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Books in Life sciences

    • Design and Manufacture of Pharmaceutical Tablets

      • 1st Edition
      • October 9, 2014
      • Reynir Eyjolfsson
      • English
      • Paperback
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      Design and Manufacture of Pharmaceutical Tablets offers real world solutions and outcomes of formulation and processing challenges of pharmaceutical tablets. This book includes numerous practical examples related to actual formulations that have been validated and marketed and covers important data in the areas of stability, dissolution, bioavailibity and processing. It provides important background and theoretical information on design and manufacturing and includes a full section dedicated to design experimental methodology and statistics. In addition, this book offers a a general discussion of excipients used in proper tablet design along with practical examples related to excipients. Drug development scientists in industry and academia, as well as students in the pharmaceutical sciences will greatly benefit from the practical knowledge and case examples provided throughout this book.
    • Antigen-Antibody Reactions In Vivo

      • 1st Edition
      • May 10, 2014
      • Curtis A. Williams + 1 more
      • English
      • Paperback
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      Methods in Immunology and Immunochemistry, Volume V: Antigen-Antibody Reactions In Vivo deals primarily with immune phenomena in tissues or in cell preparations. This book covers a variety of topics, including anaphylaxis, tolerance, immune suppression with chemical agents, radiation effects, antibody synthesis in vitro, immunological methods, and applied electron microscopy. Organized into 10 chapters, this volume begins with an overview of systemic anaphylaxis investigations in other more resistant species. This text then presents the analysis of mechanisms involved in the pathogenesis of the Arthus phenomenon, which shed light on the understanding of other lesions of hypersensitivity. Other chapters consider the effects of antigen–antibody interaction on connective tissue. This book discusses as well the degree and duration of acquired tolerance. The final chapter deals with the application of electron microscopy in the elucidation of the mechanisms of immune reactions. This book is a valuable resource for immunologists, students, and research workers.
    • Wearable Sensors

      • 1st Edition
      • August 14, 2014
      • Edward Sazonov
      • English
      • Paperback
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      • Hardback
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      Written by industry experts, this book aims to provide you with an understanding of how to design and work with wearable sensors. Together these insights provide the first single source of information on wearable sensors that would be a valuable addition to the library of any engineer interested in this field.Wearable Sensors covers a wide variety of topics associated with the development and application of various wearable sensors. It also provides an overview and coherent summary of many aspects of current wearable sensor technology.Both industry professionals and academic researchers will benefit from this comprehensive reference which contains the most up-to-date information on the advancement of lightweight hardware, energy harvesting, signal processing, and wireless communications and networks. Practical problems with smart fabrics, biomonitoring and health informatics are all addressed, plus end user centric design, ethical and safety issues.
    • Postharvest Handling

      • 3rd Edition
      • April 9, 2014
      • Wojciech J. Florkowski + 3 more
      • English
      • Paperback
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      • Hardback
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      Postharvest Handling, Third Edition takes a global perspective in offering a system of measuring, monitoring, and managing produce processing to improve food quality, minimize food waste, reduce risks and uncertainties, and maximize time and resources. This unique resource provides an overview of the postharvest system and its role in the food value chain, and offers essential tools to monitor and control the handling process. It shows how to predict and combat unexpected events (e.g., spoilage), and manage the food quality and safety within a facility. Proven research methods and applications from various viewpoints are available to help you maintain high-quality produce and achieve the highest yields possible. The book also explores current challenges—including oversupply, waste, food safety, lack of resources, sustainability—and best practices for production to thrive in spite of these challenges.
    • Drug Design

      • 1st Edition
      • Volume 9
      • November 26, 2014
      • BAREHAM BAREHAM J
      • English
      • Paperback
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      Drug Design, Volume IX examines various aspects of drug design and covers topics ranging from the consequences of the Hansch paradigm for the pharmaceutical industry to the Masca model of pharmacochemistry. A physicochemical basis for the design of orally active prodrugs is also considered, along with the use of interactive graphics in medicinal chemistry. Comprised of seven chapters, this volume begins with a discussion on efforts to avoid toxicity, not only of drugs, pesticides, and food additives but also of chemicals in general. The reader is then introduced to various aspects of the development of bioactive agents, including the optimization of existing agents by the design of more efficient prodrugs. Other chapters focus on Hansch's paradigm and its application to industrial practice; the application of multivariate statistics to pharmacochemistry; a logico-structural approach to computer-assisted drug design; and spatial arrangements in bioactive molecules. This book will be of interest to pharmacologists, chemists, and those involved in drug design.
    • Best Synthetic Methods

      • 1st Edition
      • December 1, 2014
      • Chris Timperley
      • English
      • Hardback
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      Best Synthetic Methods: Organophosphorus (V) Chemistry provides systematic coverage of the most common classes of pentavalent organophosphorus compounds and reagents (including phosphonyl, phosphoryl, and organophosphates), and allows researchers an easy point of entry into this complex and economically important field. The book follows the Best Synthetic Methods format, containing practical methods, synthetic tips, and shortcuts. Where relevant, articles include toxicity data and historical context for the reactions. Typical analytical and spectroscopic data are also presented to enable scientists to identify key compound characteristics. The book is a valuable companion to research chemists in both academia and industry, summarizing the best practical methods (often originating in difficult-to-access, foreign-language primary literature) in one place. It is ideally suited for those working on industrial applications of these compounds, including insecticides, herbicides, flame retardants, and plasticizers.
    • Molecular and Cellular Aspects of Muscle Function

      • 1st Edition
      • May 9, 2014
      • E. Varga + 2 more
      • English
      • Paperback
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      Advances in Physiological Sciences, Volume 5: Molecular and Cellular Aspects of Muscle Function covers the proceedings of the 28th International Congress of Physiological Sciences, held in Budapest in 1980 (including the proceedings of the satellite symposium on Membrane Control of Skeletal Muscle Function). The book focuses on the molecular and cellular facets of skeletal muscle function. The selection first offers information on the mechanical properties of cross-bridges and their relation to muscle contraction; molecular basis of functional specialization in muscle as induced by innervation; and electrical properties of crustacean muscle membranes. The text then ponders on contractile protein isoforms in developing muscle; effect of age and exercise on minced gastrocnemius muscle regeneration; and contractile proteins of rat gastrocnemius during its regeneration after mincing. The publication examines the behavior of myosin projections in frog striated muscle during isometric contraction; energetics of contracting muscle and its relation to crossbridge mechanisms; and time course of chemical change and energy production during contraction of frog skeletal muscle. The physiological analysis of human myopathy and adaptation in normal and diseased muscle are also discussed. The selection is a vital source of data for readers interested in the cellular and molecular aspects of muscle function.
    • The Cell: Supplementary Volume

      • 1st Edition
      • May 10, 2014
      • Jean Brachet + 1 more
      • English
      • Paperback
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      The Cell: Biochemistry, Physiology, Morphology, Volume VI: Supplementary Volume focuses on the advancements of processes, technologies, and approaches employed in studies on the structure and functions of cells. The selection first offers information on the cytoplasm of Protozoa, fungi, and the aspects of the form and function of plant cells. Topics include special structures, basic genetics, physiology, life cycles and sexuality, special fungal genetics, basal bodies or kinetosomes, mitochondria, and symbiotes in Protozoa. The text then elaborates on sensory and connective tissue cells.Discussions focus on some catabolic processes of connective tissues, formation and cytology of connective tissues, nature of the extracellular constituents, and pseudosensory, neurosensory, and true sensory cells. The selection is a vital reference for researchers interested in the biochemistry, physiology, and morphology of cells.
    • The Evolution of the Microscope

      • 1st Edition
      • May 15, 2014
      • S. Bradbury
      • English
      • Hardback
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      The Evolution of the Microscope covers some of the features of the history of the microscope and the rationale of the design features found in microscopes. The book discusses the first microscopes, the compound microscope in England (1650-1750), simple or single-lens microscopes, and the development of the achromatic microscope. The text also describes the microscope in Victorian times as well as the optical microscope since 1880. The search for greater resolving power such as the ultra-violet and electron microscopes is considered. Scientists and microscopists will find the book invaluable.
    • Disorders of Auditory Function

      • 1st Edition
      • May 10, 2014
      • Ian G. Taylor + 1 more
      • English
      • Paperback
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      Disorders of Auditory Function, Volume III presents the proceedings of the Third Conference of the British Society of Audiology, held at the University of Manchester on July 18–20, 1979. This book provides information pertinent to five major areas of interest to the principles and practice of audiology, namely, pediatric audiology, communication, vestibular function, noise-induced hearing loss, and aural rehabilitation. Organized into four sections encompassing 29 chapters, this volume begins with an overview of the conditions that occur in the first years of life that may result in hearing impairment. This text then examines the methods for the early identification of hearing loss. Other chapters consider the implementation of an effective mass hearing screening program for neonates. This book discusses as well the rules and strategies that hearing-impaired children are using to interpret word order. The final chapter reviews the development in British audiology. This book is a valuable resource for otologists, audiologists, and physicians.