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Elsevier

Books in Life sciences

  • Headache and Migraine Biology and Management

    • 1st Edition
    • Seymour Diamond + 4 more
    • English
    There are two crucial issues in the treatment and management of headache patients: More than 50% of individuals experiencing headache have only been treated symptomatically, with no appropriate diagnosis established; and history and neurologic examination are essential to establishing a diagnosis, and thus selecting appropriate therapy. Headache and Migraine Biology and Management is a practical text that addresses these issues, featuring contributions from expert clinical authors. The book covers in detail topics including chronic and episodic migraine, post-traumatic headache, sinus headache, cluster headache, tension headache, and others. Chapters are also dedicated to treatment subjects, including psychiatric and psychological approaches, medication overuse, inpatient treatment, and pediatric issues. This book is an ideal resource for researchers and clinicians, uniting practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs. This resource is useful to those who want to understand headache biology, treat and manage symptoms, and for those performing research in the headache field.

  • Forest Plans of North America

    • 1st Edition
    • Jacek P. Siry + 5 more
    • English
    Forest Plans of North America presents case studies of contemporary forest management plans developed for forests owned by federal, state, county, and municipal governments, communities, families, individuals, industry, investment organizations, conservation organizations, and others in the United States, Canada, and Mexico. The book provides excellent real-life examples of contemporary forest planning processes, the various methods used, and the diversity of objectives and constraints faced by forest owners. Chapters are written by those who have developed the plans, with each contribution following a unified format and allowing a common, clear presentation of the material, along with consistent treatment of various aspects of the plans. This work complements other books published by members of the same editorial team (Forest Management and Planning, Introduction to Forestry and Natural Resource Management), which describe the planning process and the various methods one might use to develop a plan, but in general do not, as this work does, illustrate what has specifically been developed by landowners and land managers. This is an in-depth compilation of case studies on the development of forest management plans by the different landowner groups in North America. The book offers students, practitioners, policy makers, and the general public an opportunity to greatly improve their appreciation of forest management and, more importantly, foster an understanding of why our forests today are what they are and what forces and tools may shape their tomorrow. Forest Plans of North America provides a solid supplement to those texts that are used as learning tools for forest management courses. In addition, the work functions as a reference for the types of processes used and issues addressed in the early 21st century for managing land resources.

  • The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

    • 1st Edition
    • Joerg Bluemel + 3 more
    • English
    The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area.

  • Biomedical Textiles for Orthopaedic and Surgical Applications

    Fundamentals, Applications and Tissue Engineering
    • 1st Edition
    • Todd Blair
    • English
    Recent concerns over the possible effects of metal-on-metal orthopaedic implants and the evolution of more natural structures made from fibre have made medical device manufacturers consider the potential of fibre. Textiles offer the potential to replace traditional materials with novel fibres which are more suitable for many load bearing applications. Orthopaedics, in particular, is embracing textile technology for repairing, replacing, and regenerating integral pieces of the skeletal system and its associated components. This important new book will provide readers with a comprehensive overview of the role biomedical textiles can play in the orthopaedic field. Chapters in part one will discuss the fundamentals of textiles for orthopaedic applications. Part two will cover textiles for implantable orthopaedic applications whilst the final set of chapters will discuss the role of textiles in orthopaedic tissue engineering.

  • Pituitary Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 44-1
    • Anat Ben-Shlomo
    • English
    This issue of Endocrinology and Metabolism Clinics, edited by Drs. Anat Ben-Shlomo and Maria Fleseriu, is devoted to Pituitary Disorders. Articles in this issue include: Pathogenesis of Pituitary Tumors; Prognostic Clinicopathological Classification of Pituitary Adenomas; Familial Isolated Pituitary Adenomas (FIPA) and Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene; Pitfalls of IGF1 and GH Assays; Acromegaly: Pharmacotherapy; Hypothalamo-pituitar... Axis Testing; Pharmacotherapy of Cushing Disease: New Targets; Prolactinomas; Non-functioning Pituitary Tumors; Cabergoline Use for Pituitary Tumors and Valvular Disorders; Aggressive Atypical Pituitary Tumors and Carcinoma; Outcomes of Endoscopic Transsphenoidal Pituitary Surgery; Efficacy and Complications of Pituitary Irradiation; Hypopituitarism: GH and ACTH Deficiency; Hypophysitis; Hypopituitarism After Traumatic Brain Injury; Quality of Life in Pituitary Diseases; Pituitary and Bone Disease; Pituitary Tumor Management in Pregnancy; and Pituitary Apoplexy.

  • Introductory Experiments on Biomolecules and their Interactions

    • 1st Edition
    • Robert K. Delong + 1 more
    • English
    Introductory Experiments on Biomolecules and their Interactions provides a novel approach to teaching biomolecules in the lab. While featuring the requisite fundamentals, it also captures the author’s experience in industry, thus providing unique, up-to-date experiments which take the learning experience one-step further. The text parallels lectures using a standard biochemistry undergraduate text. Unlike most current lab manuals available in the market which simply emphasize an introduction of techniques, this lab manual provides students with opportunities to demonstrate and prove the knowledge and theories they learn from class.

  • Mucosal Immunology

    • 4th Edition
    • Jiri Mestecky + 5 more
    • English
    Mucosal Immunology, now in its fourth edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. Most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes, making this subject an area of singular importance in the field of immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective, and excellent organization. It covers immune system topics, such as inductive and effector tissues and cells, and development and physiology of the mucosal barrier; diseases in the digestive system, respiratory tract, and genitourinary tract; and immunodeficiency.

  • Diseases of the Nervous System

    • 1st Edition
    • Harald Sontheimer
    • English
    The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system.

  • Principles of Molecular Virology

    • 6th Edition
    • Alan J. Cann
    • English
    Principles of Molecular Virology, Sixth Edition, provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. This fully updated edition explores and explains the fundamental aspects of virology, including the structure of virus particles and genome, replication, gene expression, infection, pathogenesis and subviral agents. In addition, this update reflects advances made in the field, including HIV pathogenesis, cryoelectron microscopy, bioinformatics, and RNA interference.

  • Epilepsy and Brain Tumors

    • 1st Edition
    • Herbert B. Newton + 1 more
    • English
    Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues.

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