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Elsevier

Books in Life sciences

  • The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

    • 1st Edition
    • Rainer Straub
    • English
    Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting – cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituita... axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation–related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging.

  • Membrane Proteins – Production and Functional Characterization

    • 1st Edition
    • Volume 556
    • English
    Membrane Proteins – Production and Function Characterization a volume of Methods in Enzymology, encompasses chapters from the leading experts in the area of membrane protein biology. The chapters provide a brief overview of the topics covered and also outline step-by-step protocol. Illustrations and case example images are included wherever appropriate to help the readers understand the schematics and general experimental outlines.

  • Global Legislation for Food Contact Materials

    • 1st Edition
    • J.S. Baughan
    • English
    Food contact materials such as packaging, storage containers and processing surfaces can pose a substantial hazard to both food manufacturer and consumer due to the migration of chemicals or other substances from the material to the food, which can cause tainting of flavours and other sensory characteristics, or even illness. This book reviews the main materials used for food contact in terms of the global legislation in place to ensure their safe and effective use. Part One provides an overview of food contact legislation issues such as chemical migration and compliance testing. Part Two looks in detail at the legislation for specific food contact materials and their advantages, hazards and use in industry.

  • Principles of Translational Science in Medicine

    From Bench to Bedside
    • 2nd Edition
    • Martin Wehling
    • English
    Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.

  • Integrative Approaches for Health

    Biomedical Research, Ayurveda and Yoga
    • 1st Edition
    • Bhushan Patwardhan + 2 more
    • English
    Despite spectacular advances, modern medicine faces formidable global challenges in several key areas—notably the persistence of major killer diseases such as malaria, tuberculosis, leprosy, and newer threats including HIV/AIDS, resistant infections, and Ebola. As such, modern medicine has not led to a significant decrease in chronic diseases like diabetes, obesity, and other degenerative and autoimmune diseases. The authors believe that modern medicine needs to experience a paradigm shift, an integration of traditions—in particular from the ancient systems like Ayurveda and Yoga. Integrative Approaches for Health: Biomedical Research, Ayurveda and Yoga brings together the basic principles of interdisciplinary systems approach for an evolving construct of future medicine. Such an approach is already emerging at the cutting edge of current research in omics, bioinformatics, computational and systems biology. Several leading institutions of medicine have adopted Yoga and complementary medicine to widen their reach, and deepen effectiveness in therapeutic practices. The amalgam of modern medicine, with its strengths in scientific rigor, blended with the basic principles of life drawn from Ayurveda and Yoga might evolve into a medicine of tomorrow. Integrative approaches are no longer alternative, perhaps taking these approaches is the only possible way to heal our sick planet. This book introduces important trends and tools for biomedical researchers and physicians alike, to innovate the practice of medicine for the better.

  • The Transformation of Academic Health Centers

    Meeting the Challenges of Healthcare’s Changing Landscape
    • 1st Edition
    • Steven Wartman
    • English
    The Transformation of Academic Health Centers: The Institutional Challenge to Improve Health and Well-Being in Healthcare’s Changing Landscape presents the direct knowledge and vision of accomplished academic leaders whose unique positions as managers of some of the most complex academic and business enterprises make them expert contributors. Users will find invaluable insights and leadership perspectives on healthcare, health professions education, and bio-medical and clinical research that systematically explores the evolving role of global academic health centers with an eye focused on the transformation necessary to be successful in challenging environments. The book is divided into five sections moving from the broad perspective of the role of academic health centers to the role of education, training, and disruptive technologies. It then addresses the discovery processes, improving funding models, and research efficiency. Subsequent sections address the coming changes in healthcare delivery and future perspectives, providing a complete picture of the needs of the growing and influential healthcare sector.

  • Genomics, Physiology and Behaviour of Social Insects

    • 1st Edition
    • Volume 48
    • English
    Physiology, Behavior, Genomics of Social Insects provides comprehensive information on the social insect groups described, including new and unique reviews on emerging model social organisms. The book's interdisciplinary approach integrates behavior, genomics, and physiology, providing readers with great insights into the present state of a rapidly expanding area of research. It also discusses areas where new research tools will bring hope to longstanding problems.

  • Highlights of the Chinese Exposure Factors Handbook

    • 1st Edition
    • Xiaoli Duan
    • English
    The Chinese Research Academy of Environmental Sciences (CRAES) has conducted the Environmental exposure related activity pattern research of Chinese population (Adults). Exposure Factors Handbook of Chinese Population (Adults) was compiled based on the results from this study. Highlights of the Chinese Exposure Factors Handbook is a brief introduction to the content of Exposure Factors Handbook of Chinese Population (Adults). In each chapter, definitions, possible influence factors, and survey methods have been introduced, followed by recommended values for urban/rural areas, different genders, age groups and regions with information of mean, median and P5, P25, P75, P95 values. With the abundant data and tables, readers are provided with an accessible and comprehensive overview of Chinese exposure factors.

  • Protein and Peptide Nanoparticles for Drug Delivery

    • 1st Edition
    • Volume 98
    • English
    Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.

  • Methods in Cilia and Flagella

    • 1st Edition
    • Volume 127
    • English
    The goal of this book is to collect methods and protocols for studying cilia in a wide range of different cell types, so that researchers from many fields of biology can start exploring the role of cilia in their own system.

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