Mammalian Cell Membranes

Contributors

Preface


1 Turnover of Mammalian Surface Membranes


1.1 Introduction


1.2 Factors Influencing Turnover


1.3 Domain Turnover


1.4 Turnover of Individual Components


1.5 Conclusions


2 The Influence of the Solute Environment on Membrane Properties


2.1 The 'Structure' of Water


2.2 Interactions between Water, Solutes and Macromolecules


2.3 Water and the Bilayer Membrane


2.4 Influence of Solutes on Membrane Permeability


2.5 Membrane Surface Phenomena


2.6 A Cell Membrane Model


3 The Effects of Hydrostatic Pressure on Cell Membranes


3.1 Introduction


3.2 Molecular Aspects


3.3 Shape and Fine Structure


3.4 Permeability


3.5 Synthesis


3.6 Anesthetics and Various Chemical Agents


3.7 Concluding Remarks


4 The Effects of Radiation on Cell Membranes


4.1 Introduction


4.2 Radiation


4.3 Membrane Structure


4.4 Surface Potential


4.5 Passive Permeability


4.6 Membrane Transport


4.7 Endocytosis


4.8 Cilia


4.9 Conclusions


5 Adenylyl Cyclases: Stimulation by Hormones and Regulation by Nucleotides


5.1 Introduction


5.2 General Properties of Adenylyl Cyclases


5.3 Stimulation by Hormones


5.4 Regulation of Coupling by Nucleotides and Nucleosides


5.5 Mode of Action of Hormones


5.6 Concluding Remarks


6 Endocytosis


6.1 Introduction


6.2 Nomenclature and Definitions


6.3 Occurrence


6.4 Mechanism and Morphological Varieties


6.5 Stages of Endocytosis


6.6 Rate of Endocytosis


6.7 Energy Supply


6.8 Intracellular Fate of Endosomes


6.9 Defecation


6.10 Membrane Regeneration


6.11 Concluding Remarks


7 The Cell Surface and Growth In Vitro


7.1 Introduction


7.2 Cessation of Growth


7.3 Resumption of Growth


7.4 Conclusion


8 Membranes and Aging


8.1 Generalities of the Aging Process


8.2 General Characteristics of the Aging Process in Cell Membranes


8.3 Specific Examples of Membrane Aging


9 Host Cell Membranes in Animal Virus Reproduction


9.1 Introduction


9.2 The Role of Membranes in the Biosynthesis of Enveloped Viruses


9.3 The Role of Membranes in the Biosynthesis of Nonenveloped Viruses


9.4 Virus-Induced Modifications of Membranes


10 Cytoplasmic Membranes in Somatic Cell Interaction and Hybridization


10.1 Association In Vitro of Animal Somatic Cells With Maintenance of Their Integrity


10.2 Cell Fusion and Formation of Polykaryons under Physiological Conditions


10.3 Experimental Cell Fusion and Formation of Somatic Hybrids


10.4 Cell Fusion by Viruses


10.5 Mechanisms Involved In Virus-Induced Cell Fusion


10.6 Secondary Events Following Virus-Induced Fusion of Cell Membranes


10.7 Physical and Chemical Factors Furthering Cell Fusion


10.8 Cell Fusion and Promotion of Viral Activity


10.9 Cell Fusion and Expression of Cell-Surface Antigens


10.10 Cell Fusion and Expression of Particular Cell-Surface Differentiated Features


10.11 Summary and Conclusions

Index