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Books in Life sciences

    • Molecular Genetics Medicine

      • 1st Edition
      • Volume 4
      • November 27, 2014
      • Theodore Friedmann
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 4 5 6 1
      • eBook
        9 7 8 1 4 8 3 2 9 5 5 7 2
      Continuing to keep pace with progress in human molecular genetics, Volume 4 of Molecular Genetic Medicine reviews five new areas of critical importance. Chapter 1 reviews the molecular mechanisms that have beenunraveled in the pathogenesis of eye diseases. The second chapter explains the remarkable new principle if genomic imprinting, or epigenetic modification imposed by parental history. Chapter 3 describes the etiology of amyotrophic lateral sclerosis, or Lou Gehrig's Disease, as effected by superdioxide dismutase function and neuron degeneration. The fourth chapter covers the normal and aberrant functions of peroxisomes, now implicated in many diseases, most notably adrenoleukodystrophy... publicized widelyby the"cure"called Lorenzo's oil. The final chapter summarizes recombination techniques that permit functional new genetic material to be introduced into, and subsequently transmitted through, the germ line of mammalian cells. These amazing methods arehaving profound impacts on medicine and on concepts of the study of normal human development and disease.
    • Single Neuron Computation

      • 1st Edition
      • May 19, 2014
      • Thomas M. McKenna + 2 more
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 6 2 0 6
      • eBook
        9 7 8 1 4 8 3 2 9 6 0 6 7
      This book contains twenty-two original contributions that provide a comprehensive overview of computational approaches to understanding a single neuron structure. The focus on cellular-level processes is twofold. From a computational neuroscience perspective, a thorough understanding of the information processing performed by single neurons leads to an understanding of circuit- and systems-level activity. From the standpoint of artificial neural networks (ANNs), a single real neuron is as complex an operational unit as an entire ANN, and formalizing the complex computations performed by real neurons is essential to the design of enhanced processor elements for use in the next generation of ANNs.The book covers computation in dendrites and spines, computational aspects of ion channels, synapses, patterned discharge and multistate neurons, and stochastic models of neuron dynamics. It is the most up-to-date presentation of biophysical and computational methods.
    • Current Topics in Bioenergetics

      • 1st Edition
      • June 28, 2014
      • C. P. Lee
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 3 5 4 6
      • eBook
        9 7 8 1 4 8 3 2 1 6 9 7 3
      Current Topics in Bioenergetics, Volume 13 presents the biophysical and biochemical approaches that are valuable in some systems and that may be readily be applied to others. This book discusses the function and structure relationship of energy-transducing membranes that has played an essential role in the progress and development in the field of bioenergetics. Organized into six chapters, this volume begins with an overview of the bioenergetics processes that require a molecular description of the structure and reaction mechanisms of the individual energy-transducing catalysts. This text then provides an understanding to the methodology for initiation of an electron paramagnetic resonance (EPR) investigation in this field of research. This book discusses as well the developments in spin label EPR techniques. The final chapter deals with immunological techniques that are used for studying the biochemistry and molecular biology of membrane proteins. This book is a valuable resource for physiologists, biologists, and biochemists.
    • Microencapsulation in the Food Industry

      • 1st Edition
      • June 30, 2014
      • Robert Sobel
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 0 7 9 0
      • Hardback
        9 7 8 0 1 2 4 0 4 5 6 8 2
      • eBook
        9 7 8 0 1 2 4 0 4 7 3 5 8
      Microencapsulation is being used to deliver everything from improved nutrition to unique consumer sensory experiences. It’s rapidly becoming one of the most important opportunities for expanding brand potential. Microencapsulation in the Food Industry: A Practical Implementation Guide is written for those who see the potential benefit of using microencapsulation but need practical insight into using the technology. With coverage of the process technologies, materials, testing, regulatory and even economic insights, this book presents the key considerations for putting microencapsulation to work. Application examples as well as online access to published and issued patents provide information on freedom to operate, building an intellectual property portfolio, and leveraging ability into potential in licensing patents to create produce pipeline.This book bridges the gap between fundamental research and application by combining the knowledge of new and novel processing techniques, materials and selection, regulatory concerns, testing and evaluation of materials, and application-specific uses of microencapsulation.
    • Synthetic Peptides

      • 1st Edition
      • May 10, 2014
      • George R. Pettit
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 4 7 1 6
      • eBook
        9 7 8 1 4 8 3 2 6 2 8 2 6
      Synthetic Peptides discusses racemization, protecting group techniques, peptide bond-forming methodology, amino acids, and dipeptide syntheses. The book explains solid phase synthesis methods, cyclopeptides, nucleopeptides, chromopeptides of the actinomycin D type, and cites examples of syntheses of peptides of different sizes. The text describes tripeptides, tetrapeptides, pentapeptides, hexapeptides, and also undecapeptides to nonadecapeptides. Riniker and colleagues explain the revised structures (for the human and porcine hormone, Asn for Asp at position 25 and Glu for Gin at position 30) for the 39-unit adrenocorticotropic hormone. A synthesis of the 32-unit human calcitonin M is associated with the fragment condensation approach to complex peptides. The book also reviews cyclodepsipeptide valinomycin based on the possible transport of a potassium ion through biological membranes by this substance and the synthesis of a D-Pro analog. The text describes the cyclic decapeptide antibiotic gramicidin S, belonging to a family of similar substances isolated from Bacillus brevi, that can treat certain eye-threatening infections. The book can prove beneficial for biochemists, micro-biologists, cellular investigators, and researchers involved in physiology, oncology or therapeutics.
    • Advances in Lipid Research

      • 1st Edition
      • Volume 23
      • June 28, 2014
      • Rodolfo Paoletti + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 0 1 3
      • eBook
        9 7 8 1 4 8 3 2 1 5 4 4 0
      Advances in Lipid Research, Volume 23 provides information pertinent to mammalian as well as plant metabolism. This book presents important data on apoproteins, which may offer a foothold for further probes of the genetics underlying increased susceptibility to ischemic heart disease. Organized into seven chapters, this volume begins with an overview of the molecular biology of human apolipoproteins B and E. This text then explains the lipid metabolism of dermatophytes and describes their lipid composition and how it may be modulated. Other chapters consider the function, distribution, and biosynthesis of the sterols of fungi and examine the influences of fungal sterols on membrane fluidity. This book discusses as well the biosynthesis and degradation of platelet-activating factor (PAF) as well as its physiological function. The final chapter deals with one specific area of PAF activity, namely, renal processes. This book is a valuable resource for biologist, biochemists, chemists, and clinicians.
    • Immunological Methods

      • 1st Edition
      • May 12, 2014
      • Ivan Lefkovits + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 6 9 6 3 4
      Immunological Methods, Volume III provides information pertinent to the fundamental aspects of immunological methods. This book presents recombinant DNA technology as applied to immunology. Organized into 25 chapters, this volume begins with an overview of the major histocompatibility complex. This text then examines the use of monoclonal antibodies in the identification of lymphocyte membrane antigens and explains the use of monoclonal antibodies in histocompatibility typing. Other chapters consider the methods in two-dimensional electrophoretic analysis of proteins and another to lymphokines that support B cells. This book discusses as well the production and expansion of cloned B and T cell lines and hybridomas. The final chapter deals with the sophisticated methodology used with particular animal species, namely, birds, sheep, and amphibians to probe specific immunological questions. This book is a valuable resource for immunologists and investigators with extensive experience in using immunological methods. Protein chemists and biologists will also find this book useful.
    • Drugs During Pregnancy and Lactation

      • 3rd Edition
      • September 17, 2014
      • Christof Schaefer + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 4 0 8 0 7 8 2
      • eBook
        9 7 8 0 1 2 4 0 7 9 0 1 4
      Drugs During Pregnancy and Lactation, Third Edition is a quick and reliable reference for all those working in disciplines related to fertility, pregnancy, lactation, child health and human genetics who prescribe or deliver medicinal products, and to those who evaluate health and safety risks. Each chapter contains twofold information regarding drugs that are appropriate for prescription during pregnancy and an assessment of the risk of a drug when exposure during pregnancy has already occurred. Thoroughly updated with current regulations, references to the latest pharmacological data, and new medicinal products, this edition is a comprehensive resource covering latest knowledge and findings related to drugs during lactation and pregnancy.
    • Malaria

      • 1st Edition
      • May 12, 2014
      • Julius P. Kreier
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 1 9 7 5
      • eBook
        9 7 8 1 4 8 3 2 5 7 4 7 1
      Malaria: Volume 3, Immunology and Immunization is a collection of papers dealing with malaria parasites, the methods for measuring the immunological response to plasmodia, and the vertebrates host's immune response to plasmodia. Some papers discuss immunization against sporozoites, against the exoerythrocytic stages of malaria parasites, against asexual blood-inhabiting stages of plasmodia, as well as gamete immunization in malaria. One paper describes various separation methods to isolate malaria parasites and their constituents. Another paper discusses in detail the theory and practice of methods used in measuring antibody responses which occur during plasmodial infections, including the antibody response against sporozoites, exoerythrocytic forms, and in the different blood stages. Another paper explains the vertebrate host's immune response to plasmodial infection as a homeostatic physiological response changing along with the progression of the disease. The changes in the dynamic cellular cascade are different as the disease progresses causing death, than when these lead to recovery. Another paper enumerates the parameters which determine malarial infectiousness from one individual to another such as the time of onset, duration, intensity of the blood infections, as well as the maturity, longevity, and rate of production of gametocytes. Pharmacologists, general medical practitioners, investigators, and laboratory technicians involved in malarial research will find the collection very useful.
    • Contemporary Insect Diagnostics

      • 1st Edition
      • October 27, 2014
      • Timothy J. Gibb
      • English
      • Paperback
        9 7 8 0 1 2 4 0 4 6 2 3 8
      • eBook
        9 7 8 0 1 2 4 0 4 6 9 2 4
      Contemporary Insect Diagnostics aids entomologists as they negotiate the expectations and potential dangers of the practice. It provides the reader with methods for networking with regulatory agencies, expert laboratories, first detectors, survey specialists, legal and health professionals, landscape managers, crop scouts, farmers and the lay public. This enables the practitioner and advanced student to understand and work within this network, critically important in a time when each submission takes on its own specific set of expectations and potential ramifications. Insect diagnosticians must be knowledgeable on pests that affect human health, stored foods, agriculture, structures, as well as human comfort and the enjoyment of life. The identification and protection of the environment and the non-target animals (especially beneficial insects) in that environment is also considered a part of insect diagnostics. Additionally, Integrated Pest Management recommendations must include any of a variety of management tactics if they are to be effective and sustainable. This greatly needed foundational information covers the current principles of applied insect diagnostics. It serves as a quick study for those who are called upon to provide diagnostics, as well as a helpful reference for those already in the trenches.