnover that results from fatty acid metabolism, lipid metabolism in membranes, and disturbed fatty acid metabolism. One study presented in the book shows that cellular fatty acid synthetase levels are significantly decreased by different medium and long chain fatty acids in Candida lypolytica, a kind of yeast. The book also examines the serious incidence of increase in the rate of conversion of glucose to fatty acids when white adipose tissues from rats are exposed to insulin. The selection addresses this increase as an important example of acute hormonal regulation of fatty acid synthesis in mammalian tissues. The text also describes the enzyme adaptation to nutritional and hormonal changes and the role of lipids in membrane fusion. The book presents other studies regarding the incidence of vascular, dietary, and congenital factors on fatty acid metabolism in adipose tissue and liver that are conducted in rats. Another study suggests that hyperinsulinemia is a key factor in the development of the obesity syndrome. Microbiologists, microchemists, and laboratory researchers and scientists dealing with fat metabolism will appreciate this book.

    • Behavior of Nonhuman Primates

      • 1st Edition
      • Volume 5
      • June 28, 2014
      • Allan M. Schrier + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 6 3 3 8
      • eBook
        9 7 8 1 4 8 3 2 5 9 6 0 4
      Behavior of Nonhuman Primates: Modern Research Trends, Volume 5 is a collection of papers on research trends in the study of the various aspects of primate behavior. Chapters in the book discuss topics on the history of the study of cognitive processes in primates; ways in which visual stimuli in monkeys are perceived, stored in memory, and retrieved; and behavior of prosimians. The book will be of value to primatologists, psychologists, and zoologists.

    • Behavior of Nonhuman Primates

      • 1st Edition
      • Volume 4
      • June 28, 2014
      • Allan M. Schrier + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 6 3 2 1
      • eBook
        9 7 8 1 4 8 3 2 5 9 7 4 1
      Behavior of Nonhuman Primates: Modern Research Trends, Volume 4 provides information pertinent to research on behavior of nonhuman primates. This book presents a systematic investigation of memory processes in animals. Organized into four chapters, this volume begins with an overview of the implication of the obvious similarity of monkeys and humans in interproblem learning. This text then presents a series of investigations of the retention of object-discriminatio... learning by learning-set-experie... rhesus monkeys. Other chapters consider the capability of chimpanzees to handle at least rudimentary stages of certain higher mental functions. This book discusses as well the communicative behavior of animals, which is similar to the rest of animal behavior in that it is governed by general perceptual, motor, motivational, and associative laws. The final chapter deals with the main accomplishments of a program designed to teach language to a chimpanzee. This book is a valuable resource for students and research workers.

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